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The map label for this gene is pucG [H]

Identifier: 114330229

GI number: 114330229

Start: 202719

End: 203933

Strand: Reverse

Name: pucG [H]

Synonym: Neut_0200

Alternate gene names: 114330229

Gene position: 203933-202719 (Counterclockwise)

Preceding gene: 114330230

Following gene: 114330228

Centisome position: 7.66

GC content: 45.84

Gene sequence:

>1215_bases
ATGACCATTGATAGCTTTCGCCCAGAAAAAAAAATAACCACTTTCTATCCGCCTCAGCGCACCTTGCTTGGTCCGGGACC
ATCCGATACACACGCGCGTGTTTTATCCGCTATGGCTCGCCCGACACTGGGTCACCTTGATCCGGTTTTCACCGAAATGA
TGGAAGAATTGAAAGGCTTGCTGCGATATGTATTTCAAACGACCAATTTATTGACTTTTCCAGTTTCCGGACCGGGTTCG
GTCGGAATGGAAATGTGTTTTGTTAACATGATTGTGCCTGGAGACAAAGTTGTTGTTTGCAGAAATGGTGTCTTTGGCGG
ACGGATGATCGAGAATGTCGAACGCTGTGGCGGAATTCCATTGGTAGTGGAGGATAAATGGGGCGATCCGGTTGATCCTC
AAAAAGTGGAAGATATACTGAAAAAGAATCCGGATGCTAAAATTGTGGCGTTTGTACATGCCGAAACTTCTACAGGTGTT
CAGTCGGATGCCAAGACCATCGGCCAAATAGCAAGAAAGTACGATTGCCTAACAATTATGGACACTGTCACGTCATTAGG
CGGGACACCTGTTTATATGGATGGATGGGATATTGATGCCATTTATTCCGGCAGCCAGAAATGTTTATCCTGTCCACCGG
GATTGTCTCCCGTCAGTTTTTCAGAAAGAGTAGTAGATCTGGTCAGGAATCGTACTGAAAAAGTACACAGCTGGTTCATG
GATATCAGTTTGTTACTCGGTTACTGGGGATCTTCCCGCACCTATCATCACACCGCACCAACCAATTCTCTATATGGCTT
GCATGAATCACTGATTATATTGTATGAAGAAGGGCTTGAGCATTCCTGGACCCGGCATCGTCGTAATCACGAAGCATTAA
AAGCTGGATTGAAAACACTGGGTATCGGATATGTCGTGGATGAAGCATATCGTCTGCCACAGTTGAACTCTGTGCATGTC
CCGACGGGCGTAGATGAAAAAGAAGTACGCCGCAGGCTCTTGGCTGATTACAATCTAGAAATTGGTGCTGGTTTAGGTGA
TTTTGCCGGAAAAATCTGGCGCATCGGCTTGATGGGTAATTCAAGCAAACTGGAAAACGTCATATTCTGCCTGGATGCAT
TAGAGCATGTATTGGCCGATTTGGGCACGAAAGTCGATAAAGGTGCAGCATCATCTGCTGCGCATCAATATTATGCAAAT
AATCCCGCTGTATAG

Upstream 100 bases:

>100_bases
CCACCAGTAGGCTATTTGATATTTCCCTGAAGATTCTGGTTACTGATAGAAACCGGATTCTAGAGAACAACATTTTCATT
CACTCATATTAGGAATATCG

Downstream 100 bases:

>100_bases
GTGACTGGTAGAGCTGCTGCTAAAAAGTAAATTTCTCCATTTTGTAACAGGAGAAATTTACTGCTCCGGCGAAAAACTAA
ATTTTTGCTCGCATTTTCTG

Product: alanine--glyoxylate transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTIDSFRPEKKITTFYPPQRTLLGPGPSDTHARVLSAMARPTLGHLDPVFTEMMEELKGLLRYVFQTTNLLTFPVSGPGS
VGMEMCFVNMIVPGDKVVVCRNGVFGGRMIENVERCGGIPLVVEDKWGDPVDPQKVEDILKKNPDAKIVAFVHAETSTGV
QSDAKTIGQIARKYDCLTIMDTVTSLGGTPVYMDGWDIDAIYSGSQKCLSCPPGLSPVSFSERVVDLVRNRTEKVHSWFM
DISLLLGYWGSSRTYHHTAPTNSLYGLHESLIILYEEGLEHSWTRHRRNHEALKAGLKTLGIGYVVDEAYRLPQLNSVHV
PTGVDEKEVRRRLLADYNLEIGAGLGDFAGKIWRIGLMGNSSKLENVIFCLDALEHVLADLGTKVDKGAASSAAHQYYAN
NPAV

Sequences:

