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The map label for this gene is aroB

Identifier: 114330402

GI number: 114330402

Start: 382697

End: 383806

Strand: Reverse

Name: aroB

Synonym: Neut_0381

Alternate gene names: 114330402

Gene position: 383806-382697 (Counterclockwise)

Preceding gene: 114330403

Following gene: 114330401

Centisome position: 14.42

GC content: 52.52

Gene sequence:

>1110_bases
ATGAATGCCATGGAATCAGTTGAAGTCGCACTTGATACTCTCCCGGAAAATCGCAGTTACACCATTCATATCGGACAGGA
GCTGCTCACCAGGATTGACCTATTGCTCCCTCATCTGCCCGGCAAGAAAGCTGCAATTGTTACCAACACCACCATCGCGC
CGCTTTATCTGGAAAAACTGCGCAGCGCGCTGGCTGAACACCAGGTAGAAACCTTTGCGGTCATTCTGCCGGACGGTGAG
CAATATAAAAACTGGGAAACCCTGAATCTGATTTTCGATGCGCTGCTGGAACATCGCTGTGAACGCAAGACACCGCTGAT
CGCACTCGGAGGCGGGGTAGTCGGTGATCTGACCGGTTTTGCAGCTGCCAGCTATTTGCGTGGCGTACCCTTTATCCAGA
TTCCCACCACGCTGCTCGCCCAGGTGGATTCATCCGTAGGTGGAAAAACCGGCATTAATCATCCCCTGGGTAAAAACATG
ATCGGCGCTTTTTACCAGCCACGCCTGGTTTTAGCCGACTCCGCCACGCTCACTACCCTGCCGGACAGAGAATTACGTGC
CGGGATTGCAGAAGTCATCAAATATGGATTGATCCATGATGCAGATTTCTTCGATTGGCTGGAGCGTCACATGCAGCAGC
TGCTGGCGCGTGATCCTGAAACGATGAATTATGCCATACGCCGCAGCTGCGAAATCAAGGCAGAAATTGTTTCGCTGGAT
GAACGTGAAAGCGGTGTGCGTGCACTGCTCAATCTTGGGCATACATTTGGCCATGCTATCGAAAACACTATGGGCTATGG
CGCATGGCTGCATGGTGAAGCCGTTGCTGCCGGCACCCTCATGGCGGCCGATCTCTCCAAGCGCCTGCAACGCATCACTT
CACAGGATACCGATCGTATCCAGCACTTGTTTGAAAATGCCGGGCTGCCAGTAAAAGGCCCACGTATCACACCTGAACGC
TACCTGGAATCAATGCAACTCGATAAAAAAGTGAAGGACGGCGCAATCCGTTTCATCCTGCTGGATCGGATCGGCAAGGC
TTCACTGGACAACACTGTTCCCACTCTGCTGCTGCTTGAAACATTGTCAGCCTGTGTTGCCAATGCGTAA

Upstream 100 bases:

>100_bases
ATCAACCGGCGCTGAGCTGAAAAATCATCCCTCCGTTAAACAGCCGAAATAACAGCAGATTAATTTTATACCAGGCAAAC
CAACCTTTGAAGAGCGCCAG

Downstream 100 bases:

>100_bases
TAATCTGCCCCCCTACGCCGTATCCGATACCAACTCGCGCGGTCGCCGCATCCATGAAGATCCGCCGATCGGGCGCAGCC
AGTTTCAGCGCGATCGGGAT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MNAMESVEVALDTLPENRSYTIHIGQELLTRIDLLLPHLPGKKAAIVTNTTIAPLYLEKLRSALAEHQVETFAVILPDGE
QYKNWETLNLIFDALLEHRCERKTPLIALGGGVVGDLTGFAAASYLRGVPFIQIPTTLLAQVDSSVGGKTGINHPLGKNM
IGAFYQPRLVLADSATLTTLPDRELRAGIAEVIKYGLIHDADFFDWLERHMQQLLARDPETMNYAIRRSCEIKAEIVSLD
ERESGVRALLNLGHTFGHAIENTMGYGAWLHGEAVAAGTLMAADLSKRLQRITSQDTDRIQHLFENAGLPVKGPRITPER
YLESMQLDKKVKDGAIRFILLDRIGKASLDNTVPTLLLLETLSACVANA

Sequences:

>Translated_369_residues
MNAMESVEVALDTLPENRSYTIHIGQELLTRIDLLLPHLPGKKAAIVTNTTIAPLYLEKLRSALAEHQVETFAVILPDGE
QYKNWETLNLIFDALLEHRCERKTPLIALGGGVVGDLTGFAAASYLRGVPFIQIPTTLLAQVDSSVGGKTGINHPLGKNM
IGAFYQPRLVLADSATLTTLPDRELRAGIAEVIKYGLIHDADFFDWLERHMQQLLARDPETMNYAIRRSCEIKAEIVSLD
ERESGVRALLNLGHTFGHAIENTMGYGAWLHGEAVAAGTLMAADLSKRLQRITSQDTDRIQHLFENAGLPVKGPRITPER
YLESMQLDKKVKDGAIRFILLDRIGKASLDNTVPTLLLLETLSACVANA
>Mature_369_residues
MNAMESVEVALDTLPENRSYTIHIGQELLTRIDLLLPHLPGKKAAIVTNTTIAPLYLEKLRSALAEHQVETFAVILPDGE
QYKNWETLNLIFDALLEHRCERKTPLIALGGGVVGDLTGFAAASYLRGVPFIQIPTTLLAQVDSSVGGKTGINHPLGKNM
IGAFYQPRLVLADSATLTTLPDRELRAGIAEVIKYGLIHDADFFDWLERHMQQLLARDPETMNYAIRRSCEIKAEIVSLD
ERESGVRALLNLGHTFGHAIENTMGYGAWLHGEAVAAGTLMAADLSKRLQRITSQDTDRIQHLFENAGLPVKGPRITPER
YLESMQLDKKVKDGAIRFILLDRIGKASLDNTVPTLLLLETLSACVANA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=363, Percent_Identity=57.0247933884297, Blast_Score=377, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6320332, Length=374, Percent_Identity=36.3636363636364, Blast_Score=207, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_NITEC (Q0AJ12)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746624.1
- ProteinModelPortal:   Q0AJ12
- SMR:   Q0AJ12
- STRING:   Q0AJ12
- GeneID:   4273492
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0381
- NMPDR:   fig|335283.3.peg.1977
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   Q0AJ12
- ProtClustDB:   PRK00002
- BioCyc:   NEUT335283:NEUT_0381-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40663; Mature: 40663

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAMESVEVALDTLPENRSYTIHIGQELLTRIDLLLPHLPGKKAAIVTNTTIAPLYLEKL
CCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHH
RSALAEHQVETFAVILPDGEQYKNWETLNLIFDALLEHRCERKTPLIALGGGVVGDLTGF
HHHHHHHCCCEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
AAASYLRGVPFIQIPTTLLAQVDSSVGGKTGINHPLGKNMIGAFYQPRLVLADSATLTTL
HHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCEEECC
PDRELRAGIAEVIKYGLIHDADFFDWLERHMQQLLARDPETMNYAIRRSCEIKAEIVSLD
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCC
ERESGVRALLNLGHTFGHAIENTMGYGAWLHGEAVAAGTLMAADLSKRLQRITSQDTDRI
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
QHLFENAGLPVKGPRITPERYLESMQLDKKVKDGAIRFILLDRIGKASLDNTVPTLLLLE
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCCHHHHHHHHHH
TLSACVANA
HHHHHHCCC
>Mature Secondary Structure
MNAMESVEVALDTLPENRSYTIHIGQELLTRIDLLLPHLPGKKAAIVTNTTIAPLYLEKL
CCCHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHH
RSALAEHQVETFAVILPDGEQYKNWETLNLIFDALLEHRCERKTPLIALGGGVVGDLTGF
HHHHHHHCCCEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
AAASYLRGVPFIQIPTTLLAQVDSSVGGKTGINHPLGKNMIGAFYQPRLVLADSATLTTL
HHHHHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCEEECC
PDRELRAGIAEVIKYGLIHDADFFDWLERHMQQLLARDPETMNYAIRRSCEIKAEIVSLD
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCC
ERESGVRALLNLGHTFGHAIENTMGYGAWLHGEAVAAGTLMAADLSKRLQRITSQDTDRI
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
QHLFENAGLPVKGPRITPERYLESMQLDKKVKDGAIRFILLDRIGKASLDNTVPTLLLLE
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHCCCCCCCHHHHHHHHHH
TLSACVANA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA