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The map label for this gene is norD [H]

Identifier: 114330537

GI number: 114330537

Start: 537942

End: 540005

Strand: Reverse

Name: norD [H]

Synonym: Neut_0518

Alternate gene names: 114330537

Gene position: 540005-537942 (Counterclockwise)

Preceding gene: 114330538

Following gene: 114330524

Centisome position: 20.29

GC content: 50.87

Gene sequence:

>2064_bases
ATGTGGCAATGGCTGGAGCTGGAAGAACAAATCGGCCGTCTCTGGCACCGACTAGTTGGCCAGTCTGAAAGTAGTTACCC
ACACTATCCTTCGGCCGCCGTTTCGCTGGAATCCATTCATGCAGCGTTGCGCACATTTTTTCATGGTATGGGCGGTGATC
ACGGTCTGTTACTGACGGCCACAACGCTACAAACGGTACGAAATCGTCCAAGTTGGAAACAGCGCCTGGGTCATCACCAA
GAAAAACTGCCGTTGGCGGTACTTGGCCCGGAACGATTATTACTGCCCGCCGAGATTTGCTTGTTCCCAGAAGCATCGCT
CAATCGGCAACTCTACTTCTGGTTAGCCGCTTTTTTTGCTATGACAGGCAAGAAAACGCTGATTAGATCAACCAATGTCA
TTGCGACTGCGCACGCTACCGAGAATGAAATGCAGCAGGCGGCAGCAAGTAGCAGTAAGCAATCCGGACATTTCGACGAA
ATAAGCCAGCATTGTCATCAATCCGCTTTTTCAAAGGATGATCCATTCCAGACTGATCTTTATTTTCTTCATTGTGCCTG
GCAAACCAGTCTTGCTATTTGTCAACGCTATCTGGGCTTAAGAAAAACATATCAGACACTGTGCTCTCATTTACTTCAAA
CACGTCCACCCCGTTCACTACCGACACAAGAGCACATTGTAGAATCCATTGTACTTGCCCTGCTTGGACAACCGTGTACT
GATCCGGCAGCAATCAATTTACTCGCACGCATCCAACAACCCGAACCGGATTTCAGTGATCTGCGTGCAGATAAAGGTTA
CCACCCGTTTCTGCCAGTGCCATTATGGGGCACGATAGAAATAGATTCACCGTCGGGTACTACCCGAATATTGTCCGCTG
ATGAAGATCGGGTTGATCATTCTGTCAATCAGGAAGATCGATGCAGTAGAAAAGCCCGGCGGAGAAAATTTGACCAGAGC
GAACGTAATGATCCCCTATTACTAAACCGTTTTGAAAAATTGATCACCTGGTCGGAAATGGTGAATGTCAACCGACCAGT
AGAAGATGATAATGAAGCAGGCGCTCGAGAAGTAGCTGATTCAATGGAAGAGCTGGCCGTTACTACCCATCGACGGCGCG
CCTCCACAGTATTGAAATTTGATCTTGATCTGGCACCAGAAGATACCGATCCAGCCAGCCTGCTTGCGAAACTAACTTAC
CCTGAATGGGATTATCGCCGCAAACAATATCACGCTGCCCATTGTCAGGTGCTGTGCCGAATCGCCAGTGAAACCGGAGA
GCAATGGGAACCCAGTGACGGTGCCCGGCGGCAGTTTCGCCGGATTTGCCGTCAGTTCGAGGCATTACGCCCTCGTAGGG
AAATTTTACGCGGCCAGCCGGATGGCGCAGAACTGGATTTGGATGCACTCGTACGCGCCCAAGCGGATCAGGCCGCTCAT
GGCATGGGTACAGATCGGCTCTATCTTGCTGCACGCGAACAAGCACGAGATCTGGCGGTCGCGGTGCTGGTAGATGTTTC
TCTCTCCACAGACAGCTGGATTGGCGGGCGGCGGGTGCTGGATATCGAGAAAGAAGCACTGGTTGCACTGGCCACTGGCA
TTGCCGCTTGTCAGGATTGTTTTTCAATTCACACCTTTACCTCACGCCAGCGCCATTTTGTGCAAATGACGACTGTGAAA
GATTTTAACGAACCTTTCAGCAGCCGGACATTGCGATGTATTGCAGCATTACGGCCAGGATACTACACCCGGATGGGCAC
AGCATTGCGCCATGTCAGCCAGTTACTGGCGCAACGACCAGAACGTCACCGCCTGATTCTGTTGCTGACTGATGGCAAAC
CCAACGATCTGGATCATTATGAAGGTCGCTACGGCGTTGAAGATACTCGCCAAGCGGTTATCGAAGCCCGGCGGCAAGGA
TTGCAATTGTTTGGCATCACCATCGACCATGAAGCACAAGCTTATTTTCCTTATCTGTTCGGCCGTGGTGGCTACGCCAT
CATCAATCGGCCGGAACGACTCATCAAAATTATTCCGGCACTCTATCGGCAACTGACTGGCTGA

Upstream 100 bases:

>100_bases
TGCAGGCAGCACAAGCCGCATTGATCGAACCATTAAGCGATGAGCCGGAAGTGCAACAAGGTTTATTTGAACTGATCCAC
GCTACTTTCGGTTAAGCACC

Downstream 100 bases:

>100_bases
CGTTCTTCAGAAGTTCCTTGGCTGCTGTCTATTTTATGAACCGCCTGATGGTATCCAGCAGCAGCTCGTTTTCAGGATGA
TCTTCCAGTGCTGTTTGCCA

Product: von Willebrand factor, type A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MWQWLELEEQIGRLWHRLVGQSESSYPHYPSAAVSLESIHAALRTFFHGMGGDHGLLLTATTLQTVRNRPSWKQRLGHHQ
EKLPLAVLGPERLLLPAEICLFPEASLNRQLYFWLAAFFAMTGKKTLIRSTNVIATAHATENEMQQAAASSSKQSGHFDE
ISQHCHQSAFSKDDPFQTDLYFLHCAWQTSLAICQRYLGLRKTYQTLCSHLLQTRPPRSLPTQEHIVESIVLALLGQPCT
DPAAINLLARIQQPEPDFSDLRADKGYHPFLPVPLWGTIEIDSPSGTTRILSADEDRVDHSVNQEDRCSRKARRRKFDQS
ERNDPLLLNRFEKLITWSEMVNVNRPVEDDNEAGAREVADSMEELAVTTHRRRASTVLKFDLDLAPEDTDPASLLAKLTY
PEWDYRRKQYHAAHCQVLCRIASETGEQWEPSDGARRQFRRICRQFEALRPRREILRGQPDGAELDLDALVRAQADQAAH
GMGTDRLYLAAREQARDLAVAVLVDVSLSTDSWIGGRRVLDIEKEALVALATGIAACQDCFSIHTFTSRQRHFVQMTTVK
DFNEPFSSRTLRCIAALRPGYYTRMGTALRHVSQLLAQRPERHRLILLLTDGKPNDLDHYEGRYGVEDTRQAVIEARRQG
LQLFGITIDHEAQAYFPYLFGRGGYAIINRPERLIKIIPALYRQLTG

Sequences:

>Translated_687_residues
MWQWLELEEQIGRLWHRLVGQSESSYPHYPSAAVSLESIHAALRTFFHGMGGDHGLLLTATTLQTVRNRPSWKQRLGHHQ
EKLPLAVLGPERLLLPAEICLFPEASLNRQLYFWLAAFFAMTGKKTLIRSTNVIATAHATENEMQQAAASSSKQSGHFDE
ISQHCHQSAFSKDDPFQTDLYFLHCAWQTSLAICQRYLGLRKTYQTLCSHLLQTRPPRSLPTQEHIVESIVLALLGQPCT
DPAAINLLARIQQPEPDFSDLRADKGYHPFLPVPLWGTIEIDSPSGTTRILSADEDRVDHSVNQEDRCSRKARRRKFDQS
ERNDPLLLNRFEKLITWSEMVNVNRPVEDDNEAGAREVADSMEELAVTTHRRRASTVLKFDLDLAPEDTDPASLLAKLTY
PEWDYRRKQYHAAHCQVLCRIASETGEQWEPSDGARRQFRRICRQFEALRPRREILRGQPDGAELDLDALVRAQADQAAH
GMGTDRLYLAAREQARDLAVAVLVDVSLSTDSWIGGRRVLDIEKEALVALATGIAACQDCFSIHTFTSRQRHFVQMTTVK
DFNEPFSSRTLRCIAALRPGYYTRMGTALRHVSQLLAQRPERHRLILLLTDGKPNDLDHYEGRYGVEDTRQAVIEARRQG
LQLFGITIDHEAQAYFPYLFGRGGYAIINRPERLIKIIPALYRQLTG
>Mature_687_residues
MWQWLELEEQIGRLWHRLVGQSESSYPHYPSAAVSLESIHAALRTFFHGMGGDHGLLLTATTLQTVRNRPSWKQRLGHHQ
EKLPLAVLGPERLLLPAEICLFPEASLNRQLYFWLAAFFAMTGKKTLIRSTNVIATAHATENEMQQAAASSSKQSGHFDE
ISQHCHQSAFSKDDPFQTDLYFLHCAWQTSLAICQRYLGLRKTYQTLCSHLLQTRPPRSLPTQEHIVESIVLALLGQPCT
DPAAINLLARIQQPEPDFSDLRADKGYHPFLPVPLWGTIEIDSPSGTTRILSADEDRVDHSVNQEDRCSRKARRRKFDQS
ERNDPLLLNRFEKLITWSEMVNVNRPVEDDNEAGAREVADSMEELAVTTHRRRASTVLKFDLDLAPEDTDPASLLAKLTY
PEWDYRRKQYHAAHCQVLCRIASETGEQWEPSDGARRQFRRICRQFEALRPRREILRGQPDGAELDLDALVRAQADQAAH
GMGTDRLYLAAREQARDLAVAVLVDVSLSTDSWIGGRRVLDIEKEALVALATGIAACQDCFSIHTFTSRQRHFVQMTTVK
DFNEPFSSRTLRCIAALRPGYYTRMGTALRHVSQLLAQRPERHRLILLLTDGKPNDLDHYEGRYGVEDTRQAVIEARRQG
LQLFGITIDHEAQAYFPYLFGRGGYAIINRPERLIKIIPALYRQLTG

