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The map label for this gene is hcaT [H]

Identifier: 113969759

GI number: 113969759

Start: 1654302

End: 1655471

Strand: Direct

Name: hcaT [H]

Synonym: Shewmr4_1417

Alternate gene names: 113969759

Gene position: 1654302-1655471 (Clockwise)

Preceding gene: 113969758

Following gene: 113969760

Centisome position: 35.15

GC content: 52.82

Gene sequence:

>1170_bases
ATGCCAACAATCTCTAGCACAAGCCAGCAGTTACGCTGGCTATGTGCCTGTTATTTTTTCTTCTTTTCAATTCTCGGCAC
TATGATCCCTTACCTTGGGGTCTTCTTCGAAAACCGTGGATTTAACCCTCAAGAAATCGGTTTTTTGCTGGCGATTTTAA
TGGCGACCCGAATCGTGGCACCCAATGTGTGGGCTAAGGTGGCCGATCGCACTGGCATGCGCTCCGAATTGGTGAAGATG
GGCGCGGGCGCCGCGATGCTGGCGTATTTGAGTTTCTTCTACCACGGTGGCTTTGTGTATATGGCGCTGAGCCTTGCGCT
GTATACCTTCTTCTGGAACGCGATTTTGGCACAGCTTGAGGTGATCACCCTCGAAACCTTAGGTGAAAATGCCAGCCGCT
ATGGACAAATCCGCAGTTTTGGCAGCATTGGCTATATCTGCTTGGTGGTCGGTGCCGGTTTTGCCATCGGCCAATGGGGC
ACTGAGGTGTTGCCTTATATTGGTTTAGCCTTGTTTACAGGGATGCTGGTCAGCGCCTTGCCGTTGCCCGCGAATCGTGC
CGTGCGCCCTCAAGGGCAGGAGCGGCAGCCGCTCAAATGGACTAAGCCCATTCTGTGGTTCATGGTATCGGCGATGTTAT
TACAGATGAGCGCTGGGCCTTTTTACGGTTTCTTTGTGCTCTATCTTAAGCAGGCGGGTTACACTGAAGCGGCCGCGGGG
ATTTTTGTTGCCTTAGGGGCAATGGCCGAAATCGTGATGTTTATGTTTGCGCCTCGCTTGCTTGGACGGTATGGCGTCAA
TACCTTGCTTGTCGTCAGTATTGCTATGACTGCCGTGCGTTGGTTGCTGGTCGCCTTCGGCGTTGAGAGCATGTTATTAC
TGGGCTTAAGCCAAGTGCTGCATGCGTTCACCTTCGGTTTGACCCATGCGGCCTCGATTCAGTTTGTGCACCGAAATTTT
GATGCCAGTCATCGCAGTCAAGGACAAGCCCTGTATGCCAGCTTAAGCTTTGGGGTTGGCGGCGCACTCGGAACGTGGAT
TTGCGGTTATATCTGGGGGGATGGTAGCGGCGCTGTATGGTCTTGGGTATTTGCGGCGGCCTGTGCCTTTGCGGCCATGT
TAGCGGTATTTTTGATCCCTAAGGATAGGCCGCAAGCAGTTGCTGCATAA

Upstream 100 bases:

>100_bases
CAGTCACACACCGATTCTCGGCATGAGATAGGTGCGATGAATGAGACAGTCTGCATGGAATAAAGATGCATAGCGGCTGT
GTAATAAATGGAATGCGTTA

Downstream 100 bases:

>100_bases
GCTTATATTTTATTGTGAAAAATAACTCATTGTAAAAACTAGAATAATTAACAAGAGAGGTTAAGGTGATCCGGTTTCGT
TTAGGCTTAGTCATCAATCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MPTISSTSQQLRWLCACYFFFFSILGTMIPYLGVFFENRGFNPQEIGFLLAILMATRIVAPNVWAKVADRTGMRSELVKM
GAGAAMLAYLSFFYHGGFVYMALSLALYTFFWNAILAQLEVITLETLGENASRYGQIRSFGSIGYICLVVGAGFAIGQWG
TEVLPYIGLALFTGMLVSALPLPANRAVRPQGQERQPLKWTKPILWFMVSAMLLQMSAGPFYGFFVLYLKQAGYTEAAAG
IFVALGAMAEIVMFMFAPRLLGRYGVNTLLVVSIAMTAVRWLLVAFGVESMLLLGLSQVLHAFTFGLTHAASIQFVHRNF
DASHRSQGQALYASLSFGVGGALGTWICGYIWGDGSGAVWSWVFAAACAFAAMLAVFLIPKDRPQAVAA

Sequences:

>Translated_389_residues
MPTISSTSQQLRWLCACYFFFFSILGTMIPYLGVFFENRGFNPQEIGFLLAILMATRIVAPNVWAKVADRTGMRSELVKM
GAGAAMLAYLSFFYHGGFVYMALSLALYTFFWNAILAQLEVITLETLGENASRYGQIRSFGSIGYICLVVGAGFAIGQWG
TEVLPYIGLALFTGMLVSALPLPANRAVRPQGQERQPLKWTKPILWFMVSAMLLQMSAGPFYGFFVLYLKQAGYTEAAAG
IFVALGAMAEIVMFMFAPRLLGRYGVNTLLVVSIAMTAVRWLLVAFGVESMLLLGLSQVLHAFTFGLTHAASIQFVHRNF
DASHRSQGQALYASLSFGVGGALGTWICGYIWGDGSGAVWSWVFAAACAFAAMLAVFLIPKDRPQAVAA
>Mature_388_residues
PTISSTSQQLRWLCACYFFFFSILGTMIPYLGVFFENRGFNPQEIGFLLAILMATRIVAPNVWAKVADRTGMRSELVKMG
AGAAMLAYLSFFYHGGFVYMALSLALYTFFWNAILAQLEVITLETLGENASRYGQIRSFGSIGYICLVVGAGFAIGQWGT
EVLPYIGLALFTGMLVSALPLPANRAVRPQGQERQPLKWTKPILWFMVSAMLLQMSAGPFYGFFVLYLKQAGYTEAAAGI
FVALGAMAEIVMFMFAPRLLGRYGVNTLLVVSIAMTAVRWLLVAFGVESMLLLGLSQVLHAFTFGLTHAASIQFVHRNFD
ASHRSQGQALYASLSFGVGGALGTWICGYIWGDGSGAVWSWVFAAACAFAAMLAVFLIPKDRPQAVAA

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=396, Percent_Identity=25.7575757575758, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 42453; Mature: 42321

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTISSTSQQLRWLCACYFFFFSILGTMIPYLGVFFENRGFNPQEIGFLLAILMATRIVA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PNVWAKVADRTGMRSELVKMGAGAAMLAYLSFFYHGGFVYMALSLALYTFFWNAILAQLE
CHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VITLETLGENASRYGQIRSFGSIGYICLVVGAGFAIGQWGTEVLPYIGLALFTGMLVSAL
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PLPANRAVRPQGQERQPLKWTKPILWFMVSAMLLQMSAGPFYGFFVLYLKQAGYTEAAAG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHH
IFVALGAMAEIVMFMFAPRLLGRYGVNTLLVVSIAMTAVRWLLVAFGVESMLLLGLSQVL
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAFTFGLTHAASIQFVHRNFDASHRSQGQALYASLSFGVGGALGTWICGYIWGDGSGAVW
HHHHHHHHHHHHHHHHHHCCCCCHHCCCCEEEEEHHCCCCHHHHHHHHHHEEECCCCHHH
SWVFAAACAFAAMLAVFLIPKDRPQAVAA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PTISSTSQQLRWLCACYFFFFSILGTMIPYLGVFFENRGFNPQEIGFLLAILMATRIVA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PNVWAKVADRTGMRSELVKMGAGAAMLAYLSFFYHGGFVYMALSLALYTFFWNAILAQLE
CHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VITLETLGENASRYGQIRSFGSIGYICLVVGAGFAIGQWGTEVLPYIGLALFTGMLVSAL
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PLPANRAVRPQGQERQPLKWTKPILWFMVSAMLLQMSAGPFYGFFVLYLKQAGYTEAAAG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHH
IFVALGAMAEIVMFMFAPRLLGRYGVNTLLVVSIAMTAVRWLLVAFGVESMLLLGLSQVL
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAFTFGLTHAASIQFVHRNFDASHRSQGQALYASLSFGVGGALGTWICGYIWGDGSGAVW
HHHHHHHHHHHHHHHHHHCCCCCHHCCCCEEEEEHHCCCCHHHHHHHHHHEEECCCCHHH
SWVFAAACAFAAMLAVFLIPKDRPQAVAA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]