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The map label for this gene is nagZ

Identifier: 114331751

GI number: 114331751

Start: 1880088

End: 1881134

Strand: Reverse

Name: nagZ

Synonym: Neut_1774

Alternate gene names: 114331751

Gene position: 1881134-1880088 (Counterclockwise)

Preceding gene: 114331752

Following gene: 114331750

Centisome position: 70.69

GC content: 49.28

Gene sequence:

>1047_bases
ATGTTTCTTGGCCCGCTGATGCTCGACATAGCGGGCACAACGTTAACTGAAACGGATCGTGTTCAATTGAGTCATCCGCT
TGTTGGTGGCGTTATTCTGTTTGCACGAAATTATGAATCACCAGCACAGCTATCCGAATTAACCGCATCCATTCATGCAT
TGCGCTCTCCGCCTCTATTGATTGCTGTAGATCAGGAAGGTGGCAGGGTACAGCGTTTCCGTGACGGTTTTACGCGTTTG
CCGCCAATGCGTACGCTGGGAGAAATCCAGGACAGGAATCCAGATTTGTCGCTTCATCTGGCTCGGCAGATTGGTTATGT
ACTGGCTGCAGAGCTCAAGGCTTGTGGGGTTGATGTGAGTTTTACACCTGTGCTCGATCTTGATTGCGAGCAGAGTAGCG
TGATTGGTGATCGTGCTTTTTATCGTGAGCCACAAGTTGTTGCTGAACTGGCTCATGCCTTGATGAGCGGTTTGCAGTCG
GTGGGAATGGTGGCAGTAGGTAAACATTTCCCTGGTCATGGTGCGATCCAGGCGGATACCCATGTTGAAACTGCTATTGA
TTCTCGCAATTACACGGATATTGAAAAGAAAGATCTGACCCCTTTCCGCCGGATGATTGATACAGGGCTTTCCGGCATCA
TGGCTGCGCATGTTATTTATCCAGCCATTGATCCAAACCCGGCAGGTTTTTCCAGCAAGTGGTTGCAGGATATTTTGCGG
AACGAGCTGGGATTTAGGGGTTGCATTTTCAGTGATGACCTGTGTATGCAGGCTGCCAGAAATTATGGCAGCATCACTCA
CCGGGCAGAGCAAGCCTTGCAGGCAGGGTGTAACATGGTATTGATATGTAACGATCCCGATTCAGCAGACGAATTGTTGA
CATCCCTGCAATGGGAATTTTCTGCTGTCGATACAGCCAGGCTGGAACATATGCGTGGGCAGCAAACAGTTCATTCGATG
GCGCAGTTGCATGAAATGGAGCGATTCATTCGGGCGACTGAAGAGATCAGCAGAATCAGTCTGGCTAATATCAGTGTATC
CGTGTGA

Upstream 100 bases:

>100_bases
TGATCGATTGGATAGGGCAGCGCGGTATTGTTAGTCATCATCTTTCCATTAGTGATGAATTGACACTGGCAAGTGCCTTT
GTGGTGCTGGAAAAATAAAT

Downstream 100 bases:

>100_bases
GAATTGCATTTTTAGCGTTCCGGGGTAATTCAGACCGGATTTCTCAACGAGCAATTTTTGTCACTTAATTGATATGAATA
ATATATTCGATGTAGCAGTT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MFLGPLMLDIAGTTLTETDRVQLSHPLVGGVILFARNYESPAQLSELTASIHALRSPPLLIAVDQEGGRVQRFRDGFTRL
PPMRTLGEIQDRNPDLSLHLARQIGYVLAAELKACGVDVSFTPVLDLDCEQSSVIGDRAFYREPQVVAELAHALMSGLQS
VGMVAVGKHFPGHGAIQADTHVETAIDSRNYTDIEKKDLTPFRRMIDTGLSGIMAAHVIYPAIDPNPAGFSSKWLQDILR
NELGFRGCIFSDDLCMQAARNYGSITHRAEQALQAGCNMVLICNDPDSADELLTSLQWEFSAVDTARLEHMRGQQTVHSM
AQLHEMERFIRATEEISRISLANISVSV

Sequences:

>Translated_348_residues
MFLGPLMLDIAGTTLTETDRVQLSHPLVGGVILFARNYESPAQLSELTASIHALRSPPLLIAVDQEGGRVQRFRDGFTRL
PPMRTLGEIQDRNPDLSLHLARQIGYVLAAELKACGVDVSFTPVLDLDCEQSSVIGDRAFYREPQVVAELAHALMSGLQS
VGMVAVGKHFPGHGAIQADTHVETAIDSRNYTDIEKKDLTPFRRMIDTGLSGIMAAHVIYPAIDPNPAGFSSKWLQDILR
NELGFRGCIFSDDLCMQAARNYGSITHRAEQALQAGCNMVLICNDPDSADELLTSLQWEFSAVDTARLEHMRGQQTVHSM
AQLHEMERFIRATEEISRISLANISVSV
>Mature_348_residues
MFLGPLMLDIAGTTLTETDRVQLSHPLVGGVILFARNYESPAQLSELTASIHALRSPPLLIAVDQEGGRVQRFRDGFTRL
PPMRTLGEIQDRNPDLSLHLARQIGYVLAAELKACGVDVSFTPVLDLDCEQSSVIGDRAFYREPQVVAELAHALMSGLQS
VGMVAVGKHFPGHGAIQADTHVETAIDSRNYTDIEKKDLTPFRRMIDTGLSGIMAAHVIYPAIDPNPAGFSSKWLQDILR
NELGFRGCIFSDDLCMQAARNYGSITHRAEQALQAGCNMVLICNDPDSADELLTSLQWEFSAVDTARLEHMRGQQTVHSM
AQLHEMERFIRATEEISRISLANISVSV

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily

Homologues:

Organism=Escherichia coli, GI1787350, Length=309, Percent_Identity=45.6310679611651, Blast_Score=274, Evalue=6e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NAGZ_NITEC (Q0AF74)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747973.1
- ProteinModelPortal:   Q0AF74
- STRING:   Q0AF74
- GeneID:   4273123
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1774
- NMPDR:   fig|335283.3.peg.2011
- eggNOG:   COG1472
- HOGENOM:   HBG617255
- OMA:   DLTMEGA
- PhylomeDB:   Q0AF74
- ProtClustDB:   PRK05337
- BioCyc:   NEUT335283:NEUT_1774-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00364
- InterPro:   IPR022956
- InterPro:   IPR001764
- InterPro:   IPR017853
- Gene3D:   G3DSA:3.20.20.300

Pfam domain/function: PF00933 Glyco_hydro_3; SSF51445 Glyco_hydro_cat

EC number: =3.2.1.52

Molecular weight: Translated: 38310; Mature: 38310

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: ACT_SITE 252-252

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLGPLMLDIAGTTLTETDRVQLSHPLVGGVILFARNYESPAQLSELTASIHALRSPPLL
CCCCHHHHHHCCCCCCCCCCEEECCCHHCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEE
IAVDQEGGRVQRFRDGFTRLPPMRTLGEIQDRNPDLSLHLARQIGYVLAAELKACGVDVS
EEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
FTPVLDLDCEQSSVIGDRAFYREPQVVAELAHALMSGLQSVGMVAVGKHFPGHGAIQADT
ECEEEECCCCCHHHHCCHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECC
HVETAIDSRNYTDIEKKDLTPFRRMIDTGLSGIMAAHVIYPAIDPNPAGFSSKWLQDILR
HHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
NELGFRGCIFSDDLCMQAARNYGSITHRAEQALQAGCNMVLICNDPDSADELLTSLQWEF
HHCCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
SAVDTARLEHMRGQQTVHSMAQLHEMERFIRATEEISRISLANISVSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEC
>Mature Secondary Structure
MFLGPLMLDIAGTTLTETDRVQLSHPLVGGVILFARNYESPAQLSELTASIHALRSPPLL
CCCCHHHHHHCCCCCCCCCCEEECCCHHCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEE
IAVDQEGGRVQRFRDGFTRLPPMRTLGEIQDRNPDLSLHLARQIGYVLAAELKACGVDVS
EEECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCE
FTPVLDLDCEQSSVIGDRAFYREPQVVAELAHALMSGLQSVGMVAVGKHFPGHGAIQADT
ECEEEECCCCCHHHHCCHHHHCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEECC
HVETAIDSRNYTDIEKKDLTPFRRMIDTGLSGIMAAHVIYPAIDPNPAGFSSKWLQDILR
HHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
NELGFRGCIFSDDLCMQAARNYGSITHRAEQALQAGCNMVLICNDPDSADELLTSLQWEF
HHCCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHH
SAVDTARLEHMRGQQTVHSMAQLHEMERFIRATEEISRISLANISVSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA