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The map label for this gene is yfnA [H]

Identifier: 114331224

GI number: 114331224

Start: 1283338

End: 1284897

Strand: Reverse

Name: yfnA [H]

Synonym: Neut_1227

Alternate gene names: 114331224

Gene position: 1284897-1283338 (Counterclockwise)

Preceding gene: 114331225

Following gene: 114331223

Centisome position: 48.29

GC content: 49.23

Gene sequence:

>1560_bases
ATGATCTTCTGGCGTATAAAATCGCTGGACTCTATGCTGGCCACGGCTGCCAAGAAAAGTCTTCATCGTTCCCTGGGCGT
GTGGCAGCTGACCTTGCTGGGAATCGGCGCAATTATAGGAACCGGTATTTTTGTACTAACTGCCGAAGCCGCCCAGAAAG
CCGGCCCCGGAATGATGATCGCTTTCGTCATTGCCGGTTTTGTCTGTGCAGTGGCTGCGCTTTGCTATTCTGAGCTCTCT
TCGATGGTACCGATATCCGGATCTGCCTATACCTATTCCTACGCAGTACTGGGTGAATTAATCGCCTGGATGGTGGGTTG
GGCATTGATCCTGGAATATTCTGTTGCTGCTGGTGCGGTGGCCGTAGGTTGGTCAGGCTATTTCGTCGGATTATTGAATT
CCTCGCTGGGGATTAAAATTCCCTTTGCTCTGGTAAATGGCCCCTTTGCCGGGGGAATCATCAATCTGCCTGCAGTAATC
ATTTGCATCCTGGTTGTCAGTTTGTTAATCATCGGCACACGGGAAAGCGCTACATTCAATGCTACTCTTGTTGCGGTCAA
AATTGTCGCTCTGACAGCATTTATAGCACTTGCTTTGCCGGTTGCTGATATGAATCACTTTGATCCTTTTCTGCCATTAG
GAACATCAGGTGTTGCCGCTGCAGCGGCATCCATTTTTTTTGCGTATGTCGGTTTCGATGCGGTATCGACTGCGGCGGAA
GAAACCAAAGATCCACAACGAAATCTTCCGATTGCCCTGATCAGCTCATTGTTGATTTGTACATTATTTTATTTACTGAT
TTCCGCTGGTGTGGTCGGTGCGGTAGGTGCGCAGCCATTAATTGATGCCACAGGGGAAGGTCTTATGCCCGGTTCCAGGG
AAATGGCAGCGCAATGCAAATTGCTCGCAGCAGTGGGACAACAACCGGTTGTCTGTTCGCATGAAGCGCTGGCACATGTG
CTACGCCAGATCGGATGGGAGAAAGTTGGCAACCTGATCGGTCTGGCAGCTTTCCTGGCGCTTCCTTCAGTCATCCTCAT
GATGCTGTTTGGGCAGACGCGTATTTTCTTCGTCATGTCGCGTGATGGCCTGCTCCCGGAAGTATTAAGCCATATTCATC
CGCGTTTCAAAACCCCGTATATCGTGACACTGGTTACCGGGCTCGTCGTTACGGCATCAGCCGCTTTCCTGCCAGTAGGC
AAGCTAGCGAATATCTCCAATTCCGGAACGCTGTTTGCTTTTCTAGTGGTAGCGCTATCCGTCATGATTCTTCGGATCAA
GGATAAGAATCGTGCAAGACCTTTTAAAGCACCTGTAATCTGGCTGGTAGGACCACTTGCTATCGGCGGCTGCATAACAC
TTTTTTTGTTTCTGCCAACAGATGCCCAACTGGTATTTCCAATCTGGACAGGAGTTGGGCTGATTTTTTATTTTCTGTAT
GGCTATCGCAGAAGTCATGTTCTGCTGGGTATTAGTACTCCCCCTGGTGGCGAAAATTTGATTGAACCAATCCGATCTCT
CGTGAATCACGAAGAAGGAGAACGAGACAAGGAAAAGTAA

Upstream 100 bases:

>100_bases
ATCTCGATTTCGGGTTTTTGGTCATGGCATTTCTTGTACACTACCTCGCATTGAATTCAGAAATGTTGCAACTACCTGTT
TTTATTGAAGGAGGAAGCTC

Downstream 100 bases:

