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The map label for this gene is 114332221

Identifier: 114332221

GI number: 114332221

Start: 2386096

End: 2387163

Strand: Reverse

Name: 114332221

Synonym: Neut_2261

Alternate gene names: NA

Gene position: 2387163-2386096 (Counterclockwise)

Preceding gene: 114332222

Following gene: 114332198

Centisome position: 89.71

GC content: 62.83

Gene sequence:

>1068_bases
ATGAGCGCCGGCGCACAGGCCATCGCCGCGAAGCCGCGCCAGGCCCCGATGAGCGGCTTCGAGCGTTACCTGACGCTGTG
GGTGGCCCTGTGCATCGTCGCCGGTGTTGCGCTCGGCCAGGGCCTTCCTGACGTGTTCCAGGCCATAGGCCGCATGGAAG
TGGCCCAGGTCAATTTGCCGGTGGGCCTGCTGATTTGGGTAATGATCGTCCCGATGCTGGTCAAGATCGACTTCGGGGCG
CTGCACCAGGTCAAAGAGCATTGGCGCGGCATCGGCGTCACGCTGTTCGTGAATTGGGCCGTCAAGCCATTCTCGATGGC
CCTGCTGGGGTGGCTGTTCATCCGACAAGTGTTCGCTCCGTTCCTGCCGGCCGATCAACTGGACAGCTACATCGCGGGCT
TGATCTTGCTGGCCGCCGCGCCCTGCACGGCAATGGTGTTCGTGTGGAGCCGCCTTACCAACGGCGACCCGCTTTTCACG
CTCTCGCAAGTGGCTCTGAACGACGCCATCATGATCGTGGCCTTCGCGCCCATCGTCGGCCTGCTGCTGGGCATGTCCTC
GATCTCGGTGCCTTGGGACACGCTGCTGATTTCGGTCGTGCTCTACATCATCGTGCCGGTGATCCTGGCGCAGCTCTTGC
GGCGGCATCTGCTCAAGCAAGGACAGGCCGCCTTTGAACGGGCCATGCAGAAGATCGGGCCGTGGTCGATGGCCGCGCTG
CTGCTGACGTTGGTTCTACTGTTCGCCTTCCAGGGCGAGGCCATCATCCGGCAGCCGTTAGTGATCGCCATGCTAGCCGT
GCCGATCTTGATTCAAGTGTTCTTCAATTCCGGGTTAGCCTACTGGCTGAACAAGCGGGCGGGGGAAAAGCACTCTGTCG
CCTGTCCTTCGGCCCTGATCGGTGCCAGCAACTTCTTCGAGCTGGCCGTGGCGGCCGCCATCAGCTTGTTCGGTCTGCAC
TCCGGCGCTGCATTGGCAACCGTGGTCGGCGTCCTGGTCGAAGTGCCGGTGATGCTGCTGGTCGTGCGCGTGGTGAATCG
CTCGAAGAGCTGGTACGAACGAGGTTGA

Upstream 100 bases:

>100_bases
TGAACCGCGTCCGCCTGTTCGTGAATCTGCCTCTCAAAATGCTTGACCAGACGGCCATCAAGCGCGAGCTGGCGAACATC
GGCAAGACCGAGCAGGAAGC

Downstream 100 bases:

>100_bases
ACATGAGTAGGAAAAAACTGAGGAAATGATTGCAGATTGCCGCGCCGGCCGCTTCCTGGCGCATTCGATCACTGACCTGG
AACACCTAGTATCCATGCTT

Product: bile acid:sodium symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSAGAQAIAAKPRQAPMSGFERYLTLWVALCIVAGVALGQGLPDVFQAIGRMEVAQVNLPVGLLIWVMIVPMLVKIDFGA
LHQVKEHWRGIGVTLFVNWAVKPFSMALLGWLFIRQVFAPFLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGDPLFT
LSQVALNDAIMIVAFAPIVGLLLGMSSISVPWDTLLISVVLYIIVPVILAQLLRRHLLKQGQAAFERAMQKIGPWSMAAL
LLTLVLLFAFQGEAIIRQPLVIAMLAVPILIQVFFNSGLAYWLNKRAGEKHSVACPSALIGASNFFELAVAAAISLFGLH
SGAALATVVGVLVEVPVMLLVVRVVNRSKSWYERG

Sequences:

>Translated_355_residues
MSAGAQAIAAKPRQAPMSGFERYLTLWVALCIVAGVALGQGLPDVFQAIGRMEVAQVNLPVGLLIWVMIVPMLVKIDFGA
LHQVKEHWRGIGVTLFVNWAVKPFSMALLGWLFIRQVFAPFLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGDPLFT
LSQVALNDAIMIVAFAPIVGLLLGMSSISVPWDTLLISVVLYIIVPVILAQLLRRHLLKQGQAAFERAMQKIGPWSMAAL
LLTLVLLFAFQGEAIIRQPLVIAMLAVPILIQVFFNSGLAYWLNKRAGEKHSVACPSALIGASNFFELAVAAAISLFGLH
SGAALATVVGVLVEVPVMLLVVRVVNRSKSWYERG
>Mature_354_residues
SAGAQAIAAKPRQAPMSGFERYLTLWVALCIVAGVALGQGLPDVFQAIGRMEVAQVNLPVGLLIWVMIVPMLVKIDFGAL
HQVKEHWRGIGVTLFVNWAVKPFSMALLGWLFIRQVFAPFLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGDPLFTL
SQVALNDAIMIVAFAPIVGLLLGMSSISVPWDTLLISVVLYIIVPVILAQLLRRHLLKQGQAAFERAMQKIGPWSMAALL
LTLVLLFAFQGEAIIRQPLVIAMLAVPILIQVFFNSGLAYWLNKRAGEKHSVACPSALIGASNFFELAVAAAISLFGLHS
GAALATVVGVLVEVPVMLLVVRVVNRSKSWYERG

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=354, Percent_Identity=24.8587570621469, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38447; Mature: 38316

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGAQAIAAKPRQAPMSGFERYLTLWVALCIVAGVALGQGLPDVFQAIGRMEVAQVNLP
CCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCC
VGLLIWVMIVPMLVKIDFGALHQVKEHWRGIGVTLFVNWAVKPFSMALLGWLFIRQVFAP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
FLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGDPLFTLSQVALNDAIMIVAFAPIVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLLGMSSISVPWDTLLISVVLYIIVPVILAQLLRRHLLKQGQAAFERAMQKIGPWSMAAL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHH
LLTLVLLFAFQGEAIIRQPLVIAMLAVPILIQVFFNSGLAYWLNKRAGEKHSVACPSALI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHH
GASNFFELAVAAAISLFGLHSGAALATVVGVLVEVPVMLLVVRVVNRSKSWYERG
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
SAGAQAIAAKPRQAPMSGFERYLTLWVALCIVAGVALGQGLPDVFQAIGRMEVAQVNLP
CCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCC
VGLLIWVMIVPMLVKIDFGALHQVKEHWRGIGVTLFVNWAVKPFSMALLGWLFIRQVFAP
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHC
FLPADQLDSYIAGLILLAAAPCTAMVFVWSRLTNGDPLFTLSQVALNDAIMIVAFAPIVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLLGMSSISVPWDTLLISVVLYIIVPVILAQLLRRHLLKQGQAAFERAMQKIGPWSMAAL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHH
LLTLVLLFAFQGEAIIRQPLVIAMLAVPILIQVFFNSGLAYWLNKRAGEKHSVACPSALI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHH
GASNFFELAVAAAISLFGLHSGAALATVVGVLVEVPVMLLVVRVVNRSKSWYERG
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]