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The map label for this gene is coaE [H]

Identifier: 114331044

GI number: 114331044

Start: 1083227

End: 1083838

Strand: Direct

Name: coaE [H]

Synonym: Neut_1045

Alternate gene names: 114331044

Gene position: 1083227-1083838 (Clockwise)

Preceding gene: 114331043

Following gene: 114331045

Centisome position: 40.71

GC content: 50.0

Gene sequence:

>612_bases
ATGGGATTCATTATCGGGCTAACGGGTGGAATCGGCAGTGGCAAGACCAGTGTGGCTGATCTGTTCCAGGAGCTGGGTAT
TGAAATTATTGATACTGATCACTTGGCGCATGAACTAATTCGCCCAGGTGGTAGTGCGATTCAGGGAATTCGTGTCGTGT
TTGGTGACCATTTTATACTGGAGGATGGTTCACTGAATCGAGTGGCTATGCGCGAGCTCGTATTCTCTGATGAAGTGGCG
CGGCGTAAGCTCGAAGCCATACTTCACCCGCTGATCTATCAGGAAAGCAGGCGACGTCTCCCGCTGATTCAATCCAGTTA
CGGCATTCTGGTCGTGCCTTTGTTACTGGAGGCTGAAGATTATCCTGAGCTGATTGATCGTGTGCTGGTGGTTGATTGTC
CAGAATCCCTGCAAATTTCCCGTACCATGCAGCGTAGCAAGCTGAAGGAACAGGAAGTACGTAAAGTGATGGCCGCACAG
TGCTCACGTGACGAACGCCTTGCTCTGGCTGATGATGTGATTATCAACGACTCCGACAATCAGCACCTGCGGCAACAGGT
ACGAATGCTACATCAGAAATATCTTGCGCTTGTTGACAAACACAGCTTCTGA

Upstream 100 bases:

>100_bases
TACAACACTTCCCTTTGGTCCTTATCTGGCAGGAGGAGGATTAATTGCTTTGTTCTGGGGCAGTCAGATCAATCAGGCAT
ACCTGGCCATGTTTTGACGT

Downstream 100 bases:

>100_bases
ACGATTCTGGTAAGATGCATGTAACTGCAGTTTTCTGCTATGCTTTAACGTTCCTACGTCATCTTACTTACTGTGATCTG
TTACGAATTACCCCTGAACG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MGFIIGLTGGIGSGKTSVADLFQELGIEIIDTDHLAHELIRPGGSAIQGIRVVFGDHFILEDGSLNRVAMRELVFSDEVA
RRKLEAILHPLIYQESRRRLPLIQSSYGILVVPLLLEAEDYPELIDRVLVVDCPESLQISRTMQRSKLKEQEVRKVMAAQ
CSRDERLALADDVIINDSDNQHLRQQVRMLHQKYLALVDKHSF

Sequences:

>Translated_203_residues
MGFIIGLTGGIGSGKTSVADLFQELGIEIIDTDHLAHELIRPGGSAIQGIRVVFGDHFILEDGSLNRVAMRELVFSDEVA
RRKLEAILHPLIYQESRRRLPLIQSSYGILVVPLLLEAEDYPELIDRVLVVDCPESLQISRTMQRSKLKEQEVRKVMAAQ
CSRDERLALADDVIINDSDNQHLRQQVRMLHQKYLALVDKHSF
>Mature_202_residues
GFIIGLTGGIGSGKTSVADLFQELGIEIIDTDHLAHELIRPGGSAIQGIRVVFGDHFILEDGSLNRVAMRELVFSDEVAR
RKLEAILHPLIYQESRRRLPLIQSSYGILVVPLLLEAEDYPELIDRVLVVDCPESLQISRTMQRSKLKEQEVRKVMAAQC
SRDERLALADDVIINDSDNQHLRQQVRMLHQKYLALVDKHSF

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=34.8958333333333, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=34.8958333333333, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI110227607, Length=202, Percent_Identity=30.6930693069307, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI110227605, Length=202, Percent_Identity=30.6930693069307, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI110227603, Length=202, Percent_Identity=30.6930693069307, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI110227601, Length=202, Percent_Identity=30.6930693069307, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI205277394, Length=202, Percent_Identity=30.6930693069307, Blast_Score=82, Evalue=3e-16,
Organism=Escherichia coli, GI1786292, Length=200, Percent_Identity=43, Blast_Score=159, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17554944, Length=190, Percent_Identity=30, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25143409, Length=172, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=199, Percent_Identity=31.6582914572864, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644728, Length=178, Percent_Identity=32.0224719101124, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24658602, Length=189, Percent_Identity=29.6296296296296, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22951; Mature: 22820

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFIIGLTGGIGSGKTSVADLFQELGIEIIDTDHLAHELIRPGGSAIQGIRVVFGDHFIL
CCEEEEECCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHCCCCHHHHHHHHEECCEEEE
EDGSLNRVAMRELVFSDEVARRKLEAILHPLIYQESRRRLPLIQSSYGILVVPLLLEAED
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHCCCC
YPELIDRVLVVDCPESLQISRTMQRSKLKEQEVRKVMAAQCSRDERLALADDVIINDSDN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCC
QHLRQQVRMLHQKYLALVDKHSF
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GFIIGLTGGIGSGKTSVADLFQELGIEIIDTDHLAHELIRPGGSAIQGIRVVFGDHFIL
CEEEEECCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHCCCCHHHHHHHHEECCEEEE
EDGSLNRVAMRELVFSDEVARRKLEAILHPLIYQESRRRLPLIQSSYGILVVPLLLEAED
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHCCCC
YPELIDRVLVVDCPESLQISRTMQRSKLKEQEVRKVMAAQCSRDERLALADDVIINDSDN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCC
QHLRQQVRMLHQKYLALVDKHSF
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]