Click here to switch to the map view.

The map label for this gene is hfq

Identifier: 114330964

GI number: 114330964

Start: 992145

End: 992387

Strand: Direct

Name: hfq

Synonym: Neut_0961

Alternate gene names: 114330964

Gene position: 992145-992387 (Clockwise)

Preceding gene: 114330963

Following gene: 114330965

Centisome position: 37.28

GC content: 40.33

Gene sequence:

>243_bases
GTGGGCGTTAAAGGACAGTTATTGCAAGATCCATTTTTGAATGTTTTGCGTAAGGAACATATTCCAGTCTCCATCTACCT
GGTCAACGGTATCAAGTTGCAGGGACATATTGATTCCTTTGATCAGTACGTGGTTTTATTGAGAAATTCTGTTACACAGA
TGGTTTATAAACATGCTATTTCTACTATAGTACCAGGTAAGGCAGTTTCAATTCCGGTGCCAGCTGAAACACTGCCCGAG
TAA

Upstream 100 bases:

>100_bases
TTTAGGATCTTGGCAAAAACACTGCCAGAACCAGTCAGTTTACCCATGAGGGTACTTACTTTAACCAAATAACTAGAAAT
TCAACCAGGGAGGGTAAACA

Downstream 100 bases:

>100_bases
GATGAATCATGACATCGGAACGGCAGCGGATAATACCGCAATATTAGTAGATATCAATTTTGGCAAAAATGATAAGGAAA
GTCTGGATGAGCTGAAAGAG

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MGVKGQLLQDPFLNVLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLRNSVTQMVYKHAISTIVPGKAVSIPVPAETLPE

Sequences:

>Translated_80_residues
MGVKGQLLQDPFLNVLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLRNSVTQMVYKHAISTIVPGKAVSIPVPAETLPE
>Mature_79_residues
GVKGQLLQDPFLNVLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLRNSVTQMVYKHAISTIVPGKAVSIPVPAETLPE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=68, Percent_Identity=75, Blast_Score=113, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_NITEC (Q0AHG1)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747186.1
- ProteinModelPortal:   Q0AHG1
- SMR:   Q0AHG1
- STRING:   Q0AHG1
- GeneID:   4273533
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0961
- NMPDR:   fig|335283.3.peg.1549
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- PhylomeDB:   Q0AHG1
- ProtClustDB:   PRK00395
- BioCyc:   NEUT335283:NEUT_0961-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 8866; Mature: 8734

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVKGQLLQDPFLNVLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLRNSVTQMVYKHAI
CCCCCCCCCCHHHHHHHHCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
STIVPGKAVSIPVPAETLPE
HHCCCCCEEECCCCHHCCCC
>Mature Secondary Structure 
GVKGQLLQDPFLNVLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLRNSVTQMVYKHAI
CCCCCCCCCHHHHHHHHCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
STIVPGKAVSIPVPAETLPE
HHCCCCCEEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA