Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 114331973

GI number: 114331973

Start: 2120536

End: 2121915

Strand: Direct

Name: pgm [H]

Synonym: Neut_2007

Alternate gene names: 114331973

Gene position: 2120536-2121915 (Clockwise)

Preceding gene: 114331972

Following gene: 114331974

Centisome position: 79.69

GC content: 52.54

Gene sequence:

>1380_bases
ATGAATACACTTCCACGCCGCGAAATCTTCAAGGCTTACGACATACGTGGCATCGTAGAAACCGCACTGACTCCGGAAGT
AGTGGAACAAATCGGCCATGCCATTGGTTCCGAAGCACGCGCACGTCAGCTGACAGCTATTGCAGTGGGTCGCGATGGCC
GTTTATCCGGTCCTCAACTGGTGCAAGCCTTGACGAACGGTATCCGTAAAAGTGGAATTGATGTCATCGATATTGGCATG
GTCGCCACCCCGGTGCTGTATTACGCTGCTCACGAACTCTGTCATTATTCTGGGGTAATGGTAACCGGCAGCCACAATCC
GCCAGAATATAACGGTCTCAAGATCGTGCTGGGAGGCGAAACGCTGGCAGCCGAGACCATTCAATCATTACGGTTGCGTA
TTGAGCAAAATAACCTGACGCATGGACAAGGCGGTTATCGCCAACACGACATCATCCCCGCCTATTTGCAACGCATCGTG
GAGGATGTCAAGCTGGCTCGGCCAATCAAAATCGTGGTGGACTGCGGCAATGGCGTAACTGGCATTCTGGCGCCAGAACT
GTATCGCCGCCTGGGCTGCGAAGTAATCGAGCTGTTTTGTGAAGTGGATGGTACTTTCCCGAATCATCATCCCGATCCTT
CAGTCCCGGAGAATTTGCAGGATGTCATCCGCACACTTGCTACTACCGATGCTGAAATTGGTTTTGCCTTTGATGGCGAT
GGTGACCGGCTGGGCGTCGTCACCAAGGATGGAAGCATCATTTTCCCGGATCGCCAACTTATGCTGTTTGCTGCCGATGT
GTTGTCCAGAAACCCTGGCGGCCAGATCATCTACGATGTCAAATGCACACGCACACTGGCACCGTGGATCACACAACATG
GCGGCAAACCCATCATGTGGAAAACGGGGCACTCCTTCATTAAGGCCAAGTTAAAGGAAACAGGCGCACTCCTGGCAGGC
GAGATGAGCGGCCATATCTTTTTCCAGGAACGTTGGTACGGATTCGACGATGGCCTATACGCAGGTGCGCGTCTGCTGGA
ATTATTGAGTAAACAAACCGATCCGGAAGCGGTGCTGCATGCCCTGCCTGATACGATCAACACACCTGAATTGCAGATCA
GACTCAAGGAAGGAGAAAATCACGCCTTGATTGCGCAACTTCAGCAGGAGGCAAACTTCCCTGAGGCGGATCAGGTGATT
ACGATTGACGGGCTGCGGGTGGAATACAAGGATGGATTCGGCCTGATCCGGGCATCCAATACCACTCCGGTCGCAGTACT
ACGTTTCGAGGCTGACAATCAGGATGCGCTGAAACGTATCCAGCAAGATTTTCGCCAAATCATTCTGCAAGCCAGGCCGG
ATGCAAATCTGCCTTTCTAA

Upstream 100 bases:

>100_bases
CCTGATCGGCACACCGAATCCGGATCATCACGGGTAACACGGGCAAAAGACTGGCTTTCGTATCATTCATTATTTATCCG
GATCAAGGAATCATCACTGC

Downstream 100 bases:

>100_bases
CCGGGTTCCAGTTACGGACCCGAATACCCTTCCACAATGAAGATCGCGCTTGCCCAGATCAACTGCATGGCAGGCGATTT
GAACGGTAACCCGCTTAAAA

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNTLPRREIFKAYDIRGIVETALTPEVVEQIGHAIGSEARARQLTAIAVGRDGRLSGPQLVQALTNGIRKSGIDVIDIGM
VATPVLYYAAHELCHYSGVMVTGSHNPPEYNGLKIVLGGETLAAETIQSLRLRIEQNNLTHGQGGYRQHDIIPAYLQRIV
EDVKLARPIKIVVDCGNGVTGILAPELYRRLGCEVIELFCEVDGTFPNHHPDPSVPENLQDVIRTLATTDAEIGFAFDGD
GDRLGVVTKDGSIIFPDRQLMLFAADVLSRNPGGQIIYDVKCTRTLAPWITQHGGKPIMWKTGHSFIKAKLKETGALLAG
EMSGHIFFQERWYGFDDGLYAGARLLELLSKQTDPEAVLHALPDTINTPELQIRLKEGENHALIAQLQQEANFPEADQVI
TIDGLRVEYKDGFGLIRASNTTPVAVLRFEADNQDALKRIQQDFRQIILQARPDANLPF

