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The map label for this gene is sucC [H]

Identifier: 114330248

GI number: 114330248

Start: 227300

End: 228493

Strand: Direct

Name: sucC [H]

Synonym: Neut_0220

Alternate gene names: 114330248

Gene position: 227300-228493 (Clockwise)

Preceding gene: 114330247

Following gene: 114330249

Centisome position: 8.54

GC content: 48.99

Gene sequence:

>1194_bases
ATGAAAATTCATGAATACCAGGCTAAAGCAATTCTTAGCCGTTATGCGATTAGTGTGCCGGCCGGTATTGCTTGTTTTAG
CGTGGAGGAAGCGATTCTGGCTGCTGAAAAGCTGGGGGGTGATAAATGGGTGGTCAAGGCACAAATTTATGCTGGAGGGC
GTGGCAAGGCAGGGGGGGTAAAGCTGGCAAAGTCCATTGTGGAGGTCCGGCAGTTTTCTGAGGCGATGTTGTTTGCTCCG
CTGGTCACGCATCAAACCGGCCCACAGGGACAGATTGTTCGCCGGCTCTATATTGAACAGGGGATCGATATCAGTCATGA
GTATTACGTGGCACTGGTTGTTGATCGTGCTTCGCAGTGTGTCAGTTTAATTGCGAGTGATGCGGGTGGCATGGATATTG
AGGGGGTGGCAACCAGTACACCAGAAAAAATACATAAAACTCAGATTAATCCGCTTGAGGGATTGAATCTTCAAGATGCA
GAGAGAGTTGTGCGCCAGATCAATTTGCCTGAATCATGCCGATCAGCGGCGGTGTCTATGCTGGGGGCGCTATATCAGGC
ATTCGATGAGAACGATATTTCATTACTTGAAATCAATCCGTTGATTGTTACACCAGATAACCGTCTGATTGCTTTGGACG
CCAAAATGAATTTCGATGATAACGCCTTGTTTCGTCATCCGGAAATCGTTGCCCTGCGGGATCTGGATGAAGATGATCCG
CTTGAGGTTGAAGCAGCGCGGCATGGGCTTTCCTATATTCCGCTTGATGGTGATATTGGCTGTCTAGTCAACGGTGCTGG
TTTGGCTATGGCAACCATGGACATTATTAAACTCTATGGTGGCAATCCAGCCAATTTTCTGGATGTGGGAGGCGGAGCGA
CGGTGGAAAAAGTAACTGAGGCATTCAAGCTGATGCTGAGAAATCCCGATTTGCAGGCAATACTGGTCAATATTTTTGGT
GGGATTATGCGCTGCGATGTAATTGCTGATGGGGTGGTGTCAGCGGTGCGCGAGGTGAAGCTAGCTGTTCCATTGATTGT
TCGATTGGAGGGAACCAATGTGGAGTTGGGGAAAAAGATTCTGGCAGATTCGGGATTAACGATTATTGCTGGCAGCAACA
TGGCTGATGCTGCCAGAAAGGCGGTGGATGCAGCAGCTCGGCATCGATCTGAAGCTGCAACCAGAGGAGCATAA

Upstream 100 bases:

>100_bases
CTAGGCTATTGCCTGGCTTTAAACAAGAGCTGGCCGAAGTGGGGAGTTATATTAAGAAGGTATTGGCACAACCCGATGTG
TGAGCGCAAAAGGATGAAAT

Downstream 100 bases:

>100_bases
CAGATGGCTATTCTGATTGATCGTCATACGCGTGTCATGACACAGGGTATTACAGGTAAAACCGGGCAGTTTCATACTCG
CCAGTGCCGAGAATATGCTT

Product: succinyl-CoA synthetase, beta subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKIHEYQAKAILSRYAISVPAGIACFSVEEAILAAEKLGGDKWVVKAQIYAGGRGKAGGVKLAKSIVEVRQFSEAMLFAP
LVTHQTGPQGQIVRRLYIEQGIDISHEYYVALVVDRASQCVSLIASDAGGMDIEGVATSTPEKIHKTQINPLEGLNLQDA
ERVVRQINLPESCRSAAVSMLGALYQAFDENDISLLEINPLIVTPDNRLIALDAKMNFDDNALFRHPEIVALRDLDEDDP
LEVEAARHGLSYIPLDGDIGCLVNGAGLAMATMDIIKLYGGNPANFLDVGGGATVEKVTEAFKLMLRNPDLQAILVNIFG
GIMRCDVIADGVVSAVREVKLAVPLIVRLEGTNVELGKKILADSGLTIIAGSNMADAARKAVDAAARHRSEAATRGA

Sequences:

>Translated_397_residues
MKIHEYQAKAILSRYAISVPAGIACFSVEEAILAAEKLGGDKWVVKAQIYAGGRGKAGGVKLAKSIVEVRQFSEAMLFAP
LVTHQTGPQGQIVRRLYIEQGIDISHEYYVALVVDRASQCVSLIASDAGGMDIEGVATSTPEKIHKTQINPLEGLNLQDA
ERVVRQINLPESCRSAAVSMLGALYQAFDENDISLLEINPLIVTPDNRLIALDAKMNFDDNALFRHPEIVALRDLDEDDP
LEVEAARHGLSYIPLDGDIGCLVNGAGLAMATMDIIKLYGGNPANFLDVGGGATVEKVTEAFKLMLRNPDLQAILVNIFG
GIMRCDVIADGVVSAVREVKLAVPLIVRLEGTNVELGKKILADSGLTIIAGSNMADAARKAVDAAARHRSEAATRGA
>Mature_397_residues
MKIHEYQAKAILSRYAISVPAGIACFSVEEAILAAEKLGGDKWVVKAQIYAGGRGKAGGVKLAKSIVEVRQFSEAMLFAP
LVTHQTGPQGQIVRRLYIEQGIDISHEYYVALVVDRASQCVSLIASDAGGMDIEGVATSTPEKIHKTQINPLEGLNLQDA
ERVVRQINLPESCRSAAVSMLGALYQAFDENDISLLEINPLIVTPDNRLIALDAKMNFDDNALFRHPEIVALRDLDEDDP
LEVEAARHGLSYIPLDGDIGCLVNGAGLAMATMDIIKLYGGNPANFLDVGGGATVEKVTEAFKLMLRNPDLQAILVNIFG
GIMRCDVIADGVVSAVREVKLAVPLIVRLEGTNVELGKKILADSGLTIIAGSNMADAARKAVDAAARHRSEAATRGA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=45.2442159383033, Blast_Score=334, Evalue=8e-92,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=44.6475195822454, Blast_Score=325, Evalue=7e-89,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=44.7513812154696, Blast_Score=308, Evalue=8e-84,
Organism=Escherichia coli, GI1786948, Length=384, Percent_Identity=51.0416666666667, Blast_Score=379, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=43.5114503816794, Blast_Score=317, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=43.5897435897436, Blast_Score=315, Evalue=3e-86,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=44.0203562340967, Blast_Score=334, Evalue=2e-92,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=45.4081632653061, Blast_Score=321, Evalue=7e-88,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=45.4081632653061, Blast_Score=321, Evalue=7e-88,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=45.29262086514, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=45.29262086514, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=42.0918367346939, Blast_Score=301, Evalue=5e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42464; Mature: 42464

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQAKAILSRYAISVPAGIACFSVEEAILAAEKLGGDKWVVKAQIYAGGRGKAGGV
CCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHH
KLAKSIVEVRQFSEAMLFAPLVTHQTGPQGQIVRRLYIEQGIDISHEYYVALVVDRASQC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHH
VSLIASDAGGMDIEGVATSTPEKIHKTQINPLEGLNLQDAERVVRQINLPESCRSAAVSM
HHHHHCCCCCCEECCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
LGALYQAFDENDISLLEINPLIVTPDNRLIALDAKMNFDDNALFRHPEIVALRDLDEDDP
HHHHHHHHCCCCEEEEEECCEEECCCCCEEEEEEECCCCCCCEECCCCEEEEECCCCCCC
LEVEAARHGLSYIPLDGDIGCLVNGAGLAMATMDIIKLYGGNPANFLDVGGGATVEKVTE
CCHHHHHCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKLMLRNPDLQAILVNIFGGIMRCDVIADGVVSAVREVKLAVPLIVRLEGTNVELGKKI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHH
LADSGLTIIAGSNMADAARKAVDAAARHRSEAATRGA
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIHEYQAKAILSRYAISVPAGIACFSVEEAILAAEKLGGDKWVVKAQIYAGGRGKAGGV
CCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHH
KLAKSIVEVRQFSEAMLFAPLVTHQTGPQGQIVRRLYIEQGIDISHEYYVALVVDRASQC
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHH
VSLIASDAGGMDIEGVATSTPEKIHKTQINPLEGLNLQDAERVVRQINLPESCRSAAVSM
HHHHHCCCCCCEECCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
LGALYQAFDENDISLLEINPLIVTPDNRLIALDAKMNFDDNALFRHPEIVALRDLDEDDP
HHHHHHHHCCCCEEEEEECCEEECCCCCEEEEEEECCCCCCCEECCCCEEEEECCCCCCC
LEVEAARHGLSYIPLDGDIGCLVNGAGLAMATMDIIKLYGGNPANFLDVGGGATVEKVTE
CCHHHHHCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKLMLRNPDLQAILVNIFGGIMRCDVIADGVVSAVREVKLAVPLIVRLEGTNVELGKKI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHH
LADSGLTIIAGSNMADAARKAVDAAARHRSEAATRGA
HHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA