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The map label for this gene is argJ [H]

Identifier: 114330670

GI number: 114330670

Start: 665194

End: 666423

Strand: Reverse

Name: argJ [H]

Synonym: Neut_0655

Alternate gene names: 114330670

Gene position: 666423-665194 (Counterclockwise)

Preceding gene: 114330678

Following gene: 114330669

Centisome position: 25.04

GC content: 53.66

Gene sequence:

>1230_bases
ATGCCAGTCAACATTCCACCGCTACTACCTGAACAGCTGCTGCCGATCCAGGGCATATCATTGGGGACGGCAGAAGCAGG
CATCAAGCGATCCGGCCGAAAAGACCTGCTGGTCATCAAGCTTGCCGAAAACACACAAGTTGCCGGTGTTTTCACTAAAA
ACCGGTTCTGTGCCGCACCTGTTACGGTAGCCAAATCACATCTTGCAGCCCTTTTACCGACTCGCGCACTGGTGATCAAT
ACTGGCAATGCCAATGCCGGCACCGGCCAATCCGGTATTGATCACGCATACGCCACCTGCGCCGCGCTGGCCGGGCTCAT
TGGCTGCCAGGTACAGCAGATCTTGCCATTTTCCACCGGCGTCATCATGGAGCCACTGCCGGTAGAAAAAATTACTGCCT
GCCTGCCCCAGGCAGTGGCAAACCTGGTTCCGGACAACTGGTTTGCTGCTGCTCAGGCAATCATGACGACCGACATTGTG
CCCAAGGGCGTTTCCCGCCAGATTCAATTGGGCGGAACGACCGTCACCATCACCGGCATCACCAAAGGTTCGGGCATGAT
CCATCCGAACATGGCCACCATGCTTAGTTATATCGCTACGGATGCAGCTATTACGCAACCCTTGCTGAACGATTTGGTAC
ACCACACGGCCAATCAATCCTTCAACTGCATTACCGTAGATGGCGACACCTCCACTAACGACGCATTGATCCTGATGGCC
ACCGGACAGGCGAAGCACAACCTGATCACTACATCAACCGACCTCGGATTTATCACGCTGCAGGCGGCCATTACCGAAGT
GGCCATTCTGCTTGCCCAGATGATTGTGCGCGATGGCGAAGGTGCAACCAAATTCATCACCGTGCAAGTAGAAGGTGGCA
GGACAGCGGAAGAATGCAGCAAGGTCGCCTATGCCATCGCACATTCCCCGCTGATCAAAACGGCCTGCTTCGCATCCGAT
CCCAATCTGGGACGAATTCTGGCTGCCATCGGTTATGCCGGCATTGAGGATCTGGATGTCAATCTTGTTCAGCTTTATCT
GGAAAATACCCTGGTCGCCGAACACGGTGGCCGTGCTGCCAGCTACCGTGAAAAAGAAGGGCAACGTATCATGCAGGCAC
CAGAAATTACTATTCAGGTAAAACTCAATCGGGGAAATGCAGCCACCACAATATGGACCTGCGATCTTTCCTATGATTAC
GTAAAAATCAATGCCGATTACCGCAGCTGA

Upstream 100 bases:

>100_bases
AACTCCATTCATAGTTTTAGATAATGGAATAATTCCAGGCAACCCGGCGATTTCCTGCGGGATAGGTTACGATAACGTTT
TTTCTTACAGACTCTCATTC

Downstream 100 bases:

>100_bases
TATGAATGATTCCGAACTGTTTTTCCAACGCTTAGACCAACTGTTAACGCGCATTGAGGACATCCTCCCTACCCGGATAC
AGCACGCTGATCTTGACGCA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPVNIPPLLPEQLLPIQGISLGTAEAGIKRSGRKDLLVIKLAENTQVAGVFTKNRFCAAPVTVAKSHLAALLPTRALVIN
TGNANAGTGQSGIDHAYATCAALAGLIGCQVQQILPFSTGVIMEPLPVEKITACLPQAVANLVPDNWFAAAQAIMTTDIV
PKGVSRQIQLGGTTVTITGITKGSGMIHPNMATMLSYIATDAAITQPLLNDLVHHTANQSFNCITVDGDTSTNDALILMA
TGQAKHNLITTSTDLGFITLQAAITEVAILLAQMIVRDGEGATKFITVQVEGGRTAEECSKVAYAIAHSPLIKTACFASD
PNLGRILAAIGYAGIEDLDVNLVQLYLENTLVAEHGGRAASYREKEGQRIMQAPEITIQVKLNRGNAATTIWTCDLSYDY
VKINADYRS

Sequences:

>Translated_409_residues
MPVNIPPLLPEQLLPIQGISLGTAEAGIKRSGRKDLLVIKLAENTQVAGVFTKNRFCAAPVTVAKSHLAALLPTRALVIN
TGNANAGTGQSGIDHAYATCAALAGLIGCQVQQILPFSTGVIMEPLPVEKITACLPQAVANLVPDNWFAAAQAIMTTDIV
PKGVSRQIQLGGTTVTITGITKGSGMIHPNMATMLSYIATDAAITQPLLNDLVHHTANQSFNCITVDGDTSTNDALILMA
TGQAKHNLITTSTDLGFITLQAAITEVAILLAQMIVRDGEGATKFITVQVEGGRTAEECSKVAYAIAHSPLIKTACFASD
PNLGRILAAIGYAGIEDLDVNLVQLYLENTLVAEHGGRAASYREKEGQRIMQAPEITIQVKLNRGNAATTIWTCDLSYDY
VKINADYRS
>Mature_408_residues
PVNIPPLLPEQLLPIQGISLGTAEAGIKRSGRKDLLVIKLAENTQVAGVFTKNRFCAAPVTVAKSHLAALLPTRALVINT
GNANAGTGQSGIDHAYATCAALAGLIGCQVQQILPFSTGVIMEPLPVEKITACLPQAVANLVPDNWFAAAQAIMTTDIVP
KGVSRQIQLGGTTVTITGITKGSGMIHPNMATMLSYIATDAAITQPLLNDLVHHTANQSFNCITVDGDTSTNDALILMAT
GQAKHNLITTSTDLGFITLQAAITEVAILLAQMIVRDGEGATKFITVQVEGGRTAEECSKVAYAIAHSPLIKTACFASDP
NLGRILAAIGYAGIEDLDVNLVQLYLENTLVAEHGGRAASYREKEGQRIMQAPEITIQVKLNRGNAATTIWTCDLSYDYV
KINADYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=416, Percent_Identity=38.9423076923077, Blast_Score=248, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 43242; Mature: 43111

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVNIPPLLPEQLLPIQGISLGTAEAGIKRSGRKDLLVIKLAENTQVAGVFTKNRFCAAP
CCCCCCCCCHHHCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCEEECC
VTVAKSHLAALLPTRALVINTGNANAGTGQSGIDHAYATCAALAGLIGCQVQQILPFSTG
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIMEPLPVEKITACLPQAVANLVPDNWFAAAQAIMTTDIVPKGVSRQIQLGGTTVTITGI
CEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEEE
TKGSGMIHPNMATMLSYIATDAAITQPLLNDLVHHTANQSFNCITVDGDTSTNDALILMA
ECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEE
TGQAKHNLITTSTDLGFITLQAAITEVAILLAQMIVRDGEGATKFITVQVEGGRTAEECS
CCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHH
KVAYAIAHSPLIKTACFASDPNLGRILAAIGYAGIEDLDVNLVQLYLENTLVAEHGGRAA
HHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHEEEHHHHEEEECCCCCCC
SYREKEGQRIMQAPEITIQVKLNRGNAATTIWTCDLSYDYVKINADYRS
CCHHHHCCHHHCCCCEEEEEEEECCCCEEEEEEEECCEEEEEEEECCCC
>Mature Secondary Structure 
PVNIPPLLPEQLLPIQGISLGTAEAGIKRSGRKDLLVIKLAENTQVAGVFTKNRFCAAP
CCCCCCCCHHHCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCEEECC
VTVAKSHLAALLPTRALVINTGNANAGTGQSGIDHAYATCAALAGLIGCQVQQILPFSTG
HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIMEPLPVEKITACLPQAVANLVPDNWFAAAQAIMTTDIVPKGVSRQIQLGGTTVTITGI
CEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEEE
TKGSGMIHPNMATMLSYIATDAAITQPLLNDLVHHTANQSFNCITVDGDTSTNDALILMA
ECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEE
TGQAKHNLITTSTDLGFITLQAAITEVAILLAQMIVRDGEGATKFITVQVEGGRTAEECS
CCCCCCCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHH
KVAYAIAHSPLIKTACFASDPNLGRILAAIGYAGIEDLDVNLVQLYLENTLVAEHGGRAA
HHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHEEEHHHHEEEECCCCCCC
SYREKEGQRIMQAPEITIQVKLNRGNAATTIWTCDLSYDYVKINADYRS
CCHHHHCCHHHCCCCEEEEEEEECCCCEEEEEEEECCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]