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The map label for this gene is yheS [H]

Identifier: 114330342

GI number: 114330342

Start: 321686

End: 323599

Strand: Reverse

Name: yheS [H]

Synonym: Neut_0315

Alternate gene names: 114330342

Gene position: 323599-321686 (Counterclockwise)

Preceding gene: 114330346

Following gene: 114330340

Centisome position: 12.16

GC content: 47.96

Gene sequence:

>1914_bases
ATGATACGAATCTCAGAACTAACCCTGCAACGTGGCCCTTTGCGCTTACTAGAAAATGCAGATTTAACCCTACACCCAGG
GCATAAAGTCGGCTTAATTGGTGCCAATGGTGCCGGCAAATCCAGCTTATTCGCCCTGCTGCGCGGCGAACTGCATCCTG
ACGCGGGCGATTGTTTATTGCCGATGAACTGGCGCATTGCCCATATGCGTCAAGAAATCGACGCACCTGATCGTGATGCG
ATTGATTATGTACTCGATGGTGACAGCCACTTACGCGATATTCAACAGCAATTAGCCAAAGCTGAACAACGGCAAGATGG
GGTCGAGCTTGGTCGCTTGTACTCGGAACTTGACAACGCTGATGCCTATACCTCCGACGCGCGCGCGCGTAAATTATTAG
CTGGTTTGGGTTTCTTGGAAGAACAAATGGAAAACCAGGTCAACAGCTTTTCCGGTGGCTGGCGGATGCGCTTAAATCTA
GCGCAAGCATTGATGTGCCCATCAGATTTACTATTACTTGATGAGCCCACCAACCACTTGGACCTCGATGCAATTTTATG
GTTGGAAGGTTGGCTGCAAAACTACTCCGGTACTTTGTTACTGATTTCCCATGACCGTGATTTTTTAGATGCGGTGGTCG
GTCATATTGTCCATATTAATCAGCAAAAACTAACGCTGTATCGCGGCGGCTACACAGCCTTTGAACGCGCCTGTGCTGAA
CGTATTATGCAGCAGCAACAAGCGCACGAAAAACAAAGCGCACAGCGCGCGCATATGGAAGATTTCATCCGACGCTTTAA
AGCCAAGGCCAGTAAAGCACGGCAAGCACAAAGCCGTGTTAAAGCCCTGGAGCGCATGGAGGAGTTGGCGCCAGCACACT
TTGATTCACCTTTTGACTTTATTTTCCGCAAAGCCGATAAAGTCTCTACCCCGCTGCTGAATCTCGATGAAGCAGCGCTT
GGCTACCACGCAGAGCAGCCTATTTTAAGCAATGTAAAACTACAGCTAGTCCCCGGCGCACGGATTGCTTTGCTTGGCCC
CAACGGTGCAGGTAAATCAACGCTGATTAAAAGTATTATGGGTGATTTACCGTTATTGGCAGGCCAGCTCACCTGTAGTG
AAAACTTAGTGATCGGCTACTTTGCTCAGCATCAACTGGATTCACTTGATCCCAAAGCCAGCCCGTTACTGCATTTTCAA
CGCATTGCTCAAGATGAGCACGAGCAAGTCTTGCGTAATTTTCTCGGCGGTTTTAATTTTCGAGGCAAGCGCTGTGATGA
ACCCGTGCTCAATTTCTCTGGTGGTGAAAAAGCCCGCTTAGCTTTGGCACTGATTGCGTGGGGCAAACCTAATTTATTAC
TGCTCGATGAACCCACCAACCACCTTGATTTAGAAATGAGACAAGCATTGAGTATGGCTTTACAAGATTTCTCCGGTGCA
CTACTGCTGGTGTCTCACGATCGTCATCTGATTAAAAGTACCATGGATGAGTTGTACTTAGTCGCCGAGGGCCGGGTACA
AGAGTTTGCAGGTGATCTTGAGGACTACAGCAAATGGCTCAGCGACTATCGTTTGCGCCAGCATCCTAATAGCGATGCAG
GCACCAGCCCCGATAAAGTCGATCGCCGTGCACAACGCCAAGCAGCTGCAGCACTACGTAAACAACTGGCACCGCTACGC
AAGCACACTGATACATTGGAAAAACAGTTAGATAACATTCAAAAAGAGCTACAGGCTTTGGAAACCATCTTGACTGATAA
TAATCTCTATGAGCCGCCACAAAAAGAGCAGCTCAAGCAACACTTAAACCAGCAAACCAACTTGCTACAACAGCAAGTGA
AACTGGAAGAAACCTGGCTCAATAACTTAGAAGAGCTAGAATTATTGCAAAGTGAACTTGAGGAAGATGCATAA

Upstream 100 bases:

>100_bases
GGCATCATTCTTATGGCTACCCTCACTCAAAAGCTCGTAAGACAAACTAAATGGCTCTCTCCATATCAGTAACAGCCGCG
AAACTGCTAAACTGCGCGCC

Downstream 100 bases:

>100_bases
CGCAATGGTTTGAAGAGCTGGCTGAACTGGGTATCACGAAACGCTTGGCCACCCCACTGAATCGCCCCGGCCGGTAGCCA
TACAAGTCCGAAACTATTGA

Product: ABC transporter-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MIRISELTLQRGPLRLLENADLTLHPGHKVGLIGANGAGKSSLFALLRGELHPDAGDCLLPMNWRIAHMRQEIDAPDRDA
IDYVLDGDSHLRDIQQQLAKAEQRQDGVELGRLYSELDNADAYTSDARARKLLAGLGFLEEQMENQVNSFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAILWLEGWLQNYSGTLLLISHDRDFLDAVVGHIVHINQQKLTLYRGGYTAFERACAE
RIMQQQQAHEKQSAQRAHMEDFIRRFKAKASKARQAQSRVKALERMEELAPAHFDSPFDFIFRKADKVSTPLLNLDEAAL
GYHAEQPILSNVKLQLVPGARIALLGPNGAGKSTLIKSIMGDLPLLAGQLTCSENLVIGYFAQHQLDSLDPKASPLLHFQ
RIAQDEHEQVLRNFLGGFNFRGKRCDEPVLNFSGGEKARLALALIAWGKPNLLLLDEPTNHLDLEMRQALSMALQDFSGA
LLLVSHDRHLIKSTMDELYLVAEGRVQEFAGDLEDYSKWLSDYRLRQHPNSDAGTSPDKVDRRAQRQAAAALRKQLAPLR
KHTDTLEKQLDNIQKELQALETILTDNNLYEPPQKEQLKQHLNQQTNLLQQQVKLEETWLNNLEELELLQSELEEDA

Sequences:

>Translated_637_residues
MIRISELTLQRGPLRLLENADLTLHPGHKVGLIGANGAGKSSLFALLRGELHPDAGDCLLPMNWRIAHMRQEIDAPDRDA
IDYVLDGDSHLRDIQQQLAKAEQRQDGVELGRLYSELDNADAYTSDARARKLLAGLGFLEEQMENQVNSFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAILWLEGWLQNYSGTLLLISHDRDFLDAVVGHIVHINQQKLTLYRGGYTAFERACAE
RIMQQQQAHEKQSAQRAHMEDFIRRFKAKASKARQAQSRVKALERMEELAPAHFDSPFDFIFRKADKVSTPLLNLDEAAL
GYHAEQPILSNVKLQLVPGARIALLGPNGAGKSTLIKSIMGDLPLLAGQLTCSENLVIGYFAQHQLDSLDPKASPLLHFQ
RIAQDEHEQVLRNFLGGFNFRGKRCDEPVLNFSGGEKARLALALIAWGKPNLLLLDEPTNHLDLEMRQALSMALQDFSGA
LLLVSHDRHLIKSTMDELYLVAEGRVQEFAGDLEDYSKWLSDYRLRQHPNSDAGTSPDKVDRRAQRQAAAALRKQLAPLR
KHTDTLEKQLDNIQKELQALETILTDNNLYEPPQKEQLKQHLNQQTNLLQQQVKLEETWLNNLEELELLQSELEEDA
>Mature_637_residues
MIRISELTLQRGPLRLLENADLTLHPGHKVGLIGANGAGKSSLFALLRGELHPDAGDCLLPMNWRIAHMRQEIDAPDRDA
IDYVLDGDSHLRDIQQQLAKAEQRQDGVELGRLYSELDNADAYTSDARARKLLAGLGFLEEQMENQVNSFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAILWLEGWLQNYSGTLLLISHDRDFLDAVVGHIVHINQQKLTLYRGGYTAFERACAE
RIMQQQQAHEKQSAQRAHMEDFIRRFKAKASKARQAQSRVKALERMEELAPAHFDSPFDFIFRKADKVSTPLLNLDEAAL
GYHAEQPILSNVKLQLVPGARIALLGPNGAGKSTLIKSIMGDLPLLAGQLTCSENLVIGYFAQHQLDSLDPKASPLLHFQ
RIAQDEHEQVLRNFLGGFNFRGKRCDEPVLNFSGGEKARLALALIAWGKPNLLLLDEPTNHLDLEMRQALSMALQDFSGA
LLLVSHDRHLIKSTMDELYLVAEGRVQEFAGDLEDYSKWLSDYRLRQHPNSDAGTSPDKVDRRAQRQAAAALRKQLAPLR
KHTDTLEKQLDNIQKELQALETILTDNNLYEPPQKEQLKQHLNQQTNLLQQQVKLEETWLNNLEELELLQSELEEDA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=530, Percent_Identity=37.9245283018868, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI27881506, Length=535, Percent_Identity=34.2056074766355, Blast_Score=304, Evalue=2e-82,
Organism=Homo sapiens, GI10947137, Length=535, Percent_Identity=34.2056074766355, Blast_Score=303, Evalue=3e-82,
Organism=Homo sapiens, GI69354671, Length=536, Percent_Identity=34.1417910447761, Blast_Score=268, Evalue=1e-71,
Organism=Homo sapiens, GI10947135, Length=536, Percent_Identity=34.1417910447761, Blast_Score=268, Evalue=1e-71,
Organism=Escherichia coli, GI1789751, Length=632, Percent_Identity=50.7911392405063, Blast_Score=630, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=36.1058601134215, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1787182, Length=605, Percent_Identity=29.0909090909091, Blast_Score=238, Evalue=9e-64,
Organism=Escherichia coli, GI2367384, Length=524, Percent_Identity=28.8167938931298, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788165, Length=194, Percent_Identity=33.5051546391753, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786975, Length=522, Percent_Identity=26.2452107279693, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787758, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787029, Length=202, Percent_Identity=25.7425742574257, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1789891, Length=213, Percent_Identity=26.2910798122066, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788225, Length=215, Percent_Identity=24.1860465116279, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788761, Length=209, Percent_Identity=26.3157894736842, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1789864, Length=233, Percent_Identity=27.4678111587983, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1790467, Length=220, Percent_Identity=23.6363636363636, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI1787164, Length=218, Percent_Identity=28.8990825688073, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=37.3584905660377, Blast_Score=338, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI17559834, Length=550, Percent_Identity=34, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17555318, Length=527, Percent_Identity=33.5863377609108, Blast_Score=295, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI17556528, Length=211, Percent_Identity=26.0663507109005, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=534, Percent_Identity=37.2659176029963, Blast_Score=351, Evalue=2e-97,
Organism=Saccharomyces cerevisiae, GI6320874, Length=532, Percent_Identity=32.3308270676692, Blast_Score=283, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6325030, Length=384, Percent_Identity=32.2916666666667, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6324314, Length=387, Percent_Identity=28.6821705426357, Blast_Score=150, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6323278, Length=387, Percent_Identity=28.1653746770026, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=38.3301707779886, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642252, Length=533, Percent_Identity=37.5234521575985, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI18859989, Length=533, Percent_Identity=37.5234521575985, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24641342, Length=541, Percent_Identity=33.826247689464, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24585557, Length=213, Percent_Identity=26.2910798122066, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45552437, Length=213, Percent_Identity=26.2910798122066, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71908; Mature: 71908

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRISELTLQRGPLRLLENADLTLHPGHKVGLIGANGAGKSSLFALLRGELHPDAGDCLL
CEEEHHHHHCCCCHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEE
PMNWRIAHMRQEIDAPDRDAIDYVLDGDSHLRDIQQQLAKAEQRQDGVELGRLYSELDNA
CCCHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAYTSDARARKLLAGLGFLEEQMENQVNSFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEECCCCCC
DLDAILWLEGWLQNYSGTLLLISHDRDFLDAVVGHIVHINQQKLTLYRGGYTAFERACAE
CHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEECCCCEEEEEECCHHHHHHHHHH
RIMQQQQAHEKQSAQRAHMEDFIRRFKAKASKARQAQSRVKALERMEELAPAHFDSPFDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
IFRKADKVSTPLLNLDEAALGYHAEQPILSNVKLQLVPGARIALLGPNGAGKSTLIKSIM
HHHHHHHHCCCCCCCCHHHHCCCCCCCHHHCCEEEEECCCEEEEECCCCCCHHHHHHHHH
GDLPLLAGQLTCSENLVIGYFAQHQLDSLDPKASPLLHFQRIAQDEHEQVLRNFLGGFNF
CCCHHHHCCCCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCC
RGKRCDEPVLNFSGGEKARLALALIAWGKPNLLLLDEPTNHLDLEMRQALSMALQDFSGA
CCCCCCCCCCCCCCCCHHHEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCE
LLLVSHDRHLIKSTMDELYLVAEGRVQEFAGDLEDYSKWLSDYRLRQHPNSDAGTSPDKV
EEEEECCHHHHHHHHHHHEECCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
DRRAQRQAAAALRKQLAPLRKHTDTLEKQLDNIQKELQALETILTDNNLYEPPQKEQLKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
HLNQQTNLLQQQVKLEETWLNNLEELELLQSELEEDA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRISELTLQRGPLRLLENADLTLHPGHKVGLIGANGAGKSSLFALLRGELHPDAGDCLL
CEEEHHHHHCCCCHHHHCCCCEEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEE
PMNWRIAHMRQEIDAPDRDAIDYVLDGDSHLRDIQQQLAKAEQRQDGVELGRLYSELDNA
CCCHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DAYTSDARARKLLAGLGFLEEQMENQVNSFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCEEEEECCCCCC
DLDAILWLEGWLQNYSGTLLLISHDRDFLDAVVGHIVHINQQKLTLYRGGYTAFERACAE
CHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEECCCCEEEEEECCHHHHHHHHHH
RIMQQQQAHEKQSAQRAHMEDFIRRFKAKASKARQAQSRVKALERMEELAPAHFDSPFDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
IFRKADKVSTPLLNLDEAALGYHAEQPILSNVKLQLVPGARIALLGPNGAGKSTLIKSIM
HHHHHHHHCCCCCCCCHHHHCCCCCCCHHHCCEEEEECCCEEEEECCCCCCHHHHHHHHH
GDLPLLAGQLTCSENLVIGYFAQHQLDSLDPKASPLLHFQRIAQDEHEQVLRNFLGGFNF
CCCHHHHCCCCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCC
RGKRCDEPVLNFSGGEKARLALALIAWGKPNLLLLDEPTNHLDLEMRQALSMALQDFSGA
CCCCCCCCCCCCCCCCHHHEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCE
LLLVSHDRHLIKSTMDELYLVAEGRVQEFAGDLEDYSKWLSDYRLRQHPNSDAGTSPDKV
EEEEECCHHHHHHHHHHHEECCCCHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
DRRAQRQAAAALRKQLAPLRKHTDTLEKQLDNIQKELQALETILTDNNLYEPPQKEQLKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
HLNQQTNLLQQQVKLEETWLNNLEELELLQSELEEDA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]