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The map label for this gene is ccmB [H]

Identifier: 114330093

GI number: 114330093

Start: 62027

End: 62710

Strand: Reverse

Name: ccmB [H]

Synonym: Neut_0062

Alternate gene names: 114330093

Gene position: 62710-62027 (Counterclockwise)

Preceding gene: 114330094

Following gene: 114330092

Centisome position: 2.36

GC content: 57.6

Gene sequence:

>684_bases
ATGAGCGACACCATTGGCTTATCCGTACTTCGCGGGGTAATACATCGAGATTTAAGGCTCGCCATGCGACGCAAGTCCGA
TGTGCTAACACCGCTTTTTTTCTTTGCCATCGTGGTCAGCCTGTTTCCGTTGGGCATTGGTTCTGAGCGCGACACGTTGC
GACAGATCGCTCCAGGCATTTTGTGGGTGGCGGCACTGCTGGCGTCTATGTTGTCGCTTGACCGGCTGTTTGAACAGGAT
TACGCCGACGGCACCTTGGAGCAAATGGCCCTTTCTCCCGCTCCGCTGGGGATGCTGGTGCTGGGCAAGGTGGTCGCGTA
TTGGCTATTGACGGGTTTGCCCTTGACCTTGCTGGCTCCGCTGCTGGCCTTGCAATTCGACTTGGCAACCCCTTCCTTAC
TGGTGCTGGCTGCGTCGCTGGCCATTGGTACCCCTGTACTTAGCTTTATTGGCGCGATCGGAGCGAGTTTGACCCTGGGC
CTGCGAGGCGGCAGCGTCCTTGTCGCCTTGCTTGTACTTCCGCTTTATGTGCCGGTCTTGATCTTTGGCGCGGGTTCCGT
AGACGCTGCCGCTGTCGGTCTGGGAGCTACGGCGCATCTGTCGTTGCTCGGCGCCGTGCTGGTTTTAACGGCTTTTTTTG
CACCGTGGGCCACAACCGTGGCATTACGGATTGCGTTGGAATAA

Upstream 100 bases:

>100_bases
GGCTGATTGACCAGCATCTGAGCAATGGCGGGATCGCAGTTTTGACGACGCATCAGGATTTGACCTTGACAGGCACGACG
CACGTTATACGGGTAGGCAT

Downstream 100 bases:

>100_bases
TGAGTAAATGAATGATTAATTGGTTTAAGTATTCATCGCCCAAAATGTTTTACCCCCTGGCCGGCAAGCTGATTCCATGG
TTTGCCGTCGCCGCCGCGAT

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSDTIGLSVLRGVIHRDLRLAMRRKSDVLTPLFFFAIVVSLFPLGIGSERDTLRQIAPGILWVAALLASMLSLDRLFEQD
YADGTLEQMALSPAPLGMLVLGKVVAYWLLTGLPLTLLAPLLALQFDLATPSLLVLAASLAIGTPVLSFIGAIGASLTLG
LRGGSVLVALLVLPLYVPVLIFGAGSVDAAAVGLGATAHLSLLGAVLVLTAFFAPWATTVALRIALE

Sequences:

>Translated_227_residues
MSDTIGLSVLRGVIHRDLRLAMRRKSDVLTPLFFFAIVVSLFPLGIGSERDTLRQIAPGILWVAALLASMLSLDRLFEQD
YADGTLEQMALSPAPLGMLVLGKVVAYWLLTGLPLTLLAPLLALQFDLATPSLLVLAASLAIGTPVLSFIGAIGASLTLG
LRGGSVLVALLVLPLYVPVLIFGAGSVDAAAVGLGATAHLSLLGAVLVLTAFFAPWATTVALRIALE
>Mature_226_residues
SDTIGLSVLRGVIHRDLRLAMRRKSDVLTPLFFFAIVVSLFPLGIGSERDTLRQIAPGILWVAALLASMLSLDRLFEQDY
ADGTLEQMALSPAPLGMLVLGKVVAYWLLTGLPLTLLAPLLALQFDLATPSLLVLAASLAIGTPVLSFIGAIGASLTLGL
RGGSVLVALLVLPLYVPVLIFGAGSVDAAAVGLGATAHLSLLGAVLVLTAFFAPWATTVALRIALE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=211, Percent_Identity=49.7630331753554, Blast_Score=158, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23693; Mature: 23562

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTIGLSVLRGVIHRDLRLAMRRKSDVLTPLFFFAIVVSLFPLGIGSERDTLRQIAPGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LWVAALLASMLSLDRLFEQDYADGTLEQMALSPAPLGMLVLGKVVAYWLLTGLPLTLLAP
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
LLALQFDLATPSLLVLAASLAIGTPVLSFIGAIGASLTLGLRGGSVLVALLVLPLYVPVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHH
IFGAGSVDAAAVGLGATAHLSLLGAVLVLTAFFAPWATTVALRIALE
HHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDTIGLSVLRGVIHRDLRLAMRRKSDVLTPLFFFAIVVSLFPLGIGSERDTLRQIAPGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LWVAALLASMLSLDRLFEQDYADGTLEQMALSPAPLGMLVLGKVVAYWLLTGLPLTLLAP
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
LLALQFDLATPSLLVLAASLAIGTPVLSFIGAIGASLTLGLRGGSVLVALLVLPLYVPVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHH
IFGAGSVDAAAVGLGATAHLSLLGAVLVLTAFFAPWATTVALRIALE
HHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]