>100_bases
CCTCCTGCCATAATTCTGATGCTCAATCGGAACATAAGGCATGAGAAACTTATGCCGTGCGGTCCGGGATGATCGATTCA
ATCACCTGCTGAAAATAGCC

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MIFWRIKSLDSMLATAAKKSLHRSLGVWQLTLLGIGAIIGTGIFVLTAEAAQKAGPGMMIAFVIAGFVCAVAALCYSELS
SMVPISGSAYTYSYAVLGELIAWMVGWALILEYSVAAGAVAVGWSGYFVGLLNSSLGIKIPFALVNGPFAGGIINLPAVI
ICILVVSLLIIGTRESATFNATLVAVKIVALTAFIALALPVADMNHFDPFLPLGTSGVAAAAASIFFAYVGFDAVSTAAE
ETKDPQRNLPIALISSLLICTLFYLLISAGVVGAVGAQPLIDATGEGLMPGSREMAAQCKLLAAVGQQPVVCSHEALAHV
LRQIGWEKVGNLIGLAAFLALPSVILMMLFGQTRIFFVMSRDGLLPEVLSHIHPRFKTPYIVTLVTGLVVTASAAFLPVG
KLANISNSGTLFAFLVVALSVMILRIKDKNRARPFKAPVIWLVGPLAIGGCITLFLFLPTDAQLVFPIWTGVGLIFYFLY
GYRRSHVLLGISTPPGGENLIEPIRSLVNHEEGERDKEK

Sequences:

>Translated_519_residues
MIFWRIKSLDSMLATAAKKSLHRSLGVWQLTLLGIGAIIGTGIFVLTAEAAQKAGPGMMIAFVIAGFVCAVAALCYSELS
SMVPISGSAYTYSYAVLGELIAWMVGWALILEYSVAAGAVAVGWSGYFVGLLNSSLGIKIPFALVNGPFAGGIINLPAVI
ICILVVSLLIIGTRESATFNATLVAVKIVALTAFIALALPVADMNHFDPFLPLGTSGVAAAAASIFFAYVGFDAVSTAAE
ETKDPQRNLPIALISSLLICTLFYLLISAGVVGAVGAQPLIDATGEGLMPGSREMAAQCKLLAAVGQQPVVCSHEALAHV
LRQIGWEKVGNLIGLAAFLALPSVILMMLFGQTRIFFVMSRDGLLPEVLSHIHPRFKTPYIVTLVTGLVVTASAAFLPVG
KLANISNSGTLFAFLVVALSVMILRIKDKNRARPFKAPVIWLVGPLAIGGCITLFLFLPTDAQLVFPIWTGVGLIFYFLY
GYRRSHVLLGISTPPGGENLIEPIRSLVNHEEGERDKEK
>Mature_519_residues
MIFWRIKSLDSMLATAAKKSLHRSLGVWQLTLLGIGAIIGTGIFVLTAEAAQKAGPGMMIAFVIAGFVCAVAALCYSELS
SMVPISGSAYTYSYAVLGELIAWMVGWALILEYSVAAGAVAVGWSGYFVGLLNSSLGIKIPFALVNGPFAGGIINLPAVI
ICILVVSLLIIGTRESATFNATLVAVKIVALTAFIALALPVADMNHFDPFLPLGTSGVAAAAASIFFAYVGFDAVSTAAE
ETKDPQRNLPIALISSLLICTLFYLLISAGVVGAVGAQPLIDATGEGLMPGSREMAAQCKLLAAVGQQPVVCSHEALAHV
LRQIGWEKVGNLIGLAAFLALPSVILMMLFGQTRIFFVMSRDGLLPEVLSHIHPRFKTPYIVTLVTGLVVTASAAFLPVG
KLANISNSGTLFAFLVVALSVMILRIKDKNRARPFKAPVIWLVGPLAIGGCITLFLFLPTDAQLVFPIWTGVGLIFYFLY
GYRRSHVLLGISTPPGGENLIEPIRSLVNHEEGERDKEK

