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The map label for this gene is estA [H]

Identifier: 114330552

GI number: 114330552

Start: 556619

End: 557626

Strand: Direct

Name: estA [H]

Synonym: Neut_0534

Alternate gene names: 114330552

Gene position: 556619-557626 (Clockwise)

Preceding gene: 114330550

Following gene: 114330554

Centisome position: 20.92

GC content: 51.88

Gene sequence:

>1008_bases
ATGGGTGTGCTTTTCCTGGCCTTCATGTTGTCCGGAGCTGTCTGGGCAACGCCGTTTACCAGCCTGTACGCGTTTGGCGA
TAGTCTCTCGGATGGCGGTAACAGCCCGACTGCGGTAACGAGTATTTACAAGCTGCTGGGAAATAATTGTGATCCCACCC
ATCCCTGTCCACCTTATGTGGGCGGGCATTACTCCAATGGACCGGTAGCGGTTGAATATCTGGCAAATTCAATCCTGCCT
GGTGGCGCTAATTCAGGCAATTTTTTTAATTTCTCCGTCGCCGGAGCAACCAGCGGTATCGGTAACTATGGTGATAGAGG
GTCTGCAACCTCATCCGGCATTTTCGGATTACCTGGCATTAGTCTGGAAATTGAAGGTTATCTGCTTGCTTCGGGAGGCG
TGGCTGATCCGGATGCGTTGTATTTTGTCTGGGGTGGAGCAAATGATTTTCTGACATTAGATTCCCCCACTGCTGCAGCG
CAGAATATCGCAGCCAATGTAGACAAACTCATGGCGGCTGGAGCCACTCATTTTTTTGTGCCCAACCTGCCTGATCTGGG
CCTGACACCGCTGGCTGCAGAAGGAAATGTGCAAGGGCTGGCCACATTATTCTCCACCACGTTTAATACGGCGCTGTCTT
CCGAGTTGGCAGCGCTGGGTACGCAGTTTCCTGTTGCTGAAATTCTCCAATTTGATACCTATTCCTTTTTCAATCGGATT
GTTGGTGACCCGGCTGTGTATGGTTTTACCAATGCACAGGCAAGCTGCCTGGCTTTTCAGGCAGGAGGGGTGCAATGCAG
CAACCCGGATCAATACATATACTGGGATGACCTGCACCCTACCACGCAAGCGCACGCTCTGTTTGGTTCTGTTTTTGCCC
GGGCCATCCCTGTGCCGGGAACACTTTTTTTGCTGATGCTGGGCTGGCTGATACTTGTTTTTGCGCGCGGGAACTGGATT
TGCAAGAACCTGGCCAGGCCAGTTAATTCCATGGAACTGGTTGGCTGA

Upstream 100 bases:

>100_bases
CATTCCAGAGTTGTGCAAAGGTTTCCAGGGATTCAAAATGCATACAGTAGTATCTTTTTCAATCAATCTGCCATGAGGAG
AAATTGTGAAAAAACTGATA

Downstream 100 bases:

>100_bases
TTGCCGGGCTCTGTTTGAATCTGGTGGTGATGCAGGGCGGGCAAGCATAGTGCATCACCTGCAAACTACCGGGTTATTTC
GAGTGCTTCCCGGTAGCTTT

Product: lipolytic enzyme, G-D-S-L family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MGVLFLAFMLSGAVWATPFTSLYAFGDSLSDGGNSPTAVTSIYKLLGNNCDPTHPCPPYVGGHYSNGPVAVEYLANSILP
GGANSGNFFNFSVAGATSGIGNYGDRGSATSSGIFGLPGISLEIEGYLLASGGVADPDALYFVWGGANDFLTLDSPTAAA
QNIAANVDKLMAAGATHFFVPNLPDLGLTPLAAEGNVQGLATLFSTTFNTALSSELAALGTQFPVAEILQFDTYSFFNRI
VGDPAVYGFTNAQASCLAFQAGGVQCSNPDQYIYWDDLHPTTQAHALFGSVFARAIPVPGTLFLLMLGWLILVFARGNWI
CKNLARPVNSMELVG

Sequences:

>Translated_335_residues
MGVLFLAFMLSGAVWATPFTSLYAFGDSLSDGGNSPTAVTSIYKLLGNNCDPTHPCPPYVGGHYSNGPVAVEYLANSILP
GGANSGNFFNFSVAGATSGIGNYGDRGSATSSGIFGLPGISLEIEGYLLASGGVADPDALYFVWGGANDFLTLDSPTAAA
QNIAANVDKLMAAGATHFFVPNLPDLGLTPLAAEGNVQGLATLFSTTFNTALSSELAALGTQFPVAEILQFDTYSFFNRI
VGDPAVYGFTNAQASCLAFQAGGVQCSNPDQYIYWDDLHPTTQAHALFGSVFARAIPVPGTLFLLMLGWLILVFARGNWI
CKNLARPVNSMELVG
>Mature_334_residues
GVLFLAFMLSGAVWATPFTSLYAFGDSLSDGGNSPTAVTSIYKLLGNNCDPTHPCPPYVGGHYSNGPVAVEYLANSILPG
GANSGNFFNFSVAGATSGIGNYGDRGSATSSGIFGLPGISLEIEGYLLASGGVADPDALYFVWGGANDFLTLDSPTAAAQ
NIAANVDKLMAAGATHFFVPNLPDLGLTPLAAEGNVQGLATLFSTTFNTALSSELAALGTQFPVAEILQFDTYSFFNRIV
GDPAVYGFTNAQASCLAFQAGGVQCSNPDQYIYWDDLHPTTQAHALFGSVFARAIPVPGTLFLLMLGWLILVFARGNWIC
KNLARPVNSMELVG

Specific function: Unknown

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005546
- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR017186
- InterPro:   IPR001087
- InterPro:   IPR008265
- InterPro:   IPR006315 [H]

Pfam domain/function: PF03797 Autotransporter; PF00657 Lipase_GDSL [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 34974; Mature: 34843

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVLFLAFMLSGAVWATPFTSLYAFGDSLSDGGNSPTAVTSIYKLLGNNCDPTHPCPPYV
CHHHHHHHHHCCCCHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
GGHYSNGPVAVEYLANSILPGGANSGNFFNFSVAGATSGIGNYGDRGSATSSGIFGLPGI
CCCCCCCCEEHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCC
SLEIEGYLLASGGVADPDALYFVWGGANDFLTLDSPTAAAQNIAANVDKLMAAGATHFFV
EEEEEEEEEECCCCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEC
PNLPDLGLTPLAAEGNVQGLATLFSTTFNTALSSELAALGTQFPVAEILQFDTYSFFNRI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VGDPAVYGFTNAQASCLAFQAGGVQCSNPDQYIYWDDLHPTTQAHALFGSVFARAIPVPG
HCCCCEEEECCCCCEEEEEECCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCH
TLFLLMLGWLILVFARGNWICKNLARPVNSMELVG
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHCCCC
>Mature Secondary Structure 
GVLFLAFMLSGAVWATPFTSLYAFGDSLSDGGNSPTAVTSIYKLLGNNCDPTHPCPPYV
HHHHHHHHHCCCCHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
GGHYSNGPVAVEYLANSILPGGANSGNFFNFSVAGATSGIGNYGDRGSATSSGIFGLPGI
CCCCCCCCEEHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCC
SLEIEGYLLASGGVADPDALYFVWGGANDFLTLDSPTAAAQNIAANVDKLMAAGATHFFV
EEEEEEEEEECCCCCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEC
PNLPDLGLTPLAAEGNVQGLATLFSTTFNTALSSELAALGTQFPVAEILQFDTYSFFNRI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VGDPAVYGFTNAQASCLAFQAGGVQCSNPDQYIYWDDLHPTTQAHALFGSVFARAIPVPG
HCCCCEEEECCCCCEEEEEECCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCH
TLFLLMLGWLILVFARGNWICKNLARPVNSMELVG
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10559163; 10984043 [H]