Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 113970025

GI number: 113970025

Start: 1997345

End: 1999339

Strand: Direct

Name: hlyB [H]

Synonym: Shewmr4_1685

Alternate gene names: 113970025

Gene position: 1997345-1999339 (Clockwise)

Preceding gene: 113970024

Following gene: 113970026

Centisome position: 42.44

GC content: 48.22

Gene sequence:

>1995_bases
ATGAAATGGCAATGGATTGGCAACCTCAGCTTGAAACAAAAATTACTCATGGTTGTATTGCCGCCCTTATTTGCATGTTT
TTTATATGGTGCTTTGTTTCTCATTGAAAAATATGAGTATCGTCAAGAGCTTAAGCTTATCGTCCAATTGAGTGAATTGG
CGGTCACCAACAGTAATCTGGTGCATGAGCTACAAAAAGAGCGTGGCATGAGCGCAGGCTTTATTGGCTCAGCGGGTAAA
GCCTTTGCAGGCAAAATCCCAAGTCAAAGACAACTGACGGATAGCCAGTTAAAACAATTCCAAGATTTCATTTCAAACAA
TGCGTTACCCGAAGTGTTTGCGCCTAAATTACGGGAGATCAACACTCAGCTTGGTCGCCTTTCTGGGATCCGTTCGCAAA
TCGACAGTTTATCCATCAGTGTGGCCGATGAAGTGGCCTATTACACCGATCTCAATAAACAGTTATTGGCCATCGTCGAT
GAAACGGCAAAGGCTGGCGCCAACCAAGAAATTGCCATTAAGGCCGCGGCATTCAGTGCCTATCTGCAAATGAAGGAACG
GGCGGGGATTGAGCGTGCGGTCTTAAGTTCAACCTTCGGCCAAGCAGGTTTCAAACCTAAGGTATATGCCAAGTTTATAA
CCTTAGTCTCTGAGCAAAATACTTATCTGGAGCGCTTCTTGGCACTTGCCACGCCCAATCTCGTCGAGGGTATTCGTCAG
CTGCAAAATGGTAACGAAGTCAGTGAAGTTGAGGCGCTGAGACAAATAGCAATCGACCAAGATAATCAAAAAATTCAGCA
ACAAAACCCGGAGGATTGGTTTGCGAAATCCACGGCACGTATCGACCGTTTACGGGATTTTGAGCAAGAGGTTTCTACCG
ATCTGGTTAAGACCACCACAGACCGACTCTATACCGCCAACGAGCATATGTTCTTCGTGCTCGTGACATTAACCGTGGTG
TTAGTGTTAGTGCTGCTGTTGAGTTTATCGGTTATCCGTTACCTACACGACAGTGTGCACCATGTGTATTCGACGGTGAC
AAAGGCCAGGAAACATTATGATCTCAGTGTGCGTTTAACCCAAAATAGCTCGGATGAATTTGGGGAGTTAGCCATTGCAT
TCAACGACATGATGAATGATTTCGAGAGTGTGATCCTGCAAGTGCGTGCCAGTGCCAGCAAGTTACAACAAGCGGTAGAG
CAAATGGATGTGTGTACCCACGCAATGGAGCAAGATGTGATGGCAGGGCACAGTGAGGCCGAACAAGTGGCCTCGGCAAT
GACGGAGATGAGTGCGACGGTGGCAGAAATCGCCAGTAACGCCGTTAATGCATCGGAAGCCTCCACCGCGGCGAATCATG
AGGCAAAAGCGGGTAATATCGAAGTGGGTCGTACCAGTGCCGCCATTAAGGCTTTAGCCGATGATATTGATGGCGCCTCT
AAGGCCATTAATGAACTCGACCGTGAAATCCACGGTATTGTGGTGGTACTCGATGTGATAAGCGGCATTGCCGAACAAAC
GAATCTACTTGCACTTAATGCGGCGATTGAAGCGGCAAGGGCAGGCGAGATGGGACGGGGCTTTGCCGTCGTGGCCGATG
AAGTGAGAAGTCTTGCGCAGCGCTCACAAACCTCGACCTCCGATATTAAGAACATGACGGATAGACTGAAATCGGGCGCC
AGCATTGCCGTTAAAGCCATGGAACGCGGACTCGCACAGGCCAATAACAGCGTGCACGAAGCCGAGCAGGCGGGGATTGA
GCTTAAACGTATCGTCGAGCAAGTGGATATTATCGACCGCATGAATGAGCAAATTGCCACGGCAACCCATGAACAGTCTG
CCGTGTCTGAGGATGTGAATCGCAATGCATTGAAGATCAGTGAAATTTATCTCAATACCCAGAGGATTTCGGATGAATTA
CGGGAATTGACCAAGGCACTGACCTACGATGCGGCGCTAATGTCCAAGGAAGTGAACAAGTTCAACGTCAATTAA

Upstream 100 bases:

>100_bases
AGTAATAGCTAAATTAGGTAAAAATGGTCGTTCTCGCGTAAATCCTATGCTATACCTATTTTGTCTTATCTCTTAACCTC
GCTTTAATAAGGAAATCACT

Downstream 100 bases:

>100_bases
TGGCGAAAGTCGGACATAAATCTCAATTTATCAGGCGGTTTGTTTAGCAATTGCGCAACCGCCTGAAATCAACTCTTTTT
TACTTGACCACCCACAGGCT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MKWQWIGNLSLKQKLLMVVLPPLFACFLYGALFLIEKYEYRQELKLIVQLSELAVTNSNLVHELQKERGMSAGFIGSAGK
AFAGKIPSQRQLTDSQLKQFQDFISNNALPEVFAPKLREINTQLGRLSGIRSQIDSLSISVADEVAYYTDLNKQLLAIVD
ETAKAGANQEIAIKAAAFSAYLQMKERAGIERAVLSSTFGQAGFKPKVYAKFITLVSEQNTYLERFLALATPNLVEGIRQ
LQNGNEVSEVEALRQIAIDQDNQKIQQQNPEDWFAKSTARIDRLRDFEQEVSTDLVKTTTDRLYTANEHMFFVLVTLTVV
LVLVLLLSLSVIRYLHDSVHHVYSTVTKARKHYDLSVRLTQNSSDEFGELAIAFNDMMNDFESVILQVRASASKLQQAVE
QMDVCTHAMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVNASEASTAANHEAKAGNIEVGRTSAAIKALADDIDGAS
KAINELDREIHGIVVVLDVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRSQTSTSDIKNMTDRLKSGA
SIAVKAMERGLAQANNSVHEAEQAGIELKRIVEQVDIIDRMNEQIATATHEQSAVSEDVNRNALKISEIYLNTQRISDEL
RELTKALTYDAALMSKEVNKFNVN

Sequences:

>Translated_664_residues
MKWQWIGNLSLKQKLLMVVLPPLFACFLYGALFLIEKYEYRQELKLIVQLSELAVTNSNLVHELQKERGMSAGFIGSAGK
AFAGKIPSQRQLTDSQLKQFQDFISNNALPEVFAPKLREINTQLGRLSGIRSQIDSLSISVADEVAYYTDLNKQLLAIVD
ETAKAGANQEIAIKAAAFSAYLQMKERAGIERAVLSSTFGQAGFKPKVYAKFITLVSEQNTYLERFLALATPNLVEGIRQ
LQNGNEVSEVEALRQIAIDQDNQKIQQQNPEDWFAKSTARIDRLRDFEQEVSTDLVKTTTDRLYTANEHMFFVLVTLTVV
LVLVLLLSLSVIRYLHDSVHHVYSTVTKARKHYDLSVRLTQNSSDEFGELAIAFNDMMNDFESVILQVRASASKLQQAVE
QMDVCTHAMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVNASEASTAANHEAKAGNIEVGRTSAAIKALADDIDGAS
KAINELDREIHGIVVVLDVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRSQTSTSDIKNMTDRLKSGA
SIAVKAMERGLAQANNSVHEAEQAGIELKRIVEQVDIIDRMNEQIATATHEQSAVSEDVNRNALKISEIYLNTQRISDEL
RELTKALTYDAALMSKEVNKFNVN
>Mature_664_residues
MKWQWIGNLSLKQKLLMVVLPPLFACFLYGALFLIEKYEYRQELKLIVQLSELAVTNSNLVHELQKERGMSAGFIGSAGK
AFAGKIPSQRQLTDSQLKQFQDFISNNALPEVFAPKLREINTQLGRLSGIRSQIDSLSISVADEVAYYTDLNKQLLAIVD
ETAKAGANQEIAIKAAAFSAYLQMKERAGIERAVLSSTFGQAGFKPKVYAKFITLVSEQNTYLERFLALATPNLVEGIRQ
LQNGNEVSEVEALRQIAIDQDNQKIQQQNPEDWFAKSTARIDRLRDFEQEVSTDLVKTTTDRLYTANEHMFFVLVTLTVV
LVLVLLLSLSVIRYLHDSVHHVYSTVTKARKHYDLSVRLTQNSSDEFGELAIAFNDMMNDFESVILQVRASASKLQQAVE
QMDVCTHAMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVNASEASTAANHEAKAGNIEVGRTSAAIKALADDIDGAS
KAINELDREIHGIVVVLDVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRSQTSTSDIKNMTDRLKSGA
SIAVKAMERGLAQANNSVHEAEQAGIELKRIVEQVDIIDRMNEQIATATHEQSAVSEDVNRNALKISEIYLNTQRISDEL
RELTKALTYDAALMSKEVNKFNVN

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=361, Percent_Identity=26.8698060941828, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1788195, Length=282, Percent_Identity=31.2056737588652, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787690, Length=361, Percent_Identity=28.5318559556787, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1789453, Length=344, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1788194, Length=242, Percent_Identity=33.0578512396694, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73238; Mature: 73238

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50885 HAMP ; PS50906 NIT ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]