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The map label for this gene is ccmE [H]

Identifier: 114330091

GI number: 114330091

Start: 60656

End: 61102

Strand: Reverse

Name: ccmE [H]

Synonym: Neut_0060

Alternate gene names: 114330091

Gene position: 61102-60656 (Counterclockwise)

Preceding gene: 114330092

Following gene: 114330090

Centisome position: 2.3

GC content: 55.7

Gene sequence:

>447_bases
ATGAAAAATCGCCATAAGCGCCTCGCGCTCATTGCTGGCGGCTTGGCCGCGTTCGGCATTGCCACAGCGTTAGTGCTCAA
TGCTTTTCAGAGCAACCTTGTGTTTTTCTTCACACCTACGCAGGTGAGTGCGGGTGAAGCCCCCCAGGAGCGGACGTTTC
GTGTCGGAGGTATGGTGCAAACCGGCAGTGTGCAGCGCCAAAGTGATGGGCTCACGGTGAAGTTCGTTGTCACCGATACC
GCCAAAATGATACCGGTCAGTTATACGGGAATATTGCCCGACCTGTTTAGTGAAGGCAAAGGGGTGGTGGCTCAAGGCAA
GCTCGGGGCCGATGGATTGTTCCGGGCGGAAGAGGTGCTTGCCAAACACGATGAGAACTATATGCCCCCTGAAGTGCAGC
ATGCGCTGGATGAGGCCGCCAAGAACACGATTACTGCGAGGCCATAA

Upstream 100 bases:

>100_bases
TGGTCGTTCTGTGCGCCGAGTGGCTCCTGCTGCGCCAGCGCCGCCAAGCGGCTTTATCGCAAGTAAAGCGCCAGTTAATC
CTAAGGGAAGAGGAATCTCG

Downstream 100 bases:

>100_bases
CGCTCATGATTGCTGAACTCGGTCATTTTTCACTGATTCTGACGCTATTCGTGGCGCTTGCGCAGGGCTGTTTAGCCCTC
GCCGGCGCGGCGCGTGACAA

Product: CcmE/CycJ protein

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MKNRHKRLALIAGGLAAFGIATALVLNAFQSNLVFFFTPTQVSAGEAPQERTFRVGGMVQTGSVQRQSDGLTVKFVVTDT
AKMIPVSYTGILPDLFSEGKGVVAQGKLGADGLFRAEEVLAKHDENYMPPEVQHALDEAAKNTITARP

Sequences:

>Translated_148_residues
MKNRHKRLALIAGGLAAFGIATALVLNAFQSNLVFFFTPTQVSAGEAPQERTFRVGGMVQTGSVQRQSDGLTVKFVVTDT
AKMIPVSYTGILPDLFSEGKGVVAQGKLGADGLFRAEEVLAKHDENYMPPEVQHALDEAAKNTITARP
>Mature_148_residues
MKNRHKRLALIAGGLAAFGIATALVLNAFQSNLVFFFTPTQVSAGEAPQERTFRVGGMVQTGSVQRQSDGLTVKFVVTDT
AKMIPVSYTGILPDLFSEGKGVVAQGKLGADGLFRAEEVLAKHDENYMPPEVQHALDEAAKNTITARP

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=140, Percent_Identity=45.7142857142857, Blast_Score=124, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 15860; Mature: 15860

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRHKRLALIAGGLAAFGIATALVLNAFQSNLVFFFTPTQVSAGEAPQERTFRVGGMVQ
CCCCHHEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEECCEEE
TGSVQRQSDGLTVKFVVTDTAKMIPVSYTGILPDLFSEGKGVVAQGKLGADGLFRAEEVL
CCCCEECCCCCEEEEEEECCCEECEEEHHCCCHHHHHCCCCEEEECCCCCCCHHHHHHHH
AKHDENYMPPEVQHALDEAAKNTITARP
HHCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNRHKRLALIAGGLAAFGIATALVLNAFQSNLVFFFTPTQVSAGEAPQERTFRVGGMVQ
CCCCHHEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEECCEEE
TGSVQRQSDGLTVKFVVTDTAKMIPVSYTGILPDLFSEGKGVVAQGKLGADGLFRAEEVL
CCCCEECCCCCEEEEEEECCCEECEEEHHCCCHHHHHCCCCEEEECCCCCCCHHHHHHHH
AKHDENYMPPEVQHALDEAAKNTITARP
HHCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12426355 [H]