Specific function: Part of the operon norEFCBQD encoding nitric oxide reductase. Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection [H]

COG id: COG4548

COG function: function code P; Nitric oxide reductase activation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 78197; Mature: 78197

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQWLELEEQIGRLWHRLVGQSESSYPHYPSAAVSLESIHAALRTFFHGMGGDHGLLLTA
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEH
TTLQTVRNRPSWKQRLGHHQEKLPLAVLGPERLLLPAEICLFPEASLNRQLYFWLAAFFA
HHHHHHHCCCCHHHHHCCHHHHCCEEEECCCHHCCCHHHHCCCCCCCCHHHHHHHHHHHH
MTGKKTLIRSTNVIATAHATENEMQQAAASSSKQSGHFDEISQHCHQSAFSKDDPFQTDL
HCCCHHHEECCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
YFLHCAWQTSLAICQRYLGLRKTYQTLCSHLLQTRPPRSLPTQEHIVESIVLALLGQPCT
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCC
DPAAINLLARIQQPEPDFSDLRADKGYHPFLPVPLWGTIEIDSPSGTTRILSADEDRVDH
CHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCHHHHHC
SVNQEDRCSRKARRRKFDQSERNDPLLLNRFEKLITWSEMVNVNRPVEDDNEAGAREVAD
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SMEELAVTTHRRRASTVLKFDLDLAPEDTDPASLLAKLTYPEWDYRRKQYHAAHCQVLCR
HHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IASETGEQWEPSDGARRQFRRICRQFEALRPRREILRGQPDGAELDLDALVRAQADQAAH
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GMGTDRLYLAAREQARDLAVAVLVDVSLSTDSWIGGRRVLDIEKEALVALATGIAACQDC
CCCCCCEEEHHHHHHHHHEEEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
FSIHTFTSRQRHFVQMTTVKDFNEPFSSRTLRCIAALRPGYYTRMGTALRHVSQLLAQRP
HHHHHHHHCCHHEEEEEHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
ERHRLILLLTDGKPNDLDHYEGRYGVEDTRQAVIEARRQGLQLFGITIDHEAQAYFPYLF
CCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHCCHHC
GRGGYAIINRPERLIKIIPALYRQLTG
CCCCEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWQWLELEEQIGRLWHRLVGQSESSYPHYPSAAVSLESIHAALRTFFHGMGGDHGLLLTA
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEH
TTLQTVRNRPSWKQRLGHHQEKLPLAVLGPERLLLPAEICLFPEASLNRQLYFWLAAFFA
HHHHHHHCCCCHHHHHCCHHHHCCEEEECCCHHCCCHHHHCCCCCCCCHHHHHHHHHHHH
MTGKKTLIRSTNVIATAHATENEMQQAAASSSKQSGHFDEISQHCHQSAFSKDDPFQTDL
HCCCHHHEECCCEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
YFLHCAWQTSLAICQRYLGLRKTYQTLCSHLLQTRPPRSLPTQEHIVESIVLALLGQPCT
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCC
DPAAINLLARIQQPEPDFSDLRADKGYHPFLPVPLWGTIEIDSPSGTTRILSADEDRVDH
CHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCHHHHHC
SVNQEDRCSRKARRRKFDQSERNDPLLLNRFEKLITWSEMVNVNRPVEDDNEAGAREVAD
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
SMEELAVTTHRRRASTVLKFDLDLAPEDTDPASLLAKLTYPEWDYRRKQYHAAHCQVLCR
HHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
IASETGEQWEPSDGARRQFRRICRQFEALRPRREILRGQPDGAELDLDALVRAQADQAAH
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHC
GMGTDRLYLAAREQARDLAVAVLVDVSLSTDSWIGGRRVLDIEKEALVALATGIAACQDC
CCCCCCEEEHHHHHHHHHEEEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
FSIHTFTSRQRHFVQMTTVKDFNEPFSSRTLRCIAALRPGYYTRMGTALRHVSQLLAQRP
HHHHHHHHCCHHEEEEEHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
ERHRLILLLTDGKPNDLDHYEGRYGVEDTRQAVIEARRQGLQLFGITIDHEAQAYFPYLF
CCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHHCCHHC
GRGGYAIINRPERLIKIIPALYRQLTG
CCCCEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA