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The map label for this gene is hflX [H]

Identifier: 114330965

GI number: 114330965

Start: 992389

End: 993522

Strand: Direct

Name: hflX [H]

Synonym: Neut_0962

Alternate gene names: 114330965

Gene position: 992389-993522 (Clockwise)

Preceding gene: 114330964

Following gene: 114330966

Centisome position: 37.29

GC content: 46.65

Gene sequence:

>1134_bases
ATGAATCATGACATCGGAACGGCAGCGGATAATACCGCAATATTAGTAGATATCAATTTTGGCAAAAATGATAAGGAAAG
TCTGGATGAGCTGAAAGAGCTTGCTTACAGTGATCAACTGTCCATAGTTGCGGTGGTCGAAGGAACACGAAAGCAGCCCG
ATCCTGCTACTTTCATCGGAAAAGGCAAGGTGGAGGAAATCAGCCAGATAGTGGTGCAAACACAAGCTGCAATGGTGATA
TTCAACCACGAGCTGTCTCCAATACAGCAAAGAAATCTTTCCACAGCACTGGCCTGTCGCATCATAGATCGTACCAGTCT
GATTCTGGATATCTTTGCGCAGCGTGCCAAAAGCCACGAAGGTAAACTACAGGTTGAGCTGGCTCAGCTGGAGTACCTTT
CCACACGGCTGGTGAGAGGATGGACACATCTGGAGCGCCAAAAAGGTGGAATTGGTCTGCGTGGCCCCGGGGAGACCCAG
CTGGAAACTGACCGACGCTTGCTAGCAAAGCGCGTAAAATTCCTGAAGGAGAAGCTGGCTAAACTTAAACAGCAACGAGA
TGTGCAACGGCGCGCGAGAAAACGCTCTGAAATCATGTCCGTTTCCATTGTGGGTTATACCAATGCTGGTAAGTCAACTT
TGTTCAACCGGCTTGTTCGGTCGGATGCATATGCTGCAGACAAGTTGTTTGCTACGTTGGATACGACTACCAGGAGACTT
TTTCTTCCAGAACGTGGTTTGATCGTAATTTCTGATACAGTTGGTTTTATTCGGGATTTGCCGCATACGCTTGTCGCCGC
GTTCCGTGCCACACTGGAAGAAACCATACAGGCCGACCTGCTTTTGCATGTGGTTGATGTATCCAGTTCCAATCGGGATG
TGCAAATCAGTGAGGTTAATAAATTATTGCAGGAAATTGGGGCAGATACTATACCGCAAATCCTGATTTTGAATAAAATC
GACCTCATTGAGCAGGGTTCGTCAGAAAATTACATGCGCGATGAGTATGGTAGAATCGCAAGAATTCATCTCAGTGCAAG
GACGGGAGCAGGTTTTGGTTATCTCTATGAAGCGCTGGTAGAAGCGTTTGATCAAAACTTGAATAAATTAAGCAGCATTC
AGCAACATCCGTAA

Upstream 100 bases:

>100_bases
AATTCTGTTACACAGATGGTTTATAAACATGCTATTTCTACTATAGTACCAGGTAAGGCAGTTTCAATTCCGGTGCCAGC
TGAAACACTGCCCGAGTAAG

Downstream 100 bases:

>100_bases
GCATGAACGACAATGTCCGTGCCACTTCTATAAATAATGAAAAGGACTAAATCAACATGGGCTTGAATGATCCGCAATGG
GGGAAAAGGAGAGGTAATTC

Product: small GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MNHDIGTAADNTAILVDINFGKNDKESLDELKELAYSDQLSIVAVVEGTRKQPDPATFIGKGKVEEISQIVVQTQAAMVI
FNHELSPIQQRNLSTALACRIIDRTSLILDIFAQRAKSHEGKLQVELAQLEYLSTRLVRGWTHLERQKGGIGLRGPGETQ
LETDRRLLAKRVKFLKEKLAKLKQQRDVQRRARKRSEIMSVSIVGYTNAGKSTLFNRLVRSDAYAADKLFATLDTTTRRL
FLPERGLIVISDTVGFIRDLPHTLVAAFRATLEETIQADLLLHVVDVSSSNRDVQISEVNKLLQEIGADTIPQILILNKI
DLIEQGSSENYMRDEYGRIARIHLSARTGAGFGYLYEALVEAFDQNLNKLSSIQQHP

Sequences:

>Translated_377_residues
MNHDIGTAADNTAILVDINFGKNDKESLDELKELAYSDQLSIVAVVEGTRKQPDPATFIGKGKVEEISQIVVQTQAAMVI
FNHELSPIQQRNLSTALACRIIDRTSLILDIFAQRAKSHEGKLQVELAQLEYLSTRLVRGWTHLERQKGGIGLRGPGETQ
LETDRRLLAKRVKFLKEKLAKLKQQRDVQRRARKRSEIMSVSIVGYTNAGKSTLFNRLVRSDAYAADKLFATLDTTTRRL
FLPERGLIVISDTVGFIRDLPHTLVAAFRATLEETIQADLLLHVVDVSSSNRDVQISEVNKLLQEIGADTIPQILILNKI
DLIEQGSSENYMRDEYGRIARIHLSARTGAGFGYLYEALVEAFDQNLNKLSSIQQHP
>Mature_377_residues
MNHDIGTAADNTAILVDINFGKNDKESLDELKELAYSDQLSIVAVVEGTRKQPDPATFIGKGKVEEISQIVVQTQAAMVI
FNHELSPIQQRNLSTALACRIIDRTSLILDIFAQRAKSHEGKLQVELAQLEYLSTRLVRGWTHLERQKGGIGLRGPGETQ
LETDRRLLAKRVKFLKEKLAKLKQQRDVQRRARKRSEIMSVSIVGYTNAGKSTLFNRLVRSDAYAADKLFATLDTTTRRL
FLPERGLIVISDTVGFIRDLPHTLVAAFRATLEETIQADLLLHVVDVSSSNRDVQISEVNKLLQEIGADTIPQILILNKI
DLIEQGSSENYMRDEYGRIARIHLSARTGAGFGYLYEALVEAFDQNLNKLSSIQQHP

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=191, Percent_Identity=37.17277486911, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310133118, Length=192, Percent_Identity=36.9791666666667, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI310124269, Length=173, Percent_Identity=38.150289017341, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124267, Length=173, Percent_Identity=38.150289017341, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124171, Length=173, Percent_Identity=38.150289017341, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310124169, Length=173, Percent_Identity=38.150289017341, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1790615, Length=354, Percent_Identity=55.0847457627119, Blast_Score=382, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17561038, Length=278, Percent_Identity=31.294964028777, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24650079, Length=329, Percent_Identity=31.0030395136778, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42272; Mature: 42272

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHDIGTAADNTAILVDINFGKNDKESLDELKELAYSDQLSIVAVVEGTRKQPDPATFIG
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEC
KGKVEEISQIVVQTQAAMVIFNHELSPIQQRNLSTALACRIIDRTSLILDIFAQRAKSHE
CCCHHHHHHHHHHHHHEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKLQVELAQLEYLSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLAKRVKFLKEKLA
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KLKQQRDVQRRARKRSEIMSVSIVGYTNAGKSTLFNRLVRSDAYAADKLFATLDTTTRRL
HHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHEE
FLPERGLIVISDTVGFIRDLPHTLVAAFRATLEETIQADLLLHVVDVSSSNRDVQISEVN
ECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEHHHHH
KLLQEIGADTIPQILILNKIDLIEQGSSENYMRDEYGRIARIHLSARTGAGFGYLYEALV
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHH
EAFDQNLNKLSSIQQHP
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNHDIGTAADNTAILVDINFGKNDKESLDELKELAYSDQLSIVAVVEGTRKQPDPATFIG
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEC
KGKVEEISQIVVQTQAAMVIFNHELSPIQQRNLSTALACRIIDRTSLILDIFAQRAKSHE
CCCHHHHHHHHHHHHHEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKLQVELAQLEYLSTRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLAKRVKFLKEKLA
CCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KLKQQRDVQRRARKRSEIMSVSIVGYTNAGKSTLFNRLVRSDAYAADKLFATLDTTTRRL
HHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHEE
FLPERGLIVISDTVGFIRDLPHTLVAAFRATLEETIQADLLLHVVDVSSSNRDVQISEVN
ECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEHHHHH
KLLQEIGADTIPQILILNKIDLIEQGSSENYMRDEYGRIARIHLSARTGAGFGYLYEALV
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHH
EAFDQNLNKLSSIQQHP
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]