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The map label for this gene is aroA

Identifier: 114330419

GI number: 114330419

Start: 404784

End: 406085

Strand: Direct

Name: aroA

Synonym: Neut_0398

Alternate gene names: 114330419

Gene position: 404784-406085 (Clockwise)

Preceding gene: 114330417

Following gene: 114330420

Centisome position: 15.21

GC content: 49.23

Gene sequence:

>1302_bases
ATGGAATGGCTTGATCTTCCTCTGGTTCGTTGTGCAGCAGGTAAGGTACGTTTGCCGGGTTCGAAAAGTATTTCTAACCG
TGTTCTTCTGTTGTCTGCACTTGCTGAAGGCACTACAACGATCAGTAATCTGCTCGAATCCGATGATACCGGGCGGATGT
TGGATGCTCTGAAGATGCTTGGGGTAGCTGTTACCCGCACTGATGAAGATCAGTATCTGATAACGGGGTGCAGTGGGAGA
TTTTCCGTAAAGGAAGCTGATCTGTTTTTGGGTAATGCCGGAACAGCCTTTCGTCCGTTAACTGCGGTATTGTCATTGAT
GCATGGTCATTATCATCTTTCAGGTGTGCCACGCATGCATGAGCGGCCGATTGGCGATTTAGTGGATGCGTTACGTCAAG
TTGGGGCTGTAATTACCTATCTTGAGCGAGAGCATTTTCCCCCATTGGAGATCCATCCGGCTGCAATCCACCCAGCTGAT
ATTCTTATCAATGGAAATATTTCCAGTCAGTTTCTCAGTGGATTGCTGATGGCGTTGCCTCTGGCTGGTGAACCAGCAAC
CATCATTGTCAACGGTACACTTATCTCACAACCCTACGTAACACTCACCATTGCGCAAATGGCCTATTTTGGCGTGCAGG
TTGAACGGGAATCCTGGCTGCGTTTTATCGTGCCAGGGAATCAGATTTATCACAGCCCGGGAAAGATCGTTGTTGAAGGG
GATGCGTCGTCTGCTTCCTATTTTCTTGCTGCCGGAGCTATAGCAGGTGGCCCGGTGCGTGTTGATGGCGTAGGACGCGA
TAGCTGTCAGGGAGATATCCGCTTTGTTGAAGCGCTGGAAGCGATGGGGGCTTGCATCAAAATGGGGAGTGACTGGATAG
AATCCAGTGCTCCAGGCTGCAGATCTGACGGCAAGGTTTTAAAGGCGATTGATTTTGATTGTAATCATATCCCTGATGCT
GCTATGACACTGGCTACAACCGCATTGTTTGCGCAAGGGACGACTACGCTCAGGAACATAGCGAGTTGGCGGGTCAAGGA
AACAGACCGGATCACTGCGATGTCAACAGAACTTCGCAAGCTGGGTGCTCAAGTGGAATCTGGTGATGATTTTCTGCGGA
TTACGCCGCCGGACGACCCTTTGGTGGCCAATACTGTGATTGATACCTACGATGATCACCGGATGGCGATGTGCTTTTCC
CTGATATCTTTGGGTACACCGGTGCGCATCAATGACCCACATTGTGTAGCTAAAACTTTCCCGGATTATTTTGAAAAATT
CACAGCCATTACACACCAATAA

Upstream 100 bases:

>100_bases
GATGATTCACGAAGCTGGATCAATTATTGTTGAACAAATGAAAAGAAATCATTATGTTTTGATTGATTCCTGCCTTTTAC
TGGCAGAAGGTCGCTAGCTT

Downstream 100 bases:

>100_bases
TTTCCAGAAGTGTATTGAACCCAAATTTCACAAGCAACAATTTAAATACCGGAAGTATCTTGCTTGGATCGAGTGAACCA
TGAAAAATCAATATGTTCCG

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MEWLDLPLVRCAAGKVRLPGSKSISNRVLLLSALAEGTTTISNLLESDDTGRMLDALKMLGVAVTRTDEDQYLITGCSGR
FSVKEADLFLGNAGTAFRPLTAVLSLMHGHYHLSGVPRMHERPIGDLVDALRQVGAVITYLEREHFPPLEIHPAAIHPAD
ILINGNISSQFLSGLLMALPLAGEPATIIVNGTLISQPYVTLTIAQMAYFGVQVERESWLRFIVPGNQIYHSPGKIVVEG
DASSASYFLAAGAIAGGPVRVDGVGRDSCQGDIRFVEALEAMGACIKMGSDWIESSAPGCRSDGKVLKAIDFDCNHIPDA
AMTLATTALFAQGTTTLRNIASWRVKETDRITAMSTELRKLGAQVESGDDFLRITPPDDPLVANTVIDTYDDHRMAMCFS
LISLGTPVRINDPHCVAKTFPDYFEKFTAITHQ

Sequences:

>Translated_433_residues
MEWLDLPLVRCAAGKVRLPGSKSISNRVLLLSALAEGTTTISNLLESDDTGRMLDALKMLGVAVTRTDEDQYLITGCSGR
FSVKEADLFLGNAGTAFRPLTAVLSLMHGHYHLSGVPRMHERPIGDLVDALRQVGAVITYLEREHFPPLEIHPAAIHPAD
ILINGNISSQFLSGLLMALPLAGEPATIIVNGTLISQPYVTLTIAQMAYFGVQVERESWLRFIVPGNQIYHSPGKIVVEG
DASSASYFLAAGAIAGGPVRVDGVGRDSCQGDIRFVEALEAMGACIKMGSDWIESSAPGCRSDGKVLKAIDFDCNHIPDA
AMTLATTALFAQGTTTLRNIASWRVKETDRITAMSTELRKLGAQVESGDDFLRITPPDDPLVANTVIDTYDDHRMAMCFS
LISLGTPVRINDPHCVAKTFPDYFEKFTAITHQ
>Mature_433_residues
MEWLDLPLVRCAAGKVRLPGSKSISNRVLLLSALAEGTTTISNLLESDDTGRMLDALKMLGVAVTRTDEDQYLITGCSGR
FSVKEADLFLGNAGTAFRPLTAVLSLMHGHYHLSGVPRMHERPIGDLVDALRQVGAVITYLEREHFPPLEIHPAAIHPAD
ILINGNISSQFLSGLLMALPLAGEPATIIVNGTLISQPYVTLTIAQMAYFGVQVERESWLRFIVPGNQIYHSPGKIVVEG
DASSASYFLAAGAIAGGPVRVDGVGRDSCQGDIRFVEALEAMGACIKMGSDWIESSAPGCRSDGKVLKAIDFDCNHIPDA
AMTLATTALFAQGTTTLRNIASWRVKETDRITAMSTELRKLGAQVESGDDFLRITPPDDPLVANTVIDTYDDHRMAMCFS
LISLGTPVRINDPHCVAKTFPDYFEKFTAITHQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=435, Percent_Identity=55.632183908046, Blast_Score=441, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6320332, Length=449, Percent_Identity=37.6391982182628, Blast_Score=231, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_NITEC (Q0AIZ5)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746641.1
- ProteinModelPortal:   Q0AIZ5
- SMR:   Q0AIZ5
- STRING:   Q0AIZ5
- GeneID:   4273460
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0398
- NMPDR:   fig|335283.3.peg.1993
- eggNOG:   COG0128
- HOGENOM:   HBG646626
- OMA:   GADIEWG
- PhylomeDB:   Q0AIZ5
- ProtClustDB:   PRK02427
- BioCyc:   NEUT335283:NEUT_0398-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 46841; Mature: 46841

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLDLPLVRCAAGKVRLPGSKSISNRVLLLSALAEGTTTISNLLESDDTGRMLDALKML
CCCCCCCHHHHCCCCEECCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCHHHHHHHHHH
GVAVTRTDEDQYLITGCSGRFSVKEADLFLGNAGTAFRPLTAVLSLMHGHYHLSGVPRMH
CEEEEECCCCCEEEEECCCCCEEEECEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCHH
ERPIGDLVDALRQVGAVITYLEREHFPPLEIHPAAIHPADILINGNISSQFLSGLLMALP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEECCEEEEEECCCHHHHHHHHHHHHC
LAGEPATIIVNGTLISQPYVTLTIAQMAYFGVQVERESWLRFIVPGNQIYHSPGKIVVEG
CCCCCCEEEEECEEECCCCCEEEHHHHHHHCEEEECCCCEEEEECCCEEEECCCEEEEEC
DASSASYFLAAGAIAGGPVRVDGVGRDSCQGDIRFVEALEAMGACIKMGSDWIESSAPGC
CCCCCEEEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
RSDGKVLKAIDFDCNHIPDAAMTLATTALFAQGTTTLRNIASWRVKETDRITAMSTELRK
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
LGAQVESGDDFLRITPPDDPLVANTVIDTYDDHRMAMCFSLISLGTPVRINDPHCVAKTF
HCCCCCCCCCEEEECCCCCCEEEHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHH
PDYFEKFTAITHQ
HHHHHHHHHHCCC
>Mature Secondary Structure
MEWLDLPLVRCAAGKVRLPGSKSISNRVLLLSALAEGTTTISNLLESDDTGRMLDALKML
CCCCCCCHHHHCCCCEECCCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCHHHHHHHHHH
GVAVTRTDEDQYLITGCSGRFSVKEADLFLGNAGTAFRPLTAVLSLMHGHYHLSGVPRMH
CEEEEECCCCCEEEEECCCCCEEEECEEEECCCCCHHHHHHHHHHHHHCCEEECCCCCHH
ERPIGDLVDALRQVGAVITYLEREHFPPLEIHPAAIHPADILINGNISSQFLSGLLMALP
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCEECCEEEEEECCCHHHHHHHHHHHHC
LAGEPATIIVNGTLISQPYVTLTIAQMAYFGVQVERESWLRFIVPGNQIYHSPGKIVVEG
CCCCCCEEEEECEEECCCCCEEEHHHHHHHCEEEECCCCEEEEECCCEEEECCCEEEEEC
DASSASYFLAAGAIAGGPVRVDGVGRDSCQGDIRFVEALEAMGACIKMGSDWIESSAPGC
CCCCCEEEEEECCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
RSDGKVLKAIDFDCNHIPDAAMTLATTALFAQGTTTLRNIASWRVKETDRITAMSTELRK
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
LGAQVESGDDFLRITPPDDPLVANTVIDTYDDHRMAMCFSLISLGTPVRINDPHCVAKTF
HCCCCCCCCCEEEECCCCCCEEEHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHH
PDYFEKFTAITHQ
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA