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The map label for this gene is tcp [H]

Identifier: 114331168

GI number: 114331168

Start: 1219779

End: 1222124

Strand: Direct

Name: tcp [H]

Synonym: Neut_1170

Alternate gene names: 114331168

Gene position: 1219779-1222124 (Clockwise)

Preceding gene: 114331167

Following gene: 114331169

Centisome position: 45.84

GC content: 52.26

Gene sequence:

>2346_bases
ATGAGAGTCAATCTGCCGGTTACCAACGTTGAACACGAAATGCGGGATGGCGAATTTCTCGTTTCCAGGACCACGCCCAA
GGGAGTGATTACCTATATCAATGAACCGTTCGTCAGGATGAGCGGCTTTACTGAGCAGGAGCTGATTGGGCAGGCGCACA
ATATTATTCGCCATCCGGATATGCCGCCGGAGGCGTTTGTCGATTTCTGGGACATGCTCAAACAGGGCAGGCCATGGAGT
GGTATGGTCAAGAACCGAAATCAAGATGGCGGTTATTACTGGGTCTTTGCCAACGCCACGCCTGTCAAAGAGCATGGCAA
GGTGACCGGCCATATGTCGGTACGCAGTAAGCCCTCACGTGATCAGATTCAGGCCGCCGAGACACTGTATCGTCAAATGC
GTGAAGGCACAGCAAAAGTACGGATTGTTGCTGGAAAAGTCATTGCCGATACTCCCCTGGGATGGCTACGTGAAAAATTT
CGCCATCTCAGCCTGAAGACCCGGATTATCGGAGCCGGTATCGTGCCACTGCTAGTGATGGCAGGATCGGCCTGGTTGAT
GATGCAAGATCAATTCAGTCTGGCTTTTGCCGGAATGGGGCTGAGCGCCTGCCTGGCGGTCGGGATGGGGATGTGGTTGT
ATCACTGCATTCGCCAGCCGCTGGATACCATGATTCATCATCTGGAAAAGATGGCGCAGGGGGATTACACCACCCAAATC
ACGATTGAGCGGGATGATGAAATCGGGAAGCTGACTGAAGCGCTTAAATCCATGCAAATTCGTGCAGGAATCGATTTCAC
CGAAACCAAGCGGATGAATGTTGAAAATTTGCGCGTACGTAATGCGCTGGATATTGCTACTTCTGCAATCATGATTGCCA
ATAACAGTGGGATGATCATTTTCATGAACCGGATGGTGCGGGAAATCCTTGCCAAAGAGGAGGATGAAGCGGAAGTGCGC
AAATCCCTGCAAAGCCGATTGAAAGCTCTGGCCAGTCAGCAGCAGATTGATAACGTCAGGATCGGAGAGCGGACGTATTC
ACTGGTATTGATGCCAGTTACCAGTGAATCCGGAGAACGAGTGGGTTCAGTAGTTGAGTGGCGTGATCGTACTCAGGAGT
TAACGATTGAAAGGGAGATTATGGATATCGTTCAGGCAGGTGTGGCAGGGGATTTCAGCAAACGCCTGACCTTGATCGGC
AAGGAGGGATTCTTCAGGCAACTGGCCGAAGGTATCAACCGGCTGATGGAAAGTACCTCCCAGGGATTGGATGAATTGGC
ATCTATATTGGAAGCCATGGCGGAAGGCGATTTGACCCAGAAAATTACCCGTGATTATCAGGGAATGCTGGGCAGATTGA
AGGATGATTCGAATTCAACCGTCACTCAACTGACCGGCATTGTCGCCCAGATCAAGGAGGCGGTCGGTCTGATTGGCACC
GCATCGAAAGAAATTGCCGATGGCAACACGGATCTTTCGCAGCGAACCGAGCAACAAGCCGCCAATCTGGAGAAGACAGC
CGCCAGCATGGATGAATTGACTTCAACCGTGAAGCAGAATGCGAGCAATGCACACCAGGCCAACCAGCTTGCTGCCTCTG
CTTCCAGTGTGGCGGTGAAGGGAGGACAGGTTGTCAGTGAAGTGGTGCAGACCATGAGCGAGATCAACGACAGTTCGAAG
AAGATTGTTGACATCATCAGTGTGATCGATGGTATCGCTTTCCAGACCAATATTCTGGCGCTGAATGCAGCGGTGGAAGC
CGCTCGTGCTGGCGAGCAGGGACGGGGGTTTGCGGTAGTTGCGACTGAAGTGCGCACGCTGGCGCAACGTTCAGCGGCTG
CAGCCAAGGAAATCAAGGAGCTGATCAATAACTCGGTACTTAAGGTAGAAGATGGTACTCAGCAGGTGGATCAGGCTGGC
AAGACGATGGAAGAAATCGTGCAATCGGTCAAACACGTGACTGACATCATGGGCGAGATTTCAGCCGCTTCTCAGGAGCA
GAGTCAGGGTATCGAACAAGTGAATCAGGCAATTTCACAGATGGATGAAATCACGCAACAGAATGCGGCGCTGGTGGAAC
AGGCGGCGGCAGCTTCCGAATCGATGCGTGAGCAGGCGGAACAGTTATCGCGCGCTGTGGCTGTATTCAAACTAGAACAG
AGCTCTTTATCCAGTCAGGCAAGTAATCAGCCATTCGTTGAACGACGTGGCCCTAACCGTGCAACCAACGTTGAGCGGCT
ATCTCGGATCAAAAAACCTCAGGCCGGAAACCAGAAAAAAGTGGCTGCCCAGGGCCATATTGCATCGATACCCACCGGCA
CGGGCGGGGAATGGGAAGAGTTCTGA

