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The map label for this gene is recG [H]

Identifier: 114797135

GI number: 114797135

Start: 2062535

End: 2064613

Strand: Direct

Name: recG [H]

Synonym: HNE_1987

Alternate gene names: 114797135

Gene position: 2062535-2064613 (Clockwise)

Preceding gene: 114799453

Following gene: 114799195

Centisome position: 55.67

GC content: 65.85

Gene sequence:

>2079_bases
ATGCGAGACGAGCGACTCTTTCCGCTGTTTGCCGGCCTTGAGACGCTTACCGGCGTCGGCCCCAAAATGACGCCCCTGCT
GCAGAAGCTGGTGGGCGGGACAACGGTATGGGACCTCGTGCTCCACCTGCCTGACCGCTGGCTGGACCGGCGCGTGCGGG
CAAACTTTGACGAAACCGTGCCTGGTGAAGTCGTCACCGTGAAAGGCGAGGTGCACGCCTATCACCAGCCCTTCAATGAC
CGCTCCCCGCACCGCGTCCAACTTGTTGATTCTACGGGATTTCTGACGCTCTCCTATTTCCGCGCCGACCCGCGCTGGAT
GAAGTCCCAGTTTCCGATCGGGGCCACCCGCATCGTCTCGGGCCGGGTGGAGGAATATCGCGGCGAGCGCCAGATTACCC
ATCCCGACTTCGTGGTCGACCCTGCCAAGGGGGAAGCCCCTCCAGCCGTAGAGCCGATTTACAGCTTGAGTGCCGGCCTC
ACCAACCGCCGGGTCCATACCCTCGCCTTGCAGGCCTTGAGCCTCGTGCCCGATGATTTGCCGGAATGGGCAGATCCGCA
TCTTGTCGCCCAGAAAGGCTGGCCCGCTTTCAAGGAAGCGCTCAGCTGGCAGCATGATCCGAAGGTCTATGACGAAGACC
GCTTCGCCCTGGCGCGGGAACGGCTCGCCTATGACGAAGCCCTCGCCCGCGAATCGGCTTTCGCCCTTGCCCAAGCCGCG
CGGCGCCAGCGCCCGGCACCTATCATCAAGGCCCCGCCCAGCGCCGTGAACCGCCTGATCGACGCGTTGCCCTATCGCCC
CACGGGCGCCCAGATGCGGGCGGCGGCCGACATCAGCTCGGACGTTGCGCGCGGCTATCCGATGCGCCGTTTGCTGCAAG
GCGATGTGGGCGCGGGCAAGACACTGGTGGCCGCCTTTGCCGCGGTTGAGGCCGCCGCAGCGGGTTTTCAATCCGCTTTC
ATGGCGCCCACCGAAGTGCTGGCCCGCCAGCAATATGACACGCTCGACGCCTTGCTTTCGCCGCTTGGCTACACTGTGGC
CGCACTCTCTGGCCGCGACCGGGGCAGCGCCCGCGAAGCCACGCTGATGGGCCTCGCCGACGGGTCGATCCAGATCGTGG
CAGGCACGCACGCCCTCTTTCAGGAGGCGGTGAACTTCCGGAATCTGGGCCTCATCATCGTGGACGAGCAGCACCGGTTC
GGCGTGTCAGACCGGATGAAGCTCGCAGGCAAATCAGAAAACCCGCACATGCTGGTGATGAGCGCCACGCCCATTCCGCG
CACGCTGGCGCAGGCGGTTCACGGCGATCTGGATGTGTCGATCCTCGACGAGAAACCGCCGGGCCGGAAACCGGTCGAAA
CCCGCGCCGTGCCCGATACGCGGCTGGAAGATGTGATCGAAGCCATCGGCCGCGCCTTGAAGCGCGGCGAGCGGGCGTTC
TGGGTCTGCCCGCGCGTGGATATCGAGGACGACGATTCCTCAGCCGTCGTGCGCCATGCCGCCCTGGAAGAAGAGCTGCA
TGTGAAGGCGGGCCTGGTACATGGCCGCCTGAAAGCCTCCGAAAAGGACGCCGCGCTGGAAGACTTCCGCACCGGGCGCA
CACGCATCCTGGTTGCCACCACGGTCATCGAAGTTGGCGTCGATGTGCCTGAAGCCACCATCATGGTGATCGAACGCGCC
GAAGGCTTCGGCCTGGCCCAGCTCCACCAGTTGCGCGGACGCGTGGGCCGGGGCGACAAGCCCTCCTTCTGCCTGCTGCT
CTACCGCCCGCCTCTAGGGGACACGGCGCGGGAGCGGCTCGACACCTTGCGCCGCACCGAAGACGGTTTCGAGATCGCCG
AAGCCGACTTCCGCCTGCGCGGCGCTGGCGACGTTCTGGGGGTTCGGCAAGCGGGCATGACCGACTACCGGATCATTGAT
CTGGCAAAACACGCCGCGCTTCTGGAAATCGCCCGCAAGGATGCCGAAGCCGTTCTGACAGGCGACCCGGACCGCAAGGG
TGAGCGTTGGCAATCGCTGCGCATAGCGCGGGAACTGTTGACGCCGCGCGTGGTGCAGGGCGCCGAAACCGGCTCGTGA

Upstream 100 bases:

>100_bases
GATTGGCCCGGCGCTATTCAACTAGGTTCGGCAGGCCCCGAAGGCAATTGAAACGCAGCAGATTGTTCCGCGCGCCCGCG
CCGCCTAAACTCGCCCCACG

Downstream 100 bases:

>100_bases
AGCCGCTATTTGGCGGGGTTCGAGTTCGGCGCAAGAGGCTGGCCGGGTAACGGATAGTCCGGAACCACAAGGCCACCAGA
GAAGATGATCTTCGCGCCTT

Product: putative ATP-dependent DNA helicase recG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MRDERLFPLFAGLETLTGVGPKMTPLLQKLVGGTTVWDLVLHLPDRWLDRRVRANFDETVPGEVVTVKGEVHAYHQPFND
RSPHRVQLVDSTGFLTLSYFRADPRWMKSQFPIGATRIVSGRVEEYRGERQITHPDFVVDPAKGEAPPAVEPIYSLSAGL
TNRRVHTLALQALSLVPDDLPEWADPHLVAQKGWPAFKEALSWQHDPKVYDEDRFALARERLAYDEALARESAFALAQAA
RRQRPAPIIKAPPSAVNRLIDALPYRPTGAQMRAAADISSDVARGYPMRRLLQGDVGAGKTLVAAFAAVEAAAAGFQSAF
MAPTEVLARQQYDTLDALLSPLGYTVAALSGRDRGSAREATLMGLADGSIQIVAGTHALFQEAVNFRNLGLIIVDEQHRF
GVSDRMKLAGKSENPHMLVMSATPIPRTLAQAVHGDLDVSILDEKPPGRKPVETRAVPDTRLEDVIEAIGRALKRGERAF
WVCPRVDIEDDDSSAVVRHAALEEELHVKAGLVHGRLKASEKDAALEDFRTGRTRILVATTVIEVGVDVPEATIMVIERA
EGFGLAQLHQLRGRVGRGDKPSFCLLLYRPPLGDTARERLDTLRRTEDGFEIAEADFRLRGAGDVLGVRQAGMTDYRIID
LAKHAALLEIARKDAEAVLTGDPDRKGERWQSLRIARELLTPRVVQGAETGS

Sequences:

>Translated_692_residues
MRDERLFPLFAGLETLTGVGPKMTPLLQKLVGGTTVWDLVLHLPDRWLDRRVRANFDETVPGEVVTVKGEVHAYHQPFND
RSPHRVQLVDSTGFLTLSYFRADPRWMKSQFPIGATRIVSGRVEEYRGERQITHPDFVVDPAKGEAPPAVEPIYSLSAGL
TNRRVHTLALQALSLVPDDLPEWADPHLVAQKGWPAFKEALSWQHDPKVYDEDRFALARERLAYDEALARESAFALAQAA
RRQRPAPIIKAPPSAVNRLIDALPYRPTGAQMRAAADISSDVARGYPMRRLLQGDVGAGKTLVAAFAAVEAAAAGFQSAF
MAPTEVLARQQYDTLDALLSPLGYTVAALSGRDRGSAREATLMGLADGSIQIVAGTHALFQEAVNFRNLGLIIVDEQHRF
GVSDRMKLAGKSENPHMLVMSATPIPRTLAQAVHGDLDVSILDEKPPGRKPVETRAVPDTRLEDVIEAIGRALKRGERAF
WVCPRVDIEDDDSSAVVRHAALEEELHVKAGLVHGRLKASEKDAALEDFRTGRTRILVATTVIEVGVDVPEATIMVIERA
EGFGLAQLHQLRGRVGRGDKPSFCLLLYRPPLGDTARERLDTLRRTEDGFEIAEADFRLRGAGDVLGVRQAGMTDYRIID
LAKHAALLEIARKDAEAVLTGDPDRKGERWQSLRIARELLTPRVVQGAETGS
>Mature_692_residues
MRDERLFPLFAGLETLTGVGPKMTPLLQKLVGGTTVWDLVLHLPDRWLDRRVRANFDETVPGEVVTVKGEVHAYHQPFND
RSPHRVQLVDSTGFLTLSYFRADPRWMKSQFPIGATRIVSGRVEEYRGERQITHPDFVVDPAKGEAPPAVEPIYSLSAGL
TNRRVHTLALQALSLVPDDLPEWADPHLVAQKGWPAFKEALSWQHDPKVYDEDRFALARERLAYDEALARESAFALAQAA
RRQRPAPIIKAPPSAVNRLIDALPYRPTGAQMRAAADISSDVARGYPMRRLLQGDVGAGKTLVAAFAAVEAAAAGFQSAF
MAPTEVLARQQYDTLDALLSPLGYTVAALSGRDRGSAREATLMGLADGSIQIVAGTHALFQEAVNFRNLGLIIVDEQHRF
GVSDRMKLAGKSENPHMLVMSATPIPRTLAQAVHGDLDVSILDEKPPGRKPVETRAVPDTRLEDVIEAIGRALKRGERAF
WVCPRVDIEDDDSSAVVRHAALEEELHVKAGLVHGRLKASEKDAALEDFRTGRTRILVATTVIEVGVDVPEATIMVIERA
EGFGLAQLHQLRGRVGRGDKPSFCLLLYRPPLGDTARERLDTLRRTEDGFEIAEADFRLRGAGDVLGVRQAGMTDYRIID
LAKHAALLEIARKDAEAVLTGDPDRKGERWQSLRIARELLTPRVVQGAETGS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=680, Percent_Identity=42.0588235294118, Blast_Score=451, Evalue=1e-127,
Organism=Escherichia coli, GI1787357, Length=398, Percent_Identity=37.9396984924623, Blast_Score=233, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76147; Mature: 76147

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDERLFPLFAGLETLTGVGPKMTPLLQKLVGGTTVWDLVLHLPDRWLDRRVRANFDETV
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCC
PGEVVTVKGEVHAYHQPFNDRSPHRVQLVDSTGFLTLSYFRADPRWMKSQFPIGATRIVS
CCCEEEEECCEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHCCCCCHHHHHH
GRVEEYRGERQITHPDFVVDPAKGEAPPAVEPIYSLSAGLTNRRVHTLALQALSLVPDDL
CHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PEWADPHLVAQKGWPAFKEALSWQHDPKVYDEDRFALARERLAYDEALARESAFALAQAA
CCCCCCCEEECCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRQRPAPIIKAPPSAVNRLIDALPYRPTGAQMRAAADISSDVARGYPMRRLLQGDVGAGK
HHCCCCCCEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCH
TLVAAFAAVEAAAAGFQSAFMAPTEVLARQQYDTLDALLSPLGYTVAALSGRDRGSAREA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCE
TLMGLADGSIQIVAGTHALFQEAVNFRNLGLIIVDEQHRFGVSDRMKLAGKSENPHMLVM
EEEEECCCCEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCEEEEE
SATPIPRTLAQAVHGDLDVSILDEKPPGRKPVETRAVPDTRLEDVIEAIGRALKRGERAF
ECCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
WVCPRVDIEDDDSSAVVRHAALEEELHVKAGLVHGRLKASEKDAALEDFRTGRTRILVAT
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEE
TVIEVGVDVPEATIMVIERAEGFGLAQLHQLRGRVGRGDKPSFCLLLYRPPLGDTARERL
EEHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHH
DTLRRTEDGFEIAEADFRLRGAGDVLGVRQAGMTDYRIIDLAKHAALLEIARKDAEAVLT
HHHHHCCCCCEEECCCEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
GDPDRKGERWQSLRIARELLTPRVVQGAETGS
CCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCC
>Mature Secondary Structure
MRDERLFPLFAGLETLTGVGPKMTPLLQKLVGGTTVWDLVLHLPDRWLDRRVRANFDETV
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCC
PGEVVTVKGEVHAYHQPFNDRSPHRVQLVDSTGFLTLSYFRADPRWMKSQFPIGATRIVS
CCCEEEEECCEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHCCCCCHHHHHH
GRVEEYRGERQITHPDFVVDPAKGEAPPAVEPIYSLSAGLTNRRVHTLALQALSLVPDDL
CHHHHHCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PEWADPHLVAQKGWPAFKEALSWQHDPKVYDEDRFALARERLAYDEALARESAFALAQAA
CCCCCCCEEECCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRQRPAPIIKAPPSAVNRLIDALPYRPTGAQMRAAADISSDVARGYPMRRLLQGDVGAGK
HHCCCCCCEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCH
TLVAAFAAVEAAAAGFQSAFMAPTEVLARQQYDTLDALLSPLGYTVAALSGRDRGSAREA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCE
TLMGLADGSIQIVAGTHALFQEAVNFRNLGLIIVDEQHRFGVSDRMKLAGKSENPHMLVM
EEEEECCCCEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCEEEEE
SATPIPRTLAQAVHGDLDVSILDEKPPGRKPVETRAVPDTRLEDVIEAIGRALKRGERAF
ECCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
WVCPRVDIEDDDSSAVVRHAALEEELHVKAGLVHGRLKASEKDAALEDFRTGRTRILVAT
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEE
TVIEVGVDVPEATIMVIERAEGFGLAQLHQLRGRVGRGDKPSFCLLLYRPPLGDTARERL
EEHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHH
DTLRRTEDGFEIAEADFRLRGAGDVLGVRQAGMTDYRIIDLAKHAALLEIARKDAEAVLT
HHHHHCCCCCEEECCCEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
GDPDRKGERWQSLRIARELLTPRVVQGAETGS
CCCCCCHHHHHHHHHHHHHHCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]