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The map label for this gene is arnT1 [H]

Identifier: 114330484

GI number: 114330484

Start: 478075

End: 480690

Strand: Reverse

Name: arnT1 [H]

Synonym: Neut_0464

Alternate gene names: 114330484

Gene position: 480690-478075 (Counterclockwise)

Preceding gene: 114330485

Following gene: 114330477

Centisome position: 18.06

GC content: 47.78

Gene sequence:

>2616_bases
ATGCAATTTTCACTCATTATTCCTACCCTGAACGAAGCTGGAAATATCGACCTCCTACTAACGAGTATTTTCTCTCATGA
TAACTTGGGAGATCAGTTTGAAGTCATTATCGTGGATGACAGTTCCACGGATGGCACTCCTGACAAAGTCAGAAAATGGC
AAAACACTCATAACGTACATTTGATTGAAAGGCATGCACGGCCCGATCTAACTGCTTCTATTCTCGACGGAACAGCAGCC
GCCAAGTATGAAGTCATTGCAGTCATGGATGCTGATTTGAGCCATCCGCCAGAACGATTGGCCTCACTGATCCAGCCGAT
TCTGGATGGCACTCACGACATAACGATCGGCAGTCGTTACATAGCTGGTGGCGATACTATCGGCTGGCCTTTCTATCGTC
TCTGGCTGTCCCGGGCAGGGGGCTGGCTTGCACGCACTATTTGTGATGTAAATGACGCAACTTCGGGCTTCTTTGCTTTC
CGAAAGGAGCTGATCAAAAATATTACAGAAAATGCTCGCGGCTATAAAATCCTACTGGAACTGCTGATGACAGGGCGTGA
ACAGCTGCGTGTAAAAGAAATCCCGATCCACTTTCACAATCGACTGCACGGAAGCTCCAAGCTCTCCCTTTCACATCATC
TTACTTATCTGCAGCAACTCATTACACTGGCTGGTGGCACCGTCTCTTTCTACACAGCAAGCCGCTTTGCCATGGTTGGA
TTTTTAGGTGTCTTTGTCGATGTATTAATTTTTCAATGGATGACCGGGCAGGGTATCAGTCTGGCAACCGCACATATTTC
CAGTTTCATCGCAGCAGCCAGCTTCAACTATGCTTTGAATACCAAATGGTCATTCCGGCTGCAGCATTCAGGACATTTAC
ATTGGAGCCAGTTCTCTCGCTTTCTGATCGTTGGAATATTTGCAATGCTCCTGAGAGGAGCCGTTCTGGCCTGGCTGGTC
TATACCTGGAACATATCAACTGAATGGGCTATTTTCCCTGCGATTATCGCGACAGCTATTGTAAATTACCTTGGATCTGC
TTTTTACGTATTCCCACGAACCAAGCCCGCTGTTTCTACCGATACGCGATGGCGCATTGCTGCCGTAGGTATTGTCTGTT
TCGTCATCCTGTTGCGCCTGGTTTACATGAGTGTGGCGCAGCTAATCCCCGATGAAGCTTATTACTGGCAATACGCACAA
CATATGGATTTGAGCTTTTTTGATCATCCGCCGATGGTGGCCTGGTTGATCTGGCTGGGAACCGCGCTGGCTGGCCAGAA
TGAATTTGGAGTAAGAATCGGCGCCTTCTTGTGCGGATTGATCGCAATGGCTTATTTATACGCCCTTGCACGCAACCTCT
ACGATAAATCTACCGCTATGCGCTCAGTATTGCTGCTTGCCATCGTACCTTTTGGCTTTGCAGCAGGACTGGCAATGACA
CCAGATGCACCACTGGTTGCTGCTTGGGCAGCCACACTTTACTACATGGAGCGAGCCTTGCTCGCAAATCAGAATCGAGC
ATGGCTCGGGGTAGGTATTGCTTTCGGTCTTGGGATTCTGTCCAAATACACACTTGGACTGCTTGGCATCGCTGCACTGG
TTTTCGCTATCCTGGATCCAGTTGCGCGCCGCTGGCTCTTGCGCCCACATCCCTATGTAGCTGTATTAATTGCGCTGATA
TTGTTCAGCCCCGTGATCATCTGGAATATGGAAAATGACTGGGCTTCCTTCCTGTTTCAGACCAATAGAGTTGGCAAAAC
ACACCACGAATTTGCAACGCCTAAGTTAATACTTCAAATTGCAATTATGCTTACGCCAGTTGGACTGGCCGCAGCGGTAC
TTGCATTGCGTTCAGTTTTTCTGAGCTACCCCCAGACAACCCGTAAATCTCTTTTCATTGGCGTATTCACTGGGGTTCCA
CTAATGGTCTTTCTGATAGCCAGTACCTTCGGTTCTTTGCGCTTCCACTGGACTGGTCCACTCTGGTTAGCGTTGATACC
CACCATGGCCTGGATGATCGGACAAAAGAATATATTCAAGAATATCTCGGGATGGCTGAGCGCTGCCTGGCAGCCAATGA
TCACCGTGTCATTACTGACCTACGCCTTCATTTTGCATTATGTCACGCTGGGAATACCTGGACTCCCTTATCAATTTCTG
AGCGAGCATTATTTCTGGAGGGAAACCACAGCAGAAGTCGAAAAAATTGCTGATGAAATCAGGCAAACAACAGGAGAAGC
ACCAATTGTGGTCGGCATGAGCAAATGGTCAATAGCCAGTGCGCTTGCGTTTTACAATAATAATCACCCTGCCCTTGATA
TCCGATCCCGCAATCTGTTTGGCGAACACGCGGCCATGTACAGTTTTTGGTACCCGTCCGAATCCCCTACTAACCGGTCC
ATTCTGCTGATTGGAATGAAACGGCAGGCATTAGAATCAGGCTCGGCCGAAGGAAATTTTGAAAGAATACTGATAAAACC
TGGAAGTACGAATACTCGTGAAATCTATCGACATGATGGCGTTTTATTGCGTACTCTCTATTATCGTACTGCAGAAGGAT
ATCGCGGCAATAATCTCACTCCATCATCAACATCTGCTTCTGTAGAAAACAGGTAG

Upstream 100 bases:

>100_bases
GATCCTGAATCAAGATGATCTTTCTCTAATACGTTGTCACCCCCCGGGAAGCCAACTCTAAACCCATGTCAACAGGCCCC
GGGAATAACTTGAGCTTAAC

Downstream 100 bases:

>100_bases
CCGCGCTTAGTGATTATGGCCAAAAAATAGCCCTATCAACCATATCGTACTGATCCCCAGAACGATAAGCGTGACCTGTT
GAACAGTTGCACCGATCTCG

Product: dolichyl-phosphate beta-D-mannosyltransferase

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase 1; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase 1 [H]

Number of amino acids: Translated: 871; Mature: 871

Protein sequence:

>871_residues
MQFSLIIPTLNEAGNIDLLLTSIFSHDNLGDQFEVIIVDDSSTDGTPDKVRKWQNTHNVHLIERHARPDLTASILDGTAA
AKYEVIAVMDADLSHPPERLASLIQPILDGTHDITIGSRYIAGGDTIGWPFYRLWLSRAGGWLARTICDVNDATSGFFAF
RKELIKNITENARGYKILLELLMTGREQLRVKEIPIHFHNRLHGSSKLSLSHHLTYLQQLITLAGGTVSFYTASRFAMVG
FLGVFVDVLIFQWMTGQGISLATAHISSFIAAASFNYALNTKWSFRLQHSGHLHWSQFSRFLIVGIFAMLLRGAVLAWLV
YTWNISTEWAIFPAIIATAIVNYLGSAFYVFPRTKPAVSTDTRWRIAAVGIVCFVILLRLVYMSVAQLIPDEAYYWQYAQ
HMDLSFFDHPPMVAWLIWLGTALAGQNEFGVRIGAFLCGLIAMAYLYALARNLYDKSTAMRSVLLLAIVPFGFAAGLAMT
PDAPLVAAWAATLYYMERALLANQNRAWLGVGIAFGLGILSKYTLGLLGIAALVFAILDPVARRWLLRPHPYVAVLIALI
LFSPVIIWNMENDWASFLFQTNRVGKTHHEFATPKLILQIAIMLTPVGLAAAVLALRSVFLSYPQTTRKSLFIGVFTGVP
LMVFLIASTFGSLRFHWTGPLWLALIPTMAWMIGQKNIFKNISGWLSAAWQPMITVSLLTYAFILHYVTLGIPGLPYQFL
SEHYFWRETTAEVEKIADEIRQTTGEAPIVVGMSKWSIASALAFYNNNHPALDIRSRNLFGEHAAMYSFWYPSESPTNRS
ILLIGMKRQALESGSAEGNFERILIKPGSTNTREIYRHDGVLLRTLYYRTAEGYRGNNLTPSSTSASVENR

Sequences:

>Translated_871_residues
MQFSLIIPTLNEAGNIDLLLTSIFSHDNLGDQFEVIIVDDSSTDGTPDKVRKWQNTHNVHLIERHARPDLTASILDGTAA
AKYEVIAVMDADLSHPPERLASLIQPILDGTHDITIGSRYIAGGDTIGWPFYRLWLSRAGGWLARTICDVNDATSGFFAF
RKELIKNITENARGYKILLELLMTGREQLRVKEIPIHFHNRLHGSSKLSLSHHLTYLQQLITLAGGTVSFYTASRFAMVG
FLGVFVDVLIFQWMTGQGISLATAHISSFIAAASFNYALNTKWSFRLQHSGHLHWSQFSRFLIVGIFAMLLRGAVLAWLV
YTWNISTEWAIFPAIIATAIVNYLGSAFYVFPRTKPAVSTDTRWRIAAVGIVCFVILLRLVYMSVAQLIPDEAYYWQYAQ
HMDLSFFDHPPMVAWLIWLGTALAGQNEFGVRIGAFLCGLIAMAYLYALARNLYDKSTAMRSVLLLAIVPFGFAAGLAMT
PDAPLVAAWAATLYYMERALLANQNRAWLGVGIAFGLGILSKYTLGLLGIAALVFAILDPVARRWLLRPHPYVAVLIALI
LFSPVIIWNMENDWASFLFQTNRVGKTHHEFATPKLILQIAIMLTPVGLAAAVLALRSVFLSYPQTTRKSLFIGVFTGVP
LMVFLIASTFGSLRFHWTGPLWLALIPTMAWMIGQKNIFKNISGWLSAAWQPMITVSLLTYAFILHYVTLGIPGLPYQFL
SEHYFWRETTAEVEKIADEIRQTTGEAPIVVGMSKWSIASALAFYNNNHPALDIRSRNLFGEHAAMYSFWYPSESPTNRS
ILLIGMKRQALESGSAEGNFERILIKPGSTNTREIYRHDGVLLRTLYYRTAEGYRGNNLTPSSTSASVENR
>Mature_871_residues
MQFSLIIPTLNEAGNIDLLLTSIFSHDNLGDQFEVIIVDDSSTDGTPDKVRKWQNTHNVHLIERHARPDLTASILDGTAA
AKYEVIAVMDADLSHPPERLASLIQPILDGTHDITIGSRYIAGGDTIGWPFYRLWLSRAGGWLARTICDVNDATSGFFAF
RKELIKNITENARGYKILLELLMTGREQLRVKEIPIHFHNRLHGSSKLSLSHHLTYLQQLITLAGGTVSFYTASRFAMVG
FLGVFVDVLIFQWMTGQGISLATAHISSFIAAASFNYALNTKWSFRLQHSGHLHWSQFSRFLIVGIFAMLLRGAVLAWLV
YTWNISTEWAIFPAIIATAIVNYLGSAFYVFPRTKPAVSTDTRWRIAAVGIVCFVILLRLVYMSVAQLIPDEAYYWQYAQ
HMDLSFFDHPPMVAWLIWLGTALAGQNEFGVRIGAFLCGLIAMAYLYALARNLYDKSTAMRSVLLLAIVPFGFAAGLAMT
PDAPLVAAWAATLYYMERALLANQNRAWLGVGIAFGLGILSKYTLGLLGIAALVFAILDPVARRWLLRPHPYVAVLIALI
LFSPVIIWNMENDWASFLFQTNRVGKTHHEFATPKLILQIAIMLTPVGLAAAVLALRSVFLSYPQTTRKSLFIGVFTGVP
LMVFLIASTFGSLRFHWTGPLWLALIPTMAWMIGQKNIFKNISGWLSAAWQPMITVSLLTYAFILHYVTLGIPGLPYQFL
SEHYFWRETTAEVEKIADEIRQTTGEAPIVVGMSKWSIASALAFYNNNHPALDIRSRNLFGEHAAMYSFWYPSESPTNRS
ILLIGMKRQALESGSAEGNFERILIKPGSTNTREIYRHDGVLLRTLYYRTAEGYRGNNLTPSSTSASVENR

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=237, Percent_Identity=32.0675105485232, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71999402, Length=230, Percent_Identity=30.8695652173913, Blast_Score=99, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325441, Length=234, Percent_Identity=35.042735042735, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24585265, Length=231, Percent_Identity=29.4372294372294, Blast_Score=115, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022839
- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: =2.4.2.43 [H]

