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The map label for this gene is yfmJ [H]

Identifier: 113969860

GI number: 113969860

Start: 1785695

End: 1786690

Strand: Direct

Name: yfmJ [H]

Synonym: Shewmr4_1518

Alternate gene names: 113969860

Gene position: 1785695-1786690 (Clockwise)

Preceding gene: 113969858

Following gene: 113969861

Centisome position: 37.94

GC content: 44.88

Gene sequence:

>996_bases
ATGATAAGCAATCAAATTCATTTAGCATCACGTCCTACAGGTATGCCAACACAAACTAACTTTAAGTTGGTCGAGGTCAC
ATTACCCGCCTTGAAAACCGGAGAAGTGTTAGTCAAAAACACTTGGATGTCGGTCGATCCCTATATGCGCGGTCGGATGA
TCGACAAGGATTCCTATATTCCGCCATACCAAATTAATGAAGTGATGGATGGTGGCGCCATTGGTGAAGTCATTGAATCC
TTAAATCCACAATTTCCCGTTGGTGCCAAGGTGAGCCATATCAGTGGCTGGCGTAGTGCCTTTATCAGTGACGGTAGCGA
TCTCACTTTATTACCTGCAGTGAATATTCCTGAGCAGTACTTTTTAGGTATTATCGGTATGCCTGGCTTGACAGCTTGGG
TCGGTCTAATGAAAGTGGCTAAGTTAAAACCAACGGATACAGTATTTGTTTCAGCTGCATCCGGTGCGGTCGGTATGGTT
GTCTGTCAAATCGCCAAGCTTAATGGCTGTAAAGTGATTGCTTCAGTTGGCTCAGATGAAAAAGCCGAGCTCGTCAAAAG
TCTCGGTGTGGATGCGGTGATTAACTATAAAAATGTGACCGATTTAACCCAAGCACTGCGTGACGCGGCTCCAGAAGGCA
TTGATGTGTATTTTGAGAACGTCGGTGGCGCCCATCTTGAAGCTGCTTTAGATGTGATGAATGATTACGGCCGCATTTCG
GTATGTGGCATGATTGCCTATTATAATGCGCAGACGCCAGTTCCTGGTCCAAGCAATCTCTTAGCGATTAACACCAAAAA
GCTCACCATGCAGGGCTTTATTGTGATGGATTATTGGGACCAGTACAGCGAGTTTGTGGGACAGATGGCGCAGTGGTTAC
AAGAAGGCAAAATGAAGTCGGAAGAGACAGTATATCAAGGTTTAGAACAAGCTCCTGATGCATTTATCGGCTTATTCGAA
GGCAAAAATAAAGGAAAGATGCTGGTTAAACTCTAA

Upstream 100 bases:

>100_bases
TTTGCGCACAAACTATTTGCAAGCGAATAGAGTCGTGCATTGTCTACGAAAAACACATATTCCAGTTTGATGTGTGTTGG
ATTTAATAGAGGTTAACACC

Downstream 100 bases:

>100_bases
TATTGCCTTGTCTTATGGCGCTCACTGATGAGGCCAATGACACCTTGGTGTAACCAATAGGTTAACCATATAACGGAAGC
CTTTGACTGCAAAGACTTCC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MISNQIHLASRPTGMPTQTNFKLVEVTLPALKTGEVLVKNTWMSVDPYMRGRMIDKDSYIPPYQINEVMDGGAIGEVIES
LNPQFPVGAKVSHISGWRSAFISDGSDLTLLPAVNIPEQYFLGIIGMPGLTAWVGLMKVAKLKPTDTVFVSAASGAVGMV
VCQIAKLNGCKVIASVGSDEKAELVKSLGVDAVINYKNVTDLTQALRDAAPEGIDVYFENVGGAHLEAALDVMNDYGRIS
VCGMIAYYNAQTPVPGPSNLLAINTKKLTMQGFIVMDYWDQYSEFVGQMAQWLQEGKMKSEETVYQGLEQAPDAFIGLFE
GKNKGKMLVKL

Sequences:

>Translated_331_residues
MISNQIHLASRPTGMPTQTNFKLVEVTLPALKTGEVLVKNTWMSVDPYMRGRMIDKDSYIPPYQINEVMDGGAIGEVIES
LNPQFPVGAKVSHISGWRSAFISDGSDLTLLPAVNIPEQYFLGIIGMPGLTAWVGLMKVAKLKPTDTVFVSAASGAVGMV
VCQIAKLNGCKVIASVGSDEKAELVKSLGVDAVINYKNVTDLTQALRDAAPEGIDVYFENVGGAHLEAALDVMNDYGRIS
VCGMIAYYNAQTPVPGPSNLLAINTKKLTMQGFIVMDYWDQYSEFVGQMAQWLQEGKMKSEETVYQGLEQAPDAFIGLFE
GKNKGKMLVKL
>Mature_331_residues
MISNQIHLASRPTGMPTQTNFKLVEVTLPALKTGEVLVKNTWMSVDPYMRGRMIDKDSYIPPYQINEVMDGGAIGEVIES
LNPQFPVGAKVSHISGWRSAFISDGSDLTLLPAVNIPEQYFLGIIGMPGLTAWVGLMKVAKLKPTDTVFVSAASGAVGMV
VCQIAKLNGCKVIASVGSDEKAELVKSLGVDAVINYKNVTDLTQALRDAAPEGIDVYFENVGGAHLEAALDVMNDYGRIS
VCGMIAYYNAQTPVPGPSNLLAINTKKLTMQGFIVMDYWDQYSEFVGQMAQWLQEGKMKSEETVYQGLEQAPDAFIGLFE
GKNKGKMLVKL

Specific function: Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=330, Percent_Identity=40.3030303030303, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI226059133, Length=330, Percent_Identity=40.3030303030303, Blast_Score=233, Evalue=1e-61,
Organism=Homo sapiens, GI226246682, Length=345, Percent_Identity=39.1304347826087, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI226246680, Length=345, Percent_Identity=39.1304347826087, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI22748929, Length=345, Percent_Identity=39.1304347826087, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI226056130, Length=302, Percent_Identity=40.0662251655629, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI28557745, Length=330, Percent_Identity=31.2121212121212, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI194239674, Length=231, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI13236495, Length=231, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI226510941, Length=330, Percent_Identity=41.5151515151515, Blast_Score=260, Evalue=8e-71,
Organism=Escherichia coli, GI1790485, Length=172, Percent_Identity=31.3953488372093, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI133901710, Length=335, Percent_Identity=35.5223880597015, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI133901712, Length=335, Percent_Identity=35.5223880597015, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17507255, Length=230, Percent_Identity=27.3913043478261, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323504, Length=336, Percent_Identity=29.7619047619048, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319520, Length=276, Percent_Identity=27.1739130434783, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35941; Mature: 35941

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNQIHLASRPTGMPTQTNFKLVEVTLPALKTGEVLVKNTWMSVDPYMRGRMIDKDSYI
CCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHCCEEECCCCCC
PPYQINEVMDGGAIGEVIESLNPQFPVGAKVSHISGWRSAFISDGSDLTLLPAVNIPEQY
CCHHHHHHHCCCHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCEEEEECCCCCHHH
FLGIIGMPGLTAWVGLMKVAKLKPTDTVFVSAASGAVGMVVCQIAKLNGCKVIASVGSDE
HHEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCH
KAELVKSLGVDAVINYKNVTDLTQALRDAAPEGIDVYFENVGGAHLEAALDVMNDYGRIS
HHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEE
VCGMIAYYNAQTPVPGPSNLLAINTKKLTMQGFIVMDYWDQYSEFVGQMAQWLQEGKMKS
EEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCC
EETVYQGLEQAPDAFIGLFEGKNKGKMLVKL
HHHHHHHHHHCCHHEEEEEECCCCCCEEEEC
>Mature Secondary Structure
MISNQIHLASRPTGMPTQTNFKLVEVTLPALKTGEVLVKNTWMSVDPYMRGRMIDKDSYI
CCCCCEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCHHHCCEEECCCCCC
PPYQINEVMDGGAIGEVIESLNPQFPVGAKVSHISGWRSAFISDGSDLTLLPAVNIPEQY
CCHHHHHHHCCCHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCEEEEECCCCCHHH
FLGIIGMPGLTAWVGLMKVAKLKPTDTVFVSAASGAVGMVVCQIAKLNGCKVIASVGSDE
HHEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCH
KAELVKSLGVDAVINYKNVTDLTQALRDAAPEGIDVYFENVGGAHLEAALDVMNDYGRIS
HHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEE
VCGMIAYYNAQTPVPGPSNLLAINTKKLTMQGFIVMDYWDQYSEFVGQMAQWLQEGKMKS
EEEEEEEECCCCCCCCCCCEEEEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCC
EETVYQGLEQAPDAFIGLFEGKNKGKMLVKL
HHHHHHHHHHCCHHEEEEEECCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]