Sequences:

>Translated_459_residues
MNTLPRREIFKAYDIRGIVETALTPEVVEQIGHAIGSEARARQLTAIAVGRDGRLSGPQLVQALTNGIRKSGIDVIDIGM
VATPVLYYAAHELCHYSGVMVTGSHNPPEYNGLKIVLGGETLAAETIQSLRLRIEQNNLTHGQGGYRQHDIIPAYLQRIV
EDVKLARPIKIVVDCGNGVTGILAPELYRRLGCEVIELFCEVDGTFPNHHPDPSVPENLQDVIRTLATTDAEIGFAFDGD
GDRLGVVTKDGSIIFPDRQLMLFAADVLSRNPGGQIIYDVKCTRTLAPWITQHGGKPIMWKTGHSFIKAKLKETGALLAG
EMSGHIFFQERWYGFDDGLYAGARLLELLSKQTDPEAVLHALPDTINTPELQIRLKEGENHALIAQLQQEANFPEADQVI
TIDGLRVEYKDGFGLIRASNTTPVAVLRFEADNQDALKRIQQDFRQIILQARPDANLPF
>Mature_459_residues
MNTLPRREIFKAYDIRGIVETALTPEVVEQIGHAIGSEARARQLTAIAVGRDGRLSGPQLVQALTNGIRKSGIDVIDIGM
VATPVLYYAAHELCHYSGVMVTGSHNPPEYNGLKIVLGGETLAAETIQSLRLRIEQNNLTHGQGGYRQHDIIPAYLQRIV
EDVKLARPIKIVVDCGNGVTGILAPELYRRLGCEVIELFCEVDGTFPNHHPDPSVPENLQDVIRTLATTDAEIGFAFDGD
GDRLGVVTKDGSIIFPDRQLMLFAADVLSRNPGGQIIYDVKCTRTLAPWITQHGGKPIMWKTGHSFIKAKLKETGALLAG
EMSGHIFFQERWYGFDDGLYAGARLLELLSKQTDPEAVLHALPDTINTPELQIRLKEGENHALIAQLQQEANFPEADQVI
TIDGLRVEYKDGFGLIRASNTTPVAVLRFEADNQDALKRIQQDFRQIILQARPDANLPF

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=32.8767123287671, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789566, Length=359, Percent_Identity=28.4122562674095, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 50635; Mature: 50635

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLPRREIFKAYDIRGIVETALTPEVVEQIGHAIGSEARARQLTAIAVGRDGRLSGPQL
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHEEEEEEECCCCCCCCHHH
VQALTNGIRKSGIDVIDIGMVATPVLYYAAHELCHYSGVMVTGSHNPPEYNGLKIVLGGE
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCC
TLAAETIQSLRLRIEQNNLTHGQGGYRQHDIIPAYLQRIVEDVKLARPIKIVVDCGNGVT
HHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCC
GILAPELYRRLGCEVIELFCEVDGTFPNHHPDPSVPENLQDVIRTLATTDAEIGFAFDGD
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCC
GDRLGVVTKDGSIIFPDRQLMLFAADVLSRNPGGQIIYDVKCTRTLAPWITQHGGKPIMW
CCEEEEEECCCCEECCCCHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHCCCCEEEE
KTGHSFIKAKLKETGALLAGEMSGHIFFQERWYGFDDGLYAGARLLELLSKQTDPEAVLH
CCCHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
ALPDTINTPELQIRLKEGENHALIAQLQQEANFPEADQVITIDGLRVEYKDGFGLIRASN
HCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEECCEEEEECCCCEEEEECC
TTPVAVLRFEADNQDALKRIQQDFRQIILQARPDANLPF
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNTLPRREIFKAYDIRGIVETALTPEVVEQIGHAIGSEARARQLTAIAVGRDGRLSGPQL
CCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHEEEEEEECCCCCCCCHHH
VQALTNGIRKSGIDVIDIGMVATPVLYYAAHELCHYSGVMVTGSHNPPEYNGLKIVLGGE
HHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCC
TLAAETIQSLRLRIEQNNLTHGQGGYRQHDIIPAYLQRIVEDVKLARPIKIVVDCGNGVT
HHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCC
GILAPELYRRLGCEVIELFCEVDGTFPNHHPDPSVPENLQDVIRTLATTDAEIGFAFDGD
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCC
GDRLGVVTKDGSIIFPDRQLMLFAADVLSRNPGGQIIYDVKCTRTLAPWITQHGGKPIMW
CCEEEEEECCCCEECCCCHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHCCCCEEEE
KTGHSFIKAKLKETGALLAGEMSGHIFFQERWYGFDDGLYAGARLLELLSKQTDPEAVLH
CCCHHHHHHHHHHCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
ALPDTINTPELQIRLKEGENHALIAQLQQEANFPEADQVITIDGLRVEYKDGFGLIRASN
HCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCCEEEECCEEEEECCCCEEEEECC
TTPVAVLRFEADNQDALKRIQQDFRQIILQARPDANLPF
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]