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The map label for this gene is macB [H]

Identifier: 114331978

GI number: 114331978

Start: 2127229

End: 2128452

Strand: Direct

Name: macB [H]

Synonym: Neut_2012

Alternate gene names: 114331978

Gene position: 2127229-2128452 (Clockwise)

Preceding gene: 114331977

Following gene: 114331979

Centisome position: 79.94

GC content: 52.78

Gene sequence:

>1224_bases
ATGAATTTACTGACCATCATCGGTGAAGCCATGCGGGCACTGCAGACCAACCGCCTGCGCACCGCCCTCACTATGCTTGG
CATGATCATCGGCGTAGCTGCAGTGGTACTCATGCTTGCCGTAGGACAAGGCGCACAAACCAGCATCAACAGTGCCATCG
CTTCAATGGGCAGCCATTTGCTGATCATCATGCCGGGTGCGACTTCTTCTGGCGGCGTGCGCTGGGGCATCGGCAGCGTT
AAAACGCTGACAGTGCAGGATGCGCAAGCCATTGCAGAATTACCCATGATTGATGCAACCGCCCCGATTATTTCGGGTGC
AGCACAACTTAACTACAATGCAAATAACTGGAGCACCATCTTGACAGGTGTTACGCCGGATTATTTTTCCATTAACAACT
GGGAAATTGCCAGCGGCACCATCTTTTCCGAAGGAGATTTACGCTCCGGCACACGTATGGCTGTTCTGGGACAGATCACC
GCAACCAGCCTGTTTGGTGATGAAGATCCGGTGGGAAAAGTCATCCGGATTACCAATCGGCCATTCACGGTTGTCGGTGT
ACTGGCTGCCAAAGGCCAAAGTTTGTCAGGACGCGATCAGGATGACAACGTATTCATTCCACTCACTACCGCGCAGCGAC
AGATCATTGGCAACCAGTTTCCCGGCTCCATCAATTTTATGATGGTTCGTGCAAAATCGGAGAACGACATGGAAGCTGCC
GAAGCAGAGATCACGCATCTGCTCCGTCAGCGCCACCGCATCAGCAACCACATGGAAAATGATTTTACTGTTCGCAACCT
GACCGCACTGGCCTCTGTAGCAAGCAACACCGCCAAGATCATGGGTTGGATGCTGGGCGCAATTGCATCCGTCTCACTAC
TGGTAGGTGGGATCGGCATCATGAATATCATGCTGGTCTCCGTTACAGAACGTACTCGTGAAATTGGAATACGCATGGCA
ATAGGAGCCAATCAGCGCATGATTCTTACCCAATTCCTGCTGGAATCACTGATGATCTGTACGTTAGGCGGGCTGACTGG
TATCGCCCTGGGAATTGGTGGCGCGTGGCTCGCCAGTCAACTTGCCGGGATTGACATTGTCATTACATCCGGGACAATTG
CTCTGGCCTTCTCATTTGCCTCCATCACCGGTATTTTCTTCGGCCTCTATCCCGCCCGGAAAGCCGCCGCACTCAAACCC
GTGGAAGCCTTACGCCACGAATAA

Upstream 100 bases:

>100_bases
ATATCGCTGCCTGGACACAGCGCCTGATCCGGCTCAAGGATGGACGCATCATTGAAGATCGTCCAATGGAAAAACTCGCT
GCCTCCCCCGCTGCCTCATC

Downstream 100 bases:

>100_bases
TCCCGGATTCTCTATCCGACTGGAAAACACGGGATGCAAATTGCCAGGAACGGAGCACGAGCTTTGGAAAAAATTTGATT
TGGATTATGTTCCCATAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNLLTIIGEAMRALQTNRLRTALTMLGMIIGVAAVVLMLAVGQGAQTSINSAIASMGSHLLIIMPGATSSGGVRWGIGSV
KTLTVQDAQAIAELPMIDATAPIISGAAQLNYNANNWSTILTGVTPDYFSINNWEIASGTIFSEGDLRSGTRMAVLGQIT
ATSLFGDEDPVGKVIRITNRPFTVVGVLAAKGQSLSGRDQDDNVFIPLTTAQRQIIGNQFPGSINFMMVRAKSENDMEAA
EAEITHLLRQRHRISNHMENDFTVRNLTALASVASNTAKIMGWMLGAIASVSLLVGGIGIMNIMLVSVTERTREIGIRMA
IGANQRMILTQFLLESLMICTLGGLTGIALGIGGAWLASQLAGIDIVITSGTIALAFSFASITGIFFGLYPARKAAALKP
VEALRHE

Sequences:

>Translated_407_residues
MNLLTIIGEAMRALQTNRLRTALTMLGMIIGVAAVVLMLAVGQGAQTSINSAIASMGSHLLIIMPGATSSGGVRWGIGSV
KTLTVQDAQAIAELPMIDATAPIISGAAQLNYNANNWSTILTGVTPDYFSINNWEIASGTIFSEGDLRSGTRMAVLGQIT
ATSLFGDEDPVGKVIRITNRPFTVVGVLAAKGQSLSGRDQDDNVFIPLTTAQRQIIGNQFPGSINFMMVRAKSENDMEAA
EAEITHLLRQRHRISNHMENDFTVRNLTALASVASNTAKIMGWMLGAIASVSLLVGGIGIMNIMLVSVTERTREIGIRMA
IGANQRMILTQFLLESLMICTLGGLTGIALGIGGAWLASQLAGIDIVITSGTIALAFSFASITGIFFGLYPARKAAALKP
VEALRHE
>Mature_407_residues
MNLLTIIGEAMRALQTNRLRTALTMLGMIIGVAAVVLMLAVGQGAQTSINSAIASMGSHLLIIMPGATSSGGVRWGIGSV
KTLTVQDAQAIAELPMIDATAPIISGAAQLNYNANNWSTILTGVTPDYFSINNWEIASGTIFSEGDLRSGTRMAVLGQIT
ATSLFGDEDPVGKVIRITNRPFTVVGVLAAKGQSLSGRDQDDNVFIPLTTAQRQIIGNQFPGSINFMMVRAKSENDMEAA
EAEITHLLRQRHRISNHMENDFTVRNLTALASVASNTAKIMGWMLGAIASVSLLVGGIGIMNIMLVSVTERTREIGIRMA
IGANQRMILTQFLLESLMICTLGGLTGIALGIGGAWLASQLAGIDIVITSGTIALAFSFASITGIFFGLYPARKAAALKP
VEALRHE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=400, Percent_Identity=37.25, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43073; Mature: 43073

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLTIIGEAMRALQTNRLRTALTMLGMIIGVAAVVLMLAVGQGAQTSINSAIASMGSHL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCE
LIIMPGATSSGGVRWGIGSVKTLTVQDAQAIAELPMIDATAPIISGAAQLNYNANNWSTI
EEEECCCCCCCCEEECCCCEEEEEEHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCCEEE
LTGVTPDYFSINNWEIASGTIFSEGDLRSGTRMAVLGQITATSLFGDEDPVGKVIRITNR
EECCCCCCEECCCEEEECCEEECCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCEEEECCC
PFTVVGVLAAKGQSLSGRDQDDNVFIPLTTAQRQIIGNQFPGSINFMMVRAKSENDMEAA
CEEEEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCEEEEEEEECCCCCHHHH
EAEITHLLRQRHRISNHMENDFTVRNLTALASVASNTAKIMGWMLGAIASVSLLVGGIGI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIMLVSVTERTREIGIRMAIGANQRMILTQFLLESLMICTLGGLTGIALGIGGAWLASQ
HHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHH
LAGIDIVITSGTIALAFSFASITGIFFGLYPARKAAALKPVEALRHE
HCCEEEEEECCCEEEHHHHHHHHHHHHHHCCHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MNLLTIIGEAMRALQTNRLRTALTMLGMIIGVAAVVLMLAVGQGAQTSINSAIASMGSHL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCE
LIIMPGATSSGGVRWGIGSVKTLTVQDAQAIAELPMIDATAPIISGAAQLNYNANNWSTI
EEEECCCCCCCCEEECCCCEEEEEEHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCCEEE
LTGVTPDYFSINNWEIASGTIFSEGDLRSGTRMAVLGQITATSLFGDEDPVGKVIRITNR
EECCCCCCEECCCEEEECCEEECCCCCCCCCEEEEEEEHHHHHHCCCCCCCCCEEEECCC
PFTVVGVLAAKGQSLSGRDQDDNVFIPLTTAQRQIIGNQFPGSINFMMVRAKSENDMEAA
CEEEEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCEEEEEEEECCCCCHHHH
EAEITHLLRQRHRISNHMENDFTVRNLTALASVASNTAKIMGWMLGAIASVSLLVGGIGI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIMLVSVTERTREIGIRMAIGANQRMILTQFLLESLMICTLGGLTGIALGIGGAWLASQ
HHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHH
LAGIDIVITSGTIALAFSFASITGIFFGLYPARKAAALKPVEALRHE
HCCEEEEEECCCEEEHHHHHHHHHHHHHHCCHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA