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The map label for this gene is sucD [H]

Identifier: 114330249

GI number: 114330249

Start: 228497

End: 229372

Strand: Direct

Name: sucD [H]

Synonym: Neut_0221

Alternate gene names: 114330249

Gene position: 228497-229372 (Clockwise)

Preceding gene: 114330248

Following gene: 114330250

Centisome position: 8.59

GC content: 48.17

Gene sequence:

>876_bases
ATGGCTATTCTGATTGATCGTCATACGCGTGTCATGACACAGGGTATTACAGGTAAAACCGGGCAGTTTCATACTCGCCA
GTGCCGAGAATATGCTTTTGGCAGGGATTGTTTTGTGGCTGGAGTCAATCCTAAAAAGGCAGGAGAGGATTTTGAAGGTA
TTCCGGTGTTTGCAACAGTGGAAGCAGCAAGGCAGACGACGGGTGCGACTGTATCGGTGATTTATGTGCCGCCTGCTTAT
GCAGCTGCAGCAATTGATGAGGCGGTGGAGGCCGAACTGGATCTGGTCATCTGCATTACTGAAGGTATTCCTGTTCGAGA
TATGTTGCGGACACGCGCCCGTATGCGTGGAAAAAAGACACAGTTGATCGGTCCTAATTGTCCGGGAGTTATCACGCCAG
GTGAGTTGAAAATTGGCATTATGCCAGGCGCCATTCATCAACAAGGAAGGATTGGGGTGGTTTCAAGATCAGGTACGTTA
ACTTATGAGGCAGTGGCGCAGCTGAGTGAGCTGGGATTAGGGCAATCTACTTGCATCGGAATTGGTGGTGATCCGATCAA
TGGTCTTAAACATATTGATATCCTAAAGTTGTTCAATGAGGATGACGGAACTGATGCGGTGTTGATGGTGGGTGAAATTG
GTGGTACTGATGAGGAAGAATCTGCTCATTGGGTTAAAGATCATATGAAGAAGCCGGTGGTGGGGTTTGTTGCCGGAATG
ACAGCGCCTCCCGGCAAACGGATGGGGCATGCAGGTGCAATTATTGCTGGAGGCAAAGGAACAGCACAGGAAAAAATTGA
AGTAATGGAGGCATGTGGTATTCATGTTGCCCGCAATCCAGCTGAAATGGGCAAGCTATTGAAAACAGTGATATAG

Upstream 100 bases:

>100_bases
AACGATTATTGCTGGCAGCAACATGGCTGATGCTGCCAGAAAGGCGGTGGATGCAGCAGCTCGGCATCGATCTGAAGCTG
CAACCAGAGGAGCATAACAG

Downstream 100 bases:

>100_bases
CAAAAAATAAAATATAACGAATAAAAGGGAGTGAAAAATGCTGCGAGTAAATGTTGTTGCGATAGTAATTGCTTTATTGG
CAGGCTGTACGATGGCTAAG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MAILIDRHTRVMTQGITGKTGQFHTRQCREYAFGRDCFVAGVNPKKAGEDFEGIPVFATVEAARQTTGATVSVIYVPPAY
AAAAIDEAVEAELDLVICITEGIPVRDMLRTRARMRGKKTQLIGPNCPGVITPGELKIGIMPGAIHQQGRIGVVSRSGTL
TYEAVAQLSELGLGQSTCIGIGGDPINGLKHIDILKLFNEDDGTDAVLMVGEIGGTDEEESAHWVKDHMKKPVVGFVAGM
TAPPGKRMGHAGAIIAGGKGTAQEKIEVMEACGIHVARNPAEMGKLLKTVI

Sequences:

>Translated_291_residues
MAILIDRHTRVMTQGITGKTGQFHTRQCREYAFGRDCFVAGVNPKKAGEDFEGIPVFATVEAARQTTGATVSVIYVPPAY
AAAAIDEAVEAELDLVICITEGIPVRDMLRTRARMRGKKTQLIGPNCPGVITPGELKIGIMPGAIHQQGRIGVVSRSGTL
TYEAVAQLSELGLGQSTCIGIGGDPINGLKHIDILKLFNEDDGTDAVLMVGEIGGTDEEESAHWVKDHMKKPVVGFVAGM
TAPPGKRMGHAGAIIAGGKGTAQEKIEVMEACGIHVARNPAEMGKLLKTVI
>Mature_290_residues
AILIDRHTRVMTQGITGKTGQFHTRQCREYAFGRDCFVAGVNPKKAGEDFEGIPVFATVEAARQTTGATVSVIYVPPAYA
AAAIDEAVEAELDLVICITEGIPVRDMLRTRARMRGKKTQLIGPNCPGVITPGELKIGIMPGAIHQQGRIGVVSRSGTLT
YEAVAQLSELGLGQSTCIGIGGDPINGLKHIDILKLFNEDDGTDAVLMVGEIGGTDEEESAHWVKDHMKKPVVGFVAGMT
APPGKRMGHAGAIIAGGKGTAQEKIEVMEACGIHVARNPAEMGKLLKTVI

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=57.4912891986063, Blast_Score=279, Evalue=2e-75,
Organism=Homo sapiens, GI38569423, Length=254, Percent_Identity=28.3464566929134, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38569421, Length=254, Percent_Identity=28.3464566929134, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786949, Length=291, Percent_Identity=56.3573883161512, Blast_Score=330, Evalue=5e-92,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=53.7671232876712, Blast_Score=302, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17553126, Length=294, Percent_Identity=52.3809523809524, Blast_Score=294, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI17557344, Length=249, Percent_Identity=26.5060240963855, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=301, Percent_Identity=25.5813953488372, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=47.6190476190476, Blast_Score=256, Evalue=2e-69,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=48.9583333333333, Blast_Score=287, Evalue=7e-78,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=53.125, Blast_Score=270, Evalue=9e-73,
Organism=Drosophila melanogaster, GI281363477, Length=251, Percent_Identity=27.4900398406374, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363475, Length=251, Percent_Identity=27.4900398406374, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363473, Length=251, Percent_Identity=27.4900398406374, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30808; Mature: 30677

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILIDRHTRVMTQGITGKTGQFHTRQCREYAFGRDCFVAGVNPKKAGEDFEGIPVFATV
CEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCEEEEEE
EAARQTTGATVSVIYVPPAYAAAAIDEAVEAELDLVICITEGIPVRDMLRTRARMRGKKT
HHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCE
QLIGPNCPGVITPGELKIGIMPGAIHQQGRIGVVSRSGTLTYEAVAQLSELGLGQSTCIG
EEECCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEE
IGGDPINGLKHIDILKLFNEDDGTDAVLMVGEIGGTDEEESAHWVKDHMKKPVVGFVAGM
CCCCCCCCCHHHHEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHCC
TAPPGKRMGHAGAIIAGGKGTAQEKIEVMEACGIHVARNPAEMGKLLKTVI
CCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHC
>Mature Secondary Structure 
AILIDRHTRVMTQGITGKTGQFHTRQCREYAFGRDCFVAGVNPKKAGEDFEGIPVFATV
EEEEECCHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCCHHHCCCCCCCCEEEEEE
EAARQTTGATVSVIYVPPAYAAAAIDEAVEAELDLVICITEGIPVRDMLRTRARMRGKKT
HHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHCCCCE
QLIGPNCPGVITPGELKIGIMPGAIHQQGRIGVVSRSGTLTYEAVAQLSELGLGQSTCIG
EEECCCCCCEECCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEEE
IGGDPINGLKHIDILKLFNEDDGTDAVLMVGEIGGTDEEESAHWVKDHMKKPVVGFVAGM
CCCCCCCCCHHHHEEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHCC
TAPPGKRMGHAGAIIAGGKGTAQEKIEVMEACGIHVARNPAEMGKLLKTVI
CCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]