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The map label for this gene is intA [H]

Identifier: 114331123

GI number: 114331123

Start: 1164412

End: 1165593

Strand: Reverse

Name: intA [H]

Synonym: Neut_1125

Alternate gene names: 114331123

Gene position: 1165593-1164412 (Counterclockwise)

Preceding gene: 114331125

Following gene: 114331122

Centisome position: 43.8

GC content: 48.05

Gene sequence:

>1182_bases
ATGAAACTAACTGATTCAGCCATTCGAGCTGCAAAACCCAAAGAGAAGCAATACAAGCTGACAGACGGCAACGGATTGAC
CCTGCTGATATATCCTGACGGTTCAAAGCACTGGCGGTACCGGTATTTATTCAATGAGAAAGAATCCATGCTTTCCCTTG
GGAAATACCCGGAAACAACCCTGGCGCAAGCCCGATCAATTCATGATGGGTACAAGGCGATACTAAAACAGGGCATCAAT
CCATCGACTCATCGCAAGGAAGAAAAACGGAAAGCGATCGTGTCTGTTGAAAACAGTTTCGAGGCGGTGGCGCGGACATG
GTGGATGCATTGGAAGCATGCCAAGACAGAGCGCCATGTAGCTTATACCTTGAGAAGAATGGAAGCCGATATATTCCCGT
TCATTGGTGCAAAACCAGTCAATACACTCACAGCCATGCATTTTATTGAGCTTGTGTACAAGGTGCAAAGCCGTGGCGCG
CTGGATATTGCAAAACGTGTTTTAACCATGTGCGGGCAGGTTATGCGCTATGCGGTGCAGCACGGGTTATCAGAACGAAA
CCCGGCAGCAGACATAAAACCAGCCGACATTCTAAAGAAACGGAAAAAAGTTAATCACAAGCGGATACCTGAATCAGAGC
TGCCGGATTTACTCCAGAAGATTAATCAGTACGACGGGCAACCACTTACACGACTGGCTTTGCAGTTAATGACGCTAACA
TTCATTCGGACAAGTGAACTGATCGGCGGACGGTGGGAAGAGATTAGCTTTGATAATGCCGAATGGCGTATCCCGCCAGA
GCGCATGAAAATGCGTAGTCAGCATATCGTCCCCTTGAGCGACCAGGCAATAACTGTCTTGCGCGAAATCAAGGCATTGA
ACAGTGACCCGGTTCTGTTGTTCCCCAGCGAGCGACGTAATGGCAAGACCATGAGCAACAACACCATTATTTATGCGCTA
TACCGCATAGGTTACAAGGGGCGTATGACGGGGCACGGCTTCCGTGGACTGGCATCAACTGTCTTGCATGAGAAAAATTT
CGACCACAAATGGATAGAACTACAACTGGCACATGCAGAGCGTGATGAAGTTTCAGCGGCTTACAATCACGCCCTGTACC
TTGAACAGCGCAGGAAAATGATGCAATGGTGGGGGGAATATATTGAGATGAAAGGAAAATGA

Upstream 100 bases:

>100_bases
TCATTCATTGGCAACCTTGGTAAAACAGGGTAACATTTCAAAAAACGGGTAGAAAACCGGATATATTTTTTACCCATTTC
ATTTCTACCCGGTTTTACCA

Downstream 100 bases:

>100_bases
CAAAAAGATTCCCGCTAATAGGATCTGGGTAGTATTTGTACAAAGCACAACATATGGTACTATTGACCACCCTTGACCAC
TAGATACAAGGGATTGCCCG

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKLTDSAIRAAKPKEKQYKLTDGNGLTLLIYPDGSKHWRYRYLFNEKESMLSLGKYPETTLAQARSIHDGYKAILKQGIN
PSTHRKEEKRKAIVSVENSFEAVARTWWMHWKHAKTERHVAYTLRRMEADIFPFIGAKPVNTLTAMHFIELVYKVQSRGA
LDIAKRVLTMCGQVMRYAVQHGLSERNPAADIKPADILKKRKKVNHKRIPESELPDLLQKINQYDGQPLTRLALQLMTLT
FIRTSELIGGRWEEISFDNAEWRIPPERMKMRSQHIVPLSDQAITVLREIKALNSDPVLLFPSERRNGKTMSNNTIIYAL
YRIGYKGRMTGHGFRGLASTVLHEKNFDHKWIELQLAHAERDEVSAAYNHALYLEQRRKMMQWWGEYIEMKGK

