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The map label for this gene is arsC [H]

Identifier: 114332222

GI number: 114332222

Start: 2387160

End: 2387666

Strand: Reverse

Name: arsC [H]

Synonym: Neut_2262

Alternate gene names: 114332222

Gene position: 2387666-2387160 (Counterclockwise)

Preceding gene: 114332223

Following gene: 114332221

Centisome position: 89.73

GC content: 60.55

Gene sequence:

>507_bases
ATGACCGAAAGAATCTATAACGTCCTCATCCTCTGCACCGGCAATTCGGCGCGCAGCATCATGGCCGAAGCTCTCATCAA
CACGATGGGGCAAGGGCGCTTCCGCGCCTACAGCGCCGGCAGTCACCCAACCGGCAAGGTCAATCCCTTCGCCGTCGAAA
AGGTGGAGTCGGTGAATTACCCGACCGAGAATCTGCGCAGCAAGAGCTGGGACGAGTACGCCACGCCCGACGCACCGAAG
ATGGACTTCATCATCACCGTCTGCGACAACGCCGCCGGCGAAATGTGTCCGGTGTGGCCTGGTCAGCCGATCTCGGCGCA
TTGGGGATTTGAAGACCCGGCCGCCGTCGAAGGCACTGACGCCGAGAAGCGCCGGGCCTTCGAACAAACCTTCCGGCACA
TGATGAACCGCGTCCGCCTGTTCGTGAATCTGCCTCTCAAAATGCTTGACCAGACGGCCATCAAGCGCGAGCTGGCGAAC
ATCGGCAAGACCGAGCAGGAAGCATGA

Upstream 100 bases:

>100_bases
GCTATTCCGAACGGAAAGCGGCCGGCCACGTCATCGACGAGGCCACCGATCTTTCATCCATCGCCATTGCTCCCCAGCCA
CTACCAGAAAGCGAAACATC

Downstream 100 bases:

>100_bases
GCGCCGGCGCACAGGCCATCGCCGCGAAGCCGCGCCAGGCCCCGATGAGCGGCTTCGAGCGTTACCTGACGCTGTGGGTG
GCCCTGTGCATCGTCGCCGG

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTERIYNVLILCTGNSARSIMAEALINTMGQGRFRAYSAGSHPTGKVNPFAVEKVESVNYPTENLRSKSWDEYATPDAPK
MDFIITVCDNAAGEMCPVWPGQPISAHWGFEDPAAVEGTDAEKRRAFEQTFRHMMNRVRLFVNLPLKMLDQTAIKRELAN
IGKTEQEA

Sequences:

>Translated_168_residues
MTERIYNVLILCTGNSARSIMAEALINTMGQGRFRAYSAGSHPTGKVNPFAVEKVESVNYPTENLRSKSWDEYATPDAPK
MDFIITVCDNAAGEMCPVWPGQPISAHWGFEDPAAVEGTDAEKRRAFEQTFRHMMNRVRLFVNLPLKMLDQTAIKRELAN
IGKTEQEA
>Mature_167_residues
TERIYNVLILCTGNSARSIMAEALINTMGQGRFRAYSAGSHPTGKVNPFAVEKVESVNYPTENLRSKSWDEYATPDAPKM
DFIITVCDNAAGEMCPVWPGQPISAHWGFEDPAAVEGTDAEKRRAFEQTFRHMMNRVRLFVNLPLKMLDQTAIKRELANI
GKTEQEA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18827; Mature: 18695

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERIYNVLILCTGNSARSIMAEALINTMGQGRFRAYSAGSHPTGKVNPFAVEKVESVNY
CCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHCCC
PTENLRSKSWDEYATPDAPKMDFIITVCDNAAGEMCPVWPGQPISAHWGFEDPAAVEGTD
CHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AEKRRAFEQTFRHMMNRVRLFVNLPLKMLDQTAIKRELANIGKTEQEA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TERIYNVLILCTGNSARSIMAEALINTMGQGRFRAYSAGSHPTGKVNPFAVEKVESVNY
CCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHCCC
PTENLRSKSWDEYATPDAPKMDFIITVCDNAAGEMCPVWPGQPISAHWGFEDPAAVEGTD
CHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AEKRRAFEQTFRHMMNRVRLFVNLPLKMLDQTAIKRELANIGKTEQEA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]