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=464, Percent_Identity=29.9568965517241, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI258614003, Length=476, Percent_Identity=30.8823529411765, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI258614005, Length=476, Percent_Identity=30.8823529411765, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI114326544, Length=458, Percent_Identity=29.4759825327511, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI114326550, Length=458, Percent_Identity=29.4759825327511, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI110347453, Length=431, Percent_Identity=31.7865429234339, Blast_Score=185, Evalue=1e-46,
Organism=Homo sapiens, GI258645169, Length=476, Percent_Identity=30.672268907563, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI181337167, Length=445, Percent_Identity=28.314606741573, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI115648063, Length=533, Percent_Identity=25.515947467167, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI115648022, Length=533, Percent_Identity=25.515947467167, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI187423910, Length=515, Percent_Identity=24.0776699029126, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI7657591, Length=515, Percent_Identity=24.0776699029126, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI71979932, Length=432, Percent_Identity=27.5462962962963, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI33286428, Length=448, Percent_Identity=24.3303571428571, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI186910308, Length=483, Percent_Identity=24.8447204968944, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI186910306, Length=483, Percent_Identity=24.8447204968944, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI186910304, Length=483, Percent_Identity=24.8447204968944, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI7657683, Length=394, Percent_Identity=23.6040609137056, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI87081869, Length=517, Percent_Identity=23.7911025145068, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082250, Length=490, Percent_Identity=22.2448979591837, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789017, Length=401, Percent_Identity=23.6907730673317, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786302, Length=415, Percent_Identity=25.0602409638554, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081708, Length=270, Percent_Identity=23.7037037037037, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081915, Length=398, Percent_Identity=24.8743718592965, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790653, Length=265, Percent_Identity=26.0377358490566, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786789, Length=267, Percent_Identity=23.9700374531835, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788480, Length=272, Percent_Identity=25.7352941176471, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=437, Percent_Identity=31.8077803203661, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17531343, Length=424, Percent_Identity=28.7735849056604, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17533459, Length=437, Percent_Identity=29.0617848970252, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17540018, Length=469, Percent_Identity=25.5863539445629, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17537453, Length=309, Percent_Identity=26.8608414239482, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566699, Length=409, Percent_Identity=26.6503667481663, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71995382, Length=293, Percent_Identity=23.2081911262799, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24667468, Length=435, Percent_Identity=32.4137931034483, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24668806, Length=454, Percent_Identity=28.8546255506608, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI21356285, Length=454, Percent_Identity=28.8546255506608, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24668802, Length=454, Percent_Identity=28.8546255506608, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI221512776, Length=450, Percent_Identity=31.3333333333333, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24666159, Length=450, Percent_Identity=31.3333333333333, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI281366235, Length=443, Percent_Identity=30.4740406320542, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI116007820, Length=443, Percent_Identity=30.4740406320542, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI116007818, Length=452, Percent_Identity=31.1946902654867, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI85725152, Length=452, Percent_Identity=31.1946902654867, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI161077963, Length=432, Percent_Identity=28.9351851851852, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI221331183, Length=441, Percent_Identity=25.6235827664399, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17647653, Length=441, Percent_Identity=25.6235827664399, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24664379, Length=441, Percent_Identity=25.6235827664399, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357367, Length=383, Percent_Identity=23.7597911227154, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24651635, Length=414, Percent_Identity=22.9468599033816, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651633, Length=414, Percent_Identity=22.9468599033816, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641995, Length=431, Percent_Identity=23.6658932714617, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641993, Length=431, Percent_Identity=23.6658932714617, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45550968, Length=485, Percent_Identity=21.6494845360825, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921172, Length=485, Percent_Identity=21.6494845360825, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54977; Mature: 54977

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFWRIKSLDSMLATAAKKSLHRSLGVWQLTLLGIGAIIGTGIFVLTAEAAQKAGPGMMI
CEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEEEHHHHHCCCCHHH
AFVIAGFVCAVAALCYSELSSMVPISGSAYTYSYAVLGELIAWMVGWALILEYSVAAGAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
AVGWSGYFVGLLNSSLGIKIPFALVNGPFAGGIINLPAVIICILVVSLLIIGTRESATFN
EECCCHHHHHHHCCCCCCEEEHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ATLVAVKIVALTAFIALALPVADMNHFDPFLPLGTSGVAAAAASIFFAYVGFDAVSTAAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ETKDPQRNLPIALISSLLICTLFYLLISAGVVGAVGAQPLIDATGEGLMPGSREMAAQCK
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
LLAAVGQQPVVCSHEALAHVLRQIGWEKVGNLIGLAAFLALPSVILMMLFGQTRIFFVMS
HHHHCCCCCCEECHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
RDGLLPEVLSHIHPRFKTPYIVTLVTGLVVTASAAFLPVGKLANISNSGTLFAFLVVALS
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHH
VMILRIKDKNRARPFKAPVIWLVGPLAIGGCITLFLFLPTDAQLVFPIWTGVGLIFYFLY
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHH
GYRRSHVLLGISTPPGGENLIEPIRSLVNHEEGERDKEK
HHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIFWRIKSLDSMLATAAKKSLHRSLGVWQLTLLGIGAIIGTGIFVLTAEAAQKAGPGMMI
CEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEEEEHHHHHCCCCHHH
AFVIAGFVCAVAALCYSELSSMVPISGSAYTYSYAVLGELIAWMVGWALILEYSVAAGAV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
AVGWSGYFVGLLNSSLGIKIPFALVNGPFAGGIINLPAVIICILVVSLLIIGTRESATFN
EECCCHHHHHHHCCCCCCEEEHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
ATLVAVKIVALTAFIALALPVADMNHFDPFLPLGTSGVAAAAASIFFAYVGFDAVSTAAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ETKDPQRNLPIALISSLLICTLFYLLISAGVVGAVGAQPLIDATGEGLMPGSREMAAQCK
HCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
LLAAVGQQPVVCSHEALAHVLRQIGWEKVGNLIGLAAFLALPSVILMMLFGQTRIFFVMS
HHHHCCCCCCEECHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
RDGLLPEVLSHIHPRFKTPYIVTLVTGLVVTASAAFLPVGKLANISNSGTLFAFLVVALS
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHH
VMILRIKDKNRARPFKAPVIWLVGPLAIGGCITLFLFLPTDAQLVFPIWTGVGLIFYFLY
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHH
GYRRSHVLLGISTPPGGENLIEPIRSLVNHEEGERDKEK
HHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]