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The map label for this gene is yaeL [C]

Identifier: 114331994

GI number: 114331994

Start: 2143689

End: 2145056

Strand: Reverse

Name: yaeL [C]

Synonym: Neut_2028

Alternate gene names: 114331994

Gene position: 2145056-2143689 (Counterclockwise)

Preceding gene: 114331995

Following gene: 114331993

Centisome position: 80.61

GC content: 48.98

Gene sequence:

>1368_bases
ATGACACTGCTCTCAACTATTTTTGCATTCGTAATTGCACTGGGTCTACTGATCACTTTTCACGAATTTGGCCATTATCT
GGTCGCTCGTTGGTGTGGAGTCAAGGTGCTGCGCTTTTCTCTCGGATTTGGCCAGCCCTTGTTTAAAAAACGCCTTGGTA
ATGATCAGACGGAATGGGTGGTCGCTGCGATCCCTCTGGGGGGATATGTCAAGATGCTGGATGAACGGGAAGGGCGGGTT
CCCGCTGACGAACTTCCACGTGCATTTAACCGACAACCTGTTTCCAAGCGTTTCGCTATCGTGGTTGCAGGCCCTGTGGC
GAACTTCTTATTGGCTATTCTGCTGTACTGGTTACTTTTTATACTCGGTGTCAGTGGTGTAAAGCCAATCCTGGGGGAAA
TTGAACCCGCGACACTTGCGGCTTCAGCAGGTTTCAGAAACGGGGATACCATTACCGGGATCGGCGACCAGGCAATTACC
ACCTGGCAGGAAGCCCGACTGCTACTGCTGGACAATGCAGTAGACAAGAATCCTGATGTCAGGATAACAGTAACAGGCGA
AAGTGGAATTTCTCGTCAGCTTAAACTCGATATGAGCAGTCTTGGCGCAGAAGATCTTGAAAGTGATTTTCTGAATCGAC
TGGGTTTGAGTGTTTATCGGCCAATTGTTGCCCCAGTTATTGATCAGGTGATGGTTGGCGGGGCGGCAGAACGCGCGGGT
CTCAAGACTGGCGACAGAGTTGTGGCGATTAATGGAAAGGAAGTCTCCGCCTGGGAAGATGTTGTCGATATGGTGCGTTC
AAATCCCGGGCACACACTCTCGGTTGAGGTGATGCGGGATGACCGGGAGCTTGCTATGTCATTACAACCGGAAACCGTAT
CCGAGGGTCACGCTGAAATTGGCAAGGCTGGAATTACGCCTGAAATCCATCATGAGATACTGGAAAATCTGCTGGTGAAA
ACCAGCTATCCTCCGATGGCAGCTTTGGTTAAAGCAGCTACCAAGACTTGGGAAATGTCTTATTTTACCGTGCGCATGCT
TGGGAAAATGGTCACTGGTGATGTTTCTCTGAAGAATATCAGCGGGCCGATTACCATTGCAAACTATGCCGGCCAGTCGG
CACAAATAGGGTTTACTGCCTACCTGGGATTCCTGGCCCTGATCAGTATCAGTCTTGGTGTGTTGAATCTTCTGCCGATT
CCGGTTCTGGATGGCGGACACTTGATGTATTACTTGATCGAGGTGGTGCGAGGTATACCATTATCTGAAAGAGTAATGTA
TATCGGCAATCAGATTGGTATGGCTTTGCTAATTACACTGATGATGTTTGCAATATATAACGATCTACTTCGCCTGGCTT
CTGAATAG

Upstream 100 bases:

>100_bases
TCGCAAGTGGTTGGATACTCAGGCTTGGCAAAGAGGACAGTCCGGAGCTCCGTTATTTCGTGCCGAGCAGTGGAATGGAT
AATTTTTGCAGATCTTTAAT

Downstream 100 bases:

>100_bases
ACATGAAATTCAGGTTTTATGCATTATTTTTTTTCCTGTATTCAATAGGCTGTGCGGCAAATGATTCATTCGTGGTCAAG
GATATCCGGGTGGAGGGTAT

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MTLLSTIFAFVIALGLLITFHEFGHYLVARWCGVKVLRFSLGFGQPLFKKRLGNDQTEWVVAAIPLGGYVKMLDEREGRV
PADELPRAFNRQPVSKRFAIVVAGPVANFLLAILLYWLLFILGVSGVKPILGEIEPATLAASAGFRNGDTITGIGDQAIT
TWQEARLLLLDNAVDKNPDVRITVTGESGISRQLKLDMSSLGAEDLESDFLNRLGLSVYRPIVAPVIDQVMVGGAAERAG
LKTGDRVVAINGKEVSAWEDVVDMVRSNPGHTLSVEVMRDDRELAMSLQPETVSEGHAEIGKAGITPEIHHEILENLLVK
TSYPPMAALVKAATKTWEMSYFTVRMLGKMVTGDVSLKNISGPITIANYAGQSAQIGFTAYLGFLALISISLGVLNLLPI
PVLDGGHLMYYLIEVVRGIPLSERVMYIGNQIGMALLITLMMFAIYNDLLRLASE

Sequences:

>Translated_455_residues
MTLLSTIFAFVIALGLLITFHEFGHYLVARWCGVKVLRFSLGFGQPLFKKRLGNDQTEWVVAAIPLGGYVKMLDEREGRV
PADELPRAFNRQPVSKRFAIVVAGPVANFLLAILLYWLLFILGVSGVKPILGEIEPATLAASAGFRNGDTITGIGDQAIT
TWQEARLLLLDNAVDKNPDVRITVTGESGISRQLKLDMSSLGAEDLESDFLNRLGLSVYRPIVAPVIDQVMVGGAAERAG
LKTGDRVVAINGKEVSAWEDVVDMVRSNPGHTLSVEVMRDDRELAMSLQPETVSEGHAEIGKAGITPEIHHEILENLLVK
TSYPPMAALVKAATKTWEMSYFTVRMLGKMVTGDVSLKNISGPITIANYAGQSAQIGFTAYLGFLALISISLGVLNLLPI
PVLDGGHLMYYLIEVVRGIPLSERVMYIGNQIGMALLITLMMFAIYNDLLRLASE
>Mature_454_residues
TLLSTIFAFVIALGLLITFHEFGHYLVARWCGVKVLRFSLGFGQPLFKKRLGNDQTEWVVAAIPLGGYVKMLDEREGRVP
ADELPRAFNRQPVSKRFAIVVAGPVANFLLAILLYWLLFILGVSGVKPILGEIEPATLAASAGFRNGDTITGIGDQAITT
WQEARLLLLDNAVDKNPDVRITVTGESGISRQLKLDMSSLGAEDLESDFLNRLGLSVYRPIVAPVIDQVMVGGAAERAGL
KTGDRVVAINGKEVSAWEDVVDMVRSNPGHTLSVEVMRDDRELAMSLQPETVSEGHAEIGKAGITPEIHHEILENLLVKT
SYPPMAALVKAATKTWEMSYFTVRMLGKMVTGDVSLKNISGPITIANYAGQSAQIGFTAYLGFLALISISLGVLNLLPIP
VLDGGHLMYYLIEVVRGIPLSERVMYIGNQIGMALLITLMMFAIYNDLLRLASE

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=454, Percent_Identity=44.273127753304, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49567; Mature: 49436

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLSTIFAFVIALGLLITFHEFGHYLVARWCGVKVLRFSLGFGQPLFKKRLGNDQTEWV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEE
VAAIPLGGYVKMLDEREGRVPADELPRAFNRQPVSKRFAIVVAGPVANFLLAILLYWLLF
EEEECCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHH
ILGVSGVKPILGEIEPATLAASAGFRNGDTITGIGDQAITTWQEARLLLLDNAVDKNPDV
HHCCCCCCHHHCCCCCHHHHHHCCCCCCCEEECCCCHHHHHHHHCEEEEEECCCCCCCCE
RITVTGESGISRQLKLDMSSLGAEDLESDFLNRLGLSVYRPIVAPVIDQVMVGGAAERAG
EEEEECCCCCCHHEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
LKTGDRVVAINGKEVSAWEDVVDMVRSNPGHTLSVEVMRDDRELAMSLQPETVSEGHAEI
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHCCCCCHHHCCHHHH
GKAGITPEIHHEILENLLVKTSYPPMAALVKAATKTWEMSYFTVRMLGKMVTGDVSLKNI
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
SGPITIANYAGQSAQIGFTAYLGFLALISISLGVLNLLPIPVLDGGHLMYYLIEVVRGIP
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHCCC
LSERVMYIGNQIGMALLITLMMFAIYNDLLRLASE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLLSTIFAFVIALGLLITFHEFGHYLVARWCGVKVLRFSLGFGQPLFKKRLGNDQTEWV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEE
VAAIPLGGYVKMLDEREGRVPADELPRAFNRQPVSKRFAIVVAGPVANFLLAILLYWLLF
EEEECCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHH
ILGVSGVKPILGEIEPATLAASAGFRNGDTITGIGDQAITTWQEARLLLLDNAVDKNPDV
HHCCCCCCHHHCCCCCHHHHHHCCCCCCCEEECCCCHHHHHHHHCEEEEEECCCCCCCCE
RITVTGESGISRQLKLDMSSLGAEDLESDFLNRLGLSVYRPIVAPVIDQVMVGGAAERAG
EEEEECCCCCCHHEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
LKTGDRVVAINGKEVSAWEDVVDMVRSNPGHTLSVEVMRDDRELAMSLQPETVSEGHAEI
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHCCCCCHHHCCHHHH
GKAGITPEIHHEILENLLVKTSYPPMAALVKAATKTWEMSYFTVRMLGKMVTGDVSLKNI
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
SGPITIANYAGQSAQIGFTAYLGFLALISISLGVLNLLPIPVLDGGHLMYYLIEVVRGIP
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHCCC
LSERVMYIGNQIGMALLITLMMFAIYNDLLRLASE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]