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The map label for this gene is apr [H]

Identifier: 113969937

GI number: 113969937

Start: 1888747

End: 1892535

Strand: Direct

Name: apr [H]

Synonym: Shewmr4_1596

Alternate gene names: 113969937

Gene position: 1888747-1892535 (Clockwise)

Preceding gene: 113969936

Following gene: 113969940

Centisome position: 40.13

GC content: 51.99

Gene sequence:

>3789_bases
ATGAAACAACTTTTTAAGCGCAGCCGTATCGCTGTGACTTGCTTGATGGCGATGGGTTTTACCACCAGTTATACCACGTT
GGCAGATGACAATGTGGCGCTGATGGCGGCGCAGTCTGGTGCCGTACAATTTACCTTGATCACAGGTGAGGTGGTAACGG
CCGTGGTGCGCGCCGATGGTTCCCTCGGTGGGATCCGTCTACTCGGTGAAAATGGTGCCGAGGTGATCACGAGTATTTTT
CAGAATCAGAATGGTCAATATCTGATTACGCCAAAGGCGCAAAAATGGGTCGAGTCTCAAACCGTTGACATCGAGCTTTT
TAACATCTCTAAGTTACATGCAGCCGGTTATGATGATGCCTCGACCGATAAACTGCCTGTCATTATCGAATACCGCGACG
GTACCCTCGCGGGCTCTGCTGTGCCGAATTTAATTGAAGGAGCGACCCTAACCGATGAGATTGAACTTATCGATAGTGCC
GCCTTTGGGATCAGCAAGCAACAGGCGGCTAAAGTATGGGAAACCCTAAGTACCGATGATGCGGTTAAGTCGGTGTGGTT
GGATGCGGTAGTGCATGCTCATAAAGATCCGACCAATGGGGTTAATGCGCTAGCGAACTTAACCCCAACCGTGCCATTAA
CGGGGGCATATGGCAATTTAGCCAAACAATTCAATGGTCAGGGGGTCACGGTTGCCGTGCTCGATACTGGCTACGATGTG
CAGCATGGCGATTTGGCGGGACAAGTTGTGCAAAGCAAAGATTTTACCTACTCTAGTAATGGCGTTGATGATCTTAACGG
CCATGGCACACATACTGCGGCCACCATCGCGGGAACGGGAGTGGAATCGAATAGCCTCTGGGCCGGTATGGCGCCGGGAG
CTAAGCTGCTGGTGGGCAAGGTTCTGACGAACTCAGGCGCAGGCTCGACGAGTGGGATCCTCAGTGGTATGCAATGGGCC
GTGAGTCAGGGCGCCGATGTGGTCAGTATGTCGTTAGGCGGCAGTGGCACCAGTTGTACTGGACCGCTTGTCGATATGGT
CGAAGCCTTGAGTGATAAGGCGCTGTTCGTCGTTTCGGCGGGCAATAGTTTTACCCGTGAGACAGTGGGGCTCCCTGGAT
GTGCCCCTAGCGCGTTAACCGTTGGAGCCGTTGACCGAGACAATAACACTGCTTCTTTCTCATCCCGTGGACCATCACCA
GATGGCCATTCCGCTAAGCCAGATATAGCATCTCAAGGTGTGGATGTCGTTTCGGCGGCATCAGGGGGATTTGGCGCGAC
GGCATATCGCGCACTGTCGGGAACGTCAATGTCAGCGCCCCATGTGTCTGGCGGCGCGGCGATCGTGATGCAAGCCAGAC
CCGACCTTAGCCCTCGCCAAATTAAAGAGGTGCTGACCTCATCCGTAGTGCCAACCGATGCCCATGTGCTTGAGCAAGGC
GCGGGGCCAATGGATGTCAATCGCGCCATATCGCAAAGCATTATCGCGCCGCCCAATATGGAGCTTGGTTCCTTTGCCTA
TGGTCAGGATATTGGCGTAACAGAAAAAACCATCAGCTTGCGCAATTTATCCGATAAGGATATTAGCCTGAAGCTGAAAA
TGAGTTTGATCGGTGAAGATGGCAAGACGCGCATGCCAGCAACTTTGGCAGGACTGGGGACCAACAGCATTAACGTGCCA
GCCAATGGCAGTGCTGAAATCCCTGTGTGGATTGACTCGAGTGTGGCGCTGCGCAGTGGAGCCTATGGCACTATCACCGG
GCGGATTGAAGGCACTGCTACTGGGAAATCTGATGAACGCGTGACAGTGCCGATTTCATTCTGGATAGAACCGCCTCAAG
TTAACTTGAGCTTAAGTGTTACCGACATGCGCGGCAAACCTGCATCCTCTCCCTCGAGAGTGTACTTGATGAATGAGGAA
GATGATTGGGGACAAGCCGTTACGCTTAGGAATGGTCAAGCAAGTCTGTCAGTCCCTGAGGGCAATTACACTATCGTTGC
GAACGTAATGACCTACGATAATGACTCTACAACTTCAGGTTTAGTGGAGTCAGCCACCCAAATGGCGGTGCTGAATCGTA
AACTGAGCCAAGATACCCAGATTGAGTTCGACGCTCGAAACGCCGAGAAACTCGAGTTCAAAGCGAGCCAACCTTTGGCG
CCGCAAGGATATGCGTTTGGCTTCACCTATGCGCTGGATGATAACAAAGTGGCGAAATTAGCCGCGATGGAACTGGCGCC
TGATTACGTGAAAGACATCTACACTTGGTCGCAGGGACATGATGATAGATTCCGCTCGTTTGTGACGACCCGTGCCTTTG
CCCCCGAAACAGTGCTCACCATGCAAAATGGCGAAGTGCTCGATTATAACAAGCAGGGGTTAGCCTTATCATTTGATGGC
GAAGGTCGCGCTGAAGTTGTGCCAGTCGGAGACGCTGGCTACAGTACCGACTGGACTCAGTTTGACTTAACGGGTCGTAT
TGCACTTATTGGTAACCCTTATTATCTTACGTCTTATATGGCGGCGAATGCCCTTAAATCCGGCGCAATTGGGGTCATCT
TCTATCGTCCGGGTCTACATGGTCGCTATAAGGGCACAATTTCTGGCACGCCACGGATCCCCGTCGTCGGGATTAGTTCG
GAGCAGGGGGAAGCCCTATTGGCGCAGATTGAAGCGGGGAACAATATCGTCAGTTGGTCTGGCACCGCTGCAGAGCGGAC
ACCCTATGCTTATTCCATTAACCATATCACCGATGGACGTATCAGTGGCGGACAGGTTGTACTTCAAGAGCAGAAAATGC
AGCGCATTCGTGCCAGCTATCACTCGCAAAATGATCAGCGTCCAATTTGGACCGATATGATGGCCATGACCAACAGCACT
GGGGAGTTTTACTCCACTGGCAGTTCGCAGATGGTCATGACGCCCGTGGTGCGCGATGAATACTACACTGCAACCAGCAA
AAACATGTGGACTAACATTGTGATGCCCGGTATTCAGTTCTCGACGGACGGCGGCTATTTTGATGGTCCAAGAATGATGA
CCGAAGGCACGGTTGAGACCACCTCTTGGCTAAAAGGCCCCAAGGCGGGGAGTTTGCTCAGCAATGGCGGCGCCATTGCA
AATCGCGATACCAACACCATCGACTTAAGCATTGTTCGCTTTGGCGATGCAGCAGGACACGATGGTATCGGTGGCTATAA
TTCTCAGTCGCTTTATGGACTAAGAGTCAATGGGCAGAACACCTACTTAGACAGTGGACTGTTTACCCTCCCCGATACCA
ATGCACAAGTTGAGTTAGAAGTGCGCTCCTACGCCCGTGGTGTGGGCAATAGCTCACCTGTGAAGGACAATCTTGGCTCC
TTCTATCAAGGGATTTATCAATTCAGCACAGACTCGAGTAAACAGGGTCGCCAAGCGGTGCTCACTCCTAAGCTCGACAT
TCCGGTTGCGATAGATAATACCTTGGCTGCAGGCGTACCTGTCGAAGTGAAACTTTCTGCTGTGATGGATGGCGCGGCGC
AGGTGGATTTATCCGATGTCACGCTGCAATACGGCTATGGTCAGGAATGTTCGTTAGCCGAGATTCCGGTATCGATTTAC
TGCCCAGTAACATCGAAATTTGCCGAAAGCGCATGGAAAACCGCAGAAGTAAAATGGGTTAACGGTGAGTGGGTTGCCAC
AATCCCGAACGATTCCACCGCCGGCAATTTTGTTCACTTACGTGTGCAGATGAGTGATGGCAATAGCGAAGCGAAACAAA
CCATGATGCGGGTGTATATGCTGAAGTAA

Upstream 100 bases:

>100_bases
AAACGCCATCTTGCTGCTTTGGAAGCGAGTCTTCCAACATAAAAAACGTTGCTTGAAGTTGATTTGGGCAATCTCAAGGT
GATTTTTCAAGGAATATGAA

Downstream 100 bases:

>100_bases
TCTACTGTTATTGGTCGATAAAACCGCGACTAGCCACGCTAGTGGCGGTTTTTATTTGCCAGTTATAAAGGGAGGAGGAG
CATGAGCAGCACGAGACTTG

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1262; Mature: 1262

Protein sequence:

>1262_residues
MKQLFKRSRIAVTCLMAMGFTTSYTTLADDNVALMAAQSGAVQFTLITGEVVTAVVRADGSLGGIRLLGENGAEVITSIF
QNQNGQYLITPKAQKWVESQTVDIELFNISKLHAAGYDDASTDKLPVIIEYRDGTLAGSAVPNLIEGATLTDEIELIDSA
AFGISKQQAAKVWETLSTDDAVKSVWLDAVVHAHKDPTNGVNALANLTPTVPLTGAYGNLAKQFNGQGVTVAVLDTGYDV
QHGDLAGQVVQSKDFTYSSNGVDDLNGHGTHTAATIAGTGVESNSLWAGMAPGAKLLVGKVLTNSGAGSTSGILSGMQWA
VSQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSAGNSFTRETVGLPGCAPSALTVGAVDRDNNTASFSSRGPSP
DGHSAKPDIASQGVDVVSAASGGFGATAYRALSGTSMSAPHVSGGAAIVMQARPDLSPRQIKEVLTSSVVPTDAHVLEQG
AGPMDVNRAISQSIIAPPNMELGSFAYGQDIGVTEKTISLRNLSDKDISLKLKMSLIGEDGKTRMPATLAGLGTNSINVP
ANGSAEIPVWIDSSVALRSGAYGTITGRIEGTATGKSDERVTVPISFWIEPPQVNLSLSVTDMRGKPASSPSRVYLMNEE
DDWGQAVTLRNGQASLSVPEGNYTIVANVMTYDNDSTTSGLVESATQMAVLNRKLSQDTQIEFDARNAEKLEFKASQPLA
PQGYAFGFTYALDDNKVAKLAAMELAPDYVKDIYTWSQGHDDRFRSFVTTRAFAPETVLTMQNGEVLDYNKQGLALSFDG
EGRAEVVPVGDAGYSTDWTQFDLTGRIALIGNPYYLTSYMAANALKSGAIGVIFYRPGLHGRYKGTISGTPRIPVVGISS
EQGEALLAQIEAGNNIVSWSGTAAERTPYAYSINHITDGRISGGQVVLQEQKMQRIRASYHSQNDQRPIWTDMMAMTNST
GEFYSTGSSQMVMTPVVRDEYYTATSKNMWTNIVMPGIQFSTDGGYFDGPRMMTEGTVETTSWLKGPKAGSLLSNGGAIA
NRDTNTIDLSIVRFGDAAGHDGIGGYNSQSLYGLRVNGQNTYLDSGLFTLPDTNAQVELEVRSYARGVGNSSPVKDNLGS
FYQGIYQFSTDSSKQGRQAVLTPKLDIPVAIDNTLAAGVPVEVKLSAVMDGAAQVDLSDVTLQYGYGQECSLAEIPVSIY
CPVTSKFAESAWKTAEVKWVNGEWVATIPNDSTAGNFVHLRVQMSDGNSEAKQTMMRVYMLK

Sequences:

>Translated_1262_residues
MKQLFKRSRIAVTCLMAMGFTTSYTTLADDNVALMAAQSGAVQFTLITGEVVTAVVRADGSLGGIRLLGENGAEVITSIF
QNQNGQYLITPKAQKWVESQTVDIELFNISKLHAAGYDDASTDKLPVIIEYRDGTLAGSAVPNLIEGATLTDEIELIDSA
AFGISKQQAAKVWETLSTDDAVKSVWLDAVVHAHKDPTNGVNALANLTPTVPLTGAYGNLAKQFNGQGVTVAVLDTGYDV
QHGDLAGQVVQSKDFTYSSNGVDDLNGHGTHTAATIAGTGVESNSLWAGMAPGAKLLVGKVLTNSGAGSTSGILSGMQWA
VSQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSAGNSFTRETVGLPGCAPSALTVGAVDRDNNTASFSSRGPSP
DGHSAKPDIASQGVDVVSAASGGFGATAYRALSGTSMSAPHVSGGAAIVMQARPDLSPRQIKEVLTSSVVPTDAHVLEQG
AGPMDVNRAISQSIIAPPNMELGSFAYGQDIGVTEKTISLRNLSDKDISLKLKMSLIGEDGKTRMPATLAGLGTNSINVP
ANGSAEIPVWIDSSVALRSGAYGTITGRIEGTATGKSDERVTVPISFWIEPPQVNLSLSVTDMRGKPASSPSRVYLMNEE
DDWGQAVTLRNGQASLSVPEGNYTIVANVMTYDNDSTTSGLVESATQMAVLNRKLSQDTQIEFDARNAEKLEFKASQPLA
PQGYAFGFTYALDDNKVAKLAAMELAPDYVKDIYTWSQGHDDRFRSFVTTRAFAPETVLTMQNGEVLDYNKQGLALSFDG
EGRAEVVPVGDAGYSTDWTQFDLTGRIALIGNPYYLTSYMAANALKSGAIGVIFYRPGLHGRYKGTISGTPRIPVVGISS
EQGEALLAQIEAGNNIVSWSGTAAERTPYAYSINHITDGRISGGQVVLQEQKMQRIRASYHSQNDQRPIWTDMMAMTNST
GEFYSTGSSQMVMTPVVRDEYYTATSKNMWTNIVMPGIQFSTDGGYFDGPRMMTEGTVETTSWLKGPKAGSLLSNGGAIA
NRDTNTIDLSIVRFGDAAGHDGIGGYNSQSLYGLRVNGQNTYLDSGLFTLPDTNAQVELEVRSYARGVGNSSPVKDNLGS
FYQGIYQFSTDSSKQGRQAVLTPKLDIPVAIDNTLAAGVPVEVKLSAVMDGAAQVDLSDVTLQYGYGQECSLAEIPVSIY
CPVTSKFAESAWKTAEVKWVNGEWVATIPNDSTAGNFVHLRVQMSDGNSEAKQTMMRVYMLK
>Mature_1262_residues
MKQLFKRSRIAVTCLMAMGFTTSYTTLADDNVALMAAQSGAVQFTLITGEVVTAVVRADGSLGGIRLLGENGAEVITSIF
QNQNGQYLITPKAQKWVESQTVDIELFNISKLHAAGYDDASTDKLPVIIEYRDGTLAGSAVPNLIEGATLTDEIELIDSA
AFGISKQQAAKVWETLSTDDAVKSVWLDAVVHAHKDPTNGVNALANLTPTVPLTGAYGNLAKQFNGQGVTVAVLDTGYDV
QHGDLAGQVVQSKDFTYSSNGVDDLNGHGTHTAATIAGTGVESNSLWAGMAPGAKLLVGKVLTNSGAGSTSGILSGMQWA
VSQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSAGNSFTRETVGLPGCAPSALTVGAVDRDNNTASFSSRGPSP
DGHSAKPDIASQGVDVVSAASGGFGATAYRALSGTSMSAPHVSGGAAIVMQARPDLSPRQIKEVLTSSVVPTDAHVLEQG
AGPMDVNRAISQSIIAPPNMELGSFAYGQDIGVTEKTISLRNLSDKDISLKLKMSLIGEDGKTRMPATLAGLGTNSINVP
ANGSAEIPVWIDSSVALRSGAYGTITGRIEGTATGKSDERVTVPISFWIEPPQVNLSLSVTDMRGKPASSPSRVYLMNEE
DDWGQAVTLRNGQASLSVPEGNYTIVANVMTYDNDSTTSGLVESATQMAVLNRKLSQDTQIEFDARNAEKLEFKASQPLA
PQGYAFGFTYALDDNKVAKLAAMELAPDYVKDIYTWSQGHDDRFRSFVTTRAFAPETVLTMQNGEVLDYNKQGLALSFDG
EGRAEVVPVGDAGYSTDWTQFDLTGRIALIGNPYYLTSYMAANALKSGAIGVIFYRPGLHGRYKGTISGTPRIPVVGISS
EQGEALLAQIEAGNNIVSWSGTAAERTPYAYSINHITDGRISGGQVVLQEQKMQRIRASYHSQNDQRPIWTDMMAMTNST
GEFYSTGSSQMVMTPVVRDEYYTATSKNMWTNIVMPGIQFSTDGGYFDGPRMMTEGTVETTSWLKGPKAGSLLSNGGAIA
NRDTNTIDLSIVRFGDAAGHDGIGGYNSQSLYGLRVNGQNTYLDSGLFTLPDTNAQVELEVRSYARGVGNSSPVKDNLGS
FYQGIYQFSTDSSKQGRQAVLTPKLDIPVAIDNTLAAGVPVEVKLSAVMDGAAQVDLSDVTLQYGYGQECSLAEIPVSIY
CPVTSKFAESAWKTAEVKWVNGEWVATIPNDSTAGNFVHLRVQMSDGNSEAKQTMMRVYMLK

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=304, Percent_Identity=32.5657894736842, Blast_Score=105, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319893, Length=260, Percent_Identity=33.0769230769231, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320775, Length=266, Percent_Identity=30.8270676691729, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324576, Length=264, Percent_Identity=29.9242424242424, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45550681, Length=292, Percent_Identity=30.4794520547945, Blast_Score=102, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 133788; Mature: 133788

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLFKRSRIAVTCLMAMGFTTSYTTLADDNVALMAAQSGAVQFTLITGEVVTAVVRADG
CHHHHHHHHHHEEEHHHHCCCCCEEEECCCCEEEEEECCCCEEEEEEEHHHHEEEEECCC
SLGGIRLLGENGAEVITSIFQNQNGQYLITPKAQKWVESQTVDIELFNISKLHAAGYDDA
CCCCEEEECCCCHHHHHHHHHCCCCCEEECCCHHHHHCCCEEEEEEEEEEEEEECCCCCC
STDKLPVIIEYRDGTLAGSAVPNLIEGATLTDEIELIDSAAFGISKQQAAKVWETLSTDD
CCCCCEEEEEECCCEEECCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
AVKSVWLDAVVHAHKDPTNGVNALANLTPTVPLTGAYGNLAKQFNGQGVTVAVLDTGYDV
HHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEECCCCHHHHHHHCCCCEEEEEEECCCCC
QHGDLAGQVVQSKDFTYSSNGVDDLNGHGTHTAATIAGTGVESNSLWAGMAPGAKLLVGK
CCCCCHHHEECCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHEEEEH
VLTNSGAGSTSGILSGMQWAVSQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSA
HHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEC
GNSFTRETVGLPGCAPSALTVGAVDRDNNTASFSSRGPSPDGHSAKPDIASQGVDVVSAA
CCCCCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEC
SGGFGATAYRALSGTSMSAPHVSGGAAIVMQARPDLSPRQIKEVLTSSVVPTDAHVLEQG
CCCCCHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHCC
AGPMDVNRAISQSIIAPPNMELGSFAYGQDIGVTEKTISLRNLSDKDISLKLKMSLIGED
CCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCC
GKTRMPATLAGLGTNSINVPANGSAEIPVWIDSSVALRSGAYGTITGRIEGTATGKSDER
CCCCCCEEEEECCCCEEECCCCCCCEEEEEECCCEEECCCCCEEEEEEEEEEECCCCCCE
VTVPISFWIEPPQVNLSLSVTDMRGKPASSPSRVYLMNEEDDWGQAVTLRNGQASLSVPE
EEEEEEEEECCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCEEEEECC
GNYTIVANVMTYDNDSTTSGLVESATQMAVLNRKLSQDTQIEFDARNAEKLEFKASQPLA
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCC
PQGYAFGFTYALDDNKVAKLAAMELAPDYVKDIYTWSQGHDDRFRSFVTTRAFAPETVLT
CCCEEEEEEEEECCCCEEEHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEE
MQNGEVLDYNKQGLALSFDGEGRAEVVPVGDAGYSTDWTQFDLTGRIALIGNPYYLTSYM
ECCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEEEEEEEEEECCHHHHHHH
AANALKSGAIGVIFYRPGLHGRYKGTISGTPRIPVVGISSEQGEALLAQIEAGNNIVSWS
HHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCEEEECCCCCCCEEEEEEECCCEEEEEC
GTAAERTPYAYSINHITDGRISGGQVVLQEQKMQRIRASYHSQNDQRPIWTDMMAMTNST
CCCCCCCCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
GEFYSTGSSQMVMTPVVRDEYYTATSKNMWTNIVMPGIQFSTDGGYFDGPRMMTEGTVET
CCEEECCCCCEEEEEEECCCEEEECCCCCEEEEEECCEEEECCCCCCCCCEEEECCCCCH
TSWLKGPKAGSLLSNGGAIANRDTNTIDLSIVRFGDAAGHDGIGGYNSQSLYGLRVNGQN
HHHHCCCCCCCEECCCCEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCC
TYLDSGLFTLPDTNAQVELEVRSYARGVGNSSPVKDNLGSFYQGIYQFSTDSSKQGRQAV
EEECCCEEECCCCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCEEE
LTPKLDIPVAIDNTLAAGVPVEVKLSAVMDGAAQVDLSDVTLQYGYGQECSLAEIPVSIY
ECCCCCCEEEECCCCCCCCCEEEEEEEEECCCCEEEEEEEEEEECCCCCCCCEECCEEEE
CPVTSKFAESAWKTAEVKWVNGEWVATIPNDSTAGNFVHLRVQMSDGNSEAKQTMMRVYM
CCCHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHEE
LK
CC
>Mature Secondary Structure
MKQLFKRSRIAVTCLMAMGFTTSYTTLADDNVALMAAQSGAVQFTLITGEVVTAVVRADG
CHHHHHHHHHHEEEHHHHCCCCCEEEECCCCEEEEEECCCCEEEEEEEHHHHEEEEECCC
SLGGIRLLGENGAEVITSIFQNQNGQYLITPKAQKWVESQTVDIELFNISKLHAAGYDDA
CCCCEEEECCCCHHHHHHHHHCCCCCEEECCCHHHHHCCCEEEEEEEEEEEEEECCCCCC
STDKLPVIIEYRDGTLAGSAVPNLIEGATLTDEIELIDSAAFGISKQQAAKVWETLSTDD
CCCCCEEEEEECCCEEECCCCCHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCH
AVKSVWLDAVVHAHKDPTNGVNALANLTPTVPLTGAYGNLAKQFNGQGVTVAVLDTGYDV
HHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEECCCCHHHHHHHCCCCEEEEEEECCCCC
QHGDLAGQVVQSKDFTYSSNGVDDLNGHGTHTAATIAGTGVESNSLWAGMAPGAKLLVGK
CCCCCHHHEECCCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHEEEEH
VLTNSGAGSTSGILSGMQWAVSQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSA
HHCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEEC
GNSFTRETVGLPGCAPSALTVGAVDRDNNTASFSSRGPSPDGHSAKPDIASQGVDVVSAA
CCCCCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCCEEEEC
SGGFGATAYRALSGTSMSAPHVSGGAAIVMQARPDLSPRQIKEVLTSSVVPTDAHVLEQG
CCCCCHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHCC
AGPMDVNRAISQSIIAPPNMELGSFAYGQDIGVTEKTISLRNLSDKDISLKLKMSLIGED
CCCCHHHHHHHHHHCCCCCCCCCCEECCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCC
GKTRMPATLAGLGTNSINVPANGSAEIPVWIDSSVALRSGAYGTITGRIEGTATGKSDER
CCCCCCEEEEECCCCEEECCCCCCCEEEEEECCCEEECCCCCEEEEEEEEEEECCCCCCE
VTVPISFWIEPPQVNLSLSVTDMRGKPASSPSRVYLMNEEDDWGQAVTLRNGQASLSVPE
EEEEEEEEECCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCEEEEECC
GNYTIVANVMTYDNDSTTSGLVESATQMAVLNRKLSQDTQIEFDARNAEKLEFKASQPLA
CCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCC
PQGYAFGFTYALDDNKVAKLAAMELAPDYVKDIYTWSQGHDDRFRSFVTTRAFAPETVLT
CCCEEEEEEEEECCCCEEEHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEE
MQNGEVLDYNKQGLALSFDGEGRAEVVPVGDAGYSTDWTQFDLTGRIALIGNPYYLTSYM
ECCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCCCEEEEEEEEEEEEECCHHHHHHH
AANALKSGAIGVIFYRPGLHGRYKGTISGTPRIPVVGISSEQGEALLAQIEAGNNIVSWS
HHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCEEEECCCCCCCEEEEEEECCCEEEEEC
GTAAERTPYAYSINHITDGRISGGQVVLQEQKMQRIRASYHSQNDQRPIWTDMMAMTNST
CCCCCCCCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
GEFYSTGSSQMVMTPVVRDEYYTATSKNMWTNIVMPGIQFSTDGGYFDGPRMMTEGTVET
CCEEECCCCCEEEEEEECCCEEEECCCCCEEEEEECCEEEECCCCCCCCCEEEECCCCCH
TSWLKGPKAGSLLSNGGAIANRDTNTIDLSIVRFGDAAGHDGIGGYNSQSLYGLRVNGQN
HHHHCCCCCCCEECCCCEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCC
TYLDSGLFTLPDTNAQVELEVRSYARGVGNSSPVKDNLGSFYQGIYQFSTDSSKQGRQAV
EEECCCEEECCCCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCEEE
LTPKLDIPVAIDNTLAAGVPVEVKLSAVMDGAAQVDLSDVTLQYGYGQECSLAEIPVSIY
ECCCCCCEEEECCCCCCCCCEEEEEEEEECCCCEEEEEEEEEEECCCCCCCCEECCEEEE
CPVTSKFAESAWKTAEVKWVNGEWVATIPNDSTAGNFVHLRVQMSDGNSEAKQTMMRVYM
CCCHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHEE
LK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3001653; 4967581; 8512925; 9425066 [H]