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The map label for this gene is atoS [H]

Identifier: 113969622

GI number: 113969622

Start: 1486269

End: 1487351

Strand: Direct

Name: atoS [H]

Synonym: Shewmr4_1279

Alternate gene names: 113969622

Gene position: 1486269-1487351 (Clockwise)

Preceding gene: 113969621

Following gene: 113969623

Centisome position: 31.58

GC content: 50.97

Gene sequence:

>1083_bases
ATGTCAGCCCATCCACTAGCGCAACTTGAAACATTCAAGCACACTAGCAAACAATGGAACCAACTGCGTGAGGCCGCCAA
TATGTCCAATCGGATGGAGCATATTTTACAGGCTATGCCCTCTGGCGTGGTGATTTTGAACGGTGACGGTATTGTCACCG
ATGCAAACCCTGTTGCCGTGGAATTGCTGGAGCAGCCGTTATGCGGCGCCCGCTGGATTGATGTGATCCATACGGCGTTT
GCGCCACAGGATGATGATGGTCATGAAGTCTCATTACGCAATGGCCGCCGAGTCAAATTTGCGATTACCCCATTAACGCC
AGAACCGGGCCAATTAATTGTGCTGACGGATCTAACAGAAACCCGTCTACTGCAAAAGAATCTTTCCCATCTGCAGCGCC
TATCTGCCCTCGGTAAAATGGTCGCGACGCTGGCGCATCAGGTGCGTACGCCACTGTCGGCGGCACTGCTCTATGCTGCG
AATCTGGCCAGTCCCAAATTATCGGAATCAGCTAAGGCAAAATTTCAGCAGAAGTTAGTGGATAGACTCAATGAGCTTGA
ACGCCAAGTTAACGATATGCTGTTGATGGCCAAAGGGCGGCAGGATGAATTGGGTGAGTTAGTTAACCTTGATGAGGTGA
TCAATACTGTCATGGCGAACTGTGAGCCGATTGTGGCTCAGCGCGGCGCAGCATTGACTGTCACCAATGCGTCCAACGGT
TTAATGCTGGCGAATGTGAACGCGCTCAGTTCAGCCGTGAATAATCTGGTGATGAATAGCCTTGAAGCTGGGGCAACGCA
GATCCAAATCGTTGCCAATGATATCGGCGAGCAGTTAGCCCTCAATGTGGTCGACAATGGCAAAGGACTGGATGCTAAGA
TGCAACAAAAAGTGTTGGAGCCTTTCTTTACCACCAAAGCGCAAGGAACGGGTCTAGGCTTAGCCGTTGTGCAGTCCGTG
GTTCGCAATCATGGCGGCCAAATCCAATTGAGTTGTATGCCCAATAAAGGTTGTACTGTGTCGCTAACCTTCCCGCAGGC
GAAATCGGCTGCAGTATTGCCGCTGGAGAAACCCTATGTCTGA

Upstream 100 bases:

>100_bases
CTGTTGTTTATCCTATTGTTTTACCTATCTAAATTCATTTCTTAATTTGGCATAGAATCTGCAAACACTCCGTCAGAAGC
AATTTTTTGACGGAGTGACT

Downstream 100 bases:

>100_bases
AGCCAAATTACTCTTAGTCGAAGACGATGCGTCCCTGCGTGAGGCTTTGCTCGATACCTTAATGTTGGCGCAATACGACT
GCATCGATGTGGCCTCCGGC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSAHPLAQLETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAVELLEQPLCGARWIDVIHTAF
APQDDDGHEVSLRNGRRVKFAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYAA
NLASPKLSESAKAKFQQKLVDRLNELERQVNDMLLMAKGRQDELGELVNLDEVINTVMANCEPIVAQRGAALTVTNASNG
LMLANVNALSSAVNNLVMNSLEAGATQIQIVANDIGEQLALNVVDNGKGLDAKMQQKVLEPFFTTKAQGTGLGLAVVQSV
VRNHGGQIQLSCMPNKGCTVSLTFPQAKSAAVLPLEKPYV

Sequences:

>Translated_360_residues
MSAHPLAQLETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAVELLEQPLCGARWIDVIHTAF
APQDDDGHEVSLRNGRRVKFAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYAA
NLASPKLSESAKAKFQQKLVDRLNELERQVNDMLLMAKGRQDELGELVNLDEVINTVMANCEPIVAQRGAALTVTNASNG
LMLANVNALSSAVNNLVMNSLEAGATQIQIVANDIGEQLALNVVDNGKGLDAKMQQKVLEPFFTTKAQGTGLGLAVVQSV
VRNHGGQIQLSCMPNKGCTVSLTFPQAKSAAVLPLEKPYV
>Mature_359_residues
SAHPLAQLETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAVELLEQPLCGARWIDVIHTAFA
PQDDDGHEVSLRNGRRVKFAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYAAN
LASPKLSESAKAKFQQKLVDRLNELERQVNDMLLMAKGRQDELGELVNLDEVINTVMANCEPIVAQRGAALTVTNASNGL
MLANVNALSSAVNNLVMNSLEAGATQIQIVANDIGEQLALNVVDNGKGLDAKMQQKVLEPFFTTKAQGTGLGLAVVQSVV
RNHGGQIQLSCMPNKGCTVSLTFPQAKSAAVLPLEKPYV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=28.099173553719, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=33.7606837606838, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=25.7918552036199, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786600, Length=350, Percent_Identity=22.5714285714286, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=265, Percent_Identity=24.1509433962264, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI145693157, Length=352, Percent_Identity=23.8636363636364, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=26.5116279069767, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38834; Mature: 38703

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHPLAQLETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHHHH
ELLEQPLCGARWIDVIHTAFAPQDDDGHEVSLRNGRRVKFAITPLTPEPGQLIVLTDLTE
HHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEEECCHH
TRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYAANLASPKLSESAKAKFQQKLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
DRLNELERQVNDMLLMAKGRQDELGELVNLDEVINTVMANCEPIVAQRGAALTVTNASNG
HHHHHHHHHHHHHEEEECCCHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCEEEEEECCCC
LMLANVNALSSAVNNLVMNSLEAGATQIQIVANDIGEQLALNVVDNGKGLDAKMQQKVLE
EEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCHHHEEEEECCCCCCCHHHHHHHHH
PFFTTKAQGTGLGLAVVQSVVRNHGGQIQLSCMPNKGCTVSLTFPQAKSAAVLPLEKPYV
HHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCEECCCCCCCC
>Mature Secondary Structure 
SAHPLAQLETFKHTSKQWNQLREAANMSNRMEHILQAMPSGVVILNGDGIVTDANPVAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCHHHH
ELLEQPLCGARWIDVIHTAFAPQDDDGHEVSLRNGRRVKFAITPLTPEPGQLIVLTDLTE
HHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEEECCHH
TRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYAANLASPKLSESAKAKFQQKLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
DRLNELERQVNDMLLMAKGRQDELGELVNLDEVINTVMANCEPIVAQRGAALTVTNASNG
HHHHHHHHHHHHHEEEECCCHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCEEEEEECCCC
LMLANVNALSSAVNNLVMNSLEAGATQIQIVANDIGEQLALNVVDNGKGLDAKMQQKVLE
EEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCHHHEEEEECCCCCCCHHHHHHHHH
PFFTTKAQGTGLGLAVVQSVVRNHGGQIQLSCMPNKGCTVSLTFPQAKSAAVLPLEKPYV
HHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]