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The map label for this gene is pntAB [H]

Identifier: 114331190

GI number: 114331190

Start: 1248142

End: 1248450

Strand: Direct

Name: pntAB [H]

Synonym: Neut_1192

Alternate gene names: 114331190

Gene position: 1248142-1248450 (Clockwise)

Preceding gene: 114331189

Following gene: 114331191

Centisome position: 46.9

GC content: 46.6

Gene sequence:

>309_bases
ATGATTGGAGAAATTGATCCAACGATCATTAACCTGACAGTATTTGTCCTGGCAGTTTTTGTTGGCTACCATGTGGTGTG
GAATGTGACACCTGCTCTTCATACCCCCTTGATGTCAGTAACAAATGCAATTTCCAGTATCATTCTGGTCGGAGCAATGT
TGGCAGCGGGCTCAGCTGAAGCGGACTGGGGGGCGTGGTTAGGGGCTGCAGCCGTGGTCTTGGCATCCATCAATGTATTC
GGTGGATTTCTCGTTACCCAGCGTATGCTGGAAATGTTTAAGAAAAAAGATAAAAAAGGACAAGCCTAA

Upstream 100 bases:

>100_bases
AGGAAGCCTGGTCTGTACGGCTGGAGAAATTATAGGTAAATCATAAAAGTCGGTTGTATTGTTTACACATAAAATTTATG
AATCTCTATGAGGAAAACAC

Downstream 100 bases:

>100_bases
ATGTCTGTTAACTTCATCGCGCTGGCCTATCTGGTAGCGGCTGTATTTTTTATTCTTTCACTCAAGGGATTAAGTTCGCC
CACTGCTGCACGTCGTGGCA

Product: putative transmembrane NAD(P) transhydrogenase (alpha subunit part 2)

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Pyridine nucleotide transhydrogenase subunit alpha 2 [H]

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MIGEIDPTIINLTVFVLAVFVGYHVVWNVTPALHTPLMSVTNAISSIILVGAMLAAGSAEADWGAWLGAAAVVLASINVF
GGFLVTQRMLEMFKKKDKKGQA

Sequences:

>Translated_102_residues
MIGEIDPTIINLTVFVLAVFVGYHVVWNVTPALHTPLMSVTNAISSIILVGAMLAAGSAEADWGAWLGAAAVVLASINVF
GGFLVTQRMLEMFKKKDKKGQA
>Mature_102_residues
MIGEIDPTIINLTVFVLAVFVGYHVVWNVTPALHTPLMSVTNAISSIILVGAMLAAGSAEADWGAWLGAAAVVLASINVF
GGFLVTQRMLEMFKKKDKKGQA

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=86, Percent_Identity=54.6511627906977, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI122939153, Length=86, Percent_Identity=54.6511627906977, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787887, Length=85, Percent_Identity=64.7058823529412, Blast_Score=108, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17550456, Length=99, Percent_Identity=49.4949494949495, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10816; Mature: 10816

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGEIDPTIINLTVFVLAVFVGYHVVWNVTPALHTPLMSVTNAISSIILVGAMLAAGSAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ADWGAWLGAAAVVLASINVFGGFLVTQRMLEMFKKKDKKGQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIGEIDPTIINLTVFVLAVFVGYHVVWNVTPALHTPLMSVTNAISSIILVGAMLAAGSAE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ADWGAWLGAAAVVLASINVFGGFLVTQRMLEMFKKKDKKGQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9823893; 8662004 [H]