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The map label for this gene is intA [H]

Identifier: 113970026

GI number: 113970026

Start: 1999986

End: 2001221

Strand: Direct

Name: intA [H]

Synonym: Shewmr4_1686

Alternate gene names: 113970026

Gene position: 1999986-2001221 (Clockwise)

Preceding gene: 113970025

Following gene: 113970027

Centisome position: 42.5

GC content: 45.47

Gene sequence:

>1236_bases
ATGGGAAGGAGTACAAATAAGCTGACTGCAAAAGCGGTGCTCAATGCTAAAGCGGAAGCAAAGCCCTATAGATTGTCAGA
TGGTGGCAATCTCTATCTCTATGTGCGTACTGCAGGGAAAACTTGGGAATTTAGATACATACGTCCCTCCACCAGCAAAC
CCACCTATTTTGGTTTAGGCTCATATCCTGACGTATCCTTAGCTGAGGCGCGAGATAAAGCGCTAGAAGCGCGAAAAAAC
TTGGCCGAAGGCATCGACCCTCAATTACTTAAAGTTGAAAACAAATTAAAAGCGGCAACAGAGAACGCTCAAACTCTCAA
GCATATTGCGCAAATGTGGATGGACTCTAAGCAGGGAAGCATTAAGCCTAAAACCATCGAAGGCAATTGGCGTAAGCTTG
AGCTGTATGCCTTCCCTAAACTGGGGAGTATTGCGATTAGCAGACTCACGGCTCCCATAGCCATTGCCGCGCTAAAGCCC
CTAGAGCAGAAGGGGCATCTTGAAACGGTTAAGCGTACCGCTCAGTTGCTGAATGAAATCATGAACTTTTCAGTTAACTC
TGGTTACATTCATGCTAATCCGTTGTCAGGTATTCGAGAAGTTTTTAGAAAGAGCAAAGTAGAACATCTGAAAGCATTAA
AACCAGCAGAGCTAGCTGAGTTGCTGCAGACTATTGCAAACGCCAATTTATTGTTAACGACCCGGTGTTTGATTGAATGG
CAATTGCACACAATGACCAGGCCAAATGAAGCGGCCGGAGCCCGTTGGGAAGAAATCGATTTTGATGCCAAACTTTGGAC
TATTCCTGAATCACGCATGAAAATGAATCGTGAGCATATTATCCCGCTTACAGAGCATACCCTCGCGATACTCGAAACTG
TTAAGCCGATTAGTGAACAGAGCCAATTTGTCTTTCCATCATCTAAAGATCCTCAAAAGCACACAGATCCTGAAACCATT
AACAAAGCATTAGGGCGCATGGGATTAAAGGGAAGAACAACGGGTCATGGTTTACGCTCGCTTGCGAGCACTACCTTAAA
CGAGCAAGGCTTTGATGGTGATGTTATTGAGGCAGCGTTAGCCCATGTTGATAAAAACCAAATCCGCAGTGCCTATAATC
GCACGACCTACCTAGAGCGACGGACCAAGTTAATGGAGTGGTGGAGCAACCATATTGCCACTGCAGCAGTGGGCTCTTTG
TCAGTAACAGCTAGTTCAAGAAAATTAGGGGCATGA

Upstream 100 bases:

>100_bases
TCTTAATTTATTCAGTGATAAGTAATGCTTGATTTTCGAGTGAAAAATGATGCCAAAATCAAGCATTACTTTTGGGTTTA
ATTTGAGAGGGTAAAACGGT

Downstream 100 bases:

>100_bases
CCTATAAGGCCGAGTAGAGATTATCTCCCTGAGCCAAAAGATAGGGGACGTGATACACGAATCTAACCTGTTAAGTCCGA
CTCAGGGTTGTTACTCTTAC

Product: phage integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MGRSTNKLTAKAVLNAKAEAKPYRLSDGGNLYLYVRTAGKTWEFRYIRPSTSKPTYFGLGSYPDVSLAEARDKALEARKN
LAEGIDPQLLKVENKLKAATENAQTLKHIAQMWMDSKQGSIKPKTIEGNWRKLELYAFPKLGSIAISRLTAPIAIAALKP
LEQKGHLETVKRTAQLLNEIMNFSVNSGYIHANPLSGIREVFRKSKVEHLKALKPAELAELLQTIANANLLLTTRCLIEW
QLHTMTRPNEAAGARWEEIDFDAKLWTIPESRMKMNREHIIPLTEHTLAILETVKPISEQSQFVFPSSKDPQKHTDPETI
NKALGRMGLKGRTTGHGLRSLASTTLNEQGFDGDVIEAALAHVDKNQIRSAYNRTTYLERRTKLMEWWSNHIATAAVGSL
SVTASSRKLGA

Sequences:

>Translated_411_residues
MGRSTNKLTAKAVLNAKAEAKPYRLSDGGNLYLYVRTAGKTWEFRYIRPSTSKPTYFGLGSYPDVSLAEARDKALEARKN
LAEGIDPQLLKVENKLKAATENAQTLKHIAQMWMDSKQGSIKPKTIEGNWRKLELYAFPKLGSIAISRLTAPIAIAALKP
LEQKGHLETVKRTAQLLNEIMNFSVNSGYIHANPLSGIREVFRKSKVEHLKALKPAELAELLQTIANANLLLTTRCLIEW
QLHTMTRPNEAAGARWEEIDFDAKLWTIPESRMKMNREHIIPLTEHTLAILETVKPISEQSQFVFPSSKDPQKHTDPETI
NKALGRMGLKGRTTGHGLRSLASTTLNEQGFDGDVIEAALAHVDKNQIRSAYNRTTYLERRTKLMEWWSNHIATAAVGSL
SVTASSRKLGA
>Mature_410_residues
GRSTNKLTAKAVLNAKAEAKPYRLSDGGNLYLYVRTAGKTWEFRYIRPSTSKPTYFGLGSYPDVSLAEARDKALEARKNL
AEGIDPQLLKVENKLKAATENAQTLKHIAQMWMDSKQGSIKPKTIEGNWRKLELYAFPKLGSIAISRLTAPIAIAALKPL
EQKGHLETVKRTAQLLNEIMNFSVNSGYIHANPLSGIREVFRKSKVEHLKALKPAELAELLQTIANANLLLTTRCLIEWQ
LHTMTRPNEAAGARWEEIDFDAKLWTIPESRMKMNREHIIPLTEHTLAILETVKPISEQSQFVFPSSKDPQKHTDPETIN
KALGRMGLKGRTTGHGLRSLASTTLNEQGFDGDVIEAALAHVDKNQIRSAYNRTTYLERRTKLMEWWSNHIATAAVGSLS
VTASSRKLGA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=408, Percent_Identity=43.3823529411765, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1788690, Length=389, Percent_Identity=29.305912596401, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI145693166, Length=401, Percent_Identity=30.9226932668329, Blast_Score=159, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45918; Mature: 45787

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRSTNKLTAKAVLNAKAEAKPYRLSDGGNLYLYVRTAGKTWEFRYIRPSTSKPTYFGLG
CCCCCCHHHHHHHHCCCCCCCCEEECCCCEEEEEEEECCCEEEEEEECCCCCCCCEEECC
SYPDVSLAEARDKALEARKNLAEGIDPQLLKVENKLKAATENAQTLKHIAQMWMDSKQGS
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IKPKTIEGNWRKLELYAFPKLGSIAISRLTAPIAIAALKPLEQKGHLETVKRTAQLLNEI
CCCEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHH
MNFSVNSGYIHANPLSGIREVFRKSKVEHLKALKPAELAELLQTIANANLLLTTRCLIEW
HCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEHEEE
QLHTMTRPNEAAGARWEEIDFDAKLWTIPESRMKMNREHIIPLTEHTLAILETVKPISEQ
EHHHCCCCCHHHCCCCHHCCCCCEEEECCHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCC
SQFVFPSSKDPQKHTDPETINKALGRMGLKGRTTGHGLRSLASTTLNEQGFDGDVIEAAL
CCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
AHVDKNQIRSAYNRTTYLERRTKLMEWWSNHIATAAVGSLSVTASSRKLGA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
>Mature Secondary Structure 
GRSTNKLTAKAVLNAKAEAKPYRLSDGGNLYLYVRTAGKTWEFRYIRPSTSKPTYFGLG
CCCCCHHHHHHHHCCCCCCCCEEECCCCEEEEEEEECCCEEEEEEECCCCCCCCEEECC
SYPDVSLAEARDKALEARKNLAEGIDPQLLKVENKLKAATENAQTLKHIAQMWMDSKQGS
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IKPKTIEGNWRKLELYAFPKLGSIAISRLTAPIAIAALKPLEQKGHLETVKRTAQLLNEI
CCCEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHH
MNFSVNSGYIHANPLSGIREVFRKSKVEHLKALKPAELAELLQTIANANLLLTTRCLIEW
HCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEHEEE
QLHTMTRPNEAAGARWEEIDFDAKLWTIPESRMKMNREHIIPLTEHTLAILETVKPISEQ
EHHHCCCCCHHHCCCCHHCCCCCEEEECCHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCC
SQFVFPSSKDPQKHTDPETINKALGRMGLKGRTTGHGLRSLASTTLNEQGFDGDVIEAAL
CCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
AHVDKNQIRSAYNRTTYLERRTKLMEWWSNHIATAAVGSLSVTASSRKLGA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]