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The map label for this gene is ntrC [H]

Identifier: 113969621

GI number: 113969621

Start: 1484727

End: 1486160

Strand: Direct

Name: ntrC [H]

Synonym: Shewmr4_1278

Alternate gene names: 113969621

Gene position: 1484727-1486160 (Clockwise)

Preceding gene: 113969620

Following gene: 113969622

Centisome position: 31.55

GC content: 47.49

Gene sequence:

>1434_bases
ATGATGCAAACAGATCAACGAATTTTACTTGTCGGAACCCCATCAGAGCGCTTAAGTCGCCTGTGTTGCATTTTTGAATT
TTTAGGTGAGCAGATTGAAATCATCTCCACCGAAAAGTTGAGCTCTTGTCTCCAAGATACCCGTTATCGTGCCTTAGTGC
TGACAACTGACAATATGTCTGTTGAGGCATTGAAATCACTCGCTAATCAGTACCCGTGGCAACCTATTTTATTGTTTGGC
AACGTCGGTGATCTGCAAGTATCGAATGTGCTTGGTCAAATCGAAGAGCCATTAAACTATCCGCAACTCACTGAACTGCT
GCATTTTTGCCAAGTGTATGGCCAGGTTAAACGTCCTCAAGTGCCAACCAGTGCGAATCAAACCAAACTATTCCGTAGTT
TAGTGGGCCGCAGTGAAGGTATTGCCAATGTTCGCCATTTGATTAGCCAGGTTGCGACCTCTGATGCGACAGTATTAGTG
CTAGGGCAGTCGGGTACAGGTAAGGAAGTCGTCGCTCGTAACATTCATTATTTGTCTGAACGCCGTGATGGTCCTTTTAT
TCCGGTTAACTGTGGTGCGATCCCGCCAGAACTACTCGAAAGCGAATTATTTGGTCATGAGAAGGGCTCTTTTACAGGCG
CCATTAGCTCGCGTAAGGGCCGTTTTGAGCTCGCAGAAGGTGGCACACTGTTTCTCGATGAAATCGGCGATATGCCTTTG
CAGATGCAGGTAAAATTGCTGCGTGTGCTGCAGGAGCGCGTATTCGAGCGTGTCGGTGGCACTAAGACTATCAATGCTGA
TGTGCGTGTTGTCGCTGCAACCCACAGAGATCTCGAAAGCATGATCACCAGCAACGAGTTCCGTGAAGATCTTTACTATC
GCCTCAACGTTTTTCCGATTGAGATGCCTGCGCTAAGCGACCGCAAGGATGACGTTCCTCTACTGTTGCAAGAGCTGGTA
AGCCGAGTCTATAACGAAGGACGTGGCAAAGTTCGCTTTACCCAACGTGCTATTGAATCGTTAAAAGAACACGCTTGGTC
GGGTAACGTGCGTGAACTGTCGAACTTGGTTGAGCGCTTAACGATTTTATATCCTGGCGGTTTAGTCGATGTGAATGACT
TGCCTATCAAGTATCGCCATATTGATGTGCCCGAATACAGCATCGAACTCAGTGAGGAACAACAGGAACGTGATGCGTTA
GCATCCATCTTCACTAGTGAAGAGCCGGTTGAAATTCCTGAAACCCGTTTCCCGAGTGAATTACCGCCAGAAGGGGTCAA
CCTTAAGGATCTGCTGGCTGAGCTTGAAATCGATATGATTCGCCAAGCGTTAGAGCAGCAGGATAACGTCGTTGCGCGTG
CGGCAGAAATGCTCGGTATTCGTCGTACTACTTTGGTTGAGAAAATGCGTAAGTACGGAATGACGAAAGAATAG

Upstream 100 bases:

>100_bases
TGGCACAGATTGTTACATTGAATTTGTTAAGCTTTTACAGCAACTAATCATAAATAATTAATGCGAATTGATACCTAATT
AGCGCTTTACGGCCTACTGA

Downstream 100 bases:

>100_bases
TCATATTCCTGTTGTTTATCCTATTGTTTTACCTATCTAAATTCATTTCTTAATTTGGCATAGAATCTGCAAACACTCCG
TCAGAAGCAATTTTTTGACG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIEIISTEKLSSCLQDTRYRALVLTTDNMSVEALKSLANQYPWQPILLFG
NVGDLQVSNVLGQIEEPLNYPQLTELLHFCQVYGQVKRPQVPTSANQTKLFRSLVGRSEGIANVRHLISQVATSDATVLV
LGQSGTGKEVVARNIHYLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEIGDMPL
QMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLESMITSNEFREDLYYRLNVFPIEMPALSDRKDDVPLLLQELV
SRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPIKYRHIDVPEYSIELSEEQQERDAL
ASIFTSEEPVEIPETRFPSELPPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMTKE

Sequences:

>Translated_477_residues
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIEIISTEKLSSCLQDTRYRALVLTTDNMSVEALKSLANQYPWQPILLFG
NVGDLQVSNVLGQIEEPLNYPQLTELLHFCQVYGQVKRPQVPTSANQTKLFRSLVGRSEGIANVRHLISQVATSDATVLV
LGQSGTGKEVVARNIHYLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEIGDMPL
QMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLESMITSNEFREDLYYRLNVFPIEMPALSDRKDDVPLLLQELV
SRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPIKYRHIDVPEYSIELSEEQQERDAL
ASIFTSEEPVEIPETRFPSELPPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMTKE
>Mature_477_residues
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIEIISTEKLSSCLQDTRYRALVLTTDNMSVEALKSLANQYPWQPILLFG
NVGDLQVSNVLGQIEEPLNYPQLTELLHFCQVYGQVKRPQVPTSANQTKLFRSLVGRSEGIANVRHLISQVATSDATVLV
LGQSGTGKEVVARNIHYLSERRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEIGDMPL
QMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLESMITSNEFREDLYYRLNVFPIEMPALSDRKDDVPLLLQELV
SRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPIKYRHIDVPEYSIELSEEQQERDAL
ASIFTSEEPVEIPETRFPSELPPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMTKE

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=355, Percent_Identity=42.5352112676056, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1789087, Length=350, Percent_Identity=43.1428571428571, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1788550, Length=327, Percent_Identity=43.4250764525994, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1790437, Length=419, Percent_Identity=37.4701670644391, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI1790299, Length=462, Percent_Identity=33.5497835497836, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1788905, Length=214, Percent_Identity=54.2056074766355, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789233, Length=345, Percent_Identity=41.1594202898551, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI87082152, Length=342, Percent_Identity=37.1345029239766, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI87081872, Length=342, Percent_Identity=35.672514619883, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1786524, Length=351, Percent_Identity=36.1823361823362, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787583, Length=355, Percent_Identity=31.5492957746479, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI87081858, Length=329, Percent_Identity=30.3951367781155, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789828, Length=235, Percent_Identity=36.5957446808511, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 53886; Mature: 53886

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIEIISTEKLSSCLQDTRYRALVLTTDNMS
CCCCCCEEEEEECCHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHHCCCEEEEEEECCCC
VEALKSLANQYPWQPILLFGNVGDLQVSNVLGQIEEPLNYPQLTELLHFCQVYGQVKRPQ
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
VPTSANQTKLFRSLVGRSEGIANVRHLISQVATSDATVLVLGQSGTGKEVVARNIHYLSE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
RRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEIGDMPL
CCCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEECCCCCCCEEECCCCEEEEHHHCCCCH
QMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLESMITSNEFREDLYYRLNVFPI
HHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHEEEEEEEE
EMPALSDRKDDVPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERL
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TILYPGGLVDVNDLPIKYRHIDVPEYSIELSEEQQERDALASIFTSEEPVEIPETRFPSE
HHCCCCCEEECCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LPPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMTKE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMQTDQRILLVGTPSERLSRLCCIFEFLGEQIEIISTEKLSSCLQDTRYRALVLTTDNMS
CCCCCCEEEEEECCHHHHHHHHHHHHHHCCHHEEECHHHHHHHHHHCCCEEEEEEECCCC
VEALKSLANQYPWQPILLFGNVGDLQVSNVLGQIEEPLNYPQLTELLHFCQVYGQVKRPQ
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
VPTSANQTKLFRSLVGRSEGIANVRHLISQVATSDATVLVLGQSGTGKEVVARNIHYLSE
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
RRDGPFIPVNCGAIPPELLESELFGHEKGSFTGAISSRKGRFELAEGGTLFLDEIGDMPL
CCCCCEEEEECCCCCHHHHHHHHCCCCCCCEEEECCCCCCCEEECCCCEEEEHHHCCCCH
QMQVKLLRVLQERVFERVGGTKTINADVRVVAATHRDLESMITSNEFREDLYYRLNVFPI
HHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHEEEEEEEE
EMPALSDRKDDVPLLLQELVSRVYNEGRGKVRFTQRAIESLKEHAWSGNVRELSNLVERL
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TILYPGGLVDVNDLPIKYRHIDVPEYSIELSEEQQERDALASIFTSEEPVEIPETRFPSE
HHCCCCCEEECCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LPPEGVNLKDLLAELEIDMIRQALEQQDNVVARAAEMLGIRRTTLVEKMRKYGMTKE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2881918; 11481430; 8478331 [H]