Molecular weight: Translated: 97417; Mature: 97417

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSLIIPTLNEAGNIDLLLTSIFSHDNLGDQFEVIIVDDSSTDGTPDKVRKWQNTHNVH
CCEEEEEECCCCCCCHHEEHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCEE
LIERHARPDLTASILDGTAAAKYEVIAVMDADLSHPPERLASLIQPILDGTHDITIGSRY
EEEECCCCCCHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCEE
IAGGDTIGWPFYRLWLSRAGGWLARTICDVNDATSGFFAFRKELIKNITENARGYKILLE
EECCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LLMTGREQLRVKEIPIHFHNRLHGSSKLSLSHHLTYLQQLITLAGGTVSFYTASRFAMVG
HHHCCHHHCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
FLGVFVDVLIFQWMTGQGISLATAHISSFIAAASFNYALNTKWSFRLQHSGHLHWSQFSR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCHHHHHH
FLIVGIFAMLLRGAVLAWLVYTWNISTEWAIFPAIIATAIVNYLGSAFYVFPRTKPAVST
HHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
DTRWRIAAVGIVCFVILLRLVYMSVAQLIPDEAYYWQYAQHMDLSFFDHPPMVAWLIWLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
TALAGQNEFGVRIGAFLCGLIAMAYLYALARNLYDKSTAMRSVLLLAIVPFGFAAGLAMT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PDAPLVAAWAATLYYMERALLANQNRAWLGVGIAFGLGILSKYTLGLLGIAALVFAILDP
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VARRWLLRPHPYVAVLIALILFSPVIIWNMENDWASFLFQTNRVGKTHHEFATPKLILQI
HHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCHHHHCCHHHHHHH
AIMLTPVGLAAAVLALRSVFLSYPQTTRKSLFIGVFTGVPLMVFLIASTFGSLRFHWTGP
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHHEEEEHHHHHHHHHHHHHHHHCCEEEEECCH
LWLALIPTMAWMIGQKNIFKNISGWLSAAWQPMITVSLLTYAFILHYVTLGIPGLPYQFL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SEHYFWRETTAEVEKIADEIRQTTGEAPIVVGMSKWSIASALAFYNNNHPALDIRSRNLF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEECCCCC
GEHAAMYSFWYPSESPTNRSILLIGMKRQALESGSAEGNFERILIKPGSTNTREIYRHDG
CCHHHEEEEECCCCCCCCCEEEEEECHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHCCC
VLLRTLYYRTAEGYRGNNLTPSSTSASVENR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQFSLIIPTLNEAGNIDLLLTSIFSHDNLGDQFEVIIVDDSSTDGTPDKVRKWQNTHNVH
CCEEEEEECCCCCCCHHEEHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCEE
LIERHARPDLTASILDGTAAAKYEVIAVMDADLSHPPERLASLIQPILDGTHDITIGSRY
EEEECCCCCCHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCEE
IAGGDTIGWPFYRLWLSRAGGWLARTICDVNDATSGFFAFRKELIKNITENARGYKILLE
EECCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LLMTGREQLRVKEIPIHFHNRLHGSSKLSLSHHLTYLQQLITLAGGTVSFYTASRFAMVG
HHHCCHHHCEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
FLGVFVDVLIFQWMTGQGISLATAHISSFIAAASFNYALNTKWSFRLQHSGHLHWSQFSR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCHHHHHH
FLIVGIFAMLLRGAVLAWLVYTWNISTEWAIFPAIIATAIVNYLGSAFYVFPRTKPAVST
HHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
DTRWRIAAVGIVCFVILLRLVYMSVAQLIPDEAYYWQYAQHMDLSFFDHPPMVAWLIWLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
TALAGQNEFGVRIGAFLCGLIAMAYLYALARNLYDKSTAMRSVLLLAIVPFGFAAGLAMT
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PDAPLVAAWAATLYYMERALLANQNRAWLGVGIAFGLGILSKYTLGLLGIAALVFAILDP
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VARRWLLRPHPYVAVLIALILFSPVIIWNMENDWASFLFQTNRVGKTHHEFATPKLILQI
HHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCHHHHCCHHHHHHH
AIMLTPVGLAAAVLALRSVFLSYPQTTRKSLFIGVFTGVPLMVFLIASTFGSLRFHWTGP
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHHEEEEHHHHHHHHHHHHHHHHCCEEEEECCH
LWLALIPTMAWMIGQKNIFKNISGWLSAAWQPMITVSLLTYAFILHYVTLGIPGLPYQFL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
SEHYFWRETTAEVEKIADEIRQTTGEAPIVVGMSKWSIASALAFYNNNHPALDIRSRNLF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEECCCCC
GEHAAMYSFWYPSESPTNRSILLIGMKRQALESGSAEGNFERILIKPGSTNTREIYRHDG
CCHHHEEEEECCCCCCCCCEEEEEECHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHCCC
VLLRTLYYRTAEGYRGNNLTPSSTSASVENR
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA