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The map label for this gene is yciR [C]

Identifier: 113969410

GI number: 113969410

Start: 1248105

End: 1249631

Strand: Direct

Name: yciR [C]

Synonym: Shewmr4_1066

Alternate gene names: 113969410

Gene position: 1248105-1249631 (Clockwise)

Preceding gene: 113969409

Following gene: 113969413

Centisome position: 26.52

GC content: 47.48

Gene sequence:

>1527_bases
ATGGTTATTCTGGGATTTATCGGTTTAGCATTGGTTATTATCTTGATAGCCGTGCTCTATATTTTACTTGCAAGATATCA
GGCTCTGCGGCTACAGCAGCGATTTTTGGCGCAGTTATGCCCCCAGCTCGATCAACAAAAGATTGAACGCCGCCCCCTTA
ATATTCCTATCGTGCCGCAGGAGTTTGCGCCCCTGTACCACTCCTTAAATGAGATGCTCGCAGCGCTGCCTGCGGGTATG
GGCAAGGACAAACTCACTGGGCTGAATAACCGTGTCGGACTCAAGCGCTCATTGACGGCTATGATGCCTATCACCCATGG
CACCTTAGTGCTCATCGATATCTATCGTTTTCGCTATGTGAATGATCTCTTTGGTTTTGTATTTGGGGATATTCTGCTTA
AACAGTTTGCCGATCGCTTAACCAGCTTAAGTCTTAAACCTAAGTTGATTGCGCGTCTAAACGGTGATGAGTTTTTCCTC
TATTACGAGCAAAGTCTGTCCGAGGAGCAATTGCTGCATTTACGTGGCCGTTTACAAGTTCCCTTTAAAATTAAAGATAC
GCCTGTGAGTGTGCGAATGCAGATTGGTTGTTTGCAATTGGCTGAGCACCATACCGATGTGAGCCATATGCTCAGAAGGC
TAGATCTCGCCCTTAAAAAGGCTCGTGCCACTCGCAGCGCTATCGCCTGTTACAGTGAGAATGACGATATTCGTCAGTTG
AGGGAGCTTAAGATTATCGACAGTCTTCCCAGTGGCTTACAGCGGAATCATTTGTATATGGTGTACCAGCCTAAGCAGGA
TATTCACACTGGAGCTTGCACCCAAGTAGAGGCTCTAATTCGCTGGGAGCATGAGGAACTCGGGTTTATTTCCCCCGCAG
AATTCATTCCGCTGGCAGAATGCGCCGGCATGATAGATCTAGTGAGCAATTGGGCGCTGGAGCAAGTGCTACAGCAGCAG
GTAAAGTGGCGTGTAGCAGGTATCTCTGTATGTGTGGCGCTTAATCTCTCGACCCGTGATCTCGATAGTGAAACCTTACC
CAATGAGATAGCGACCCGCCTCGAACATTATAAATTATCGCCAGAATGCTTAATGATTGAGATTACCGAAAGCACTCTGA
TGGCGGATTTAAACAAGGCCGTGGATACCTTGGAACAAATTCGTCGCCTTGGGGTGAAATTGGCGATCGATGATTTTGGC
ACAGGCCATTCATCGCTGGCGTATTTAAAGCATTTACCCGCCAATGAAGTCAAAATCGATAAAGCCTTTCTTCGGGATCT
TGAGCCGAATAAGCCCTCTGAATATATCCTTGAGGCCAGCATCAATATCGCTAAAAAGCTCGGCTACGAGGTGACAGTAG
AAGGTGTTGAAACGATCGAAGTCCATGATATGTTGGTGAATATGGGCGTCGATCGTATTCAAGGGATTGTTTATGCTAAG
CCTATGCGGGCCGCAGAGCTTGAAATGAACTGGGAGCAGCTTCGGCCAACGCCTGAAATGCTCTGCGTGAATGGTTCACA
TCCCTAG

Upstream 100 bases:

>100_bases
GAGAGTTACCAGTAGTCGTAGGGCCTAGAGGGAAGCCAATCTTACTCCGTGCTGGGGAGAATGGTGTATTAAGCTTACGT
GGTAAGATTGAGGCCAAACT

Downstream 100 bases:

>100_bases
GCTTAATTGGGTAATTAAGTCGGCGGGCATGGGCGCAAGTTGCCGAGCTTGATTCATACATACCATTTCGATAGTAGCCG
TAACCGCTGGTTTTTTACCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MVILGFIGLALVIILIAVLYILLARYQALRLQQRFLAQLCPQLDQQKIERRPLNIPIVPQEFAPLYHSLNEMLAALPAGM
GKDKLTGLNNRVGLKRSLTAMMPITHGTLVLIDIYRFRYVNDLFGFVFGDILLKQFADRLTSLSLKPKLIARLNGDEFFL
YYEQSLSEEQLLHLRGRLQVPFKIKDTPVSVRMQIGCLQLAEHHTDVSHMLRRLDLALKKARATRSAIACYSENDDIRQL
RELKIIDSLPSGLQRNHLYMVYQPKQDIHTGACTQVEALIRWEHEELGFISPAEFIPLAECAGMIDLVSNWALEQVLQQQ
VKWRVAGISVCVALNLSTRDLDSETLPNEIATRLEHYKLSPECLMIEITESTLMADLNKAVDTLEQIRRLGVKLAIDDFG
TGHSSLAYLKHLPANEVKIDKAFLRDLEPNKPSEYILEASINIAKKLGYEVTVEGVETIEVHDMLVNMGVDRIQGIVYAK
PMRAAELEMNWEQLRPTPEMLCVNGSHP

Sequences:

>Translated_508_residues
MVILGFIGLALVIILIAVLYILLARYQALRLQQRFLAQLCPQLDQQKIERRPLNIPIVPQEFAPLYHSLNEMLAALPAGM
GKDKLTGLNNRVGLKRSLTAMMPITHGTLVLIDIYRFRYVNDLFGFVFGDILLKQFADRLTSLSLKPKLIARLNGDEFFL
YYEQSLSEEQLLHLRGRLQVPFKIKDTPVSVRMQIGCLQLAEHHTDVSHMLRRLDLALKKARATRSAIACYSENDDIRQL
RELKIIDSLPSGLQRNHLYMVYQPKQDIHTGACTQVEALIRWEHEELGFISPAEFIPLAECAGMIDLVSNWALEQVLQQQ
VKWRVAGISVCVALNLSTRDLDSETLPNEIATRLEHYKLSPECLMIEITESTLMADLNKAVDTLEQIRRLGVKLAIDDFG
TGHSSLAYLKHLPANEVKIDKAFLRDLEPNKPSEYILEASINIAKKLGYEVTVEGVETIEVHDMLVNMGVDRIQGIVYAK
PMRAAELEMNWEQLRPTPEMLCVNGSHP
>Mature_508_residues
MVILGFIGLALVIILIAVLYILLARYQALRLQQRFLAQLCPQLDQQKIERRPLNIPIVPQEFAPLYHSLNEMLAALPAGM
GKDKLTGLNNRVGLKRSLTAMMPITHGTLVLIDIYRFRYVNDLFGFVFGDILLKQFADRLTSLSLKPKLIARLNGDEFFL
YYEQSLSEEQLLHLRGRLQVPFKIKDTPVSVRMQIGCLQLAEHHTDVSHMLRRLDLALKKARATRSAIACYSENDDIRQL
RELKIIDSLPSGLQRNHLYMVYQPKQDIHTGACTQVEALIRWEHEELGFISPAEFIPLAECAGMIDLVSNWALEQVLQQQ
VKWRVAGISVCVALNLSTRDLDSETLPNEIATRLEHYKLSPECLMIEITESTLMADLNKAVDTLEQIRRLGVKLAIDDFG
TGHSSLAYLKHLPANEVKIDKAFLRDLEPNKPSEYILEASINIAKKLGYEVTVEGVETIEVHDMLVNMGVDRIQGIVYAK
PMRAAELEMNWEQLRPTPEMLCVNGSHP

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=415, Percent_Identity=31.3253012048193, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI87081921, Length=417, Percent_Identity=30.2158273381295, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=35.7142857142857, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788849, Length=245, Percent_Identity=30.6122448979592, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI226510982, Length=442, Percent_Identity=27.8280542986425, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87081743, Length=247, Percent_Identity=30.7692307692308, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786507, Length=245, Percent_Identity=30.2040816326531, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788502, Length=233, Percent_Identity=30.4721030042918, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI87081845, Length=232, Percent_Identity=32.3275862068966, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081980, Length=234, Percent_Identity=30.7692307692308, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1787055, Length=274, Percent_Identity=27.7372262773723, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082096, Length=252, Percent_Identity=25.7936507936508, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787410, Length=152, Percent_Identity=26.9736842105263, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081977, Length=170, Percent_Identity=30.5882352941176, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 57651; Mature: 57651

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVILGFIGLALVIILIAVLYILLARYQALRLQQRFLAQLCPQLDQQKIERRPLNIPIVPQ
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCH
EFAPLYHSLNEMLAALPAGMGKDKLTGLNNRVGLKRSLTAMMPITHGTLVLIDIYRFRYV
HHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHH
NDLFGFVFGDILLKQFADRLTSLSLKPKLIARLNGDEFFLYYEQSLSEEQLLHLRGRLQV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCEEEEEECCCCCHHHHHHHCCCEEC
PFKIKDTPVSVRMQIGCLQLAEHHTDVSHMLRRLDLALKKARATRSAIACYSENDDIRQL
CEEECCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHH
RELKIIDSLPSGLQRNHLYMVYQPKQDIHTGACTQVEALIRWEHEELGFISPAEFIPLAE
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHCCCCCCHHHCCHHH
CAGMIDLVSNWALEQVLQQQVKWRVAGISVCVALNLSTRDLDSETLPNEIATRLEHYKLS
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCC
PECLMIEITESTLMADLNKAVDTLEQIRRLGVKLAIDDFGTGHSSLAYLKHLPANEVKID
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCEEHH
KAFLRDLEPNKPSEYILEASINIAKKLGYEVTVEGVETIEVHDMLVNMGVDRIQGIVYAK
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCHHHHCCEEEEC
PMRAAELEMNWEQLRPTPEMLCVNGSHP
CCCHHHHCCCHHHHCCCCCEEEECCCCC
>Mature Secondary Structure
MVILGFIGLALVIILIAVLYILLARYQALRLQQRFLAQLCPQLDQQKIERRPLNIPIVPQ
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCH
EFAPLYHSLNEMLAALPAGMGKDKLTGLNNRVGLKRSLTAMMPITHGTLVLIDIYRFRYV
HHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHH
NDLFGFVFGDILLKQFADRLTSLSLKPKLIARLNGDEFFLYYEQSLSEEQLLHLRGRLQV
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCEEEEEECCCCCHHHHHHHCCCEEC
PFKIKDTPVSVRMQIGCLQLAEHHTDVSHMLRRLDLALKKARATRSAIACYSENDDIRQL
CEEECCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHH
RELKIIDSLPSGLQRNHLYMVYQPKQDIHTGACTQVEALIRWEHEELGFISPAEFIPLAE
HHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHCCCCCCHHHCCHHH
CAGMIDLVSNWALEQVLQQQVKWRVAGISVCVALNLSTRDLDSETLPNEIATRLEHYKLS
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCC
PECLMIEITESTLMADLNKAVDTLEQIRRLGVKLAIDDFGTGHSSLAYLKHLPANEVKID
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCCCEEHH
KAFLRDLEPNKPSEYILEASINIAKKLGYEVTVEGVETIEVHDMLVNMGVDRIQGIVYAK
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCHHHHCCEEEEC
PMRAAELEMNWEQLRPTPEMLCVNGSHP
CCCHHHHCCCHHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]