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The map label for this gene is mtgA

Identifier: 114330514

GI number: 114330514

Start: 508525

End: 509259

Strand: Reverse

Name: mtgA

Synonym: Neut_0495

Alternate gene names: 114330514

Gene position: 509259-508525 (Counterclockwise)

Preceding gene: 114330515

Following gene: 114330513

Centisome position: 19.14

GC content: 48.03

Gene sequence:

>735_bases
GTGAAACTGACCAAAACATCCCGACCAACCACACCCCAACCAGGATTGATCAGCACCTGGCTGTTACGCCCATTACTGCT
GCTCCTGGCAATTGCATTACTGTATCAATCCTGGTTTCTGCTACACATCATCTACTGGCGTACTTACCACCCAACCACCA
GCGCATTCATGCAAGATCGCCTGGAAACCATGCACCGACAGAATCCGGCTGCAAAATTACAGCATCGCTGGGTAGATTAC
GAACAGATTTCCAATCATCTTAAACGGGCAGTCATCGCCACTGAAGATGCCCGTTTTATGCAACACCAGGGATTTGACTA
CAAGGCAATTGAAGTAGCCTGGAAAAAAAACCTGAAACAACGCAAACTGGCTGCTGGCGGCTCAACCATCAGCCAGCAGC
TTGCTAAAAATTTGTTTTTATCGAGCGAAAAAACCGTATGGCGTAAATTACAGGAAACCCTCATCACACTGATACTGGAA
GAATTTCTGAGCAAACGGCGTATTCTGGAAATTTACCTGAATGTCATTGAATGGGGAGAAGGTGTATTCGGCATTGAAGC
CGCAGCGCGCCACTATTTTGGAATACCTGCGTCATCTCTCGCACCTGAACAATCCGCCTGGCTGGCGTCAATCATCTCCA
ACCCGCGTTTTTATGATACGCATCGCCAATCACCCAGATTGCTCAAAAAAGCCCGGATCATTCTGTCACGCCTGCCGACA
GCAAAAATCCCGTAA

Upstream 100 bases:

>100_bases
TCGAACAAGCCGCCGAATCCTTTCTGCTTTGGCACGGTATCCGTCCTGAAACACAGAACGTCATCCGACAACTCAGAGAT
GAATTGCACCTCCATGCCTC

Downstream 100 bases:

>100_bases
AAAACAGAAACAAACATGAACAAGGCTGAACGAATAACCTCGTCTGATATGAAACATACATACCGATACCTGCTATGGTT
GCTGCTTCCATGCTTGCTCC

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKLTKTSRPTTPQPGLISTWLLRPLLLLLAIALLYQSWFLLHIIYWRTYHPTTSAFMQDRLETMHRQNPAAKLQHRWVDY
EQISNHLKRAVIATEDARFMQHQGFDYKAIEVAWKKNLKQRKLAAGGSTISQQLAKNLFLSSEKTVWRKLQETLITLILE
EFLSKRRILEIYLNVIEWGEGVFGIEAAARHYFGIPASSLAPEQSAWLASIISNPRFYDTHRQSPRLLKKARIILSRLPT
AKIP

Sequences:

>Translated_244_residues
MKLTKTSRPTTPQPGLISTWLLRPLLLLLAIALLYQSWFLLHIIYWRTYHPTTSAFMQDRLETMHRQNPAAKLQHRWVDY
EQISNHLKRAVIATEDARFMQHQGFDYKAIEVAWKKNLKQRKLAAGGSTISQQLAKNLFLSSEKTVWRKLQETLITLILE
EFLSKRRILEIYLNVIEWGEGVFGIEAAARHYFGIPASSLAPEQSAWLASIISNPRFYDTHRQSPRLLKKARIILSRLPT
AKIP
>Mature_244_residues
MKLTKTSRPTTPQPGLISTWLLRPLLLLLAIALLYQSWFLLHIIYWRTYHPTTSAFMQDRLETMHRQNPAAKLQHRWVDY
EQISNHLKRAVIATEDARFMQHQGFDYKAIEVAWKKNLKQRKLAAGGSTISQQLAKNLFLSSEKTVWRKLQETLITLILE
EFLSKRRILEIYLNVIEWGEGVFGIEAAARHYFGIPASSLAPEQSAWLASIISNPRFYDTHRQSPRLLKKARIILSRLPT
AKIP

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=139, Percent_Identity=48.9208633093525, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082258, Length=161, Percent_Identity=37.2670807453416, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1786343, Length=158, Percent_Identity=36.0759493670886, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1788867, Length=161, Percent_Identity=31.055900621118, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_NITEC (Q0AIQ0)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746736.1
- ProteinModelPortal:   Q0AIQ0
- SMR:   Q0AIQ0
- STRING:   Q0AIQ0
- GeneID:   4272474
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0495
- NMPDR:   fig|335283.3.peg.1372
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   RISIHLK
- PhylomeDB:   Q0AIQ0
- ProtClustDB:   PRK00056
- BioCyc:   NEUT335283:NEUT_0495-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 28344; Mature: 28344

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1317a2c4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTKTSRPTTPQPGLISTWLLRPLLLLLAIALLYQSWFLLHIIYWRTYHPTTSAFMQDR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LETMHRQNPAAKLQHRWVDYEQISNHLKRAVIATEDARFMQHQGFDYKAIEVAWKKNLKQ
HHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RKLAAGGSTISQQLAKNLFLSSEKTVWRKLQETLITLILEEFLSKRRILEIYLNVIEWGE
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVFGIEAAARHYFGIPASSLAPEQSAWLASIISNPRFYDTHRQSPRLLKKARIILSRLPT
CCHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
AKIP
CCCH
>Mature Secondary Structure
MKLTKTSRPTTPQPGLISTWLLRPLLLLLAIALLYQSWFLLHIIYWRTYHPTTSAFMQDR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LETMHRQNPAAKLQHRWVDYEQISNHLKRAVIATEDARFMQHQGFDYKAIEVAWKKNLKQ
HHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RKLAAGGSTISQQLAKNLFLSSEKTVWRKLQETLITLILEEFLSKRRILEIYLNVIEWGE
HHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GVFGIEAAARHYFGIPASSLAPEQSAWLASIISNPRFYDTHRQSPRLLKKARIILSRLPT
CCHHHHHHHHHHCCCCCHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
AKIP
CCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA