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The map label for this gene is ackA [H]

Identifier: 114332051

GI number: 114332051

Start: 2208376

End: 2209551

Strand: Direct

Name: ackA [H]

Synonym: Neut_2086

Alternate gene names: 114332051

Gene position: 2208376-2209551 (Clockwise)

Preceding gene: 114332039

Following gene: 114332052

Centisome position: 82.99

GC content: 49.4

Gene sequence:

>1176_bases
ATGAACGAAACCATTCTTGTCCTCAATGCCGGTTCATCCAGTATCAAATACGCACTCTATCGAACAACATACGAAAGTAT
ATCGATAATCTGCCGGGGAAAAATCGAGATCGGCAGCAATACTTCATCCCAGTTTCAAGTCAGGGATTCCCGAGGAGAAT
TACTCTGGCAGCAGCACCTTCACGTTCCTCATCATGAAAGTGCGATAGAAGTGATTTTACAATGGCTGGAGACACAAACA
GATAAACAACGGCCAACGGTAGCAGGCCATCGCGTCGTTCACGGCGGTATATTATTTGACCAGCCAGTCATCATCAATGA
GCAAGTCATCACCCAACTGTTCCAACTGGTTCCACTGGCGCCTCTGCATCAGCTTGACAGCCTGGCGGGAATTGAAACAT
TAAAACGACTCAAGCCAGATTTGCCACAGATTGCTTGTTTCGACACCAGTTTTCATCGTACCATGCCTGATGAAGAACGG
ATTTATGCACTACCTAGCCATTTAACAGATCAGGGAATCCAGCGTTATGGTTTTCATGGCCTTTCCTACGAGTATATTGC
CCATATTCTGCACGATCATCTAGGCGATCGTGCAGCAGGACGCATCGTAGTAGCGCATCTTGGCAATGGTGCCAGCCTGT
GCGCTTTGCGGCAGGGCAAAAGTATCGCTACTACGATGGGATTCACACCATTAGAAGGTTTGCCGATGGGTACACGTTGC
GGCAACCTCGATCCGGCAGTATTGCTCTATCTGATGCGGGAGCAACAAATGAATCACGACATGCTGACAGACTTATTGTA
TCGTCACGCTGGCTTACTAGGTGTTTCCGGCATCAGCGCCGATATGCGTACGTTATTAGCCAGCGATGCCCCCCGCGCCA
AACATGCCGTTGACCTGTTCATCTGGCAGGTATGCCGCCAACTGGGTGCAATGATAGCCGTACTGGAAGGTATCGATGGT
TTGATTTTCACTGCTGGCATCGGCGAACATGCACCACAGATCCGAGCAGGGATCTGTGCTCGCCTCAAATGGCTGTCGAT
CAAGCTTGACGAGTCTGCCAATCAAGCCAATGCCATTCGTATCAGCACTGCTGAAAGCCATATCCCGGTCCTCGTTTTAC
CAACCGATGAAGAGAGCATCATCGCTCACCATACATTACGACTCATCATGGCGTAA

Upstream 100 bases:

>100_bases
TTTGTGTGTTTCACCCACATCACTCTGGATTTCAATAATTCACAAGTTAGCGCATACACCGTGCCAAATCGGTCCCGGCA
AATATTTTTAGGAAATTACC

Downstream 100 bases:

>100_bases
CTTGGGGCGATTCCAGATAACCTGACCTTAATGAGGTATTCAACATGACTCAGACTCCACAATCTCTCACGCCGGATGAA
CTGCAAAAAATAGACGCTTA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNETILVLNAGSSSIKYALYRTTYESISIICRGKIEIGSNTSSQFQVRDSRGELLWQQHLHVPHHESAIEVILQWLETQT
DKQRPTVAGHRVVHGGILFDQPVIINEQVITQLFQLVPLAPLHQLDSLAGIETLKRLKPDLPQIACFDTSFHRTMPDEER
IYALPSHLTDQGIQRYGFHGLSYEYIAHILHDHLGDRAAGRIVVAHLGNGASLCALRQGKSIATTMGFTPLEGLPMGTRC
GNLDPAVLLYLMREQQMNHDMLTDLLYRHAGLLGVSGISADMRTLLASDAPRAKHAVDLFIWQVCRQLGAMIAVLEGIDG
LIFTAGIGEHAPQIRAGICARLKWLSIKLDESANQANAIRISTAESHIPVLVLPTDEESIIAHHTLRLIMA

Sequences:

>Translated_391_residues
MNETILVLNAGSSSIKYALYRTTYESISIICRGKIEIGSNTSSQFQVRDSRGELLWQQHLHVPHHESAIEVILQWLETQT
DKQRPTVAGHRVVHGGILFDQPVIINEQVITQLFQLVPLAPLHQLDSLAGIETLKRLKPDLPQIACFDTSFHRTMPDEER
IYALPSHLTDQGIQRYGFHGLSYEYIAHILHDHLGDRAAGRIVVAHLGNGASLCALRQGKSIATTMGFTPLEGLPMGTRC
GNLDPAVLLYLMREQQMNHDMLTDLLYRHAGLLGVSGISADMRTLLASDAPRAKHAVDLFIWQVCRQLGAMIAVLEGIDG
LIFTAGIGEHAPQIRAGICARLKWLSIKLDESANQANAIRISTAESHIPVLVLPTDEESIIAHHTLRLIMA
>Mature_391_residues
MNETILVLNAGSSSIKYALYRTTYESISIICRGKIEIGSNTSSQFQVRDSRGELLWQQHLHVPHHESAIEVILQWLETQT
DKQRPTVAGHRVVHGGILFDQPVIINEQVITQLFQLVPLAPLHQLDSLAGIETLKRLKPDLPQIACFDTSFHRTMPDEER
IYALPSHLTDQGIQRYGFHGLSYEYIAHILHDHLGDRAAGRIVVAHLGNGASLCALRQGKSIATTMGFTPLEGLPMGTRC
GNLDPAVLLYLMREQQMNHDMLTDLLYRHAGLLGVSGISADMRTLLASDAPRAKHAVDLFIWQVCRQLGAMIAVLEGIDG
LIFTAGIGEHAPQIRAGICARLKWLSIKLDESANQANAIRISTAESHIPVLVLPTDEESIIAHHTLRLIMA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=394, Percent_Identity=36.8020304568528, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1788633, Length=404, Percent_Identity=35.1485148514851, Blast_Score=221, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 43283; Mature: 43283

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETILVLNAGSSSIKYALYRTTYESISIICRGKIEIGSNTSSQFQVRDSRGELLWQQHL
CCCEEEEEECCCCCEEEEEEEEHHHHEEEEEEEEEEECCCCCCEEEEECCCCHHHHHHHC
HVPHHESAIEVILQWLETQTDKQRPTVAGHRVVHGGILFDQPVIINEQVITQLFQLVPLA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEECCCEEECHHHHHHHHHHCCCC
PLHQLDSLAGIETLKRLKPDLPQIACFDTSFHRTMPDEERIYALPSHLTDQGIQRYGFHG
HHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCCEEECCCHHHHHHHHHHCCCC
LSYEYIAHILHDHLGDRAAGRIVVAHLGNGASLCALRQGKSIATTMGFTPLEGLPMGTRC
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCC
GNLDPAVLLYLMREQQMNHDMLTDLLYRHAGLLGVSGISADMRTLLASDAPRAKHAVDLF
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCCHHHHHHHH
IWQVCRQLGAMIAVLEGIDGLIFTAGIGEHAPQIRAGICARLKWLSIKLDESANQANAIR
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHEEEEEEEECCCCCCCCEEE
ISTAESHIPVLVLPTDEESIIAHHTLRLIMA
EEECCCCCCEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNETILVLNAGSSSIKYALYRTTYESISIICRGKIEIGSNTSSQFQVRDSRGELLWQQHL
CCCEEEEEECCCCCEEEEEEEEHHHHEEEEEEEEEEECCCCCCEEEEECCCCHHHHHHHC
HVPHHESAIEVILQWLETQTDKQRPTVAGHRVVHGGILFDQPVIINEQVITQLFQLVPLA
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEECCCEEECHHHHHHHHHHCCCC
PLHQLDSLAGIETLKRLKPDLPQIACFDTSFHRTMPDEERIYALPSHLTDQGIQRYGFHG
HHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCCEEECCCHHHHHHHHHHCCCC
LSYEYIAHILHDHLGDRAAGRIVVAHLGNGASLCALRQGKSIATTMGFTPLEGLPMGTRC
CCHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCC
GNLDPAVLLYLMREQQMNHDMLTDLLYRHAGLLGVSGISADMRTLLASDAPRAKHAVDLF
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCCHHHHHHHH
IWQVCRQLGAMIAVLEGIDGLIFTAGIGEHAPQIRAGICARLKWLSIKLDESANQANAIR
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHEEEEEEEECCCCCCCCEEE
ISTAESHIPVLVLPTDEESIIAHHTLRLIMA
EEECCCCCCEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA