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The map label for this gene is nuoE [H]

Identifier: 114330929

GI number: 114330929

Start: 951491

End: 951979

Strand: Direct

Name: nuoE [H]

Synonym: Neut_0926

Alternate gene names: 114330929

Gene position: 951491-951979 (Clockwise)

Preceding gene: 114330928

Following gene: 114330930

Centisome position: 35.76

GC content: 39.88

Gene sequence:

>489_bases
ATGAGTTCGCTGATGTTAAGCATGGAAGCTCTAAAAAAGATTGATCGGGAAATTGCCAAATATCCCACGGATAAAAAGCA
GTCGGCTGTCATGTCTGCGCTGGCCATTGCTCAAGATGAAAAAGGCTGGTTGGCAACTGAAACAATGGATTTTATTGCAA
ACTATTTAGAGATGCCTGCAATTGCCGTCTATGAAGTTGCTACTTTTTACAATATGTATAACCTGAAGCCGATTGGAAAA
TACAAATTGACTGTTTGTACCAATTTGCCTTGTGCGTTATCAGGTAGTAATCAGACTGTAGATTATCTTAAGAAGAAACT
TGACATAGGGTTCAATGAAACAACTGTGGATGGATTGTTTACCCTCAAGGAAGGCGAGTGTATGGGAGCTTGTGGAGATG
CGCCAGTACTTCTGGTTAATAACAAGCGTATGTGCAGCTTTATGACTGAGGATCAAATAGACAAATTGCTTGAGGAATTA
AAGAGATGA

Upstream 100 bases:

>100_bases
CACATTTAGCTGCAATGGATGAGATGGCTCGAGGGCATATGATTGCTGATCTTGTGGCAATTATTGGTACCCAGGATATA
GTGTTTGGTGAAATAGATAG

Downstream 100 bases:

>100_bases
CTCAACCTACTCAAGTCATCATGGCGGGTGTCGATTCTGCAGATCCAAATAATTGGCGGTTAAAAAGTTATTTAAAACGT
GACGGATATGTTGCGTTAAA

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MSSLMLSMEALKKIDREIAKYPTDKKQSAVMSALAIAQDEKGWLATETMDFIANYLEMPAIAVYEVATFYNMYNLKPIGK
YKLTVCTNLPCALSGSNQTVDYLKKKLDIGFNETTVDGLFTLKEGECMGACGDAPVLLVNNKRMCSFMTEDQIDKLLEEL
KR

Sequences:

>Translated_162_residues
MSSLMLSMEALKKIDREIAKYPTDKKQSAVMSALAIAQDEKGWLATETMDFIANYLEMPAIAVYEVATFYNMYNLKPIGK
YKLTVCTNLPCALSGSNQTVDYLKKKLDIGFNETTVDGLFTLKEGECMGACGDAPVLLVNNKRMCSFMTEDQIDKLLEEL
KR
>Mature_161_residues
SSLMLSMEALKKIDREIAKYPTDKKQSAVMSALAIAQDEKGWLATETMDFIANYLEMPAIAVYEVATFYNMYNLKPIGKY
KLTVCTNLPCALSGSNQTVDYLKKKLDIGFNETTVDGLFTLKEGECMGACGDAPVLLVNNKRMCSFMTEDQIDKLLEELK
R

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=156, Percent_Identity=42.9487179487179, Blast_Score=139, Evalue=2e-33,
Organism=Escherichia coli, GI1788621, Length=159, Percent_Identity=31.4465408805031, Blast_Score=90, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17561328, Length=141, Percent_Identity=43.2624113475177, Blast_Score=128, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18859877, Length=156, Percent_Identity=39.7435897435897, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21355353, Length=156, Percent_Identity=35.8974358974359, Blast_Score=111, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18149; Mature: 18018

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
9.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLMLSMEALKKIDREIAKYPTDKKQSAVMSALAIAQDEKGWLATETMDFIANYLEMPA
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCH
IAVYEVATFYNMYNLKPIGKYKLTVCTNLPCALSGSNQTVDYLKKKLDIGFNETTVDGLF
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHCCCCCCCCCCEEE
TLKEGECMGACGDAPVLLVNNKRMCSFMTEDQIDKLLEELKR
EEECCCCCCCCCCCCEEEECCCHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSLMLSMEALKKIDREIAKYPTDKKQSAVMSALAIAQDEKGWLATETMDFIANYLEMPA
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCH
IAVYEVATFYNMYNLKPIGKYKLTVCTNLPCALSGSNQTVDYLKKKLDIGFNETTVDGLF
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCHHHHHHHHHCCCCCCCCCCEEE
TLKEGECMGACGDAPVLLVNNKRMCSFMTEDQIDKLLEELKR
EEECCCCCCCCCCCCEEEECCCHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]