>Translated_404_residues
MTIDSFRPEKKITTFYPPQRTLLGPGPSDTHARVLSAMARPTLGHLDPVFTEMMEELKGLLRYVFQTTNLLTFPVSGPGS
VGMEMCFVNMIVPGDKVVVCRNGVFGGRMIENVERCGGIPLVVEDKWGDPVDPQKVEDILKKNPDAKIVAFVHAETSTGV
QSDAKTIGQIARKYDCLTIMDTVTSLGGTPVYMDGWDIDAIYSGSQKCLSCPPGLSPVSFSERVVDLVRNRTEKVHSWFM
DISLLLGYWGSSRTYHHTAPTNSLYGLHESLIILYEEGLEHSWTRHRRNHEALKAGLKTLGIGYVVDEAYRLPQLNSVHV
PTGVDEKEVRRRLLADYNLEIGAGLGDFAGKIWRIGLMGNSSKLENVIFCLDALEHVLADLGTKVDKGAASSAAHQYYAN
NPAV
>Mature_403_residues
TIDSFRPEKKITTFYPPQRTLLGPGPSDTHARVLSAMARPTLGHLDPVFTEMMEELKGLLRYVFQTTNLLTFPVSGPGSV
GMEMCFVNMIVPGDKVVVCRNGVFGGRMIENVERCGGIPLVVEDKWGDPVDPQKVEDILKKNPDAKIVAFVHAETSTGVQ
SDAKTIGQIARKYDCLTIMDTVTSLGGTPVYMDGWDIDAIYSGSQKCLSCPPGLSPVSFSERVVDLVRNRTEKVHSWFMD
ISLLLGYWGSSRTYHHTAPTNSLYGLHESLIILYEEGLEHSWTRHRRNHEALKAGLKTLGIGYVVDEAYRLPQLNSVHVP
TGVDEKEVRRRLLADYNLEIGAGLGDFAGKIWRIGLMGNSSKLENVIFCLDALEHVLADLGTKVDKGAASSAAHQYYANN
PAV

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=375, Percent_Identity=38.4, Blast_Score=262, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI17536281, Length=373, Percent_Identity=41.2868632707775, Blast_Score=272, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6321079, Length=380, Percent_Identity=27.8947368421053, Blast_Score=115, Evalue=8e-27,
Organism=Drosophila melanogaster, GI17530823, Length=379, Percent_Identity=38.7862796833773, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 44567; Mature: 44435

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDSFRPEKKITTFYPPQRTLLGPGPSDTHARVLSAMARPTLGHLDPVFTEMMEELKGL
CCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LRYVFQTTNLLTFPVSGPGSVGMEMCFVNMIVPGDKVVVCRNGVFGGRMIENVERCGGIP
HHHHHHHCCEEEEECCCCCHHHHHHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCE
LVVEDKWGDPVDPQKVEDILKKNPDAKIVAFVHAETSTGVQSDAKTIGQIARKYDCLTIM
EEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
DTVTSLGGTPVYMDGWDIDAIYSGSQKCLSCPPGLSPVSFSERVVDLVRNRTEKVHSWFM
HHHHHCCCCEEEECCCCCCCEECCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DISLLLGYWGSSRTYHHTAPTNSLYGLHESLIILYEEGLEHSWTRHRRNHEALKAGLKTL
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHEEEEEHHCCCHHHHHHHHHHHHHHHHHHHH
GIGYVVDEAYRLPQLNSVHVPTGVDEKEVRRRLLADYNLEIGAGLGDFAGKIWRIGLMGN
CHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHCCCCEECCCCHHHCCCEEEEEECCC
SSKLENVIFCLDALEHVLADLGTKVDKGAASSAAHQYYANNPAV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TIDSFRPEKKITTFYPPQRTLLGPGPSDTHARVLSAMARPTLGHLDPVFTEMMEELKGL
CCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LRYVFQTTNLLTFPVSGPGSVGMEMCFVNMIVPGDKVVVCRNGVFGGRMIENVERCGGIP
HHHHHHHCCEEEEECCCCCHHHHHHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCCE
LVVEDKWGDPVDPQKVEDILKKNPDAKIVAFVHAETSTGVQSDAKTIGQIARKYDCLTIM
EEEECCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
DTVTSLGGTPVYMDGWDIDAIYSGSQKCLSCPPGLSPVSFSERVVDLVRNRTEKVHSWFM
HHHHHCCCCEEEECCCCCCCEECCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DISLLLGYWGSSRTYHHTAPTNSLYGLHESLIILYEEGLEHSWTRHRRNHEALKAGLKTL
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHEEEEEHHCCCHHHHHHHHHHHHHHHHHHHH
GIGYVVDEAYRLPQLNSVHVPTGVDEKEVRRRLLADYNLEIGAGLGDFAGKIWRIGLMGN
CHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHCCCCEECCCCHHHCCCEEEEEECCC
SSKLENVIFCLDALEHVLADLGTKVDKGAASSAAHQYYANNPAV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]