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The map label for this gene is ugd [H]

Identifier: 113969673

GI number: 113969673

Start: 1541694

End: 1542860

Strand: Direct

Name: ugd [H]

Synonym: Shewmr4_1330

Alternate gene names: 113969673

Gene position: 1541694-1542860 (Clockwise)

Preceding gene: 113969672

Following gene: 113969674

Centisome position: 32.76

GC content: 41.39

Gene sequence:

>1167_bases
ATGAAAATTGCTATTGCTGGTACAGGTTATGTAGGTTTATCTAATGCTGTGCTTTTGGCACAGTACCATCAAGTTACTGC
GGTTGATGTTATCGCGGGTAAAGTGGAGTTAATTAACGCTCGCAAATCACCGATTGTTGATGCTGAAATTGAAGAATATC
TGGCGCAGCGCGAGCTTAATTTAACCGCGACCTTGGATAAACAACTGGCGTATGAAGATGCTGATTTTGTAATTATTGCT
ACGCCAACGGATTACGATCCAAAAACGAATTATTTTAACACTTCTACTGTTGAGTCGGTCATTCAAGATGTGTTAGCCAT
TAACCCTAATGCGGTGATGGTGATTAAAAGCACAGTACCGGTTGGTTTTACCGCCAAGGTTAAGCAAAAGTTCCAGTGCG
AAAATATTTTATTCTCCCCAGAGTTTTTGCGTGAGGGGAAAGCGCTTTACGATAACTTGCATCCATCGCGGATTATTGTC
GGTGAGCGTAGCGAGCGCGCAAAAATATTTGCTGATTTATTAGTGCAAGGCGCAGTGAGAAAAGATATTGAAGTTTTATT
TACTGATTCGACCGAGGCCGAAGCGGTTAAATTATTCTCTAATACTTATCTTGCGATGCGTGTAGCTTACTTTAATGAGC
TTGATACTTATGCTGAGACTCATGGTTTAGATTCGCGCCAAATAATCGAAGGTGTGTGTTTAGATCCACGTATTGGTAAT
CACTACAATAATCCATCCTTTGGTTATGGTGGTTACTGTTTACCTAAAGATACTAAGCAATTACGGGCTAATTATGCAGA
TGTACCTAATAGCATTATTGGCGCTATCGTTGAGTCAAACACGACCCGTAAAGATTTTATTGCTGACTCTATTTTAAGCC
GCAACCCTAAGGTTGTGGGGATTTATCGCCTAATTATGAAGTCGGGTTCGGATAACTTTCGCGCCTCCAGCATTCAAGGC
ATTATGAAGCGCCTTAAAGCTAAAGGCATTGAGGTCATTGTGTATGAGCCAGTACTTAAAGAGAAAGAGTTTTTCCATTC
TCGTGTTGTGACAGATTTGACCGCTTTCAAAGCGGTTGCCGATGTGATTGTGTCTAACCGTATGGCTAAAGAGTTAGCCG
ATGTGGCGGATAAGGTTTATACGCGCGATTTGTTTGGAAGTGATTGA

Upstream 100 bases:

>100_bases
GAGTCAAATTCTAGCGAAAAGGCTATTTCGCTTGTTAACTTGATTTTGGGATGTGTAGTCGATATTTAAGTCGCCATCTT
TTTACGTATATGAGTTAAAA

Downstream 100 bases:

>100_bases
CGAAAGCCTGCGGTCAGAGCGCCCGCTTTGCGGGCTTATAGAGCGCAGCGTAAACGCTGCTTCGAGGTTCTAGTTGCGAA
TATACGAGCGCTCTGCTTTA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIAIAGTGYVGLSNAVLLAQYHQVTAVDVIAGKVELINARKSPIVDAEIEEYLAQRELNLTATLDKQLAYEDADFVIIA
TPTDYDPKTNYFNTSTVESVIQDVLAINPNAVMVIKSTVPVGFTAKVKQKFQCENILFSPEFLREGKALYDNLHPSRIIV
GERSERAKIFADLLVQGAVRKDIEVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAETHGLDSRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSIIGAIVESNTTRKDFIADSILSRNPKVVGIYRLIMKSGSDNFRASSIQG
IMKRLKAKGIEVIVYEPVLKEKEFFHSRVVTDLTAFKAVADVIVSNRMAKELADVADKVYTRDLFGSD

Sequences:

>Translated_388_residues
MKIAIAGTGYVGLSNAVLLAQYHQVTAVDVIAGKVELINARKSPIVDAEIEEYLAQRELNLTATLDKQLAYEDADFVIIA
TPTDYDPKTNYFNTSTVESVIQDVLAINPNAVMVIKSTVPVGFTAKVKQKFQCENILFSPEFLREGKALYDNLHPSRIIV
GERSERAKIFADLLVQGAVRKDIEVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAETHGLDSRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSIIGAIVESNTTRKDFIADSILSRNPKVVGIYRLIMKSGSDNFRASSIQG
IMKRLKAKGIEVIVYEPVLKEKEFFHSRVVTDLTAFKAVADVIVSNRMAKELADVADKVYTRDLFGSD
>Mature_388_residues
MKIAIAGTGYVGLSNAVLLAQYHQVTAVDVIAGKVELINARKSPIVDAEIEEYLAQRELNLTATLDKQLAYEDADFVIIA
TPTDYDPKTNYFNTSTVESVIQDVLAINPNAVMVIKSTVPVGFTAKVKQKFQCENILFSPEFLREGKALYDNLHPSRIIV
GERSERAKIFADLLVQGAVRKDIEVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAETHGLDSRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSIIGAIVESNTTRKDFIADSILSRNPKVVGIYRLIMKSGSDNFRASSIQG
IMKRLKAKGIEVIVYEPVLKEKEFFHSRVVTDLTAFKAVADVIVSNRMAKELADVADKVYTRDLFGSD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=383, Percent_Identity=26.1096605744125, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI296040438, Length=269, Percent_Identity=27.1375464684015, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI296040443, Length=233, Percent_Identity=27.4678111587983, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=75.2577319587629, Blast_Score=622, Evalue=1e-180,
Organism=Escherichia coli, GI48994968, Length=280, Percent_Identity=26.0714285714286, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560350, Length=400, Percent_Identity=28.75, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI17136908, Length=384, Percent_Identity=26.3020833333333, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43104; Mature: 43104

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIAGTGYVGLSNAVLLAQYHQVTAVDVIAGKVELINARKSPIVDAEIEEYLAQRELN
CEEEEEECCCCCCCCCEEEEHHHHHEEEHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCC
LTATLDKQLAYEDADFVIIATPTDYDPKTNYFNTSTVESVIQDVLAINPNAVMVIKSTVP
EEEEHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
VGFTAKVKQKFQCENILFSPEFLREGKALYDNLHPSRIIVGERSERAKIFADLLVQGAVR
CCEEHHHHHHHHHHHCEECHHHHHCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHH
KDIEVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAETHGLDSRQIIEGVCLDPRIGN
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCEECCCCCCC
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSIIGAIVESNTTRKDFIADSILSRNPKVVG
CCCCCCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEH
IYRLIMKSGSDNFRASSIQGIMKRLKAKGIEVIVYEPVLKEKEFFHSRVVTDLTAFKAVA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
DVIVSNRMAKELADVADKVYTRDLFGSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIAIAGTGYVGLSNAVLLAQYHQVTAVDVIAGKVELINARKSPIVDAEIEEYLAQRELN
CEEEEEECCCCCCCCCEEEEHHHHHEEEHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCC
LTATLDKQLAYEDADFVIIATPTDYDPKTNYFNTSTVESVIQDVLAINPNAVMVIKSTVP
EEEEHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCC
VGFTAKVKQKFQCENILFSPEFLREGKALYDNLHPSRIIVGERSERAKIFADLLVQGAVR
CCEEHHHHHHHHHHHCEECHHHHHCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHH
KDIEVLFTDSTEAEAVKLFSNTYLAMRVAYFNELDTYAETHGLDSRQIIEGVCLDPRIGN
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCEECCCCCCC
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSIIGAIVESNTTRKDFIADSILSRNPKVVG
CCCCCCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEH
IYRLIMKSGSDNFRASSIQGIMKRLKAKGIEVIVYEPVLKEKEFFHSRVVTDLTAFKAVA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
DVIVSNRMAKELADVADKVYTRDLFGSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7682279 [H]