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The map label for this gene is obgE

Identifier: 114330960

GI number: 114330960

Start: 987165

End: 988196

Strand: Direct

Name: obgE

Synonym: Neut_0957

Alternate gene names: 114330960

Gene position: 987165-988196 (Clockwise)

Preceding gene: 114330959

Following gene: 114330961

Centisome position: 37.1

GC content: 48.55

Gene sequence:

>1032_bases
ATGAAATATATAGATGAAGTAAAAATACAGGTCTTTGCAGGAGATGGCGGCAACGGTGTTGCCAGCTTTCGCCGTGAAAA
GTTTATTCCCAAAGGTGGACCGGATGGAGGAGATGGGGGCCGTGGCGGCAGTATCTATGCATTGGCGGATCACAACCTCA
ATACATTGATCGATTACCGTTTTACGCCAGTTTTTCGCGCAAAACGAGGAGAAAACGGACGTGGCTCTGATTGTTATGGC
AAAGGAGCAGAAGATATTGTATTGCGTATGCCGGTAGGTACAATCATAACCGACTATATGACAGGCGAGCTTGTGGCAGA
TCTCAAGCAAAATCAGCAGAAAGTGCTGCTGGCCAAAGGCGGTAAAGGAGGGTTGGGTAATCTCCATTTCAAATCCAGCA
CTAACCGTGCCCCCCGGCAATTTACTCATGGTGAGGCAGGAGAACAGTTTGAACTCAAGCTGGAGCTTAGGGTGCTGGCT
GATGTAGGATTGCTTGGATTACCGAATGCCGGTAAATCAACCTTGATCCGTGCCGTTTCTGCAGCGCGGCCGAAAGTGGC
TGATTACCCGTTTACTACGCTTTATCCCAATTTAGGGGTGGTGCGGGTCGATGCCGGGCGCAGTTTTATAATGGCGGATA
TTCCTGGCTTGATTGAAGGTGCTGCGGAAGGGGCCGGTCTCGGACACCGTTTTCTTAAACACCTCAGCCGCACTCATTTA
TTGCTGCATATTATTGATGTGGCTCCTTTTGATGAGAATATTGATCCTGTTCAATCAGCTAGGGCACTAGTAGACGAGCT
TCGCAAATTTGATGAAGTGCTTTATCGTAAACCACGCTGGTTAATATTTAATAAGGTAGATTTACTGCCTGAGGATGAGC
AGCAAGCTGTTTGCACGCATTTGCTGCAGGCGCTTGACTGGGAAGATCGCTGGTTTGCCATTTCTGCTCTAACTGGGAGA
GGGTGCCAGGCGCTGACCTATGCCATTATGGGATATCTGGAGCAACTACAGCCTGTTACCGAAGAAACTTGA

Upstream 100 bases:

>100_bases
AGCCCCATTGCTTGAATGGGGCTTTTTATTTTGTATAGTTTTTACCAGGATAAATTTTTCCGTCTGCAATCGCAATCGAA
ATAGTTGCTGCGGAGCACTC

Downstream 100 bases:

>100_bases
TTTTTATGACACGATCAATTCTGCAATCTGCACGCCGGATTATTGTAAAGGTTGGCAGCAGTCTGGTGACAAACGAAGGA
AGCGGCCTTGATCGTCAGGT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MKYIDEVKIQVFAGDGGNGVASFRREKFIPKGGPDGGDGGRGGSIYALADHNLNTLIDYRFTPVFRAKRGENGRGSDCYG
KGAEDIVLRMPVGTIITDYMTGELVADLKQNQQKVLLAKGGKGGLGNLHFKSSTNRAPRQFTHGEAGEQFELKLELRVLA
DVGLLGLPNAGKSTLIRAVSAARPKVADYPFTTLYPNLGVVRVDAGRSFIMADIPGLIEGAAEGAGLGHRFLKHLSRTHL
LLHIIDVAPFDENIDPVQSARALVDELRKFDEVLYRKPRWLIFNKVDLLPEDEQQAVCTHLLQALDWEDRWFAISALTGR
GCQALTYAIMGYLEQLQPVTEET

Sequences:

>Translated_343_residues
MKYIDEVKIQVFAGDGGNGVASFRREKFIPKGGPDGGDGGRGGSIYALADHNLNTLIDYRFTPVFRAKRGENGRGSDCYG
KGAEDIVLRMPVGTIITDYMTGELVADLKQNQQKVLLAKGGKGGLGNLHFKSSTNRAPRQFTHGEAGEQFELKLELRVLA
DVGLLGLPNAGKSTLIRAVSAARPKVADYPFTTLYPNLGVVRVDAGRSFIMADIPGLIEGAAEGAGLGHRFLKHLSRTHL
LLHIIDVAPFDENIDPVQSARALVDELRKFDEVLYRKPRWLIFNKVDLLPEDEQQAVCTHLLQALDWEDRWFAISALTGR
GCQALTYAIMGYLEQLQPVTEET
>Mature_343_residues
MKYIDEVKIQVFAGDGGNGVASFRREKFIPKGGPDGGDGGRGGSIYALADHNLNTLIDYRFTPVFRAKRGENGRGSDCYG
KGAEDIVLRMPVGTIITDYMTGELVADLKQNQQKVLLAKGGKGGLGNLHFKSSTNRAPRQFTHGEAGEQFELKLELRVLA
DVGLLGLPNAGKSTLIRAVSAARPKVADYPFTTLYPNLGVVRVDAGRSFIMADIPGLIEGAAEGAGLGHRFLKHLSRTHL
LLHIIDVAPFDENIDPVQSARALVDELRKFDEVLYRKPRWLIFNKVDLLPEDEQQAVCTHLLQALDWEDRWFAISALTGR
GCQALTYAIMGYLEQLQPVTEET

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=323, Percent_Identity=38.0804953560372, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI111955139, Length=292, Percent_Identity=34.2465753424658, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI111955063, Length=249, Percent_Identity=32.1285140562249, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=29.6296296296296, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4758796, Length=128, Percent_Identity=34.375, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789574, Length=341, Percent_Identity=58.6510263929619, Blast_Score=371, Evalue=1e-104,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=37, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=326, Percent_Identity=37.4233128834356, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17552324, Length=327, Percent_Identity=30.5810397553517, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=34.375, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=119, Percent_Identity=35.2941176470588, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=195, Percent_Identity=34.8717948717949, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=89, Percent_Identity=39.3258426966292, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321649, Length=151, Percent_Identity=29.1390728476821, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129375, Length=287, Percent_Identity=40.418118466899, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24585318, Length=296, Percent_Identity=35.472972972973, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24640873, Length=133, Percent_Identity=33.8345864661654, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640877, Length=133, Percent_Identity=33.8345864661654, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640875, Length=133, Percent_Identity=33.8345864661654, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_NITEC (Q0AHG5)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747182.1
- ProteinModelPortal:   Q0AHG5
- SMR:   Q0AHG5
- STRING:   Q0AHG5
- GeneID:   4272428
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0957
- NMPDR:   fig|335283.3.peg.1545
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- PhylomeDB:   Q0AHG5
- ProtClustDB:   PRK12299
- BioCyc:   NEUT335283:NEUT_0957-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 37663; Mature: 37663

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIDEVKIQVFAGDGGNGVASFRREKFIPKGGPDGGDGGRGGSIYALADHNLNTLIDYR
CCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEE
FTPVFRAKRGENGRGSDCYGKGAEDIVLRMPVGTIITDYMTGELVADLKQNQQKVLLAKG
CCEEEECCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
GKGGLGNLHFKSSTNRAPRQFTHGEAGEQFELKLELRVLADVGLLGLPNAGKSTLIRAVS
CCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AARPKVADYPFTTLYPNLGVVRVDAGRSFIMADIPGLIEGAAEGAGLGHRFLKHLSRTHL
HCCCCCCCCCCHHCCCCCCEEEECCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHE
LLHIIDVAPFDENIDPVQSARALVDELRKFDEVLYRKPRWLIFNKVDLLPEDEQQAVCTH
EHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHH
LLQALDWEDRWFAISALTGRGCQALTYAIMGYLEQLQPVTEET
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKYIDEVKIQVFAGDGGNGVASFRREKFIPKGGPDGGDGGRGGSIYALADHNLNTLIDYR
CCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEE
FTPVFRAKRGENGRGSDCYGKGAEDIVLRMPVGTIITDYMTGELVADLKQNQQKVLLAKG
CCEEEECCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
GKGGLGNLHFKSSTNRAPRQFTHGEAGEQFELKLELRVLADVGLLGLPNAGKSTLIRAVS
CCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCEEECCCCCHHHHHHHHH
AARPKVADYPFTTLYPNLGVVRVDAGRSFIMADIPGLIEGAAEGAGLGHRFLKHLSRTHL
HCCCCCCCCCCHHCCCCCCEEEECCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHE
LLHIIDVAPFDENIDPVQSARALVDELRKFDEVLYRKPRWLIFNKVDLLPEDEQQAVCTH
EHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHH
LLQALDWEDRWFAISALTGRGCQALTYAIMGYLEQLQPVTEET
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA