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The map label for this gene is tolQ [H]

Identifier: 114330313

GI number: 114330313

Start: 296136

End: 296840

Strand: Direct

Name: tolQ [H]

Synonym: Neut_0286

Alternate gene names: 114330313

Gene position: 296136-296840 (Clockwise)

Preceding gene: 114330312

Following gene: 114330314

Centisome position: 11.13

GC content: 48.65

Gene sequence:

>705_bases
ATGAGTAAAACCATCACCCAGGATTTATCATTTCTTCACCTGATTAGCGGTGCAAGCCTCCCGGTTCAACTGGTTATGCT
GCTATTGTTGTTGGCTTCATTTATTTCCTGGTGGTTTATTTTCAGAAAATTATTTACCCTCCGTCAGGAAATCAAGCAAA
CCGATGAATTTGAAAGCGTATTCTGGCGCGGATCAGATTTGAATGCGCTGTATCAGCGAGCGGCCAGTGCGCGCCATGCA
GCAGGTAGTATGGAGCGTATTTTTGAAGCTGGATTTCGTGAATTCACCAAATACCAGTCGGGGATCGATATCGGTCCCAT
CATGGACAGTACGCGCGGCGCAATGCGAGCTGTTTACCAGCGGGAAATGGACAGACTTGAATCACATTTATCGTTTCTGG
CTACTGTAGGATCTGTAAGCCCGTACGTAGGATTGTTCGGAACGGTGTGGGGGATTATGAATGCCTTTCGTGAGCTGTCC
AATGTTGGTCAGGCGACCATCGCGCATGTTGCGCCTGGTATTGCTGAGGCGCTGATTGCAACGGCAATGGGGCTTTTTGC
AGCGATTCCGGCCGTGATTGCCTATAACCGCTATGCTAGTGATACCGCTCAGCTCGCCACTCGCTATGAAAGTTTTATAG
AGGAAGTATCCAACGTTTTGCAGCGTCGTGTGGCCAAACCTCGGGATATGGCAAATTTCTCATGA

Upstream 100 bases:

>100_bases
CTTGCCAGCGCAACTGTTCATGCAGTATGTGTCGGATCGGATACGTTGAAACCGATTAGTATTCCAGTGCCACTTCGTCA
AAAAATAGAAAACGGCCATC

Downstream 100 bases:

>100_bases
TTCCGCGTCGCAGTAAACGCCGATTAATGAATGAAATAAATGTTGTGCCATATATTGACGTTATGCTGGTGCTGCTTATA
ATTTTCATGATCACAGCACC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSKTITQDLSFLHLISGASLPVQLVMLLLLLASFISWWFIFRKLFTLRQEIKQTDEFESVFWRGSDLNALYQRAASARHA
AGSMERIFEAGFREFTKYQSGIDIGPIMDSTRGAMRAVYQREMDRLESHLSFLATVGSVSPYVGLFGTVWGIMNAFRELS
NVGQATIAHVAPGIAEALIATAMGLFAAIPAVIAYNRYASDTAQLATRYESFIEEVSNVLQRRVAKPRDMANFS

Sequences:

>Translated_234_residues
MSKTITQDLSFLHLISGASLPVQLVMLLLLLASFISWWFIFRKLFTLRQEIKQTDEFESVFWRGSDLNALYQRAASARHA
AGSMERIFEAGFREFTKYQSGIDIGPIMDSTRGAMRAVYQREMDRLESHLSFLATVGSVSPYVGLFGTVWGIMNAFRELS
NVGQATIAHVAPGIAEALIATAMGLFAAIPAVIAYNRYASDTAQLATRYESFIEEVSNVLQRRVAKPRDMANFS
>Mature_233_residues
SKTITQDLSFLHLISGASLPVQLVMLLLLLASFISWWFIFRKLFTLRQEIKQTDEFESVFWRGSDLNALYQRAASARHAA
GSMERIFEAGFREFTKYQSGIDIGPIMDSTRGAMRAVYQREMDRLESHLSFLATVGSVSPYVGLFGTVWGIMNAFRELSN
VGQATIAHVAPGIAEALIATAMGLFAAIPAVIAYNRYASDTAQLATRYESFIEEVSNVLQRRVAKPRDMANFS

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=218, Percent_Identity=46.3302752293578, Blast_Score=186, Evalue=8e-49,
Organism=Escherichia coli, GI1789381, Length=211, Percent_Identity=34.5971563981043, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26136; Mature: 26005

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTITQDLSFLHLISGASLPVQLVMLLLLLASFISWWFIFRKLFTLRQEIKQTDEFESV
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWRGSDLNALYQRAASARHAAGSMERIFEAGFREFTKYQSGIDIGPIMDSTRGAMRAVYQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
REMDRLESHLSFLATVGSVSPYVGLFGTVWGIMNAFRELSNVGQATIAHVAPGIAEALIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAMGLFAAIPAVIAYNRYASDTAQLATRYESFIEEVSNVLQRRVAKPRDMANFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SKTITQDLSFLHLISGASLPVQLVMLLLLLASFISWWFIFRKLFTLRQEIKQTDEFESV
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWRGSDLNALYQRAASARHAAGSMERIFEAGFREFTKYQSGIDIGPIMDSTRGAMRAVYQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
REMDRLESHLSFLATVGSVSPYVGLFGTVWGIMNAFRELSNVGQATIAHVAPGIAEALIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAMGLFAAIPAVIAYNRYASDTAQLATRYESFIEEVSNVLQRRVAKPRDMANFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]