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The map label for this gene is frr

Identifier: 114331998

GI number: 114331998

Start: 2147970

End: 2148527

Strand: Reverse

Name: frr

Synonym: Neut_2032

Alternate gene names: 114331998

Gene position: 2148527-2147970 (Counterclockwise)

Preceding gene: 114331999

Following gene: 114331997

Centisome position: 80.74

GC content: 45.34

Gene sequence:

>558_bases
ATGATTGCTGATATAAAAAAGGCTACTGAGCAGAAAATGCAAAAAAGCCTGGATGCACTTAAAGTTGATTTCAGCAAAGT
AAGAAGTGGACGTCCACATACAGGGCTGCTGGATCATATAACAGTTGACTACTATGGAACACCTACACCGATCAGACAGC
TTGCGAATGTAACTCTGGCTGATGCGCGGACTATAGGCGTTATTCCATGGGATAAAAAAGCATTTTCAGCCATTGAAAAA
GCGATACGAGATTCTGATATGGGCTTGAATCCGATGACTGCGGGTGAAATGGTGAGGGTGCCTATGCCTCCCTTGACAGA
AGAAAGACGCAAGGACTTGACCAAGATTGTTAGAACGGAAGCGGAAACAGCTCGTATCGCGATGAGGAATATTCGGCGTG
ATGCTAATACCCAGTTGAAAGAATTGTTGAAGGACAAGTTGATCGCGGAAGATGAAGATCGCCGTGCGCAGGATGATATC
CAGAAACTGACAGACCGATATATTGCCGAGGTAGACAAGCTGCTGCAAGCCAAAGAAGCAGAATTGATGGCTGTCTGA

Upstream 100 bases:

>100_bases
ATTTTTGGACATTATCTAAAATATCGTTATTCCTCGCGGTATATGGCAGAGCACATGTGCATTGTTGTAATCGCTTTTTA
ATGTCAATATCTACTTAAAT

Downstream 100 bases:

>100_bases
TATATGCCTTCAATATTGAGTTCAACTCGTGGAATCCCGGAAACCGGGATGATACCCAAGCATATCGCTATTATCATGGA
TGGTAATGGCCGGTGGGCAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIADIKKATEQKMQKSLDALKVDFSKVRSGRPHTGLLDHITVDYYGTPTPIRQLANVTLADARTIGVIPWDKKAFSAIEK
AIRDSDMGLNPMTAGEMVRVPMPPLTEERRKDLTKIVRTEAETARIAMRNIRRDANTQLKELLKDKLIAEDEDRRAQDDI
QKLTDRYIAEVDKLLQAKEAELMAV

Sequences:

>Translated_185_residues
MIADIKKATEQKMQKSLDALKVDFSKVRSGRPHTGLLDHITVDYYGTPTPIRQLANVTLADARTIGVIPWDKKAFSAIEK
AIRDSDMGLNPMTAGEMVRVPMPPLTEERRKDLTKIVRTEAETARIAMRNIRRDANTQLKELLKDKLIAEDEDRRAQDDI
QKLTDRYIAEVDKLLQAKEAELMAV
>Mature_185_residues
MIADIKKATEQKMQKSLDALKVDFSKVRSGRPHTGLLDHITVDYYGTPTPIRQLANVTLADARTIGVIPWDKKAFSAIEK
AIRDSDMGLNPMTAGEMVRVPMPPLTEERRKDLTKIVRTEAETARIAMRNIRRDANTQLKELLKDKLIAEDEDRRAQDDI
QKLTDRYIAEVDKLLQAKEAELMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=175, Percent_Identity=30.8571428571429, Blast_Score=80, Evalue=8e-16,
Organism=Homo sapiens, GI291042689, Length=151, Percent_Identity=31.1258278145695, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=60.1092896174863, Blast_Score=224, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=31.0344827586207, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_NITEC (Q0AEH7)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748220.1
- ProteinModelPortal:   Q0AEH7
- SMR:   Q0AEH7
- STRING:   Q0AEH7
- GeneID:   4273244
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2032
- NMPDR:   fig|335283.3.peg.2493
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q0AEH7
- ProtClustDB:   PRK00083
- BioCyc:   NEUT335283:NEUT_2032-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20985; Mature: 20985

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIADIKKATEQKMQKSLDALKVDFSKVRSGRPHTGLLDHITVDYYGTPTPIRQLANVTLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHH
DARTIGVIPWDKKAFSAIEKAIRDSDMGLNPMTAGEMVRVPMPPLTEERRKDLTKIVRTE
CCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHH
AETARIAMRNIRRDANTQLKELLKDKLIAEDEDRRAQDDIQKLTDRYIAEVDKLLQAKEA
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMAV
HHHCC
>Mature Secondary Structure
MIADIKKATEQKMQKSLDALKVDFSKVRSGRPHTGLLDHITVDYYGTPTPIRQLANVTLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCCCHHHHHHHHHHHH
DARTIGVIPWDKKAFSAIEKAIRDSDMGLNPMTAGEMVRVPMPPLTEERRKDLTKIVRTE
CCCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHH
AETARIAMRNIRRDANTQLKELLKDKLIAEDEDRRAQDDIQKLTDRYIAEVDKLLQAKEA
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMAV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA