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The map label for this gene is ctaA

Identifier: 114330603

GI number: 114330603

Start: 595605

End: 596675

Strand: Direct

Name: ctaA

Synonym: Neut_0588

Alternate gene names: 114330603

Gene position: 595605-596675 (Clockwise)

Preceding gene: 114330602

Following gene: 114330604

Centisome position: 22.38

GC content: 43.98

Gene sequence:

>1071_bases
ATGCAAACAAATTCATCTAACTCCGTTCCTTCGGCAATTTCTGATAAATATACTCAAAATCATATGCCTATTGCTATCTG
GTTGCTGATTTGCTGTGCGTTGGTGTTTGCCATGATTGTTGTGGGTGGAGTAACGCGTCTGACAGGTTCCGGGCTATCGA
TCGTTGAATGGAAGCCAATAGTTGGAACGATTCCACCTATTGGCCAGGAAGATTGGGAAGTATTGCTGGAGAAGTACCGT
CAGATACCTCAATACGAACAAGTTAATAAAGGTATGACGCTGGATGAATTCAAGGGAATATTCTGGTGGGAATATTTTCA
TCGTTTGCTTGGTCGCCTGATTGGTCTGGTTTATTTCATACCATTTGTCTATTTCATGGTGCGCAAACGGATTGATCGTT
TACTTGGTTTAAAGCTGCTGGGTATATTCGCGCTTGGTGCTTTGCAAGGGTTAATGGGCTGGTATATGGTTATGAGTGGA
CTGGCAGATAATGTTTATGTCAGTCAGTATCGGCTGACTGCACACCTTGGTCTCGCTTTTGTTATTTATGCTGCTATGTT
CTGGGTGGCTACCGGATTGATTTCTCCCTTAAATACTCATTTGTCAGACCCGGTATCCGTACATAAACTTAAAAAGTTTG
CCTGGATGCTGACTGGACTGATATTCGTTATGGTATTGTCCGGAGGATTGGTAGCGGGTATTCATGCCGGGAGGGCGTAT
AACACATTTCCCTTGATGGACGGCTTTCTGATTCCTCCCGCTATGTTTGTGCTGGAACCTTGGTATCGAAACTTTTTTGA
TAACATCACTACAGTACAATTTGACCACCGCTTGATTGCCTGGTTGCTTATTTTTTCTATACCATGGTTCTGGTTCAAGG
CAAAACAGTTATCATTGTCTTATTCTGGTCGCTTGGCTTGTCATCTCCTGCTGTTGATGTTGCTCATTCAAGCAGGGCTT
GGGATTACGACGTTATTATTGTCGGTTCCCCTGACGTTTGCTACAGCACACCAGGCTGGTGCTGTGCTGTTATTCACTGC
TGCATTGTGGGTTTGTCGTAAGCTATCCTGA

Upstream 100 bases:

>100_bases
GGGAAAAAAGCAATACGATAAACGTGAAAGTGAGAAACGTAAAGAATGGGAACGTGATAAGCAGCGCTTGTTGCGTATGC
GCCATTCCTGATTAATATTT

Downstream 100 bases:

>100_bases
CGGTAAATATGTGTTTTTTCTAATGGTGATACGCCTCTTTTTAGTAGATGAAACCTTGGGAAAGAATCAATAACCGGTAC
AAGAGAATATGCTGATGGAA

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MQTNSSNSVPSAISDKYTQNHMPIAIWLLICCALVFAMIVVGGVTRLTGSGLSIVEWKPIVGTIPPIGQEDWEVLLEKYR
QIPQYEQVNKGMTLDEFKGIFWWEYFHRLLGRLIGLVYFIPFVYFMVRKRIDRLLGLKLLGIFALGALQGLMGWYMVMSG
LADNVYVSQYRLTAHLGLAFVIYAAMFWVATGLISPLNTHLSDPVSVHKLKKFAWMLTGLIFVMVLSGGLVAGIHAGRAY
NTFPLMDGFLIPPAMFVLEPWYRNFFDNITTVQFDHRLIAWLLIFSIPWFWFKAKQLSLSYSGRLACHLLLLMLLIQAGL
GITTLLLSVPLTFATAHQAGAVLLFTAALWVCRKLS

Sequences:

>Translated_356_residues
MQTNSSNSVPSAISDKYTQNHMPIAIWLLICCALVFAMIVVGGVTRLTGSGLSIVEWKPIVGTIPPIGQEDWEVLLEKYR
QIPQYEQVNKGMTLDEFKGIFWWEYFHRLLGRLIGLVYFIPFVYFMVRKRIDRLLGLKLLGIFALGALQGLMGWYMVMSG
LADNVYVSQYRLTAHLGLAFVIYAAMFWVATGLISPLNTHLSDPVSVHKLKKFAWMLTGLIFVMVLSGGLVAGIHAGRAY
NTFPLMDGFLIPPAMFVLEPWYRNFFDNITTVQFDHRLIAWLLIFSIPWFWFKAKQLSLSYSGRLACHLLLLMLLIQAGL
GITTLLLSVPLTFATAHQAGAVLLFTAALWVCRKLS
>Mature_356_residues
MQTNSSNSVPSAISDKYTQNHMPIAIWLLICCALVFAMIVVGGVTRLTGSGLSIVEWKPIVGTIPPIGQEDWEVLLEKYR
QIPQYEQVNKGMTLDEFKGIFWWEYFHRLLGRLIGLVYFIPFVYFMVRKRIDRLLGLKLLGIFALGALQGLMGWYMVMSG
LADNVYVSQYRLTAHLGLAFVIYAAMFWVATGLISPLNTHLSDPVSVHKLKKFAWMLTGLIFVMVLSGGLVAGIHAGRAY
NTFPLMDGFLIPPAMFVLEPWYRNFFDNITTVQFDHRLIAWLLIFSIPWFWFKAKQLSLSYSGRLACHLLLLMLLIQAGL
GITTLLLSVPLTFATAHQAGAVLLFTAALWVCRKLS

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=354, Percent_Identity=40.9604519774011, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI17921987, Length=317, Percent_Identity=39.7476340694006, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17536069, Length=359, Percent_Identity=36.2116991643454, Blast_Score=220, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320989, Length=378, Percent_Identity=36.7724867724868, Blast_Score=225, Evalue=8e-60,
Organism=Drosophila melanogaster, GI19922860, Length=344, Percent_Identity=37.7906976744186, Blast_Score=225, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_NITEC (Q0AIG6)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746825.1
- STRING:   Q0AIG6
- GeneID:   4272703
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0588
- NMPDR:   fig|335283.3.peg.1462
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- PhylomeDB:   Q0AIG6
- ProtClustDB:   CLSK2758227
- BioCyc:   NEUT335283:NEUT_0588-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 40163; Mature: 40163

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: BINDING 337-337

Signals:

None

Transmembrane regions:

HASH(0x95299a4)-; HASH(0x11c8f2d4)-; HASH(0x138bd090)-; HASH(0x106f42f0)-; HASH(0x138213c0)-; HASH(0x10d90f84)-; HASH(0x12d0a8a8)-; HASH(0x40417bec)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTNSSNSVPSAISDKYTQNHMPIAIWLLICCALVFAMIVVGGVTRLTGSGLSIVEWKPI
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEECCCC
VGTIPPIGQEDWEVLLEKYRQIPQYEQVNKGMTLDEFKGIFWWEYFHRLLGRLIGLVYFI
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFVYFMVRKRIDRLLGLKLLGIFALGALQGLMGWYMVMSGLADNVYVSQYRLTAHLGLAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VIYAAMFWVATGLISPLNTHLSDPVSVHKLKKFAWMLTGLIFVMVLSGGLVAGIHAGRAY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
NTFPLMDGFLIPPAMFVLEPWYRNFFDNITTVQFDHRLIAWLLIFSIPWFWFKAKQLSLS
CCCCCCCCHHHCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YSGRLACHLLLLMLLIQAGLGITTLLLSVPLTFATAHQAGAVLLFTAALWVCRKLS
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MQTNSSNSVPSAISDKYTQNHMPIAIWLLICCALVFAMIVVGGVTRLTGSGLSIVEWKPI
CCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCEEEECCCC
VGTIPPIGQEDWEVLLEKYRQIPQYEQVNKGMTLDEFKGIFWWEYFHRLLGRLIGLVYFI
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
PFVYFMVRKRIDRLLGLKLLGIFALGALQGLMGWYMVMSGLADNVYVSQYRLTAHLGLAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VIYAAMFWVATGLISPLNTHLSDPVSVHKLKKFAWMLTGLIFVMVLSGGLVAGIHAGRAY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
NTFPLMDGFLIPPAMFVLEPWYRNFFDNITTVQFDHRLIAWLLIFSIPWFWFKAKQLSLS
CCCCCCCCHHHCHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YSGRLACHLLLLMLLIQAGLGITTLLLSVPLTFATAHQAGAVLLFTAALWVCRKLS
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA