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The map label for this gene is motA [H]

Identifier: 114330217

GI number: 114330217

Start: 188750

End: 189610

Strand: Direct

Name: motA [H]

Synonym: Neut_0188

Alternate gene names: 114330217

Gene position: 188750-189610 (Clockwise)

Preceding gene: 114330215

Following gene: 114330218

Centisome position: 7.09

GC content: 50.41

Gene sequence:

>861_bases
ATGTTGGTAACTATCGGATATCTTATTGTCATTGTCTCCGTGTTTGGTGGATTTGCTCTGGCGGGCGGCCATCTGGGATC
ATTATTTCAGCCGGTCGAGCTGCTCATGATTGCAGGTGCCGCGCTGGGTGCATTCTTCGTCGGTAATTCCGGCAAAGCAA
TCAAGGCTACTTTCAAAGCGCTTCCTGGTGTTTTTCAGGGTGCCCGATATACCAAGGTGGTCTACATGGAGCTGATGACA
CTGCTCTATGAAGTGCTCGGCAAAATCCGCAAGGAAGGGCTGATGTCGATTGAGGCGGATGTGGATGATCCTGCTAAAAG
TCCGTTGTTCACAAAATATCCCAAAATCCTGTCGGATCATCATGCCATAGAATTCATTACCGATTATCTGCGGCTGATGG
TTGGCGGTAATCTTAACCCCCTGGAAATTGAAAATCTGATGGATGGTGAAATCGAAACGCATCACCAGGAAGGGGAGGTG
CCTGTGCATGTTATCGGCAAGATGGGGGATGCACTCCCGGCTTTCGGAATTGTGGCAGCCGTGATGGGTGTGGTGCATAC
CATGGCGTCAGTCGGCATTCCACCGGCAGAGCTGGGCAAGTTGATTGCTGCGGCATTGGTTGGGACGTTTCTTGGGATTT
TGCTTGCCTATGGTTTTGTCAGCCCTCTAGCCAGTCGCCTGGAACAGAGATTGCATGAATCAAGCAAGTTGCTGGAGTGC
ATCAAGGTTACGCTGCTGGCTAATCTCAACGGCTATGCACCGGCTCTGGCAGTGGAATTTGGCAGGAAAGTACTATTCTC
CACCGAGCGGCCATCGTTCATCGAACTGGAAAAACACGTCAAACAGAGTAAAGCTAAATGA

Upstream 100 bases:

>100_bases
CCATTGGTACTGGCCTGATATCCAGCTGGTGTGGTTACCCGATTAAAGTCAGCCCGCAAGCAGCCGATAAAGTCTGAAAT
TCATAAAAGGTTTTTCAGTC

Downstream 100 bases:

>100_bases
TGTTGCTTCTCCAAGTTTTTCTGTTGCTAAGTGAGGTCGTGAATGGCTGAGGATTTTTCACAAAAACCCATCATTATCAA
ACGTATTAAGAAGGTGTCGG

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLVTIGYLIVIVSVFGGFALAGGHLGSLFQPVELLMIAGAALGAFFVGNSGKAIKATFKALPGVFQGARYTKVVYMELMT
LLYEVLGKIRKEGLMSIEADVDDPAKSPLFTKYPKILSDHHAIEFITDYLRLMVGGNLNPLEIENLMDGEIETHHQEGEV
PVHVIGKMGDALPAFGIVAAVMGVVHTMASVGIPPAELGKLIAAALVGTFLGILLAYGFVSPLASRLEQRLHESSKLLEC
IKVTLLANLNGYAPALAVEFGRKVLFSTERPSFIELEKHVKQSKAK

Sequences:

>Translated_286_residues
MLVTIGYLIVIVSVFGGFALAGGHLGSLFQPVELLMIAGAALGAFFVGNSGKAIKATFKALPGVFQGARYTKVVYMELMT
LLYEVLGKIRKEGLMSIEADVDDPAKSPLFTKYPKILSDHHAIEFITDYLRLMVGGNLNPLEIENLMDGEIETHHQEGEV
PVHVIGKMGDALPAFGIVAAVMGVVHTMASVGIPPAELGKLIAAALVGTFLGILLAYGFVSPLASRLEQRLHESSKLLEC
IKVTLLANLNGYAPALAVEFGRKVLFSTERPSFIELEKHVKQSKAK
>Mature_286_residues
MLVTIGYLIVIVSVFGGFALAGGHLGSLFQPVELLMIAGAALGAFFVGNSGKAIKATFKALPGVFQGARYTKVVYMELMT
LLYEVLGKIRKEGLMSIEADVDDPAKSPLFTKYPKILSDHHAIEFITDYLRLMVGGNLNPLEIENLMDGEIETHHQEGEV
PVHVIGKMGDALPAFGIVAAVMGVVHTMASVGIPPAELGKLIAAALVGTFLGILLAYGFVSPLASRLEQRLHESSKLLEC
IKVTLLANLNGYAPALAVEFGRKVLFSTERPSFIELEKHVKQSKAK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=59.5070422535211, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30745; Mature: 30745

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVTIGYLIVIVSVFGGFALAGGHLGSLFQPVELLMIAGAALGAFFVGNSGKAIKATFKA
CEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LPGVFQGARYTKVVYMELMTLLYEVLGKIRKEGLMSIEADVDDPAKSPLFTKYPKILSDH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHCCH
HAIEFITDYLRLMVGGNLNPLEIENLMDGEIETHHQEGEVPVHVIGKMGDALPAFGIVAA
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHCCCCCCCCHHHHHHHHCCHHHHHHHHHH
VMGVVHTMASVGIPPAELGKLIAAALVGTFLGILLAYGFVSPLASRLEQRLHESSKLLEC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTLLANLNGYAPALAVEFGRKVLFSTERPSFIELEKHVKQSKAK
HHHHHHHCCCCCCHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLVTIGYLIVIVSVFGGFALAGGHLGSLFQPVELLMIAGAALGAFFVGNSGKAIKATFKA
CEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LPGVFQGARYTKVVYMELMTLLYEVLGKIRKEGLMSIEADVDDPAKSPLFTKYPKILSDH
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHCCH
HAIEFITDYLRLMVGGNLNPLEIENLMDGEIETHHQEGEVPVHVIGKMGDALPAFGIVAA
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHCCCCCCCCHHHHHHHHCCHHHHHHHHHH
VMGVVHTMASVGIPPAELGKLIAAALVGTFLGILLAYGFVSPLASRLEQRLHESSKLLEC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKVTLLANLNGYAPALAVEFGRKVLFSTERPSFIELEKHVKQSKAK
HHHHHHHCCCCCCHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]