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The map label for this gene is rfbC [H]

Identifier: 113969681

GI number: 113969681

Start: 1552172

End: 1552714

Strand: Direct

Name: rfbC [H]

Synonym: Shewmr4_1339

Alternate gene names: 113969681

Gene position: 1552172-1552714 (Clockwise)

Preceding gene: 113969680

Following gene: 113969694

Centisome position: 32.98

GC content: 46.04

Gene sequence:

>543_bases
ATGAAGTGCATTGAAACCGAGCTTGCAGAAGTATTGGTGTTCGAACCGCAAGTATTTGGTGATGAACGCGGTTTTTTTAT
GGAAACATTTCGGCAGTCGTATTTCACTGAATGTTTTCAAAGTCGAGGATTAAAGGCGCCTGAGTTGGTGCAAGATAATT
ACAGTCGCTCACAACAACACGTATTACGTGGCTTGCACTACCAATGCAAGCATCCGCAGGGCAAATTAGTCCGTGTTTGT
GCAGGCAGTATTTTTGATGTCGCTGTGGATATTCGGCCGCAATCAGAAACCTATGGTAAATGGGTAGGGCGTGTGCTTTC
TGCTGATAACCATTTGCAAATGTGGATCCCGCCTGGCTTTGCCCATGGTTTTTATGTGCTGAGTGAATATGCCGATGTGA
TTTATCGCTGCACTGATTATTACGCGCCAGATGATGAATATGTGCTGGCATGGAATAGTGCTGAGTTTGCAATTGACTGG
CCGTTACGCAACGAACCACCAATACTTTCGGAGAGGGATGCAAAAGCCGCCGTGAGTACCTAG

Upstream 100 bases:

>100_bases
GGTTGGATAGATGCTGCGCAGCTTACTGCTTTAGCACAACCTTTGCTTAAAAGCGGTTATGGTGAGTATCTTTTAGGATT
ATTAAATAAGCAGGTGTTTA

Downstream 100 bases:

>100_bases
CTTTAGGTACTCACGGCATTATGCATTATTTGACAGACTCACTTGTGATGCTTGCACGTGTGAACCAAGGATCTCTAGCA
TCCATTACATCATATAGACT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSYFTECFQSRGLKAPELVQDNYSRSQQHVLRGLHYQCKHPQGKLVRVC
AGSIFDVAVDIRPQSETYGKWVGRVLSADNHLQMWIPPGFAHGFYVLSEYADVIYRCTDYYAPDDEYVLAWNSAEFAIDW
PLRNEPPILSERDAKAAVST

Sequences:

>Translated_180_residues
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSYFTECFQSRGLKAPELVQDNYSRSQQHVLRGLHYQCKHPQGKLVRVC
AGSIFDVAVDIRPQSETYGKWVGRVLSADNHLQMWIPPGFAHGFYVLSEYADVIYRCTDYYAPDDEYVLAWNSAEFAIDW
PLRNEPPILSERDAKAAVST
>Mature_180_residues
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSYFTECFQSRGLKAPELVQDNYSRSQQHVLRGLHYQCKHPQGKLVRVC
AGSIFDVAVDIRPQSETYGKWVGRVLSADNHLQMWIPPGFAHGFYVLSEYADVIYRCTDYYAPDDEYVLAWNSAEFAIDW
PLRNEPPILSERDAKAAVST

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=177, Percent_Identity=52.5423728813559, Blast_Score=182, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17550412, Length=172, Percent_Identity=47.093023255814, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20759; Mature: 20759

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSYFTECFQSRGLKAPELVQDNYSRSQQH
CCCHHHHHHHHHEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VLRGLHYQCKHPQGKLVRVCAGSIFDVAVDIRPQSETYGKWVGRVLSADNHLQMWIPPGF
HHHCCCCCCCCCCCCEEHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCH
AHGFYVLSEYADVIYRCTDYYAPDDEYVLAWNSAEFAIDWPLRNEPPILSERDAKAAVST
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKCIETELAEVLVFEPQVFGDERGFFMETFRQSYFTECFQSRGLKAPELVQDNYSRSQQH
CCCHHHHHHHHHEECCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VLRGLHYQCKHPQGKLVRVCAGSIFDVAVDIRPQSETYGKWVGRVLSADNHLQMWIPPGF
HHHCCCCCCCCCCCCEEHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCH
AHGFYVLSEYADVIYRCTDYYAPDDEYVLAWNSAEFAIDWPLRNEPPILSERDAKAAVST
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7961452; 8655518 [H]