Sequences:

>Translated_393_residues
MKLTDSAIRAAKPKEKQYKLTDGNGLTLLIYPDGSKHWRYRYLFNEKESMLSLGKYPETTLAQARSIHDGYKAILKQGIN
PSTHRKEEKRKAIVSVENSFEAVARTWWMHWKHAKTERHVAYTLRRMEADIFPFIGAKPVNTLTAMHFIELVYKVQSRGA
LDIAKRVLTMCGQVMRYAVQHGLSERNPAADIKPADILKKRKKVNHKRIPESELPDLLQKINQYDGQPLTRLALQLMTLT
FIRTSELIGGRWEEISFDNAEWRIPPERMKMRSQHIVPLSDQAITVLREIKALNSDPVLLFPSERRNGKTMSNNTIIYAL
YRIGYKGRMTGHGFRGLASTVLHEKNFDHKWIELQLAHAERDEVSAAYNHALYLEQRRKMMQWWGEYIEMKGK
>Mature_393_residues
MKLTDSAIRAAKPKEKQYKLTDGNGLTLLIYPDGSKHWRYRYLFNEKESMLSLGKYPETTLAQARSIHDGYKAILKQGIN
PSTHRKEEKRKAIVSVENSFEAVARTWWMHWKHAKTERHVAYTLRRMEADIFPFIGAKPVNTLTAMHFIELVYKVQSRGA
LDIAKRVLTMCGQVMRYAVQHGLSERNPAADIKPADILKKRKKVNHKRIPESELPDLLQKINQYDGQPLTRLALQLMTLT
FIRTSELIGGRWEEISFDNAEWRIPPERMKMRSQHIVPLSDQAITVLREIKALNSDPVLLFPSERRNGKTMSNNTIIYAL
YRIGYKGRMTGHGFRGLASTVLHEKNFDHKWIELQLAHAERDEVSAAYNHALYLEQRRKMMQWWGEYIEMKGK

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=389, Percent_Identity=38.8174807197943, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI1788690, Length=391, Percent_Identity=35.0383631713555, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI145693166, Length=390, Percent_Identity=36.4102564102564, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45729; Mature: 45729

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTDSAIRAAKPKEKQYKLTDGNGLTLLIYPDGSKHWRYRYLFNEKESMLSLGKYPETT
CCCCHHHHHHCCCCCCCEEEECCCCEEEEEEECCCCCEEEEEEECCHHHHHHHCCCCCHH
LAQARSIHDGYKAILKQGINPSTHRKEEKRKAIVSVENSFEAVARTWWMHWKHAKTERHV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AYTLRRMEADIFPFIGAKPVNTLTAMHFIELVYKVQSRGALDIAKRVLTMCGQVMRYAVQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
HGLSERNPAADIKPADILKKRKKVNHKRIPESELPDLLQKINQYDGQPLTRLALQLMTLT
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FIRTSELIGGRWEEISFDNAEWRIPPERMKMRSQHIVPLSDQAITVLREIKALNSDPVLL
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEE
FPSERRNGKTMSNNTIIYALYRIGYKGRMTGHGFRGLASTVLHEKNFDHKWIELQLAHAE
ECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCC
RDEVSAAYNHALYLEQRRKMMQWWGEYIEMKGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLTDSAIRAAKPKEKQYKLTDGNGLTLLIYPDGSKHWRYRYLFNEKESMLSLGKYPETT
CCCCHHHHHHCCCCCCCEEEECCCCEEEEEEECCCCCEEEEEEECCHHHHHHHCCCCCHH
LAQARSIHDGYKAILKQGINPSTHRKEEKRKAIVSVENSFEAVARTWWMHWKHAKTERHV
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AYTLRRMEADIFPFIGAKPVNTLTAMHFIELVYKVQSRGALDIAKRVLTMCGQVMRYAVQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
HGLSERNPAADIKPADILKKRKKVNHKRIPESELPDLLQKINQYDGQPLTRLALQLMTLT
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
FIRTSELIGGRWEEISFDNAEWRIPPERMKMRSQHIVPLSDQAITVLREIKALNSDPVLL
HHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEE
FPSERRNGKTMSNNTIIYALYRIGYKGRMTGHGFRGLASTVLHEKNFDHKWIELQLAHAE
ECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCC
RDEVSAAYNHALYLEQRRKMMQWWGEYIEMKGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]