Upstream 100 bases:

>100_bases
AGAAGCGACCTCTTCCTGCCGCATTGTATTCGCAGTCGTGATGACAGTGATGAATCTGTAATGCTGCATGAATAAAACAA
CCTTTTGAGGAAGCACGATC

Downstream 100 bases:

>100_bases
AATAGAACACAACGCCCGTCTTGGCGAATATGAAGGTGAGGAAGCAATCTCCCTCCCGCTGTCTTTGCGAGGCGAATGGC
TGAAACAATCTAGTAGCAAG

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 781; Mature: 781

Protein sequence:

>781_residues
MRVNLPVTNVEHEMRDGEFLVSRTTPKGVITYINEPFVRMSGFTEQELIGQAHNIIRHPDMPPEAFVDFWDMLKQGRPWS
GMVKNRNQDGGYYWVFANATPVKEHGKVTGHMSVRSKPSRDQIQAAETLYRQMREGTAKVRIVAGKVIADTPLGWLREKF
RHLSLKTRIIGAGIVPLLVMAGSAWLMMQDQFSLAFAGMGLSACLAVGMGMWLYHCIRQPLDTMIHHLEKMAQGDYTTQI
TIERDDEIGKLTEALKSMQIRAGIDFTETKRMNVENLRVRNALDIATSAIMIANNSGMIIFMNRMVREILAKEEDEAEVR
KSLQSRLKALASQQQIDNVRIGERTYSLVLMPVTSESGERVGSVVEWRDRTQELTIEREIMDIVQAGVAGDFSKRLTLIG
KEGFFRQLAEGINRLMESTSQGLDELASILEAMAEGDLTQKITRDYQGMLGRLKDDSNSTVTQLTGIVAQIKEAVGLIGT
ASKEIADGNTDLSQRTEQQAANLEKTAASMDELTSTVKQNASNAHQANQLAASASSVAVKGGQVVSEVVQTMSEINDSSK
KIVDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRTLAQRSAAAAKEIKELINNSVLKVEDGTQQVDQAG
KTMEEIVQSVKHVTDIMGEISAASQEQSQGIEQVNQAISQMDEITQQNAALVEQAAAASESMREQAEQLSRAVAVFKLEQ
SSLSSQASNQPFVERRGPNRATNVERLSRIKKPQAGNQKKVAAQGHIASIPTGTGGEWEEF

Sequences:

>Translated_781_residues
MRVNLPVTNVEHEMRDGEFLVSRTTPKGVITYINEPFVRMSGFTEQELIGQAHNIIRHPDMPPEAFVDFWDMLKQGRPWS
GMVKNRNQDGGYYWVFANATPVKEHGKVTGHMSVRSKPSRDQIQAAETLYRQMREGTAKVRIVAGKVIADTPLGWLREKF
RHLSLKTRIIGAGIVPLLVMAGSAWLMMQDQFSLAFAGMGLSACLAVGMGMWLYHCIRQPLDTMIHHLEKMAQGDYTTQI
TIERDDEIGKLTEALKSMQIRAGIDFTETKRMNVENLRVRNALDIATSAIMIANNSGMIIFMNRMVREILAKEEDEAEVR
KSLQSRLKALASQQQIDNVRIGERTYSLVLMPVTSESGERVGSVVEWRDRTQELTIEREIMDIVQAGVAGDFSKRLTLIG
KEGFFRQLAEGINRLMESTSQGLDELASILEAMAEGDLTQKITRDYQGMLGRLKDDSNSTVTQLTGIVAQIKEAVGLIGT
ASKEIADGNTDLSQRTEQQAANLEKTAASMDELTSTVKQNASNAHQANQLAASASSVAVKGGQVVSEVVQTMSEINDSSK
KIVDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRTLAQRSAAAAKEIKELINNSVLKVEDGTQQVDQAG
KTMEEIVQSVKHVTDIMGEISAASQEQSQGIEQVNQAISQMDEITQQNAALVEQAAAASESMREQAEQLSRAVAVFKLEQ
SSLSSQASNQPFVERRGPNRATNVERLSRIKKPQAGNQKKVAAQGHIASIPTGTGGEWEEF
>Mature_781_residues
MRVNLPVTNVEHEMRDGEFLVSRTTPKGVITYINEPFVRMSGFTEQELIGQAHNIIRHPDMPPEAFVDFWDMLKQGRPWS
GMVKNRNQDGGYYWVFANATPVKEHGKVTGHMSVRSKPSRDQIQAAETLYRQMREGTAKVRIVAGKVIADTPLGWLREKF
RHLSLKTRIIGAGIVPLLVMAGSAWLMMQDQFSLAFAGMGLSACLAVGMGMWLYHCIRQPLDTMIHHLEKMAQGDYTTQI
TIERDDEIGKLTEALKSMQIRAGIDFTETKRMNVENLRVRNALDIATSAIMIANNSGMIIFMNRMVREILAKEEDEAEVR
KSLQSRLKALASQQQIDNVRIGERTYSLVLMPVTSESGERVGSVVEWRDRTQELTIEREIMDIVQAGVAGDFSKRLTLIG
KEGFFRQLAEGINRLMESTSQGLDELASILEAMAEGDLTQKITRDYQGMLGRLKDDSNSTVTQLTGIVAQIKEAVGLIGT
ASKEIADGNTDLSQRTEQQAANLEKTAASMDELTSTVKQNASNAHQANQLAASASSVAVKGGQVVSEVVQTMSEINDSSK
KIVDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVATEVRTLAQRSAAAAKEIKELINNSVLKVEDGTQQVDQAG
KTMEEIVQSVKHVTDIMGEISAASQEQSQGIEQVNQAISQMDEITQQNAALVEQAAAASESMREQAEQLSRAVAVFKLEQ
SSLSSQASNQPFVERRGPNRATNVERLSRIKKPQAGNQKKVAAQGHIASIPTGTGGEWEEF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=336, Percent_Identity=55.952380952381, Blast_Score=306, Evalue=5e-84,
Organism=Escherichia coli, GI2367378, Length=318, Percent_Identity=56.9182389937107, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1787690, Length=304, Percent_Identity=56.25, Blast_Score=293, Evalue=3e-80,
Organism=Escherichia coli, GI1788194, Length=315, Percent_Identity=54.9206349206349, Blast_Score=285, Evalue=8e-78,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=46, Blast_Score=220, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 85819; Mature: 85819

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVNLPVTNVEHEMRDGEFLVSRTTPKGVITYINEPFVRMSGFTEQELIGQAHNIIRHPD
CEECCCCCCCHHHHCCCCEEEEECCCCCEEEECCCCHHHHCCCCHHHHHHHHHHHHCCCC
MPPEAFVDFWDMLKQGRPWSGMVKNRNQDGGYYWVFANATPVKEHGKVTGHMSVRSKPSR
CCHHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEEECCCCCHHCCCEEEEEEECCCCCH
DQIQAAETLYRQMREGTAKVRIVAGKVIADTPLGWLREKFRHLSLKTRIIGAGIVPLLVM
HHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AGSAWLMMQDQFSLAFAGMGLSACLAVGMGMWLYHCIRQPLDTMIHHLEKMAQGDYTTQI
HCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TIERDDEIGKLTEALKSMQIRAGIDFTETKRMNVENLRVRNALDIATSAIMIANNSGMII
EEECCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCEEE
FMNRMVREILAKEEDEAEVRKSLQSRLKALASQQQIDNVRIGERTYSLVLMPVTSESGER
EHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEEEECCCCCHH
VGSVVEWRDRTQELTIEREIMDIVQAGVAGDFSKRLTLIGKEGFFRQLAEGINRLMESTS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCHHHHHHHHHHHHHHHHHHH
QGLDELASILEAMAEGDLTQKITRDYQGMLGRLKDDSNSTVTQLTGIVAQIKEAVGLIGT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
ASKEIADGNTDLSQRTEQQAANLEKTAASMDELTSTVKQNASNAHQANQLAASASSVAVK
CCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
GGQVVSEVVQTMSEINDSSKKIVDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
ATEVRTLAQRSAAAAKEIKELINNSVLKVEDGTQQVDQAGKTMEEIVQSVKHVTDIMGEI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAASQEQSQGIEQVNQAISQMDEITQQNAALVEQAAAASESMREQAEQLSRAVAVFKLEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLSSQASNQPFVERRGPNRATNVERLSRIKKPQAGNQKKVAAQGHIASIPTGTGGEWEE
HHHHHHCCCCCCHHCCCCCCCCCHHHHHHHCCCCCCCCCCEECCCCEEECCCCCCCCCCC
F
C
>Mature Secondary Structure
MRVNLPVTNVEHEMRDGEFLVSRTTPKGVITYINEPFVRMSGFTEQELIGQAHNIIRHPD
CEECCCCCCCHHHHCCCCEEEEECCCCCEEEECCCCHHHHCCCCHHHHHHHHHHHHCCCC
MPPEAFVDFWDMLKQGRPWSGMVKNRNQDGGYYWVFANATPVKEHGKVTGHMSVRSKPSR
CCHHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEEECCCCCHHCCCEEEEEEECCCCCH
DQIQAAETLYRQMREGTAKVRIVAGKVIADTPLGWLREKFRHLSLKTRIIGAGIVPLLVM
HHHHHHHHHHHHHHCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AGSAWLMMQDQFSLAFAGMGLSACLAVGMGMWLYHCIRQPLDTMIHHLEKMAQGDYTTQI
HCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TIERDDEIGKLTEALKSMQIRAGIDFTETKRMNVENLRVRNALDIATSAIMIANNSGMII
EEECCCHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHEEEEECCCCEEE
FMNRMVREILAKEEDEAEVRKSLQSRLKALASQQQIDNVRIGERTYSLVLMPVTSESGER
EHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEEEEEEEECCCCCHH
VGSVVEWRDRTQELTIEREIMDIVQAGVAGDFSKRLTLIGKEGFFRQLAEGINRLMESTS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCHHHHHHHHHHHHHHHHHHH
QGLDELASILEAMAEGDLTQKITRDYQGMLGRLKDDSNSTVTQLTGIVAQIKEAVGLIGT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
ASKEIADGNTDLSQRTEQQAANLEKTAASMDELTSTVKQNASNAHQANQLAASASSVAVK
CCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
GGQVVSEVVQTMSEINDSSKKIVDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVV
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
ATEVRTLAQRSAAAAKEIKELINNSVLKVEDGTQQVDQAGKTMEEIVQSVKHVTDIMGEI
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAASQEQSQGIEQVNQAISQMDEITQQNAALVEQAAAASESMREQAEQLSRAVAVFKLEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLSSQASNQPFVERRGPNRATNVERLSRIKKPQAGNQKKVAAQGHIASIPTGTGGEWEE
HHHHHHCCCCCCHHCCCCCCCCCHHHHHHHCCCCCCCCCCEECCCCEEECCCCCCCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]