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The map label for this gene is aroK [H]

Identifier: 114330403

GI number: 114330403

Start: 383855

End: 384502

Strand: Reverse

Name: aroK [H]

Synonym: Neut_0382

Alternate gene names: 114330403

Gene position: 384502-383855 (Counterclockwise)

Preceding gene: 114330404

Following gene: 114330402

Centisome position: 14.45

GC content: 49.85

Gene sequence:

>648_bases
ATGGCTGTGGATTTACAGTACAATTGCATTATGCAACGCAGTAAAACCCCAACCACAAAAAATTCTGATGCCGAGTTGAT
ACCGGGCAACATCATTCTGATCGGGATGATGGGCGCTGGTAAAACAACGGTTGGAAAATTGCTGGCCAATCTTGTCGGCA
AAACTTTCATCGATGTCGATCATGAAATCCAGCAACGTACGGGAGTGGGGATCCCCGTGATCTTCGAAATAGAGGGAGAG
GCCGGGTTTCGCAAACGTGAAAGCGAAGTGCTGCGGGAAGTCGTCCAGCAGCAGAATATCGTCCTGGCGACAGGAGGTGG
TGCAATATTATATCCAGATAATCGCACTTTATTGCGGCAACACGGCACTGTGATTTATCTATGCGCACCTGTCTCCGAGT
TACGTCGCCGTACGCATCAGGATAAAAACCGTCCACTGCTGCAAACAGGAAATGCACATGCCAAGCTGGCCGGGCTGTTT
ACACAACGCGACCCGCTGTATCGTGAAACAGCACACATCATCATGGACAGCGGCAAACAAAGCGCCCGCACCTTCGTACA
GAAACTGCTGCAGAGATTGCATCAGCTCAATCAGGAATCAACCGGCGCTGAGCTGAAAAATCATCCCTCCGTTAAACAGC
CGAAATAA

Upstream 100 bases:

>100_bases
AAAGCATTTGTTGCCAGGTTTTTATAAACTGGCGGTTAATTCTATTTTTGCTGTATTTTTATTCCATTAAATCAGGATCC
ACCCTAGGGGAACTCGCAGG

Downstream 100 bases:

>100_bases
CAGCAGATTAATTTTATACCAGGCAAACCAACCTTTGAAGAGCGCCAGATGAATGCCATGGAATCAGTTGAAGTCGCACT
TGATACTCTCCCGGAAAATC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MAVDLQYNCIMQRSKTPTTKNSDAELIPGNIILIGMMGAGKTTVGKLLANLVGKTFIDVDHEIQQRTGVGIPVIFEIEGE
AGFRKRESEVLREVVQQQNIVLATGGGAILYPDNRTLLRQHGTVIYLCAPVSELRRRTHQDKNRPLLQTGNAHAKLAGLF
TQRDPLYRETAHIIMDSGKQSARTFVQKLLQRLHQLNQESTGAELKNHPSVKQPK

Sequences:

>Translated_215_residues
MAVDLQYNCIMQRSKTPTTKNSDAELIPGNIILIGMMGAGKTTVGKLLANLVGKTFIDVDHEIQQRTGVGIPVIFEIEGE
AGFRKRESEVLREVVQQQNIVLATGGGAILYPDNRTLLRQHGTVIYLCAPVSELRRRTHQDKNRPLLQTGNAHAKLAGLF
TQRDPLYRETAHIIMDSGKQSARTFVQKLLQRLHQLNQESTGAELKNHPSVKQPK
>Mature_214_residues
AVDLQYNCIMQRSKTPTTKNSDAELIPGNIILIGMMGAGKTTVGKLLANLVGKTFIDVDHEIQQRTGVGIPVIFEIEGEA
GFRKRESEVLREVVQQQNIVLATGGGAILYPDNRTLLRQHGTVIYLCAPVSELRRRTHQDKNRPLLQTGNAHAKLAGLFT
QRDPLYRETAHIIMDSGKQSARTFVQKLLQRLHQLNQESTGAELKNHPSVKQPK

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=40.3614457831325, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786587, Length=158, Percent_Identity=39.873417721519, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 23926; Mature: 23795

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDLQYNCIMQRSKTPTTKNSDAELIPGNIILIGMMGAGKTTVGKLLANLVGKTFIDVD
CEEECCHHHEEECCCCCCCCCCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
HEIQQRTGVGIPVIFEIEGEAGFRKRESEVLREVVQQQNIVLATGGGAILYPDNRTLLRQ
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCHHHHH
HGTVIYLCAPVSELRRRTHQDKNRPLLQTGNAHAKLAGLFTQRDPLYRETAHIIMDSGKQ
CCCEEEEECCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHH
SARTFVQKLLQRLHQLNQESTGAELKNHPSVKQPK
HHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
AVDLQYNCIMQRSKTPTTKNSDAELIPGNIILIGMMGAGKTTVGKLLANLVGKTFIDVD
EEECCHHHEEECCCCCCCCCCCCEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
HEIQQRTGVGIPVIFEIEGEAGFRKRESEVLREVVQQQNIVLATGGGAILYPDNRTLLRQ
HHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEECCCEEEECCCCHHHHH
HGTVIYLCAPVSELRRRTHQDKNRPLLQTGNAHAKLAGLFTQRDPLYRETAHIIMDSGKQ
CCCEEEEECCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCHH
SARTFVQKLLQRLHQLNQESTGAELKNHPSVKQPK
HHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]