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The map label for this gene is serB [H]

Identifier: 113969386

GI number: 113969386

Start: 1216165

End: 1217157

Strand: Direct

Name: serB [H]

Synonym: Shewmr4_1042

Alternate gene names: 113969386

Gene position: 1216165-1217157 (Clockwise)

Preceding gene: 113969384

Following gene: 113969387

Centisome position: 25.84

GC content: 53.27

Gene sequence:

>993_bases
ATGGAAAGCTTGAACCAAAATGCGCTGTTTGTATGGTTAGCTGCTAGCCCTTCACCTCGCTTTGAATATCAGGGGCTCAG
TTTCGAGGCTTATCAGGAATCGTCTACGCGGCCATCCCAGAGCGGATTTGCTATGCGTCTGATTTACGAAGATTTAAGCA
TTGAAGACTCATTAGCGGCTTGGATTGTTTCTCTAGCTGAAAGCCTCAAATTAACCTCGCTCTCCATCGCACCTATTCGC
CGTCAAGTGGCGCTGCATTGTGTGGAATTAGCGCTTCCCGTGGAGCCGAGTGCTGAGCTGTTAGCCACTTGTCCATCGCA
GGTGGAGTTACACCTTATTCGTGGCCCATTACCTAAACTGAGCGAACCTGGTTTACTGGTGATGGACATGGATTCTACCG
CGATCCAAATTGAATGTATTGATGAACTTGCCGCGATGGCAGGGGTCGGCGAGCAAGTGGCGGCGATCACAGAGCGCGCG
ATGCAGGGCGAGCTGGATTTCGAGCAGAGTTTGCGCCAAAGGGTTGCCCAGCTCGAGGGCACCGATGCCAAGATTATTCA
AACCTTGTGTGACACTTTGCCACTGATGCCGGGCCTTGAGGCCATGCTGACCGAGCTTAAGTCGCACCATTGGCGCCTCG
TTGTGGCCTCAGGCGGCTTTACGCCGTTCGTTGGTCACTTAAAACAGCTGTTGAATTTAGACGCTGCCTTTGCCAATGAA
TTAGTGATTGCGGACGGCAAGCTCGCGGGAACCGTCACGGGGAAAGTCGTCGATGCCCAGTTTAAGGCCGATGTGGTGAA
CCGTTGTAGCCAAGACTGGCAGATCCCTGTTGGGCAGCGTGTTGCCATCGGTGATGGTGCAAACGATATCCCTATGGTGC
AGGCGGCGGACTTTGGGATTGCCTTCCATGCTAAGCCTAAACTTGCGGCGGCGGCTGATGCGCGGATCCGCAGTTTAGAT
CTGCGGGTATTGCCTTATCTGCTGCAGTTTTAA

Upstream 100 bases:

>100_bases
TAGCCCTTTAAGATATAACACTTTGACCCTTAATAGTTAGAGCGCTTGCCTAATCATAATTGATTCTGAGTAAGCCCGAT
AGTTGGAGAACACGAGTCCT

Downstream 100 bases:

>100_bases
TTTATCCACTGTTTCCGAGTCGTGAACATTAGAGTAATGACTCTTGTTTTTTGACGCTTAGCTGGTAGTTTAGTGTTCAT
TAATGGACTACCAGCGACTG

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MESLNQNALFVWLAASPSPRFEYQGLSFEAYQESSTRPSQSGFAMRLIYEDLSIEDSLAAWIVSLAESLKLTSLSIAPIR
RQVALHCVELALPVEPSAELLATCPSQVELHLIRGPLPKLSEPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITERA
MQGELDFEQSLRQRVAQLEGTDAKIIQTLCDTLPLMPGLEAMLTELKSHHWRLVVASGGFTPFVGHLKQLLNLDAAFANE
LVIADGKLAGTVTGKVVDAQFKADVVNRCSQDWQIPVGQRVAIGDGANDIPMVQAADFGIAFHAKPKLAAAADARIRSLD
LRVLPYLLQF

Sequences:

>Translated_330_residues
MESLNQNALFVWLAASPSPRFEYQGLSFEAYQESSTRPSQSGFAMRLIYEDLSIEDSLAAWIVSLAESLKLTSLSIAPIR
RQVALHCVELALPVEPSAELLATCPSQVELHLIRGPLPKLSEPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITERA
MQGELDFEQSLRQRVAQLEGTDAKIIQTLCDTLPLMPGLEAMLTELKSHHWRLVVASGGFTPFVGHLKQLLNLDAAFANE
LVIADGKLAGTVTGKVVDAQFKADVVNRCSQDWQIPVGQRVAIGDGANDIPMVQAADFGIAFHAKPKLAAAADARIRSLD
LRVLPYLLQF
>Mature_330_residues
MESLNQNALFVWLAASPSPRFEYQGLSFEAYQESSTRPSQSGFAMRLIYEDLSIEDSLAAWIVSLAESLKLTSLSIAPIR
RQVALHCVELALPVEPSAELLATCPSQVELHLIRGPLPKLSEPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITERA
MQGELDFEQSLRQRVAQLEGTDAKIIQTLCDTLPLMPGLEAMLTELKSHHWRLVVASGGFTPFVGHLKQLLNLDAAFANE
LVIADGKLAGTVTGKVVDAQFKADVVNRCSQDWQIPVGQRVAIGDGANDIPMVQAADFGIAFHAKPKLAAAADARIRSLD
LRVLPYLLQF

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=31.3186813186813, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1790849, Length=207, Percent_Identity=57.9710144927536, Blast_Score=250, Evalue=9e-68,
Organism=Caenorhabditis elegans, GI115534456, Length=186, Percent_Identity=29.5698924731183, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534454, Length=186, Percent_Identity=29.5698924731183, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=211, Percent_Identity=42.1800947867299, Blast_Score=152, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35831; Mature: 35831

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLNQNALFVWLAASPSPRFEYQGLSFEAYQESSTRPSQSGFAMRLIYEDLSIEDSLAA
CCCCCCCEEEEEEECCCCCCCEECCCCEEHHHCCCCCCCCCCCEEEEEEECCCCCHHHHH
WIVSLAESLKLTSLSIAPIRRQVALHCVELALPVEPSAELLATCPSQVELHLIRGPLPKL
HHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEECCCCCC
SEPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITERAMQGELDFEQSLRQRVAQLEG
CCCCEEEEECCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TDAKIIQTLCDTLPLMPGLEAMLTELKSHHWRLVVASGGFTPFVGHLKQLLNLDAAFANE
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHCC
LVIADGKLAGTVTGKVVDAQFKADVVNRCSQDWQIPVGQRVAIGDGANDIPMVQAADFGI
EEEECCCEEEEEECEEEEHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEEECCCCE
AFHAKPKLAAAADARIRSLDLRVLPYLLQF
EEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MESLNQNALFVWLAASPSPRFEYQGLSFEAYQESSTRPSQSGFAMRLIYEDLSIEDSLAA
CCCCCCCEEEEEEECCCCCCCEECCCCEEHHHCCCCCCCCCCCEEEEEEECCCCCHHHHH
WIVSLAESLKLTSLSIAPIRRQVALHCVELALPVEPSAELLATCPSQVELHLIRGPLPKL
HHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEEEEEECCCCCC
SEPGLLVMDMDSTAIQIECIDELAAMAGVGEQVAAITERAMQGELDFEQSLRQRVAQLEG
CCCCEEEEECCCCEEEEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
TDAKIIQTLCDTLPLMPGLEAMLTELKSHHWRLVVASGGFTPFVGHLKQLLNLDAAFANE
CHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHCC
LVIADGKLAGTVTGKVVDAQFKADVVNRCSQDWQIPVGQRVAIGDGANDIPMVQAADFGI
EEEECCCEEEEEECEEEEHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEEECCCCE
AFHAKPKLAAAADARIRSLDLRVLPYLLQF
EEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]