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The map label for this gene is siaP [H]

Identifier: 113969277

GI number: 113969277

Start: 1089622

End: 1090737

Strand: Direct

Name: siaP [H]

Synonym: Shewmr4_0933

Alternate gene names: 113969277

Gene position: 1089622-1090737 (Clockwise)

Preceding gene: 113969276

Following gene: 113969278

Centisome position: 23.15

GC content: 51.7

Gene sequence:

>1116_bases
ATGCGTCATTTGGGGAGTCTATTGCTTGCGGTATTACTGATTGGACTCGGTGGGTGTAATCCTGCGCCTTCACAGACCGA
ACAGATTTCTGCATCGCCCCATCCTGACTCGACTCCCGTCAAAGAGGTGATTGAGTGGCGCTTAGCCACATCGTGGCCGA
AAAACTTCGCCGGTTTAGGTATGGCGCCTGAGCGTTTTGCTAAGTTGGTGAACGACATGTCCCATGGCCGTTTACAAATT
CATGTATATGGCGCGGGTGAGTTAATGCCGGCCTTTGCGGTATTCGACGGGGTGAGCCAAGGTAAAGTGCAGATGGCCCA
CGCCGCCTCCTATTATTGGAAGGGGAAAGCGCCCGCCTCACAGTTTTTTTCTTCTATCCCTTTTGGCATGACGGCCCAAG
AGATGAACGGCTGGCTGCATTATGGTGGCGGCATGGCACTGTGGGAGGAAGTCTATCGTCCCTTTGGTATTATTCCATTA
GCGGGTGGCAATACGGGCATGCAGATGGGCGGCTGGTTTAATAAACCCATCAACACTATTGCCGACTTTAAAGGCTTGAA
GATCCGTATGCCAGGCCTAGGGGGCGAAGTGCTGAAACGTGTCGGTGCCGTTCCCGTCAATATGGCTGGCAGGGAGCTTT
ATGGCGCTTTGCAAACGGGGTCGATTGATGCGGCGGAGTGGGTTGGGCCAGTAAACGATCTTGCCTTTGGCTTACATAAA
GTCGCCAAATATTACTATTATCCCGGCTGGCATGAGCCTGGCTCCAATATGGAGTTTTTGATCAATAAAGCCGCTTTTGA
GAGTCTGCCCGAAGATTTACAGGCCATAGTCAAAGGCGCGGCGCGTGCTATCAATCAAGATATGTTGGACGAATACACCA
CGCGTAACGTGACAGCCCTTGAAACCTTAGTAAAAGACGAGGGTGTGGTGCTGAAGGCATTCCCGCCCGAGGTGCTTAGC
GAGCTTGAACGTATTTCACAGCAGGTCATTGAAGAGCAGGCGGAGCAGGACCCTATGATGCGCAAAGTGTACCGCGCTTA
CCATGCGTATGAGCAAGGTGTACGTGAGTATCATAAAATTTCTGAAGATGCTTACAGCCAACAGCGGCAGCATTAA

Upstream 100 bases:

>100_bases
CAATATGTTTTATTTCAGCAGTGTTAAGCGTTCGTCGTTCGATAAAAGCACGCTAATTTTCATACTGTTAACTGGTTATT
TGTCTTGTGGGAGAGGTTTG

Downstream 100 bases:

>100_bases
TGCTGTCAATTTGAACAAAATGTTCATATTAGCGTCTGATTGATATGAGATGATTTCATCTTAGATTATCTTGTTATCGA
CCTAATCCATTTGGTGTTAT

Product: TRAP dicarboxylate transporter- DctP subunit

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRHLGSLLLAVLLIGLGGCNPAPSQTEQISASPHPDSTPVKEVIEWRLATSWPKNFAGLGMAPERFAKLVNDMSHGRLQI
HVYGAGELMPAFAVFDGVSQGKVQMAHAASYYWKGKAPASQFFSSIPFGMTAQEMNGWLHYGGGMALWEEVYRPFGIIPL
AGGNTGMQMGGWFNKPINTIADFKGLKIRMPGLGGEVLKRVGAVPVNMAGRELYGALQTGSIDAAEWVGPVNDLAFGLHK
VAKYYYYPGWHEPGSNMEFLINKAAFESLPEDLQAIVKGAARAINQDMLDEYTTRNVTALETLVKDEGVVLKAFPPEVLS
ELERISQQVIEEQAEQDPMMRKVYRAYHAYEQGVREYHKISEDAYSQQRQH

Sequences:

>Translated_371_residues
MRHLGSLLLAVLLIGLGGCNPAPSQTEQISASPHPDSTPVKEVIEWRLATSWPKNFAGLGMAPERFAKLVNDMSHGRLQI
HVYGAGELMPAFAVFDGVSQGKVQMAHAASYYWKGKAPASQFFSSIPFGMTAQEMNGWLHYGGGMALWEEVYRPFGIIPL
AGGNTGMQMGGWFNKPINTIADFKGLKIRMPGLGGEVLKRVGAVPVNMAGRELYGALQTGSIDAAEWVGPVNDLAFGLHK
VAKYYYYPGWHEPGSNMEFLINKAAFESLPEDLQAIVKGAARAINQDMLDEYTTRNVTALETLVKDEGVVLKAFPPEVLS
ELERISQQVIEEQAEQDPMMRKVYRAYHAYEQGVREYHKISEDAYSQQRQH
>Mature_371_residues
MRHLGSLLLAVLLIGLGGCNPAPSQTEQISASPHPDSTPVKEVIEWRLATSWPKNFAGLGMAPERFAKLVNDMSHGRLQI
HVYGAGELMPAFAVFDGVSQGKVQMAHAASYYWKGKAPASQFFSSIPFGMTAQEMNGWLHYGGGMALWEEVYRPFGIIPL
AGGNTGMQMGGWFNKPINTIADFKGLKIRMPGLGGEVLKRVGAVPVNMAGRELYGALQTGSIDAAEWVGPVNDLAFGLHK
VAKYYYYPGWHEPGSNMEFLINKAAFESLPEDLQAIVKGAARAINQDMLDEYTTRNVTALETLVKDEGVVLKAFPPEVLS
ELERISQQVIEEQAEQDPMMRKVYRAYHAYEQGVREYHKISEDAYSQQRQH

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG4663

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 41007; Mature: 41007

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHLGSLLLAVLLIGLGGCNPAPSQTEQISASPHPDSTPVKEVIEWRLATSWPKNFAGLG
CCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
MAPERFAKLVNDMSHGRLQIHVYGAGELMPAFAVFDGVSQGKVQMAHAASYYWKGKAPAS
CCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHH
QFFSSIPFGMTAQEMNGWLHYGGGMALWEEVYRPFGIIPLAGGNTGMQMGGWFNKPINTI
HHHHHCCCCCCHHHHCCEEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHH
ADFKGLKIRMPGLGGEVLKRVGAVPVNMAGRELYGALQTGSIDAAEWVGPVNDLAFGLHK
HCCCCCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
VAKYYYYPGWHEPGSNMEFLINKAAFESLPEDLQAIVKGAARAINQDMLDEYTTRNVTAL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ETLVKDEGVVLKAFPPEVLSELERISQQVIEEQAEQDPMMRKVYRAYHAYEQGVREYHKI
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SEDAYSQQRQH
HHHHHHHHCCC
>Mature Secondary Structure
MRHLGSLLLAVLLIGLGGCNPAPSQTEQISASPHPDSTPVKEVIEWRLATSWPKNFAGLG
CCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
MAPERFAKLVNDMSHGRLQIHVYGAGELMPAFAVFDGVSQGKVQMAHAASYYWKGKAPAS
CCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHH
QFFSSIPFGMTAQEMNGWLHYGGGMALWEEVYRPFGIIPLAGGNTGMQMGGWFNKPINTI
HHHHHCCCCCCHHHHCCEEEECCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHHH
ADFKGLKIRMPGLGGEVLKRVGAVPVNMAGRELYGALQTGSIDAAEWVGPVNDLAFGLHK
HCCCCCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHH
VAKYYYYPGWHEPGSNMEFLINKAAFESLPEDLQAIVKGAARAINQDMLDEYTTRNVTAL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ETLVKDEGVVLKAFPPEVLSELERISQQVIEEQAEQDPMMRKVYRAYHAYEQGVREYHKI
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SEDAYSQQRQH
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA