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The map label for this gene is iorA [H]

Identifier: 113969781

GI number: 113969781

Start: 1683808

End: 1684305

Strand: Direct

Name: iorA [H]

Synonym: Shewmr4_1439

Alternate gene names: 113969781

Gene position: 1683808-1684305 (Clockwise)

Preceding gene: 113969780

Following gene: 113969782

Centisome position: 35.78

GC content: 51.81

Gene sequence:

>498_bases
ATGGCAATACCATCCTCGGAGGCGGCAAAGGACCAGAGTCTTGCGATGCCTTCCCAAAACCTGACCATTAATGGCAGATC
TTTTACCTTAAATGCGGATCCCAATATGCCTATCCTCTGGGCGTTACGGGATATTTTAGGCTTAACGGGCACTAAATATG
GCTGCGGCGCCGGACTCTGCGGCGCCTGTACCGTGCATTTAGATGGTCAGCCTGTGCGCGCCTGTTTAACCAGCGTATCC
CAGGCGCAGGGCAAACAACTGACCACGATTGAAGGGCTGGATAATCAAAAGCTTAAAAATGCTTGGGCCGAACAGAATGT
TCCTCAGTGTGGTTATTGTCAGGCGGGGCAATTAATGTCCGCAGCAGCTTTAGTCACTCAGCATCCAAAACCGTCGGCGG
AGCAAATTGATGCTGCCATGTCGGGTAATTTGTGTCGCTGCGGTACCTATCCTCGGATAAAAGCGGCGCTGCAAAGCTAT
GCCAAACAGGAGGGCTAA

Upstream 100 bases:

>100_bases
AAATGTGGGTGAGCTAGTGGCTGTTCCCTTACCCCATGCCGCGATTGATATTGATACTAAAGCCGATCTTGCGTCGTGGT
TGGCACTTAAGGAGTGAGTT

Downstream 100 bases:

>100_bases
GATGAGTACATTCACCGCAGTTGAAAATATCAGTCGCCGCGATGTGTTAAAACTCTTCGGCGCCGTTGGGGGCGGTCTCG
CCCTTGGCGCCAGTGGCCTC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MAIPSSEAAKDQSLAMPSQNLTINGRSFTLNADPNMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVRACLTSVS
QAQGKQLTTIEGLDNQKLKNAWAEQNVPQCGYCQAGQLMSAAALVTQHPKPSAEQIDAAMSGNLCRCGTYPRIKAALQSY
AKQEG

Sequences:

>Translated_165_residues
MAIPSSEAAKDQSLAMPSQNLTINGRSFTLNADPNMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVRACLTSVS
QAQGKQLTTIEGLDNQKLKNAWAEQNVPQCGYCQAGQLMSAAALVTQHPKPSAEQIDAAMSGNLCRCGTYPRIKAALQSY
AKQEG
>Mature_164_residues
AIPSSEAAKDQSLAMPSQNLTINGRSFTLNADPNMPILWALRDILGLTGTKYGCGAGLCGACTVHLDGQPVRACLTSVSQ
AQGKQLTTIEGLDNQKLKNAWAEQNVPQCGYCQAGQLMSAAALVTQHPKPSAEQIDAAMSGNLCRCGTYPRIKAALQSYA
KQEG

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=156, Percent_Identity=37.1794871794872, Blast_Score=77, Evalue=5e-15,
Organism=Homo sapiens, GI71773480, Length=101, Percent_Identity=32.6732673267327, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=39.5061728395062, Blast_Score=111, Evalue=2e-26,
Organism=Escherichia coli, GI1789232, Length=138, Percent_Identity=38.4057971014493, Blast_Score=91, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17539860, Length=155, Percent_Identity=37.4193548387097, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=160, Percent_Identity=36.875, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17540638, Length=157, Percent_Identity=36.3057324840764, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17737937, Length=157, Percent_Identity=36.9426751592357, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24647193, Length=162, Percent_Identity=34.5679012345679, Blast_Score=83, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24647201, Length=157, Percent_Identity=32.484076433121, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=33.1288343558282, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=33.1288343558282, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24647199, Length=157, Percent_Identity=31.8471337579618, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17397; Mature: 17266

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPSSEAAKDQSLAMPSQNLTINGRSFTLNADPNMPILWALRDILGLTGTKYGCGAGLC
CCCCCCCCCCCHHHCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCC
GACTVHLDGQPVRACLTSVSQAQGKQLTTIEGLDNQKLKNAWAEQNVPQCGYCQAGQLMS
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
AAALVTQHPKPSAEQIDAAMSGNLCRCGTYPRIKAALQSYAKQEG
HHHHHHCCCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIPSSEAAKDQSLAMPSQNLTINGRSFTLNADPNMPILWALRDILGLTGTKYGCGAGLC
CCCCCCCCCCHHHCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCC
GACTVHLDGQPVRACLTSVSQAQGKQLTTIEGLDNQKLKNAWAEQNVPQCGYCQAGQLMS
CEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHH
AAALVTQHPKPSAEQIDAAMSGNLCRCGTYPRIKAALQSYAKQEG
HHHHHHCCCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]