Click here to switch to the map view.

The map label for this gene is xanB [H]

Identifier: 114330633

GI number: 114330633

Start: 628058

End: 629509

Strand: Reverse

Name: xanB [H]

Synonym: Neut_0618

Alternate gene names: 114330633

Gene position: 629509-628058 (Counterclockwise)

Preceding gene: 114330634

Following gene: 114330632

Centisome position: 23.66

GC content: 50.9

Gene sequence:

>1452_bases
ATGAAACATTCCCTTACCCCAGTCATTCTTTCCGGTGGCTCAGGCACACGGCTATGGCCACTTTCGCGCCAGCAATATCC
CAAGCAATTACTGCCGCTGGTTGATCAGCATTCCCTGCTGCAGGAAACCGTGCGCCGCCTGGATGGGCTGGATGATATCG
TTATTCAACCGCCCATCATTGTGTGCAACGAGGAGTACCGTTTTGTGATTGCAGAGCAGCTTCGGCTTATCGGTAAAACC
GGCAAGATCATTCTTGAACCATTCGGGCGGAATACTGCGCCTGCTCTGACAATCGCGGCATTAGCTGCTATACAAGAAGG
GAATGATCCGATCTTGCTGGTGATGCCATCTGACCATGTCATCACAGATATAGCTGCCTTTCAGACAGCTGTTCACAAGG
GTATACTGCTTGCCGAAAGCGGTATGTTGGTTACTTTTGGTATCACGCCTGATACGCCGGAAACCGGTTATGGCTATATT
CAGTACGGTACTGCACTACACGAACCGGGTACTTTCCAGATCTCCCGCTTTGTTGAAAAACCAGATCTGGTCACGGCACA
GAATTATCTGCAAGAAGGTTCCTATTTATGGAACAGCGGCATGTTCATGATGCGCACATCTGTCTGGCTTGCTGCCATTG
ATACCTGCCGTCAAAATATTCTGGATGCCTGCCGCGCTGCATGGCAGCCGGAATCAGTAGATGGTGATTTTCACCGGATT
GATAAAACTGCCTTTGCTGCCTGCCCCGGCGATTCCATTGATTATGCCGTGATGGAATCACTTTCCACTCATCCGGATAC
CTTGCCGCCAGGCGCAATCATTCCGCTTTCAGCCGGATGGTCGGATATCGGCGCGTGGGATGCGTTGTGGCACACCCTGC
CAAAGGATGAATCAGGCAACGTCGTACGCGGCGATGTGTTATTGCAAGAGTGTTATAACACTCTTGCATTCTCCGAGCAT
CGACTGGTTGCTTGTATCGGCGTAAATAACGTAGTCATTGTGGAAACTTCTGACGCGATTCTGGTTGCACATCAGGACAA
AACACAGGAAGTCAAACATATCGTTGACACCCTAAGGCAGAAAAACCGGCCGGAAACCCGCTCACATCGCAAAATATACC
GCCCGTGGGGCTGGTACGATTCGATCGATACAGGTGAACGCTTCCAGGTCAAGCGCATTGTTGTCAACCCTGGCGCCGCA
TTATCATTACAAATGCACCATCACCGCGCCGAACACTGGATTGTGGTGCGTGGAACCGCACAGGTTACCCGGGCAGACAA
AACCTTTCTGGTCAGTGAAAATGAATCCACTTTTATTCCGCTGGGGACACCGCACCGGCTGGAAAACCCAGGACGAGTGC
CGCTGGAAATGATTGAAGTCCAGTCCGGTTCCTATCTGGGAGAAGATGATATCGTCCGGTTTGAGGATAAATACGGCAGA
AAGGAAAGTTAA

Upstream 100 bases:

>100_bases
CGTGGAAATACTGACCAGAGAATTGGATCGCCCCTGAATTCAAAATTTCGAATGGTCAGCAAAAATCTGCCCTATTCTTC
ATAACCAATCTGATGCAAGC

Downstream 100 bases:

>100_bases
CAGGCTCGAGCCAGGCTGATACAGCCCGCGATCAGGCAAAGCCACCCGGGAAATTGCTCTGGCAGTCAAGTATAATGCCG
TTTTCAAAGACTTTATTTAA

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MKHSLTPVILSGGSGTRLWPLSRQQYPKQLLPLVDQHSLLQETVRRLDGLDDIVIQPPIIVCNEEYRFVIAEQLRLIGKT
GKIILEPFGRNTAPALTIAALAAIQEGNDPILLVMPSDHVITDIAAFQTAVHKGILLAESGMLVTFGITPDTPETGYGYI
QYGTALHEPGTFQISRFVEKPDLVTAQNYLQEGSYLWNSGMFMMRTSVWLAAIDTCRQNILDACRAAWQPESVDGDFHRI
DKTAFAACPGDSIDYAVMESLSTHPDTLPPGAIIPLSAGWSDIGAWDALWHTLPKDESGNVVRGDVLLQECYNTLAFSEH
RLVACIGVNNVVIVETSDAILVAHQDKTQEVKHIVDTLRQKNRPETRSHRKIYRPWGWYDSIDTGERFQVKRIVVNPGAA
LSLQMHHHRAEHWIVVRGTAQVTRADKTFLVSENESTFIPLGTPHRLENPGRVPLEMIEVQSGSYLGEDDIVRFEDKYGR
KES

Sequences:

>Translated_483_residues
MKHSLTPVILSGGSGTRLWPLSRQQYPKQLLPLVDQHSLLQETVRRLDGLDDIVIQPPIIVCNEEYRFVIAEQLRLIGKT
GKIILEPFGRNTAPALTIAALAAIQEGNDPILLVMPSDHVITDIAAFQTAVHKGILLAESGMLVTFGITPDTPETGYGYI
QYGTALHEPGTFQISRFVEKPDLVTAQNYLQEGSYLWNSGMFMMRTSVWLAAIDTCRQNILDACRAAWQPESVDGDFHRI
DKTAFAACPGDSIDYAVMESLSTHPDTLPPGAIIPLSAGWSDIGAWDALWHTLPKDESGNVVRGDVLLQECYNTLAFSEH
RLVACIGVNNVVIVETSDAILVAHQDKTQEVKHIVDTLRQKNRPETRSHRKIYRPWGWYDSIDTGERFQVKRIVVNPGAA
LSLQMHHHRAEHWIVVRGTAQVTRADKTFLVSENESTFIPLGTPHRLENPGRVPLEMIEVQSGSYLGEDDIVRFEDKYGR
KES
>Mature_483_residues
MKHSLTPVILSGGSGTRLWPLSRQQYPKQLLPLVDQHSLLQETVRRLDGLDDIVIQPPIIVCNEEYRFVIAEQLRLIGKT
GKIILEPFGRNTAPALTIAALAAIQEGNDPILLVMPSDHVITDIAAFQTAVHKGILLAESGMLVTFGITPDTPETGYGYI
QYGTALHEPGTFQISRFVEKPDLVTAQNYLQEGSYLWNSGMFMMRTSVWLAAIDTCRQNILDACRAAWQPESVDGDFHRI
DKTAFAACPGDSIDYAVMESLSTHPDTLPPGAIIPLSAGWSDIGAWDALWHTLPKDESGNVVRGDVLLQECYNTLAFSEH
RLVACIGVNNVVIVETSDAILVAHQDKTQEVKHIVDTLRQKNRPETRSHRKIYRPWGWYDSIDTGERFQVKRIVVNPGAA
LSLQMHHHRAEHWIVVRGTAQVTRADKTFLVSENESTFIPLGTPHRLENPGRVPLEMIEVQSGSYLGEDDIVRFEDKYGR
KES

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=485, Percent_Identity=50.5154639175258, Blast_Score=491, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 53914; Mature: 53914

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHSLTPVILSGGSGTRLWPLSRQQYPKQLLPLVDQHSLLQETVRRLDGLDDIVIQPPII
CCCCCCEEEEECCCCCEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEE
VCNEEYRFVIAEQLRLIGKTGKIILEPFGRNTAPALTIAALAAIQEGNDPILLVMPSDHV
EECCCCEEHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCH
ITDIAAFQTAVHKGILLAESGMLVTFGITPDTPETGYGYIQYGTALHEPGTFQISRFVEK
HHHHHHHHHHHHCCEEEECCCEEEEEECCCCCCCCCCCEEEECCEECCCCCEEHHHHHCC
PDLVTAQNYLQEGSYLWNSGMFMMRTSVWLAAIDTCRQNILDACRAAWQPESVDGDFHRI
CCCCHHHHHHHCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DKTAFAACPGDSIDYAVMESLSTHPDTLPPGAIIPLSAGWSDIGAWDALWHTLPKDESGN
CHHHEEECCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCCCC
VVRGDVLLQECYNTLAFSEHRLVACIGVNNVVIVETSDAILVAHQDKTQEVKHIVDTLRQ
EEEHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCEEEEEECCHHHHHHHHHHHHHH
KNRPETRSHRKIYRPWGWYDSIDTGERFQVKRIVVNPGAALSLQMHHHRAEHWIVVRGTA
CCCCCCHHCCEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCEEEEEECCC
QVTRADKTFLVSENESTFIPLGTPHRLENPGRVPLEMIEVQSGSYLGEDDIVRFEDKYGR
EEEECCCEEEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEHHCCCC
KES
CCC
>Mature Secondary Structure
MKHSLTPVILSGGSGTRLWPLSRQQYPKQLLPLVDQHSLLQETVRRLDGLDDIVIQPPII
CCCCCCEEEEECCCCCEEECCCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEE
VCNEEYRFVIAEQLRLIGKTGKIILEPFGRNTAPALTIAALAAIQEGNDPILLVMPSDHV
EECCCCEEHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCH
ITDIAAFQTAVHKGILLAESGMLVTFGITPDTPETGYGYIQYGTALHEPGTFQISRFVEK
HHHHHHHHHHHHCCEEEECCCEEEEEECCCCCCCCCCCEEEECCEECCCCCEEHHHHHCC
PDLVTAQNYLQEGSYLWNSGMFMMRTSVWLAAIDTCRQNILDACRAAWQPESVDGDFHRI
CCCCHHHHHHHCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DKTAFAACPGDSIDYAVMESLSTHPDTLPPGAIIPLSAGWSDIGAWDALWHTLPKDESGN
CHHHEEECCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCCCCCC
VVRGDVLLQECYNTLAFSEHRLVACIGVNNVVIVETSDAILVAHQDKTQEVKHIVDTLRQ
EEEHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEECCCEEEEEECCHHHHHHHHHHHHHH
KNRPETRSHRKIYRPWGWYDSIDTGERFQVKRIVVNPGAALSLQMHHHRAEHWIVVRGTA
CCCCCCHHCCEEECCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCEEEEEECCC
QVTRADKTFLVSENESTFIPLGTPHRLENPGRVPLEMIEVQSGSYLGEDDIVRFEDKYGR
EEEECCCEEEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEHHCCCC
KES
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]