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The map label for this gene is cyaB [H]

Identifier: 114331116

GI number: 114331116

Start: 1157153

End: 1158871

Strand: Reverse

Name: cyaB [H]

Synonym: Neut_1118

Alternate gene names: 114331116

Gene position: 1158871-1157153 (Counterclockwise)

Preceding gene: 114331117

Following gene: 114331115

Centisome position: 43.55

GC content: 45.67

Gene sequence:

>1719_bases
ATGATGAAATCTATCAATTCTGTGCAAATGATCACAGCTAAAACACCTTTTGCAGCAAATTCAAGTGAAGCCAGGCCGAT
CGCTATTCGATCCAGTTACCCGATCATCATTACTTCGCTTGAGCAAAATATCTGGCAAGAGCTTGAACGAAAAATTGCAC
ACTCACTGGAACGTTTGTGTTGCCAGCGCCTACTGGATTCAACCGTACTGCTATTACACAAGCTGATTACGAATCTGGTT
AAAACCATGCATCGTCATGCTTTCCAGCAGGCAATTGAAGGTGATCTCGGTCTTAATGTCGCCAGCAGGAATAGCGTATT
TAATGAACTCCTGCAAAACGAACTGGTCATGCATGGCGATCGGAATATCGAGCAATTCTGTAAAGAGAACAATTTTCAGA
TCATGCTGACTTTCCCTGAAGAAAAAGATACTTTGATACAGATTGAATACCCGATCAGCTGTGACGATAGCGCCTATCTG
GATAACAAGCTTGCCAGAGCAATCGGATTCGTATTGTCAAAACAGACTCATGATAAGTATTCGCCAGGATATTCTGCTGC
CAGAATAGTAAGGAATATTGCAGAACATCACCTCTATCAGTCGCAGACAGGACACTCTCAATTGCTGACCTGTGCGGAGG
AGTCAGATAAGGCCCAGGTTATTTTCAGCAAGCTGGGCTACAGCATTATCGTTTTCTCCAGCGCCGGGGATATTCTGGCT
ATATCACCCACAATTCTCAACAACCTGAAACTGGAAGTATCGCCTGTTTCAGCACATACCCTTGCAGGTATTATCCCCAG
CCATTTTTATAATGATGTGTTGTGGGGGCTTGCGTTGGAATTACAGAATGGTTTGTTCGAGAACTACAGAACCCGCATCA
GGCTGCCCCATGATGACAGCCTGTCGATACTTTTCAATATTAGTGGTTACCGTCACCATGACATGACAATCCACACGATG
TGGCAAATCGTATCGCTGGATCACAAGGCCACTGACACACTGGCAGAAGGCTCTATCCTCAACGAAGCTCGTGTGCATAA
CATTACCCGTAATTATGTGCCTCAGCTAGTCGAGCAGAAAGCCAGAGAAATCGTCCGGCTGGGTGGCAATGCACTCCCTA
ATGAAGAATGTCAGCTTGCCGTTCTGTTTTGCGATATTGCCGGCTTTACCACTTACGTGGAAAACAATGAAAAAGAAGAA
TCCGTTATCCACACGCTCAATCTGATACTTGGCAGAATCACAAAAGCAGTCAAACAGCATGAAGGCGTCATCGACAAGTT
CATGGGAGATTGCGTCATGGCGCTCTTCAAGGAACCATATAAAGCCGTACTGGCCGCACTCGACATTCACAAACATTCCC
ATGATTTCAATAGTCTGCGGATGCGTGCCAGCAAAGATCTGCTGCTATTGCGTATCGGCATCCATTGGGGAAAGGTTGTA
ATTGGCAATGTCGGTGCTTCAGGCAGGCTAGACTGGACAACAATTGGTGATGTTGTGAATACCGCTGCCCGGCTTGAGAA
AAGTTGTTGTCCGGGCGCGATACTGATTAGTGAAGAATTACATGAAGCCATTGCACAGATTGATCACACCGAGATCAGCT
TCAGCAAGCGCTTTTATCTCAAACTGAAAGGAAAACGCAACAAACAGGCTGTCCGCTACGTCCAGATAACCAGCCAACCT
CTTTTGCATGATATTTTTATCACCCGTTCGAGAGCCTAA

Upstream 100 bases:

>100_bases
TGTGATCTGGATGTTCGCAAGGAGAAATTGATAGCTTACGGGCTAAGTGAAGAATATGCCGATCACCTACTCGACGAGGC
GTTCTTTCAAAAATTGATCA

Downstream 100 bases:

>100_bases
ATTCAAGGAGATCATTGGGCACTGCCATATAACCCTGTGTGATCTCGGCTGGATCAAAATACAGAGCCAGGAGGGGAGAA
TTCTTGCTTCCCGATATCGA

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MMKSINSVQMITAKTPFAANSSEARPIAIRSSYPIIITSLEQNIWQELERKIAHSLERLCCQRLLDSTVLLLHKLITNLV
KTMHRHAFQQAIEGDLGLNVASRNSVFNELLQNELVMHGDRNIEQFCKENNFQIMLTFPEEKDTLIQIEYPISCDDSAYL
DNKLARAIGFVLSKQTHDKYSPGYSAARIVRNIAEHHLYQSQTGHSQLLTCAEESDKAQVIFSKLGYSIIVFSSAGDILA
ISPTILNNLKLEVSPVSAHTLAGIIPSHFYNDVLWGLALELQNGLFENYRTRIRLPHDDSLSILFNISGYRHHDMTIHTM
WQIVSLDHKATDTLAEGSILNEARVHNITRNYVPQLVEQKAREIVRLGGNALPNEECQLAVLFCDIAGFTTYVENNEKEE
SVIHTLNLILGRITKAVKQHEGVIDKFMGDCVMALFKEPYKAVLAALDIHKHSHDFNSLRMRASKDLLLLRIGIHWGKVV
IGNVGASGRLDWTTIGDVVNTAARLEKSCCPGAILISEELHEAIAQIDHTEISFSKRFYLKLKGKRNKQAVRYVQITSQP
LLHDIFITRSRA

Sequences:

>Translated_572_residues
MMKSINSVQMITAKTPFAANSSEARPIAIRSSYPIIITSLEQNIWQELERKIAHSLERLCCQRLLDSTVLLLHKLITNLV
KTMHRHAFQQAIEGDLGLNVASRNSVFNELLQNELVMHGDRNIEQFCKENNFQIMLTFPEEKDTLIQIEYPISCDDSAYL
DNKLARAIGFVLSKQTHDKYSPGYSAARIVRNIAEHHLYQSQTGHSQLLTCAEESDKAQVIFSKLGYSIIVFSSAGDILA
ISPTILNNLKLEVSPVSAHTLAGIIPSHFYNDVLWGLALELQNGLFENYRTRIRLPHDDSLSILFNISGYRHHDMTIHTM
WQIVSLDHKATDTLAEGSILNEARVHNITRNYVPQLVEQKAREIVRLGGNALPNEECQLAVLFCDIAGFTTYVENNEKEE
SVIHTLNLILGRITKAVKQHEGVIDKFMGDCVMALFKEPYKAVLAALDIHKHSHDFNSLRMRASKDLLLLRIGIHWGKVV
IGNVGASGRLDWTTIGDVVNTAARLEKSCCPGAILISEELHEAIAQIDHTEISFSKRFYLKLKGKRNKQAVRYVQITSQP
LLHDIFITRSRA
>Mature_572_residues
MMKSINSVQMITAKTPFAANSSEARPIAIRSSYPIIITSLEQNIWQELERKIAHSLERLCCQRLLDSTVLLLHKLITNLV
KTMHRHAFQQAIEGDLGLNVASRNSVFNELLQNELVMHGDRNIEQFCKENNFQIMLTFPEEKDTLIQIEYPISCDDSAYL
DNKLARAIGFVLSKQTHDKYSPGYSAARIVRNIAEHHLYQSQTGHSQLLTCAEESDKAQVIFSKLGYSIIVFSSAGDILA
ISPTILNNLKLEVSPVSAHTLAGIIPSHFYNDVLWGLALELQNGLFENYRTRIRLPHDDSLSILFNISGYRHHDMTIHTM
WQIVSLDHKATDTLAEGSILNEARVHNITRNYVPQLVEQKAREIVRLGGNALPNEECQLAVLFCDIAGFTTYVENNEKEE
SVIHTLNLILGRITKAVKQHEGVIDKFMGDCVMALFKEPYKAVLAALDIHKHSHDFNSLRMRASKDLLLLRIGIHWGKVV
IGNVGASGRLDWTTIGDVVNTAARLEKSCCPGAILISEELHEAIAQIDHTEISFSKRFYLKLKGKRNKQAVRYVQITSQP
LLHDIFITRSRA

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 64548; Mature: 64548

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKSINSVQMITAKTPFAANSSEARPIAIRSSYPIIITSLEQNIWQELERKIAHSLERLC
CCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
CQRLLDSTVLLLHKLITNLVKTMHRHAFQQAIEGDLGLNVASRNSVFNELLQNELVMHGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHCCC
RNIEQFCKENNFQIMLTFPEEKDTLIQIEYPISCDDSAYLDNKLARAIGFVLSKQTHDKY
CCHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
SPGYSAARIVRNIAEHHLYQSQTGHSQLLTCAEESDKAQVIFSKLGYSIIVFSSAGDILA
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCEEE
ISPTILNNLKLEVSPVSAHTLAGIIPSHFYNDVLWGLALELQNGLFENYRTRIRLPHDDS
ECHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCC
LSILFNISGYRHHDMTIHTMWQIVSLDHKATDTLAEGSILNEARVHNITRNYVPQLVEQK
EEEEEEECCEEECCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AREIVRLGGNALPNEECQLAVLFCDIAGFTTYVENNEKEESVIHTLNLILGRITKAVKQH
HHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGVIDKFMGDCVMALFKEPYKAVLAALDIHKHSHDFNSLRMRASKDLLLLRIGIHWGKVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCEE
IGNVGASGRLDWTTIGDVVNTAARLEKSCCPGAILISEELHEAIAQIDHTEISFSKRFYL
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEEECEEEEE
KLKGKRNKQAVRYVQITSQPLLHDIFITRSRA
EECCCCCCCCEEEEEECCCCHHHHHHHCCCCC
>Mature Secondary Structure
MMKSINSVQMITAKTPFAANSSEARPIAIRSSYPIIITSLEQNIWQELERKIAHSLERLC
CCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
CQRLLDSTVLLLHKLITNLVKTMHRHAFQQAIEGDLGLNVASRNSVFNELLQNELVMHGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHCCC
RNIEQFCKENNFQIMLTFPEEKDTLIQIEYPISCDDSAYLDNKLARAIGFVLSKQTHDKY
CCHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
SPGYSAARIVRNIAEHHLYQSQTGHSQLLTCAEESDKAQVIFSKLGYSIIVFSSAGDILA
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCEEE
ISPTILNNLKLEVSPVSAHTLAGIIPSHFYNDVLWGLALELQNGLFENYRTRIRLPHDDS
ECHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCC
LSILFNISGYRHHDMTIHTMWQIVSLDHKATDTLAEGSILNEARVHNITRNYVPQLVEQK
EEEEEEECCEEECCCHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
AREIVRLGGNALPNEECQLAVLFCDIAGFTTYVENNEKEESVIHTLNLILGRITKAVKQH
HHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
EGVIDKFMGDCVMALFKEPYKAVLAALDIHKHSHDFNSLRMRASKDLLLLRIGIHWGKVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCEE
IGNVGASGRLDWTTIGDVVNTAARLEKSCCPGAILISEELHEAIAQIDHTEISFSKRFYL
EECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCEEEECEEEEE
KLKGKRNKQAVRYVQITSQPLLHDIFITRSRA
EECCCCCCCCEEEEEECCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]